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A VHL-HIF signaling axis orchestrates invariant natural killer T cell development and fate decisions

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1. scibot 18 Aug 2026
  
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  DOI: 10.1016/j.devcel.2026.07.017
  
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sciencedirect.com/science/article/pii/S1534580726002868
Jul 2026
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Temporal control of macrophage pro-inflammatory phenotype by a biphasic HIF-1α regulatory program

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1. scibot 22 Jul 2026
  
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  DOI: 10.1016/j.molcel.2026.07.001
  
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sciencedirect.com/science/article/pii/S109727652600465X
May 2026
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Hypoxia-driven lncRNA SHIELD promotes GPX4 translation and protects against ferroptosis in hepatocellular carcinoma

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1. scibot 28 May 2026
  
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  DOI: 10.1016/j.molcel.2026.04.026
  
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sciencedirect.com/science/article/pii/S1097276526002807
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Adrenomedullin restores the human cortical interneurons migration defects induced by hypoxia

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1. scibot 19 May 2026
  
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  DOI: 10.7554/eLife.108134
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13179061/
Feb 2026
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BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.01.012
  
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sciencedirect.com/science/article/pii/S1097276526000328
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A conserved eIF1A+ luminal cell-centered hypoxic and “cold” tumor microenvironment promotes pan-subtype prostate cancer progression

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102619
  
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sciencedirect.com/science/article/pii/S2666379126000364
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Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer

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1. scibot 10 Feb 2026
  
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  DOI: 10.1038/s43856-025-01356-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12881505/
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Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3‐Inflammasome Activation in Macrophages

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1. scibot 04 Feb 2026
  
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  DOI: 10.1096/fj.202504083R
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12862736/
Nov 2025
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The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs

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1. scibot 18 Nov 2025
  
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  DOI: 10.1038/s41467-025-64983-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12618888/
Aug 2025
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PKD and scaffold NHERF1 mediate hypoxia-induced gene expression in 3T3-L1 adipocytes

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1. scibot 29 Aug 2025
  
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  DOI: 10.1530/JME-25-0011
  
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sciencedirect.com/org/science/article/pii/S1479681325000226
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jme-JME-25-0011-html.html

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1. scibot 20 Aug 2025
  
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  DOI: 10.1530/JME-25-0011
  
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52.53.155.43/25ff8971991199eba559b6c65cd9d78332cbc5b8/jme-JME-25-0011-html.html
Apr 2025
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Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.cmet.2025.03.003
  
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sciencedirect.com/science/article/pii/S1550413125001068
Mar 2025
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Keloid vasculature reacts to intralesional injection therapies but does not predict the response to treatment: Biopsies from double-blinded, randomized, controlled trial

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.bbadis.2025.167790
  
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sciencedirect.com/science/article/pii/S0925443925001358
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The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115403
  
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sciencedirect.com/science/article/pii/S2211124725001743
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HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.01.046
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11988688/
Feb 2025
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SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer

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1. scibot 11 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2330
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
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Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115267
  
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sciencedirect.com/science/article/pii/S2211124725000385
Dec 2024
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Nerve Growth Factor Signaling Promotes Nuclear Translocation of TRAF4 to Enhance Tumor Stemness and Metastatic Dormancy Via C-Jun-mediated IL-8 Autocrine

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1. scibot 29 Dec 2024
  
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  DOI: 10.1002/advs.202414437
  
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onlinelibrary.wiley.com/doi/full/10.1002/advs.202414437
Sep 2024
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A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein

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1. scibot 13 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114727
  
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sciencedirect.com/science/article/pii/S2211124724010787
Aug 2024
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Regulation of Glycolysis-Derived L-lactate Production in Astrocytes Rescues the Memory Deficits and Aβ Burden in Early Alzheimer’s Disease Models

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.phrs.2024.107357
  
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sciencedirect.com/science/article/pii/S1043661824003025
Jul 2024
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Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110415
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11295714/
Jun 2024
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Hypoxia-induced CTCF promotes EMT in breast cancer

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114367
  
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sciencedirect.com/science/article/pii/S2211124724006958
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Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer

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1. scibot 07 Jun 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-0519
  
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aacrjournals.org/cancerres/article/84/11/1834/745520/Obesogenic-High-Fat-Diet-and-MYC-Cooperate-to
May 2024
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Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia

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1. scibot 25 May 2024
  
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  DOI: 10.1113/JP285339
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP285339
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Monocyte bioenergetics: An immunometabolic perspective in metabolic dysfunction-associated steatohepatitis

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101564
  
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sciencedirect.com/science/article/pii/S2666379124002568
Feb 2024
www.jneurosci.org www.jneurosci.org

Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice

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1. scibot 16 Feb 2024
  
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  DOI: 10.1523/JNEUROSCI.1665-23.2023
  
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jneurosci.org/content/44/7/e1665232023
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The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113792
  
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sciencedirect.com/science/article/pii/S2211124724001207
Jan 2024
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JNEUROSCI.1665-23.2023.full-html.html

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1. scibot 26 Jan 2024
  
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  DOI: 10.1523/jneurosci.1665-23.2023
  
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  DOI: 10.1523/jneurosci.1665-23.2023
  
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52.53.155.43/9add5f7e7c84e06696c302815bac67f6cb4d2d58/JNEUROSCI.1665-23.2023.full (1)-html.html
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Augmentation of scleral glycolysis promotes myopia through histone lactylation

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.cmet.2023.12.023
  
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sciencedirect.com/science/article/pii/S1550413123004746
Nov 2023
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Hypoxia-sensitive cells trigger NK cell activation via the KLF4-ASH1L-ICAM-1 axis, contributing to impairment in the rat epididymis

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113442
  
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sciencedirect.com/science/article/pii/S2211124723014547
Oct 2023
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Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101238
  
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sciencedirect.com/science/article/pii/S2666379123004159
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Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance

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1. scibot 17 Oct 2023
  
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  DOI: 10.1126/sciadv.abo3610
  
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science.org/doi/10.1126/sciadv.abo3610
Jul 2023
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Circular RNA circPLOD2 regulates pericyte function by targeting the transcription factor KLF4

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112824
  
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sciencedirect.com/science/article/pii/S2211124723008355
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Induction of glioblastoma cell ferroptosis using combined treatment with chloramphenicol and 2-deoxy-d-glucose

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1. scibot 01 Jul 2023
  
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  DOI: 10.1038/s41598-023-37483-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10307808/
Jun 2023
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xCT-mediated glutamate excretion in white adipocytes stimulates interferon-γ production by natural killer cells in obesity

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  DOI: 10.1016/j.celrep.2023.112636
  
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May 2023
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Hypoxia-induced loss of SRSF2-dependent DNA methylation promotes CTCF-mediated alternative splicing of VEGFA in breast cancer

1
1. scibot 17 May 2023
  
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Apr 2023
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Mannose-coated nanozyme for relief from chemotherapy-induced peripheral neuropathic pain

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1. scibot 09 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106414
  
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Feb 2023
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Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis

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1. scibot 15 Feb 2023
  
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  DOI: 10.7554/eLife.86471
  
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Jan 2023
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GOT1 regulates CD8+ effector and memory T cell generation

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111987
  
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Dec 2022
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GABA regulates IL-1β production in macrophages

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  DOI: 10.1016/j.celrep.2022.111770
  
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Aug 2022
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Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance

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  DOI: 10.1126/sciadv.abo3610
  
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  DOI: 10.1126/sciadv.abo3610
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9299535/
Mar 2022
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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

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  DOI: 10.1016/j.celrep.2022.110511
  
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Nov 2021
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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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1. scibot 12 Nov 2021
  
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  DOI: 10.1016/j.immuni.2021.10.011
  
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Sep 2021
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Comparison of Histone H3K4me3 between IVF and ICSI Technologies and between Boy and Girl Offspring

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1. scibot 04 Sep 2021
  
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  DOI: 10.3390/ijms22168574
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8395251/
Aug 2021
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CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance

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1. scibot 18 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109549
  
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Jul 2021
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Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk

1
1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.celrep.2019.11.079
  
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Jun 2021
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Canagliflozin attenuates lipotoxicity in cardiomyocytes and protects diabetic mouse hearts by inhibiting the mTOR/HIF-1α pathway

1
1. scibot 18 Jun 2021
  
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  DOI: 10.1016/j.isci.2021.102521
  
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May 2021
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Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.immuni.2021.04.001
  
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Apr 2021
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Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation

1
1. scibot 30 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.12.001
  
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Sep 2020
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Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis

1
1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107607
  
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The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis

1
1. scibot 17 Sep 2020
  
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Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss

1
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  DOI: 10.1016/j.molcel.2020.01.009
  
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Jan 2020
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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2622225
  
  DOI: 10.1016/j.cmet.2019.10.015
  
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sciencedirect.com/science/article/pii/S1550413119306060
Nov 2018
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Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling

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Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53

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SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation

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MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

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ncbi.nlm.nih.gov/pmc/articles/PMC5650077/
Nov 2017
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Synaptic Activity Drives a Genomic Program That Promotes a Neuronal Warburg Effect

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