288 Matching Annotations
  1. Dec 2024
  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 13 Dec 2024
      RRID:AB_262011

      DOI: 10.1111/bph.17386

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17386
  3. www.sciencedirect.com www.sciencedirect.com
    Targeted macrophage mannose receptor (CD206)-specific protein delivery via engineered extracellular vesicles
    1
    1. scibot 12 Dec 2024
      RRID:AB_262011

      DOI: 10.1016/j.heliyon.2024.e40940

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    sciencedirect.com/science/article/pii/S240584402416971X
  4. www.sciencedirect.com www.sciencedirect.com
    Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease
    1
    1. scibot 02 Dec 2024
      RRID:AB_262011

      DOI: 10.1016/j.neuron.2024.10.029

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    sciencedirect.com/science/article/pii/S0896627324008006
  5. www.sciencedirect.com www.sciencedirect.com
    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
    1
    1. scibot 02 Dec 2024
      RRID:AB_262011

      DOI: 10.1016/j.celrep.2024.114984

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    sciencedirect.com/science/article/pii/S2211124724013354
  6. Nov 2024
  7. www.sciencedirect.com www.sciencedirect.com
    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
    1
    1. scibot 21 Nov 2024
      RRID:AB_262011

      DOI: 10.1016/j.molcel.2024.10.028

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    sciencedirect.com/science/article/pii/S1097276524008682
  8. www.sciencedirect.com www.sciencedirect.com
    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
    1
    1. scibot 16 Nov 2024
      RRID:AB_262011

      DOI: 10.1016/j.cell.2024.10.010

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    sciencedirect.com/science/article/pii/S0092867424011589
  9. Oct 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
    1
    1. scibot 02 Oct 2024
      AB_262011

      DOI: 10.1016/j.neuron.2024.09.006

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    sciencedirect.com/science/article/pii/S0896627324006548
  11. Sep 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins
    1
    1. scibot 25 Sep 2024
      RRID:AB_262011

      DOI: 10.7554/eLife.86920

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    ncbi.nlm.nih.gov/pmc/articles/PMC11412720/
  13. www.sciencedirect.com www.sciencedirect.com
    Microbiota regulates neonatal disease tolerance to virus-evoked necrotizing enterocolitis by shaping the STAT1-NLRC5 axis in the intestinal epithelium
    1
    1. scibot 25 Sep 2024
      RRID:AB_262011

      DOI: 10.1016/j.chom.2024.08.013

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    sciencedirect.com/science/article/pii/S1931312824003202
  14. www.sciencedirect.com www.sciencedirect.com
    Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
    1
    1. scibot 17 Sep 2024
      RRID:AB_262011

      DOI: 10.1016/j.apsb.2024.09.010

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    sciencedirect.com/science/article/pii/S2211383524003733
  15. Aug 2024
  16. www.sciencedirect.com www.sciencedirect.com
    TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation
    1
    1. scibot 22 Aug 2024
      RRID:AB_262011

      DOI: 10.1016/j.celrep.2024.114604

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    sciencedirect.com/science/article/pii/S2211124724009549
  17. link.springer.com link.springer.com
    Retinoic Acid Regulates Spermiogenesis Via Hoxb1 and Shh Signaling in Testicular Germ Cells
    1
    1. scibot 19 Aug 2024
      RRID:AB_262011

      DOI: 10.1007/s43032-024-01648-y

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    link.springer.com/article/10.1007/s43032-024-01648-y
  18. www.mdpi.com www.mdpi.com
    Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
    1
    1. scibot 02 Aug 2024
      A3854

      DOI: 10.3390/biomedicines9060599

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      Curator: @Naa003

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    mdpi.com/2227-9059/9/6/599/htm
  19. www.embopress.org www.embopress.org
    EDC3 phosphorylation regulates growth and invasion through controlling P‐body formation and dynamics
    1
    1. scibot 02 Aug 2024
      HRP‐conjugated anti‐β‐actin

      DOI: 10.15252/embr.202050835

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    embopress.org/doi/full/10.15252/embr.202050835
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    HOXA5 localization in postnatal and adult mouse brain is suggestive of regulatory roles in postmitotic neurons
    1
    1. scibot 02 Aug 2024
      AB_262011

      DOI: 10.1002/cne.24123

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      Curator: @gabimpine

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    onlinelibrary.wiley.com/doi/10.1002/cne.24123/full
  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroactive molecules and growth factors modulate cytoskeletal protein expression during astroglial cell proliferation and differentiation in culture
    2
    1. scibot 02 Aug 2024
      AB_262011

