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IDO1 methylation by EZH2 confers resistance to its targeted therapy in colorectal cancer through tryptophan-kynurenine metabolic rewiring

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118237
  
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sciencedirect.com/science/article/pii/S2211124726013161
Jun 2025
www.nature.com www.nature.com

Synergistic targeting of cancer cells through simultaneous inhibition of key metabolic enzymes

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1. scibot 24 Jun 2025
  
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  DOI: 10.1038/s41418-025-01532-5
  
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nature.com/articles/s41418-025-01532-5
May 2025
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Spatial and multiomics analysis of human and mouse lung adenocarcinoma precursors reveals TIM-3 as a putative target for precancer interception

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.003
  
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sciencedirect.com/science/article/pii/S153561082500162X
Jan 2025
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Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.immuni.2024.12.004
  
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sciencedirect.com/science/article/pii/S1074761324005685
Dec 2024
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Multi-modal analysis reveals tumor and immune features distinguishing EBV-positive and EBV-negative post-transplant lymphoproliferative disorders

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101851
  
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sciencedirect.com/science/article/pii/S2666379124006220
Nov 2024
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Microbiota-induced alteration of kynurenine metabolism in macrophages drives formation of creeping fat in Crohn’s disease

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.chom.2024.10.008
  
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sciencedirect.com/science/article/pii/S1931312824003949
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Laeverin/aminopeptidase Q induces indoleamine 2,3-dioxygenase-1 in human monocytes

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1. scibot 17 Sep 2023
  
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  RRID: AB_2636818
  
  DOI: 10.1016/j.isci.2023.107692
  
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2. scibot 17 Sep 2023
  
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  RRID:AB_2636818
  
  DOI: 10.1016/j.isci.2023.107692
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10495628/
May 2023
elifesciences.org elifesciences.org

Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction

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1. scibot 21 May 2023
  
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  DOI: 10.7554/eLife.82057
  
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elifesciences.org/articles/82057
Apr 2023
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PPRX-1701, a nanoparticle formulation of 6′-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models

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1. scibot 15 Apr 2023
  
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  DOI: 10.1016/j.xcrm.2023.101019
  
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sciencedirect.com/science/article/pii/S2666379123001295
Feb 2023
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An adverse tumor-protective effect of IDO1 inhibition

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.xcrm.2023.100941
  
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sciencedirect.com/science/article/pii/S2666379123000332
Mar 2022
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Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling

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1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.molcel.2022.02.007
  
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sciencedirect.com/science/article/pii/S1097276522001125
Jan 2022
elifesciences.org elifesciences.org

Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection

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1. scibot 29 Jan 2022
  
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  DOI: 10.7554/eLife.73137
  
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elifesciences.org/articles/73137
Sep 2021
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Oncogene-dependent sloppiness in mRNA translation

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1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.09.002
  
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sciencedirect.com/science/article/pii/S109727652100736X
May 2021
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Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.05.015
  
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sciencedirect.com/science/article/pii/S1097276520303166
Apr 2021
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Immunogenomic Landscape of Hematological Malignancies

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1. scibot 17 Apr 2021
  
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  RRID:AB_2636818
  
  DOI: 10.1016/j.ccell.2020.06.002
  
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  RRID:AB_2636818 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820302750
Feb 2021
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Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma

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1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.cell.2020.11.041
  
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sciencedirect.com/science/article/pii/S0092867420316135
www.cell.com www.cell.com

Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing

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1. scibot 24 Feb 2021
  
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  RRID:AB_2636818
  
  DOI: 10.1016/j.cell.2020.07.017
  
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cell.com/cell/fulltext/S0092-8674(20)30882-5
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0

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1. scibot 13 Feb 2021
  
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  RRID:AB_2636818
  
  DOI: 10.3389/fimmu.2020.609490
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7876453/
Dec 2020
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High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies

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1. scibot 07 Dec 2020
  
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  RRID:AB_2636818
  
  DOI: 10.1016/j.ebiom.2020.103131
  
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  RRIDCUR:Validated RRID:AB_2636818
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sciencedirect.com/science/article/pii/S2352396420305077
Sep 2020
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FOXD3 Regulates VISTA Expression in Melanoma

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1. scibot 03 Sep 2020
  
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  RRID:AB_2636818
  
  DOI: 10.1016/j.celrep.2019.12.036
  
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  Curator: @ethanbadger
  
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  RRID:AB_2636818 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S2211124719316936
Nov 2018
jlb.onlinelibrary.wiley.com jlb.onlinelibrary.wiley.com

Untitled document

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1. scibot 05 Nov 2018
  
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jlb.onlinelibrary.wiley.com/doi/full/10.1002/JLB.MA1217-495R