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    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
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  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endoplasmic reticulum stress and autophagy in cerebral ischemia/reperfusion injury: PERK as a potential target for intervention
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    Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma
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    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
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  7. Nov 2024
  8. pubs.acs.org pubs.acs.org
    Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions
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    Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells
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    sciencedirect.com/science/article/pii/S2589004224024945
  10. Aug 2024
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    Contactin -Associated protein1 Regulates Autophagy by Modulating the PI3K/AKT/mTOR Signaling Pathway and ATG4B Levels in Vitro and in Vivo
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    Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
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  13. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
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    Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression
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  15. Jul 2024
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    Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice
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  18. May 2024
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    Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance
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  20. www.biorxiv.org www.biorxiv.org
    Induction of NASH in the Nwd1−/− mouse liver via SERCA2-dependent endoplasmic reticulum stress
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    biorxiv.org/content/10.1101/2024.01.26.577307v2
  21. Apr 2024
  22. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
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  23. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury
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    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
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  27. Mar 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
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  29. Feb 2024
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    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
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  31. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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  32. Jan 2024
  33. www.sciencedirect.com www.sciencedirect.com
    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
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    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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  35. Nov 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease
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  39. Oct 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
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      DOI: 10.1016/j.chembiol.2023.09.017

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  41. www.science.org www.science.org
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
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      DOI: 10.1126/sciadv.abo3610

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    science.org/doi/10.1126/sciadv.abo3610
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10552648/
  43. www.cell.com www.cell.com
    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
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    cell.com/cell-reports/abstract/S2211-1247(23)01092-6
  44. 52.53.155.43 52.53.155.43
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    52.53.155.43/6079453bbbf12bd08872d5439d37d8b14bece994/British J Pharmacology - 2023 - Chen - DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2-html.html
  45. Aug 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
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  47. www.sciencedirect.com www.sciencedirect.com
    The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress
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  48. Jul 2023
  49. 52.53.155.43 52.53.155.43
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    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
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  51. Jun 2023
  52. 52.53.155.43 52.53.155.43
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  53. www.sciencedirect.com www.sciencedirect.com
    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
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  54. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
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      DOI: 10.1158/0008-5472.CAN-22-2525

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  55. www.sciencedirect.com www.sciencedirect.com
    Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
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  56. May 2023
  57. www.sciencedirect.com www.sciencedirect.com
    PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway
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  58. www.nature.com www.nature.com
    Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
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  59. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
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  60. Apr 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determination of the autophagic flux in murine and human peripheral blood mononuclear cells
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    Myocardial structure and functional alterations in a preclinical model of exertional heat stroke
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  63. Feb 2023
  64. link.springer.com link.springer.com
    Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy
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  65. Dec 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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  68. Nov 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin
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  70. Oct 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sox9 mediates Autophagy-dependent vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis
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  73. Sep 2022
  74. www.sciencedirect.com www.sciencedirect.com
    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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  75. Aug 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine metabolism modulates chondrocyte inflammatory response
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
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  78. Jul 2022
  79. academic.oup.com academic.oup.com
    T cells mediate kidney tubular injury via impaired PDHA1 and Autophagy in type 1 diabetes
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy
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  81. Mar 2022
  82. journals.lww.com journals.lww.com
    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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  83. Feb 2022
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway
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  85. Jan 2022
  86. link.springer.com link.springer.com
    Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells
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  87. Dec 2021
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Autophagy Response in Men and Women After Muscle Damage
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells
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  90. Oct 2021
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    Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
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  92. Sep 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity
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  94. Aug 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apocynin prevents cigarette smoking‐induced loss of skeletal muscle mass and function in mice by preserving proteostatic signalling
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    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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      DOI: 10.1016/j.molcel.2019.03.021

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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10
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  98. Jul 2021
  99. www.sciencedirect.com www.sciencedirect.com
    Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells
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  100. Feb 2021
  101. www.mdpi.com www.mdpi.com
    Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones
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  102. link.springer.com link.springer.com
    Pancreatic beta cell autophagy is impaired in type 1 diabetes
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      rabbit anti-LC3A/B

      DOI: 10.1007/s00125-021-05387-6

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  103. Jan 2021
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy
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  105. Sep 2020
  106. www.sciencedirect.com www.sciencedirect.com
    A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice
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  108. Jan 2020
  109. www.sciencedirect.com www.sciencedirect.com
    Hantavirus Inhibits TRAIL-Mediated Killing of Infected Cells by Downregulating Death Receptor 5
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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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      DOI: 10.1016/j.molcel.2019.06.043

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    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
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  116. Nov 2018
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    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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  119. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The cardioprotective effect of thymoquinone on ischemia‐reperfusion injury in isolated rat heart via regulation of apoptosis and autophagy
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    Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria
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    Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein
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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
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