      DOI: 10.1002/jnr.23678

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    2. scibot 02 Aug 2024
      AB_262011

      DOI: 10.1002/jnr.23678

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    onlinelibrary.wiley.com/doi/10.1002/jnr.23678/full
  22. Jul 2024
  23. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
    1
    1. scibot 30 Jul 2024
      RRID:AB_262011

      DOI: 10.1101/2024.07.22.604482

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    biorxiv.org/content/10.1101/2024.07.22.604482v1
  24. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
    1
    1. scibot 25 Jul 2024
      AB_262011

      DOI: 10.1016/j.ccell.2024.06.012

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    sciencedirect.com/science/article/pii/S153561082400237X
  25. www.science.org www.science.org
    In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
    1
    1. scibot 18 Jul 2024
      RRID:AB_262011

      DOI: 10.1126/sciadv.adk2299

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    science.org/doi/10.1126/sciadv.adk2299
  26. Jun 2024
  27. www.science.org www.science.org
    In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
    2
    1. scibot 22 Jun 2024
      RRID:AB_262011

      DOI: 10.1126/sciadv.adk2299

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      RRID:AB_262011
    2. scibot 22 Jun 2024
      RRID:AB_262011

      DOI: 10.1126/sciadv.adk2299

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    science.org/doi/10.1126/sciadv.adk2299
  28. www.sciencedirect.com www.sciencedirect.com
    Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 contributes to neuronal function
    1
    1. scibot 05 Jun 2024
      RRID:AB_262011

      DOI: 10.1016/j.molcel.2024.05.011

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    sciencedirect.com/science/article/pii/S1097276524004349
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective regulation of chemosensitivity in glioblastoma by phosphatidylinositol 3-kinase beta
    1
    1. scibot 03 Jun 2024
      RRID:AB_262011

      DOI: 10.1016/j.isci.2024.109921

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    ncbi.nlm.nih.gov/pmc/articles/PMC11133927/
  30. May 2024
  31. www.biorxiv.org www.biorxiv.org
    Sex-focused analyses of M83 A53T hemizygous mouse model with recombinant human alpha-synuclein preformed fibril injection identifies female resilience to disease progression: A combined magnetic resonance imaging and behavioural study
    1
    1. scibot 30 May 2024
      RRID:AB_262011

      DOI: 10.1101/2024.05.24.595642

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    biorxiv.org/content/10.1101/2024.05.24.595642v1
  32. aacrjournals.org aacrjournals.org
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
    2
    1. scibot 23 May 2024
      RRID:AB_262011

      DOI: 10.1158/1078-0432.CCR-23-2951

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    2. scibot 23 May 2024
      RRID:AB_262011

      DOI: 10.1158/1078-0432.CCR-23-2951

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    aacrjournals.org/clincancerres/article/30/8/1582/742134/Discovery-of-a-Novel-Potent-EGFR-Inhibitor-Against
  33. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals
    1
    1. scibot 23 May 2024
      RRID:AB_262011

      DOI: 10.1016/j.molcel.2024.04.025

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    sciencedirect.com/science/article/pii/S1097276524003927
  34. academic.oup.com academic.oup.com
    Glycerol Phenylbutyrate treatment of two patients with Monocarboxylate Transporter 8 deficiency
    1
    1. scibot 22 May 2024
      RRID:AB_262011

      DOI: 10.1210/clinem/dgae146

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    academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgae146/7625621
  35. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model
    1
    1. scibot 16 May 2024
      RRID:AB_262011

      DOI: 10.1016/j.xcrm.2024.101570

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    sciencedirect.com/science/article/pii/S2666379124002623
  36. www.biorxiv.org www.biorxiv.org
    Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
    1
    1. scibot 10 May 2024
      RRID:AB_262011

      DOI: 10.1101/2024.01.24.577107

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    biorxiv.org/content/10.1101/2024.01.24.577107v1
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER-stress in mouse serotonin neurons triggers a depressive phenotype alleviated by ketamine targeting eIF2α signaling
    1
    1. scibot 09 May 2024
      RRID:AB_262011

      DOI: 10.1016/j.isci.2024.109787

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    ncbi.nlm.nih.gov/pmc/articles/PMC11070602/
  38. Apr 2024
  39. www.sciencedirect.com www.sciencedirect.com
    HSV-1 employs UL56 to antagonize expression and function of cGAMP channels
    1
    1. scibot 23 Apr 2024
      RRID:AB_262011

