79 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
    1
    1. scibot 04 May 2024
      RRID:AB_2636929

      DOI: 10.1158/0008-5472.CAN-23-2268

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies
    1
    1. scibot 12 Mar 2024
      RRID:AB_2636929

      DOI: 10.1016/j.str.2024.02.007

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    sciencedirect.com/science/article/pii/S0969212624000467
  5. www.sciencedirect.com www.sciencedirect.com
    Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines
    2
    1. scibot 05 Mar 2024
      RRID:AB_2636929

      DOI: 10.1016/j.scr.2024.103374

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    2. scibot 05 Mar 2024
      RRID:AB_2636929

      DOI: 10.1016/j.scr.2024.103374

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    sciencedirect.com/science/article/pii/S1873506124000722
  6. Feb 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Brazilin is a natural product inhibitor of the NLRP3 inflammasome
    1
    1. scibot 08 Feb 2024
      AgilentCat# P026002-2

      DOI: 10.1016/j.isci.2024.108968

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    sciencedirect.com/science/article/pii/S2589004224001895
  8. Jan 2024
  9. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
    1
    1. scibot 25 Jan 2024
      RRID:AB_2636929

      DOI: 10.1016/j.molcel.2023.12.039

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    sciencedirect.com/science/article/pii/S1097276523010857
  10. www.sciencedirect.com www.sciencedirect.com
    The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.002

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    sciencedirect.com/science/article/pii/S1534580723006524
  11. www.sciencedirect.com www.sciencedirect.com
    Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.004

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    sciencedirect.com/science/article/pii/S0092867423013351
  12. Dec 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma
    1
    1. scibot 20 Dec 2023
      RRID:AB_2636929

      DOI: 10.1016/j.xcrm.2023.101302

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    sciencedirect.com/science/article/pii/S2666379123004962
  14. Aug 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble epoxide hydrolase maintains steady-state lipid turnover linked with autocrine signaling in peritoneal macrophages
    1
    1. scibot 26 Aug 2023
      RRID:AB_2636929

      DOI: 10.1016/j.isci.2023.107465

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    ncbi.nlm.nih.gov/pmc/articles/PMC10433125/
  16. Jul 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans
    1
    1. scibot 27 Jul 2023
      RRID:AB_2636929

      DOI: 10.1016/j.isci.2023.107354

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    sciencedirect.com/science/article/pii/S2589004223014311
  18. www.sciencedirect.com www.sciencedirect.com
    The Prc and CtpA proteases modulate cell-surface signaling activity and virulence in Pseudomonas aeruginosa
    1
    1. scibot 13 Jul 2023
      RRID:AB_2636929

      DOI: 10.1016/j.isci.2023.107216

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    sciencedirect.com/science/article/pii/S2589004223012932
  19. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
    1
    1. scibot 01 Jul 2023
      RRID:AB_2636929

      DOI: 10.1016/j.celrep.2023.112721

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    sciencedirect.com/science/article/pii/S2211124723007325
  20. Jun 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
    1
    1. scibot 16 Jun 2023
      RRID:AB_2636929

      DOI: 10.1016/j.isci.2023.106984

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    sciencedirect.com/science/article/pii/S2589004223010611
  22. May 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome
    1
    1. scibot 18 May 2023
      RRID:AB_2636929

      DOI: 10.1016/j.isci.2023.106758

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    sciencedirect.com/science/article/pii/S2589004223008350
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine
    1
    1. scibot 09 May 2023
      RRID:AB_2636929

      DOI: 10.1016/j.ebiom.2023.104574

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    ncbi.nlm.nih.gov/pmc/articles/PMC10159263/
  25. Apr 2023
  26. academic.oup.com academic.oup.com
    Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice
    1
    1. scibot 21 Apr 2023
      RRID:AB_2636929

      DOI: 10.1210/endocr/bqad034

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    academic.oup.com/endo/article/164/4/bqad034/7045509
  27. www.embopress.org www.embopress.org
    Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability
    1
    1. scibot 08 Apr 2023
      RRID:AB_2636929

      DOI: 10.15252/emmm.202216775

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    embopress.org/doi/10.15252/emmm.202216775
  28. Jan 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Fast and efficient synaptosome isolation and post-synaptic density enrichment from hiPSC-motor neurons by biochemical sub-cellular fractionation
    1
    1. scibot 26 Jan 2023
      RRID:AB_2636929

