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  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Induction of NASH in the Nwd1−/− mouse liver via SERCA2-dependent endoplasmic reticulum stress
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    1. scibot 10 May 2024
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      DOI: 10.1101/2024.01.26.577307

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    biorxiv.org/content/10.1101/2024.01.26.577307v2
  3. Apr 2024
  4. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
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  5. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
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    embopress.org/doi/10.1038/s44319-024-00110-z
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    1. scibot 24 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury
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    1. scibot 24 Apr 2024
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      DOI: 10.7554/eLife.92243

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034944/
  8. www.sciencedirect.com www.sciencedirect.com
    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
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    sciencedirect.com/science/article/pii/S2211124724003954
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
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    sciencedirect.com/science/article/pii/S1550413124000500
  11. Feb 2024
  12. www.sciencedirect.com www.sciencedirect.com
    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
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    sciencedirect.com/science/article/pii/S2211124724000974
  13. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  14. Jan 2024
  15. www.sciencedirect.com www.sciencedirect.com
    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
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    1. scibot 11 Jan 2024
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    sciencedirect.com/science/article/pii/S1097276523010146
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    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  17. Nov 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis
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    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/abs/pii/S1074761323004582
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    sciencedirect.com/science/article/pii/S2211124723014894
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    Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease
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    sciencedirect.com/science/article/pii/S2211124723014481
  21. Oct 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
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      DOI: 10.1016/j.chembiol.2023.09.017

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    sciencedirect.com/science/article/pii/S2451945623003367
  23. www.science.org www.science.org
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
    1
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      DOI: 10.1126/sciadv.abo3610

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    science.org/doi/10.1126/sciadv.abo3610
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy
    1
    1. scibot 07 Oct 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10552648/
  25. www.cell.com www.cell.com
    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
    1
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    cell.com/cell-reports/abstract/S2211-1247(23)01092-6
  26. 52.53.155.43 52.53.155.43
    BPS Publications
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    52.53.155.43/6079453bbbf12bd08872d5439d37d8b14bece994/British J Pharmacology - 2023 - Chen - DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2-html.html
  27. Aug 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10425945/
  29. www.sciencedirect.com www.sciencedirect.com
    The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress
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  30. Jul 2023
  31. 52.53.155.43 52.53.155.43
    SSRN-id4280868-html.html
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    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
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    sciencedirect.com/science/article/pii/S2211124723007908
  33. Jun 2023
  34. 52.53.155.43 52.53.155.43
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    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
    1
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      DOI: 10.1016/j.stem.2023.05.015

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    sciencedirect.com/science/article/pii/S1934590923002114
  36. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  37. www.sciencedirect.com www.sciencedirect.com
    Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
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    sciencedirect.com/science/article/pii/S1934590923001753
  38. May 2023
  39. www.sciencedirect.com www.sciencedirect.com
    PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway
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    sciencedirect.com/science/article/pii/S2211124723005302
  40. www.nature.com www.nature.com
    Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
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      DOI: 10.1038/s41467-023-38165-6

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    nature.com/articles/s41467-023-38165-6
  41. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
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    sciencedirect.com/science/article/pii/S2211124723004588
  42. Apr 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determination of the autophagic flux in murine and human peripheral blood mononuclear cells
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      DOI: 10.3389/fcell.2023.1122998

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    ncbi.nlm.nih.gov/pmc/articles/PMC10040559/
  44. www.sciencedirect.com www.sciencedirect.com
    Myocardial structure and functional alterations in a preclinical model of exertional heat stroke
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      DOI: 10.1016/j.lfs.2023.121640

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    sciencedirect.com/science/article/pii/S0024320523002746
  45. Feb 2023
  46. link.springer.com link.springer.com
    Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy
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      DOI: 10.1186/s12915-023-01514-4

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    link.springer.com/article/10.1186/s12915-023-01514-4
  47. Dec 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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      DOI: 10.1016/j.celrep.2022.111834

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    sciencedirect.com/science/article/pii/S2211124722017260
  49. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  50. Nov 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin
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      DOI: 10.1016/j.ebiom.2022.104342

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    sciencedirect.com/science/article/pii/S2352396422005242
  52. Oct 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis
    1
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sox9 mediates Autophagy-dependent vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis
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      DOI: 10.1016/j.isci.2022.105161

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  55. Sep 2022
  56. www.sciencedirect.com www.sciencedirect.com
    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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  57. Aug 2022
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine metabolism modulates chondrocyte inflammatory response
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
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  60. Jul 2022
  61. academic.oup.com academic.oup.com
    T cells mediate kidney tubular injury via impaired PDHA1 and Autophagy in type 1 diabetes
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy
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  63. Mar 2022
  64. journals.lww.com journals.lww.com
    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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  65. Feb 2022
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway
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  67. Jan 2022
  68. link.springer.com link.springer.com
    Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells
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  69. Dec 2021
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Autophagy Response in Men and Women After Muscle Damage
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells
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  72. Oct 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
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  74. Sep 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity
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  76. Aug 2021
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apocynin prevents cigarette smoking‐induced loss of skeletal muscle mass and function in mice by preserving proteostatic signalling
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    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10
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  80. Jul 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells
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  82. Feb 2021
  83. www.mdpi.com www.mdpi.com
    Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones
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  84. link.springer.com link.springer.com
    Pancreatic beta cell autophagy is impaired in type 1 diabetes
    1
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      rabbit anti-LC3A/B

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  85. Jan 2021
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy
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  87. Sep 2020
  88. www.sciencedirect.com www.sciencedirect.com
    A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice
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  90. Jan 2020
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    Hantavirus Inhibits TRAIL-Mediated Killing of Infected Cells by Downregulating Death Receptor 5
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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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  93. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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      DOI: 10.1016/j.ccell.2019.01.006

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  96. www.sciencedirect.com www.sciencedirect.com
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    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
    1
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      DOI: 10.1016/j.cmet.2018.10.005

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  98. Nov 2018
  99. academic.oup.com academic.oup.com
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    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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    The cardioprotective effect of thymoquinone on ischemia‐reperfusion injury in isolated rat heart via regulation of apoptosis and autophagy
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    Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
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