      DOI: 10.1016/j.celrep.2024.114122

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    sciencedirect.com/science/article/pii/S2211124724004509
  40. www.sciencedirect.com www.sciencedirect.com
    HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation
    1
    1. scibot 18 Apr 2024
      RRID:AB_262011

      DOI: 10.1016/j.celrep.2024.114103

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    sciencedirect.com/science/article/pii/S2211124724004315
  41. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
    1
    1. scibot 09 Apr 2024
      RRID:AB_262011

      DOI: 10.1016/j.cell.2024.03.015

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    sciencedirect.com/science/article/pii/S0092867424003064
  42. Mar 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MicroRNA-148b secreted by bovine oviductal extracellular vesicles enhance embryo quality through BPM/TGF-beta pathway
    1
    1. scibot 27 Mar 2024
      RRID:AB_262011

      DOI: 10.1186/s40659-024-00488-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960404/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ebola virus sequesters IRF3 in viral inclusion bodies to evade host antiviral immunity
    1
    1. scibot 23 Mar 2024
      RRID:AB_262011

      DOI: 10.7554/eLife.88122

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945704/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor
    1
    1. scibot 17 Mar 2024
      RRID:AB_262011

      DOI: 10.7554/eLife.90993

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942784/
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α-ACER2-Ceramide Signaling Axis
    1
    1. scibot 12 Mar 2024
      RRID:AB_262011

      DOI: 10.1002/advs.202309525

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    onlinelibrary.wiley.com/doi/10.1002/advs.202309525
  47. www.sciencedirect.com www.sciencedirect.com
    IκBζ is a dual-use coactivator of NF-κB and POU transcription factors
    2
    1. scibot 08 Mar 2024
      RRID:AB_262011

      DOI: 10.1016/j.molcel.2024.01.007

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    2. scibot 08 Mar 2024
      RRID:AB_262011

      DOI: 10.1016/j.molcel.2024.01.007

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    sciencedirect.com/science/article/pii/S109727652400008X
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R deficiency in vascular smooth muscle cells impairs myogenic autoregulation and cognition in mice
    1
    1. scibot 03 Mar 2024
      RRID:AB_262011

