97 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development
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    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.devcel.2023.08.021

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    pmc.ncbi.nlm.nih.gov/articles/PMC7615346/
  3. Nov 2024
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    ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss
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    sciencedirect.com/science/article/pii/S1097276524008608
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Olanzapine enhances early brain maturation through activation of the NODAL/FOXH1 axis
    1
    1. scibot 07 Nov 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11519431/
  6. Sep 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
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    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124719315700
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    Dynamic allostery drives autocrine and paracrine TGF-β signaling
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    1. scibot 17 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009656
  9. Aug 2024
  10. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells
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      DOI: 10.1186/s12964-022-01033-9

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    biosignaling.biomedcentral.com/articles/10.1186/s12964-022-01033-9
  11. Jun 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration
    1
    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S2211124724006703
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    Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti
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    1. scibot 05 Jun 2024
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    sciencedirect.com/science/article/pii/S1550413124001761
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    Coordination between endoderm progression and mouse gastruloid elongation controls endodermal morphotype choice
    1
    1. scibot 05 Jun 2024
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    sciencedirect.com/science/article/pii/S1534580724003356
  15. May 2024
  16. 52.53.155.43 52.53.155.43
    2024.02.25.581951v1.full-html.html
    1
    1. scibot 16 May 2024
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      DOI: 10.1038/nature12362

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  17. Apr 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
    1
    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004777
  19. Mar 2024
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders
    1
    1. scibot 19 Mar 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC10940929/
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    Identification of key immune cells infiltrated in lung adenocarcinoma microenvironment and their related lncRNA
    2
    1. scibot 07 Mar 2024
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    2. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S2589004224004413
  22. Feb 2024
  23. www.sciencedirect.com www.sciencedirect.com
    Growth differentiation factor 9 regulates the expression of estrogen receptors via Smad2/3 signaling in goat cumulus cells
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    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.theriogenology.2024.02.021

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    sciencedirect.com/science/article/pii/S0093691X24000852
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    Sphingolipid metabolism controls mammalian heart regeneration
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    sciencedirect.com/science/article/pii/S1550413124000172
  25. Dec 2023
  26. www.sciencedirect.com www.sciencedirect.com
    EGFR-activated myofibroblasts promote metastasis of pancreatic cancer
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    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.ccell.2023.12.002

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    sciencedirect.com/science/article/pii/S1535610823004300
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    An oncogenic phenoscape of colonic stem cell polarization
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    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.cell.2023.11.004

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      DOI: 10.1016/j.cell.2023.11.004

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    sciencedirect.com/science/article/pii/S0092867423012217
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    Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses
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    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.cell.2023.11.005

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      DOI: 10.1016/j.cell.2023.11.005

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    sciencedirect.com/science/article/pii/S0092867423012205
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113564

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    sciencedirect.com/science/article/pii/S2211124723015760
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    Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling
    1
    1. scibot 16 Dec 2023
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    sciencedirect.com/science/article/pii/S1534580723006184
  31. Nov 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Deep learning untangles the resistance mechanism of p53 reactivator in lung cancer cells
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    1. scibot 29 Nov 2023
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      DOI: 10.1016/j.isci.2023.108377

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    sciencedirect.com/science/article/pii/S2589004223024549
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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
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    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.stem.2023.09.015

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    sciencedirect.com/science/article/pii/S1934590923003624
  34. Sep 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice
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    1. scibot 28 Sep 2023
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      DOI: 10.1016/j.xcrm.2023.101193

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    ncbi.nlm.nih.gov/pmc/articles/PMC10518624/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development
    1
    1. scibot 16 Sep 2023
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      DOI: 10.1016/j.devcel.2023.08.021

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  37. Jul 2023
  38. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
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    1. scibot 21 Jul 2023
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      DOI: 10.1111/bph.16190

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      DOI: 10.1111/bph.16190

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    52.53.155.43/01e7f498781407a431fc8d9b3b9cdd8be1437af6/British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
  39. May 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Cross-activation of FGF, NODAL, and WNT pathways constrains BMP-signaling-mediated induction of the totipotent state in mouse embryonic stem cells
    1
    1. scibot 03 May 2023
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      DOI: 10.1016/j.celrep.2023.112438

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    sciencedirect.com/science/article/pii/S2211124723004497
  41. Apr 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Protocol for analyzing transforming growth factor β signaling in dextran-sulfate-sodium-induced colitic mice using flow cytometry and western blotting
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    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.xpro.2023.102249

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    sciencedirect.com/science/article/pii/S2666166723002071
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    Sp1-like protein KLF13 acts as a negative feedback regulator of TGF-β signaling and fibrosis
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      DOI: 10.1016/j.celrep.2023.112367

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    sciencedirect.com/science/article/pii/S2211124723003789
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    Nodal coordinates the anterior-posterior patterning of germ layers and induces head formation in zebrafish explants
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      DOI: 10.1016/j.celrep.2023.112351

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    sciencedirect.com/science/article/pii/S2211124723003625
  45. Dec 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Nodal signaling establishes a competency window for stochastic cell fate switching
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      DOI: 10.1016/j.devcel.2022.11.008

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    sciencedirect.com/science/article/pii/S1534580722008085
  47. Nov 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial prophylactic effect of phlorotannins with photobiomodulation against tracheal stenosis
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      DOI: 10.1016/j.isci.2022.105405

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    ncbi.nlm.nih.gov/pmc/articles/PMC9664362/
  49. Oct 2022
  50. elifesciences.org elifesciences.org
    Regulation of Nodal signaling propagation by receptor interactions and positive feedback
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      DOI: 10.7554/eLife.66397

