180 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human-induced pluripotent stem cell-derived microglia integrate into mouse retina and recapitulate features of endogenous microglia
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      DOI: 10.7554/eLife.90695

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    pmc.ncbi.nlm.nih.gov/articles/PMC11587526/
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    Protocol for identifying sound-activated neurons in the inferior colliculus by cFos immunostaining
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    sciencedirect.com/science/article/pii/S2666166724006476
  4. Dec 2024
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    Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
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  6. Nov 2024
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila p53 tumor suppressor directly activates conserved asymmetric stem cell division regulators
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    Plausible, robust biological oscillations through allelic buffering
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    sciencedirect.com/science/article/pii/S2405471224002990
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    Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
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    embopress.org/doi/10.1038/s44318-024-00290-3
  10. 52.53.155.43 52.53.155.43
    wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
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    52.53.155.43/052dd78e8f9f0d46ee449e71fc9d1d608c537305/wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
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    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
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    Detecting altered hepatic lipid oxidation by MRI in an animal model of MASLD
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    pmc.ncbi.nlm.nih.gov/articles/PMC11525016/
  13. Oct 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
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    Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment
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    QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
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  17. Sep 2024
  18. www.pnas.org www.pnas.org
    An AAGAB-to-CCDC32 handover mechanism controls the assembly of the AP2 adaptor complex
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      DOI: 10.1073/pnas.2409341121

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    Intracellular Ebola virus nucleocapsid assembly revealed by in situ cryo-electron tomography
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    Deletion of histamine H2 receptor in VTA dopaminergic neurons of mice induces behavior reminiscent of mania
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    sciencedirect.com/science/article/pii/S2211124724010684
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    Targeting APT2 improves MAVS palmitoylation and antiviral innate immunity
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  22. Aug 2024
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    A dendritic mechanism for balancing synaptic flexibility and stability
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    The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
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  25. Jul 2024
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    A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation
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    sciencedirect.com/science/article/pii/S1097276524004830
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    The evolutionarily conserved choroid plexus contributes to the homeostasis of brain ventricles in zebrafish
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    cell.com/cell-reports/abstract/S2211-1247(24)00659-4
  28. www.cell.com www.cell.com
    Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine
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    miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
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    Lyssavirus matrix protein inhibits NLRP3 inflammasome assembly by binding to NLRP3
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    Notch2 signaling governs activated B cells to form memory B cells
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    The Spinocerebellar Ataxia 34-Causing W246G ELOVL4 Mutation Does Not Alter Cerebellar Neuron Populations in a Rat Model
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      DOI: 10.1007/s12311-024-01708-8

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    link.springer.com/article/10.1007/s12311-024-01708-8
  34. Jun 2024
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    Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
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    Protocol for generating three-dimensional induced early ameloblasts using serum-free media and growth factors
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    Capturing totipotency in human cells through spliceosomal repression
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    sciencedirect.com/science/article/pii/S0092867424005191
  39. May 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
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    sciencedirect.com/science/article/pii/S2451945624001818
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    TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery
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    sciencedirect.com/science/article/pii/S2211124724006223
  42. Apr 2024
  43. academic.oup.com academic.oup.com
    Granulosa cells alone, without theca cells, can mediate LH-induced oocyte meiotic resumption
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      DOI: 10.1210/endocr/bqad200

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    academic.oup.com/endo/article-abstract/165/3/bqad200/7511659
  44. Mar 2024
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Excitotoxic glutamate levels cause the secretion of resident endoplasmic reticulum proteins
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16093
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of SMN protein in mesenchymal progenitors impairs the development of bone and neuromuscular junction in spinal muscular atrophy
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      DOI: 10.7554/eLife.92731

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945524/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTOR pathway genes MTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function
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      DOI: 10.7554/eLife.91010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942629/
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    Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons
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    sciencedirect.com/science/article/pii/S2211124724002328
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    Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT
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  50. Feb 2024
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    Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs
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    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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  53. Jan 2024
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    Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing
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    A fluorescent splice-switching mouse model enables high-throughput, sensitive quantification of antisense oligonucleotide delivery and activity
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  56. Dec 2023
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    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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    Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion
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    In vivo identification of astrocyte and neuron subproteomes by proximity-dependent biotinylation
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      DOI: 10.1038/s41596-023-00923-7