      DOI: 10.3389/fnagi.2024.1320808

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  49. Feb 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tangible method to assess native ferroptosis suppressor activity
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  51. www.sciencedirect.com www.sciencedirect.com
    Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons?
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    Brazilin is a natural product inhibitor of the NLRP3 inflammasome
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients
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    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
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  55. Dec 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Prothymosin α accelerates dengue virus-induced thrombocytopenia
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    SON is an essential m6A target for hematopoietic stem cell fate
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    Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability
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  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Leakage beyond the primary lesion: A temporal analysis of cerebrovascular dysregulation at sites of hippocampal secondary neurodegeneration following cortical photothrombotic stroke
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  60. Nov 2023
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    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
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  62. www.embopress.org www.embopress.org
    Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism
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    V-ATPase recruitment to ER exit sites switches COPII-mediated transport to lysosomal degradation
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    CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline
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  65. Oct 2023
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling
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  68. www.cell.com www.cell.com
    Tonic activin signaling shapes cellular and synaptic properties of CA1 neurons mainly in dorsal hippocampus
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    Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling
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  70. Sep 2023
  71. www.sciencedirect.com www.sciencedirect.com
    PARP1 inhibition protects mice against Japanese encephalitis virus infection
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    A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis
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    Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
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  74. Aug 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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  76. dx.doi.org dx.doi.org
    Mouse Testicular Mkrn3 Expression Is Primarily Interstitial, Increases Peripubertally, and Is Responsive to LH/hCG
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophages
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    The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages
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  79. Jul 2023
  80. www.sciencedirect.com www.sciencedirect.com
    Modeling epigenetic lesions that cause gliomas
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    Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones
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    Mechanism of orphan subunit recognition during assembly quality control
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    Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice
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    The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton
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    Loss of the importin Kpna2 causes infertility in male mice by disrupting the translocation of testis-specific transcription factors
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  86. Jun 2023
  87. 52.53.155.43 52.53.155.43
    CRISPR/Cas9-mediated generation of human embryonic stem cell sub-lines with HPRT1 gene knockout to model Lesch Nyhan disease
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    Phosphatidylinositol 4-kinase IIα is a glycogen synthase kinase 3-regulated interaction hub for activity-dependent bulk endocytosis
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    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
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    Pregnancy-associated steroid effects on insulin sensitivity, adipogenesis and lipogenesis: Role of Wnt/β-catenin pathway
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  91. dx.doi.org dx.doi.org
    Novel MKRN3 Missense Mutations Associated with Central Precocious Puberty Reveal Distinct Effects on Ubiquitination
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    Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation
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  93. May 2023
  94. www.sciencedirect.com www.sciencedirect.com
    Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome
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    Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release
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    MTHFD2 reprograms macrophage polarization by inhibiting PTEN
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    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
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  98. Apr 2023
  99. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity
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    AKT activity orchestrates marginal zone B cell development in mice and humans
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish
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  102. Mar 2023
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients
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    Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates
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  105. Jan 2023
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    CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy
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  107. Dec 2022
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    Erythroid SLC7A5/SLC3A2 amino acid carrier controls red blood cell size and maturation
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    Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia
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    Z-REX uncovers a bifurcation in function of Keap1 paralogs
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    Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence
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    Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation
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    CRISPR/Cas9 mediated approach to generate YAP-depleted human embryonic stem cell line (MUSIe002-A-1)
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  114. Nov 2022
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    Heat shock protein amplification improves cerebellar myelination in the Npc1nih mouse model
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    Size-Based Effects of Anthropogenic Ultrafine Particles on Lysosomal TRPML1 Channel and Autophagy in Motoneuron-like Cells
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  117. Oct 2022
  118. www.sciencedirect.com www.sciencedirect.com
    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
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  119. Sep 2022
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    Opioids Cause Sex-Specific Vascular Changes via Cofilin-Extracellular Signal-Regulated Kinase Signaling: Female Mice Present Higher Risk of Developing Morphine-Induced Vascular Dysfunction than Male Mice
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    Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
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  123. Jul 2022
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    Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS
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    NFIA determines the cis-effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth
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  127. Jun 2022
  128. www.sciencedirect.com www.sciencedirect.com
    IN BRAIN POST-ISCHEMIC PLASTICITY, Na+/Ca2+ EXCHANGER 1 AND Ascl1 INTERVENE IN MICROGLIA-DEPENDENT CONVERSION OF ASTROCYTES INTO NEURONAL LINEAGE
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    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
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    Insights into the Mechanism of Human Deiodinase 1
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  131. May 2022
  132. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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    PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson’s disease
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  134. Mar 2022
  135. www.sciencedirect.com www.sciencedirect.com
    Hormone-sensitive lipase is localized at synapses and is necessary for normal memory functioning in mice
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  136. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    Local hyperthermia therapy induces browning of white fat and treats obesity
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    Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency
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  139. Feb 2022
  140. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein
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    Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development
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  142. Jan 2022
  143. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development
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    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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  146. Dec 2021
  147. www.sciencedirect.com www.sciencedirect.com
    Na+/Ca2+ exchanger isoform 1 (NCX1) and canonical transient receptor potential channel 6 (TRPC6) are recruited by STIM1 to mediate Store-Operated Calcium Entry in primary cortical neurons
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  148. www.sciencedirect.com www.sciencedirect.com
    RNA circles with minimized immunogenicity as potent PKR inhibitors
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    Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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      DOI: 10.1016/j.isci.2021.103428

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633982/
  151. Nov 2021
  152. academic.oup.com academic.oup.com
    Nobiletin-induced partial abrogation of deleterious effects of AKT inhibition on preimplantation bovine embryo development in vitro
    1
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      RRID:AB_262011

      DOI: 10.1093/biolre/ioab184

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    academic.oup.com/biolreprod/advance-article/doi/10.1093/biolre/ioab184/6382539
  153. www.sciencedirect.com www.sciencedirect.com
    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
    1
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      DOI: 10.1016/j.immuni.2021.10.004

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    sciencedirect.com/science/article/pii/S1074761321004106
  154. www.nature.com www.nature.com
    AKIRIN2 controls the nuclear import of proteasomes in vertebrates
    1
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      DOI: 10.1038/s41586-021-04035-8

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    nature.com/articles/s41586-021-04035-8
  155. elifesciences.org elifesciences.org
    A functional genetic toolbox for human tissue-derived organoids
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      DOI: 10.7554/eLife.67886

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    elifesciences.org/articles/67886
  156. Oct 2021
  157. www.sciencedirect.com www.sciencedirect.com
    Aberrant RNA methylation triggers recruitment of an alkylation repair complex
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      AB_262011