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    elifesciences.org/articles/66397
  51. journals.physiology.org journals.physiology.org
    Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes
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      DOI: 10.1152/ajpcell.00341.2022

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    journals.physiology.org/doi/10.1152/ajpcell.00341.2022
  52. Aug 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma
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      DOI: 10.1016/j.celrep.2022.111253

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    sciencedirect.com/science/article/pii/S2211124722010713
  54. Jul 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
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      DOI: 10.1016/j.celrep.2022.111066

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    sciencedirect.com/science/article/pii/S2211124722008646
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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      DOI: 10.1016/j.celrep.2022.111038

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    sciencedirect.com/science/article/pii/S2211124722008324
  57. Mar 2022
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15786

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  59. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  60. Feb 2022
  61. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways
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  62. Jan 2022
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    CXCL4 drives fibrosis by promoting several key cellular and molecular processes
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  66. Dec 2021
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    Effect of miR-183-5p on Cholestatic Liver Fibrosis by Regulating Fork Head Box Protein O1 Expression
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  68. Nov 2021
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  71. Oct 2021
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  73. Sep 2021
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    Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation
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  75. Aug 2021
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    Hormonally regulated myogenic miR-486 influences sex-specific differences in cancer-induced skeletal muscle defects
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    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
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  79. Jul 2021
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    CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota
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      Phospho-smad2 (Ser465/467)/Smad3 (Ser423/425) Rabbit mAb (D27F4)

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    Neuroplasticity and inflammatory alterations in the nucleus accumbens are corrected after risperidone treatment in a schizophrenia-related developmental model in rats
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    OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin
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  87. May 2021
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways
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  91. Apr 2021
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    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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      rabbit anti-phospho-Smad2 Ser465/467/ Smad3 Ser423/425

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  94. Feb 2021
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  96. Dec 2020
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  98. Oct 2020
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      Phospho-SMAD 2

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  101. Sep 2020
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    Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation
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    Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling
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    KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs
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    LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation
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    Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors
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      RRID:AB_2631089

      DOI: 10.3390/biom10040519

      Resource: (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_2631089
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    mdpi.com/2218-273X/10/4/519
  113. www.jci.org www.jci.org
    Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia
    1
    1. scibot 04 Sep 2020
      rabbit anti–phospho-SMAD2(S465/467)/SMAD3(S423/425)

      DOI: 10.1172/JCI131540

      Resource: (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2631089

      Curator comments: Phospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) (D27F4) Rabbit mAb antibody Cell Signaling Technology Cat# 8828

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    jci.org/articles/view/131540
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zebrafish embryonic explants undergo genetically encoded self-assembly
    1
    1. scibot 03 Sep 2020
      RRID:AB_2631089

      DOI: 10.7554/eLife.55190

      Resource: (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7190352/
  115. Jan 2020
  116. www.sciencedirect.com www.sciencedirect.com
    Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
    1
    1. scibot 13 Jan 2020
      RRID:AB_2631089

      DOI: 10.1016/j.cell.2019.11.026

      Resource: (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

      Curator: @ethanbadger

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419312838
  117. www.sciencedirect.com www.sciencedirect.com
    Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant
    1
    1. scibot 13 Jan 2020
      RRID:AB_2631089

      DOI: 10.1016/j.celrep.2019.07.092

      Resource: (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

      Curator: @ethanbadger

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719310083
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
    1
    1. scibot 13 Jan 2020
      RRID:AB_2631089

      DOI: 10.7554/eLife.47613

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      RRID:AB_2631089 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6561706/
  119. www.sciencedirect.com www.sciencedirect.com
    Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2631089

      DOI: 10.1016/j.celrep.2019.07.065

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719309696
  120. www.sciencedirect.com www.sciencedirect.com
    Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
    1
    1. scibot 13 Jan 2020
      RRID:AB_2631089

      DOI: 10.1016/j.cmet.2019.11.013

      Resource: (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413119306205
  121. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2631089

      DOI: 10.1016/j.molcel.2019.04.021

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519303132
  122. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2631089

      DOI: 10.1016/j.chembiol.2019.03.009

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945619301059
  123. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_2631089

      DOI: 10.1016/j.immuni.2018.11.003

      Resource: (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

      Curator: @ethanbadger

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761318304849
  124. Nov 2018
  125. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_2631089

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      (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

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    academic.oup.com/endo/article/159/9/3433/5060455
  126. www.sciencedirect.com www.sciencedirect.com
    Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis
    1
    1. scibot 05 Nov 2018
      AB_2631089

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    sciencedirect.com/science/article/pii/S1097276518304982
  127. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_2631089

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      (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

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    sciencedirect.com/science/article/pii/S0960982218302240
  128. www.sciencedirect.com www.sciencedirect.com
    Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages
    1
    1. scibot 05 Nov 2018
      RRID:AB_2631089

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      (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

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    sciencedirect.com/science/article/pii/S1534580717309826
  129. Nov 2017
  130. www.sciencedirect.com www.sciencedirect.com
    A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis
    1
    1. scibot 08 Nov 2017
      AB_2631089

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

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      RRID:AB_2631089 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717303404
  131. academic.oup.com academic.oup.com
    Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues
    1
    1. scibot 08 Nov 2017
      AB_2631089

      Curator: @bandrow

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      (Cell Signaling Technology Cat# 8828, RRID:AB_2631089)

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    academic.oup.com/endo/article/158/5/1217/2908842/Follistatin-Targets-Distinct-Pathways-To-Promote