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  60. Nov 2023
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    Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1
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  62. Oct 2023
  63. www.biorxiv.org www.biorxiv.org
    Parkinson’s-linked LRRK2-G2019S derails AMPAR trafficking, mobility and composition in striatum with cell-type and subunit specificity
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  64. Sep 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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    Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony
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  67. Aug 2023
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    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
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    NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophages
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    Diverse processing of pharmacological and natural rewards by the central amygdala
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  71. Jul 2023
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    PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics
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    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
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  74. Jun 2023
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    Circadian clocks are modulated by compartmentalized oscillating translation
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    Asynchronous transcription and translation of neurotransmitter-related genes characterize the initial stages of neuronal maturation in Drosophila
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  77. May 2023
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    The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging
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    Cerebellar granule cell signaling is indispensable for normal motor performance
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  80. Apr 2023
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    Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling
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    Potent, omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before omicron emergence
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    Conserved and cell type-specific transcriptional responses to IFN-γ in the ventral midbrain
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    Aggregating in vitro-grown adipocytes to produce macroscale cell-cultured fat tissue with tunable lipid compositions for food applications
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    Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
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  86. Mar 2023
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    Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest
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    Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila
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    Colchicine exerts anti-atherosclerotic and ‑plaque-stabilizing effects targeting foam cell formation
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    COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by upregulating Krox20
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    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
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    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
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    Neurovascular development in Pten and Tsc2 mouse mutants
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  94. Feb 2023
  95. www.nature.com www.nature.com
    Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs
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    Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays
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    OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum
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    Osteoblasts pattern endothelium and somatosensory axons during zebrafish caudal fin organogenesis
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    Dermal appendage-dependent patterning of zebrafish atoh1a+ Merkel cells
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  100. Jan 2023
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    Excitation-inhibition imbalance disrupts visual familiarity in amyloid and non-pathology conditions
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct niche structures and intrinsic programs of fallopian tube and ovarian surface epithelial cells
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  103. Dec 2022
  104. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-dependent suppression of biological pacemaker activity induced by TBX18
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    A porcine islet-encapsulation device that enables long-term discordant xenotransplantation in immunocompetent diabetic mice
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    A rapid RIG-I signaling relay mediates efficient antiviral response
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    A Pleomorphic Puzzle: Heterogeneous Pulmonary Vascular Occlusions in Patients with COVID-19
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    Excessive proteostasis contributes to pathology in fragile X syndrome
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    Generation of human iPSC line from an arrhythmogenic cardiomyopathy patient with a DSP protein-truncating variant
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  110. Nov 2022
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    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    Ptp61F integrates Hippo, TOR, and actomyosin pathways to control three-dimensional organ size
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    Identification of a GABAergic neuroblast lineage modulating sweet and bitter taste sensitivity
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    P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection
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    Hyper-excitability of corticothalamic PT neurons in mPFC promotes irritability in the mouse model of Alzheimer’s disease
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  116. Oct 2022
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    AAV-mediated gene therapy produces fertile offspring in the Lhcgr-deficient mouse model of Leydig cell failure
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    Developmental eye motion plasticity after unilateral embryonic ear removal in Xenopus laevis
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  119. Sep 2022
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    Myeloid Wls expression is dispensable for skin wound healing and blood vessel regeneration
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  121. Aug 2022
  122. journals.lww.com journals.lww.com
    Sequential expression of miR-221-3p and miR-338-3p in... : Neural Regeneration Research
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    Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations
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  124. Jul 2022
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    Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response
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  126. Jun 2022
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    Single unit analysis and wide-field imaging reveal alterations in excitatory and inhibitory neurons in glioma
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  128. www.sciencedirect.com www.sciencedirect.com
    Fat body-derived Spz5 remotely facilitates tumor-suppressive cell competition through Toll-6-α-Spectrin axis-mediated Hippo activation
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    Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila
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    Phenotypic and Histological Distribution Analysis Identify Mast Cell Heterogeneity in Non-Small Cell Lung Cancer
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  131. May 2022
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    Ribbon boosts ribosomal protein gene expression to coordinate organ form and function
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    Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons
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    Glutamate released by Cajal-Retzius cells impacts specific hippocampal circuits and behaviors
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    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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  136. Apr 2022
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    Anatomical distribution and functional roles of electrical synapses in Drosophila
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  138. Mar 2022
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    Mucus sialylation determines intestinal host-commensal homeostasis
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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    Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication
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    Insulin signaling couples growth and early maturation to cholesterol intake in Drosophila
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  144. Feb 2022
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    Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion
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    CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants
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  147. Jan 2022
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    Subcellular and regional localization of mRNA translation in midbrain dopamine neurons
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  149. Nov 2021
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    Distinct contributions of partial and full EMT to breast cancer malignancy
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  151. Sep 2021
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    TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons
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  153. journals.sagepub.com journals.sagepub.com
    Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice
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  154. Aug 2021
  155. www.sciencedirect.com www.sciencedirect.com
    Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis
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  156. www.sciencedirect.com www.sciencedirect.com
    Delivery of membrane impermeable molecules to primary mouse T lymphocytes
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    FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue
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  158. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  159. Jul 2021
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      DOI: 10.1016/j.chembiol.2018.11.003