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    sciencedirect.com/science/article/pii/S1097276521007772
  158. www.nature.com www.nature.com
    Role of hippocampal NF-κB and GluN2B in the memory acquisition impairment of experiences gathered prior to cocaine administration in rats
    1
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      DOI: 10.1038/s41598-021-99448-w

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  159. www.sciencedirect.com www.sciencedirect.com
    TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease
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      DOI: 10.1016/j.neuron.2021.09.031

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  160. www.sciencedirect.com www.sciencedirect.com
    Cholecystokinin 1 receptor activation restores normal mTORC1 signaling and is protective to Purkinje cells of SCA mice
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    sciencedirect.com/science/article/pii/S221112472101295X
  161. Sep 2021
  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma
    1
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      DOI: 10.3389/fcell.2021.718947

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  163. www.sciencedirect.com www.sciencedirect.com
    Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
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  164. elifesciences.org elifesciences.org
    Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa
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  165. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A
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      DOI: 10.1096/fj.202002745R

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  166. Aug 2021
  167. www.sciencedirect.com www.sciencedirect.com
    HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  169. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  171. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology
    1
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      AB_262011

      DOI: 10.1523/ENEURO.0004-17.2017

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  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/jnr.23678

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  174. www.jbc.org www.jbc.org
    Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe
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      DOI: 10.1074/jbc.RA118.005231

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  175. www.sciencedirect.com www.sciencedirect.com
    IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation
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      DOI: 10.1016/j.stem.2018.10.016

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    sciencedirect.com/science/article/pii/S1934590918304971
  176. Jul 2021
  177. mcr.aacrjournals.org mcr.aacrjournals.org
    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
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      anti-β-actin

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  178. www.sciencedirect.com www.sciencedirect.com
    An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
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      Mouse anti-Actin (1:5000)

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  179. www.sciencedirect.com www.sciencedirect.com
    Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
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      DOI: 10.1016/j.neuron.2018.10.014

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  180. www.sciencedirect.com www.sciencedirect.com
    Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
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      DOI: 10.1016/j.ccell.2019.05.003

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  181. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Japanese Encephalitis Virus‐induced let‐7a/b interacted with the NOTCH‐TLR7 pathway in microglia and facilitated neuronal death via caspase activation
    2
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      RRID_AB_262011

      DOI: 10.1111/jnc.14645

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      RRID:_AB_262011

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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology
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      AB_262011

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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.cell.2017.04.034

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  184. pubs.acs.org pubs.acs.org
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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      DOI: 10.1021/acsptsci.9b00001

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  185. www.sciencedirect.com www.sciencedirect.com
    Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
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  186. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
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      RRID:AB_262011

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  187. www.sciencedirect.com www.sciencedirect.com
    Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbed DNA methylation by Gadd45b induces chromatin disorganization, DNA strand breaks and dopaminergic neuron death
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  189. www.sciencedirect.com www.sciencedirect.com
    NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism
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  190. Jun 2021
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease
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      DOI: 10.1080/15548627.2020.1760014

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  192. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:AB_262011

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  193. www.sciencedirect.com www.sciencedirect.com
    DHX15 is required to control RNA virus-induced intestinal inflammation
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  194. www.sciencedirect.com www.sciencedirect.com
    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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      DOI: 10.1016/j.cell.2021.05.021

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  195. www.sciencedirect.com www.sciencedirect.com
    TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity
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  196. May 2021
  197. www.sciencedirect.com www.sciencedirect.com
    N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
    1
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      DOI: 10.1016/j.ccell.2021.04.017

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  198. link.springer.com link.springer.com
    Selective blood-nerve barrier leakiness with claudin-1 and vessel-associated macrophage loss in diabetic polyneuropathy
    1
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      RRID:AB_262011

      DOI: 10.1007/s00109-021-02091-1

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    link.springer.com/article/10.1007/s00109-021-02091-1
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes
    1
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      RRID:AB_262011

      DOI: 10.1126/sciadv.abf3873

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    ncbi.nlm.nih.gov/pmc/articles/PMC8087399/
  200. www.sciencedirect.com www.sciencedirect.com
    A high-throughput genome-wide RNAi screen identifies modifiers of survival motor neuron protein
    1
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      DOI: 10.1016/j.celrep.2021.109125

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    sciencedirect.com/science/article/pii/S2211124721004642
  201. journals.physiology.org journals.physiology.org
    Pharmacological inhibition of Vanin-1 is not protective in models of acute and chronic kidney disease
    1
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      DOI: 10.1152/ajprenal.00373.2020