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  161. pubs.acs.org pubs.acs.org
    A wash-free multiplexed mix-and-read suspension array fluorescence immunoassay for anthropogenic markers in wastewater
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    Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects
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    Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors
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    A double-negative gene regulatory circuit underlies the virgin behavioral state
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but not low-risk rats
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  166. Jun 2021
  167. elifesciences.org elifesciences.org
    A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma
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  168. May 2021
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    Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
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      Goat Alexa Fluor Plus 647 anti rabbit

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    Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
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    Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
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    Jararhagin, a snake venom metalloproteinase, induces mechanical hyperalgesia in mice with the neuroinflammatory contribution of spinal cord microglia and astrocytes
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  173. Apr 2021
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    The Lbx1 lineage differentially contributes to inhibitory cell types of the dorsal cochlear nucleus, a cerebellum‐like structure, and the cerebellum
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  177. Mar 2021
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    Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
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  179. www.sciencedirect.com www.sciencedirect.com
    Hedgehog signaling and Tre1 regulate actin dynamics through PI(4,5)P2 to direct migration of Drosophila embryonic germ cells
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  180. Feb 2021
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    Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice
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      DOI: 10.1016/j.neuron.2020.07.019

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    Generation of stress fibers through myosin-driven reorganization of the actin cortex
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    Whole-mount staining coupled to a UV-inducible basal cell carcinoma murine model
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  184. Jan 2021
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    Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells
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  186. Sep 2020
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    Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation
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    Unblending of Transcriptional Condensates in Human Repeat Expansion Disease
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    UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1
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      DOI: 10.1016/j.cub.2019.12.020

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    A Toolbox of Criteria for Distinguishing Cajal–Retzius Cells from Other Neuronal Types in the Postnatal Mouse Hippocampus
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      DOI: 10.1523/ENEURO.0516-19.2019

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    Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors
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    Axon-like protrusions promote small cell lung cancer migration and metastasis
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  193. Aug 2020
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    Diverse GABAergic neurons organize into subtype‐specific sublaminae in the ventral lateral geniculate nucleus
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  195. Jan 2020
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    Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models
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    Rat Model of Cockayne Syndrome Neurological Disease
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    Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
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    Tissue Architectural Cues Drive Organ Targeting of Tumor Cells in Zebrafish
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    TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
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    MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State
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    Separate vmPFC ensembles control cocaine self-administration versus extinction in rats
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      DOI: 10.1523/JNEUROSCI.0918-19.2019

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    Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development
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    Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch
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    TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
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      DOI: 10.1016/j.neuron.2019.12.007

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      DOI: 10.1016/j.neuron.2019.02.035

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      DOI: 10.1016/j.celrep.2019.01.069

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    Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition
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      DOI: 10.1016/j.neuron.2018.10.049

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  210. Nov 2018
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    Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling
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    Developmental Coordination during Olfactory Circuit Remodeling in Drosophila
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    Blockade of sustained tumor necrosis factor in a transgenic model of progressive autoimmune encephalomyelitis limits oligodendrocyte apoptosis and promotes oligodendrocyte maturation
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action
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    CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
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  218. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulatory connection between the expression level of classical protein kinase C and pruning of climbing fibers from cerebellar Purkinje cells
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    Myosin 2-Induced Mitotic Rounding Enables Columnar Epithelial Cells to Interpret Cortical Spindle Positioning Cues
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      A32733

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  220. Nov 2017
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    Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells
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      A32733

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    LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis
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    Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity - ScienceDirect
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    Genetically Distinct Parallel Pathways in the Entopeduncular Nucleus for Limbic and Sensorimotor Output of the Basal Ganglia
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      AB_2633282

      Curator: @gabimpine

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