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  202. academic.oup.com academic.oup.com
    A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling
    1
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  203. journals.physiology.org journals.physiology.org
    The β1 integrin plays a key role in lymphatic endothelial cell invasion in an optimized 3D Collagen matrix model
    1
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      DOI: 10.1152/ajpcell.00299.2020

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  204. www.sciencedirect.com www.sciencedirect.com
    Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function
    1
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  205. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
    1
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  206. www.sciencedirect.com www.sciencedirect.com
    Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation
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  207. Apr 2021
  208. www.sciencedirect.com www.sciencedirect.com
    The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation
    1
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  209. www.sciencedirect.com www.sciencedirect.com
    CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
    1
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  210. www.sciencedirect.com www.sciencedirect.com
    Mutant p53 suppresses innate immune signaling to promote tumorigenesis
    1
    1. scibot 22 Apr 2021
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  211. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
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  212. www.sciencedirect.com www.sciencedirect.com
    Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins
    1
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      DOI: 10.1016/j.xcrm.2021.100225

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  213. Mar 2021
  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
    1
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      DOI: 10.1186/s13024-021-00435-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC7941983/
  215. Feb 2021
  216. www.pnas.org www.pnas.org
    E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
    1
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      mouse anti–β-actin conjugated to HRP

      DOI: 10.1073/pnas.2015794118

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  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7269128/
  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
    1
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      DOI: 10.1021/acsptsci.9b00001

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  219. www.sciencedirect.com www.sciencedirect.com
    Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies
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      DOI: 10.1016/j.medj.2021.01.002

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    sciencedirect.com/science/article/pii/S2666634021000325
  220. www.sciencedirect.com www.sciencedirect.com
    Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
    1
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      RRID:AB_262011

      DOI: 10.1016/j.celrep.2021.108783

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    sciencedirect.com/science/article/pii/S2211124721000966
  221. www.sciencedirect.com www.sciencedirect.com
    CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition
    1
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      DOI: 10.1016/j.celrep.2021.108768

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  222. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
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      DOI: 10.1016/j.cell.2020.12.005

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    cell.com/cell/abstract/S0092-8674(20)31627-5
  223. Jan 2021
  224. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Lysosomal calcium is modulated by STIM1/TRPML1 interaction which participates to neuronal survival during ischemic preconditioning
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      DOI: 10.1096/fj.202001886R

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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202001886R
  225. Dec 2020
  226. www.mdpi.com www.mdpi.com
    Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux
    1
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      anti-β-actin

      DOI: 10.3390/antiox9121299

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  227. www.sciencedirect.com www.sciencedirect.com
    Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread
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      RRID:AB_262011

      DOI: 10.1016/j.celrep.2020.108409

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  228. Nov 2020
  229. elifesciences.org elifesciences.org
    LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation
    1
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      RRID:AB_262011

      DOI: 10.7554/eLife.59704

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  230. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Chronic administration of P2X7 receptor antagonist JNJ-47965567 delays disease onset and progression, and improves motor performance in ALS SOD1G93A female mice
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      RRID:AB_262011

      DOI: 10.1242/dmm.045732

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  231. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
    1
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      β-actin

      DOI: 10.3390/cancers12113269

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  232. www.sciencedirect.com www.sciencedirect.com
    Macrophage Immune Memory Controls Endometriosis in Mice and Humans
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  233. www.sciencedirect.com www.sciencedirect.com
    AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF
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      RRID:AB_262011

      DOI: 10.1016/j.celrep.2020.108329

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    sciencedirect.com/science/article/pii/S2211124720313188
  234. Oct 2020
  235. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM41B is a pan-flavivirus host factor
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      RRID:AB_262011

      DOI: 10.1101/2020.10.09.334128

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    ncbi.nlm.nih.gov/pmc/articles/PMC7553181/
  236. www.nature.com www.nature.com
    Suppression of proteolipid protein rescues Pelizaeus–Merzbacher disease
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      RRID:AB_262011

      DOI: 10.1038/s41586-020-2494-3

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  237. www.sciencedirect.com www.sciencedirect.com
    Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner
    1
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      RRID:AB_262011

      DOI: 10.1016/j.redox.2020.101742

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  238. Sep 2020
  239. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells
    1
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      RRID:AB_262011

      DOI: 10.3390/cancers12102749

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    pubmed.ncbi.nlm.nih.gov/32987811/
  240. www.sciencedirect.com www.sciencedirect.com
    Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells
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      RRID:AB_262011

      DOI: 10.1016/j.cell.2020.03.006

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    sciencedirect.com/science/article/pii/S0092867420302683