      DOI: 10.1016/j.xpro.2023.102061

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    sciencedirect.com/science/article/pii/S2666166723000199
  30. Oct 2022
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SSX addiction in melanoma propagates tumor growth and metastasis
    1
    1. scibot 25 Oct 2022
      AB_2636929

      DOI: 10.3389/fonc.2022.998000

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    ncbi.nlm.nih.gov/pmc/articles/PMC9585237/
  32. Sep 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters
    1
    1. scibot 15 Sep 2022
      RRID:AB_2636929

      DOI: 10.1016/j.isci.2022.105013

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    sciencedirect.com/science/article/pii/S2589004222012858
  34. www.sciencedirect.com www.sciencedirect.com
    A genetically modified minipig model for Alzheimer’s disease with SORL1 haploinsufficiency
    1
    1. scibot 13 Sep 2022
      RRID:AB_2636929

      DOI: 10.1016/j.xcrm.2022.100740

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    sciencedirect.com/science/article/pii/S2666379122002890
  35. www.sciencedirect.com www.sciencedirect.com
    The human mitochondrial genome contains a second light strand promoter
    1
    1. scibot 03 Sep 2022
      RRID:AB_2636929

      DOI: 10.1016/j.molcel.2022.08.011

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    sciencedirect.com/science/article/pii/S109727652200764X
  36. Aug 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells
    1
    1. scibot 17 Aug 2022
      RRID:AB_2636929

      DOI: 10.1016/j.celrep.2022.111182

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    sciencedirect.com/science/article/pii/S2211124722009950
  38. May 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury
    1
    1. scibot 27 May 2022
      AB_2636929

      DOI: 10.3389/fncel.2022.856734

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    ncbi.nlm.nih.gov/pmc/articles/PMC9130554/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
    1
    1. scibot 24 May 2022
      RRID:AB_2636929

      DOI: 10.7554/eLife.75594

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122501/
  41. Apr 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Characterization and functional interrogation of the SARS-CoV-2 RNA interactome
    1
    1. scibot 27 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110744

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    sciencedirect.com/science/article/pii/S2211124722005083
  43. www.sciencedirect.com www.sciencedirect.com
    DNA replication is highly resilient and persistent under the challenge of mild replication stress
    1
    1. scibot 20 Apr 2022
      RRID:AB_2636929

      DOI: 10.1016/j.celrep.2022.110701

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    sciencedirect.com/science/article/pii/S2211124722004594
  44. Feb 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae
    1
    1. scibot 12 Feb 2022
      RRID:AB_2636929

      DOI: 10.7554/eLife.73439

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    ncbi.nlm.nih.gov/pmc/articles/PMC8824476/
  46. Dec 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma
    1
    1. scibot 31 Dec 2021
      RRID:AB_2636929

      DOI: 10.1016/j.ccell.2021.12.006

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    sciencedirect.com/science/article/pii/S1535610821006590
  48. Oct 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing
    1
    1. scibot 29 Oct 2021
      RRID:AB_2636929

      DOI: 10.1016/j.cmet.2021.10.004

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    sciencedirect.com/science/article/pii/S1550413121004824
  50. Sep 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
    1
    1. scibot 23 Sep 2021
      RRID:AB_2636929

      DOI: 10.1016/j.molcel.2021.09.005

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    sciencedirect.com/science/article/pii/S1097276521007395
  52. Aug 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation
    1
    1. scibot 27 Aug 2021
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      DOI: 10.1016/j.scr.2021.102518

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    sciencedirect.com/science/article/pii/S1873506121003652
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NOTCH3 variant position is associated with NOTCH3 aggregation load in CADASIL vasculature
    1
    1. scibot 16 Aug 2021
      RRID:AB_2636929

      DOI: 10.1111/nan.12751

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    onlinelibrary.wiley.com/doi/10.1111/nan.12751
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 13 Aug 2021
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      DOI: 10.1016/j.immuni.2019.02.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC6477154/
  56. academic.oup.com academic.oup.com
    Untitled document
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      AB_2636929

      DOI: 10.1210/en.2016-1951

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    academic.oup.com/endo/article/158/6/1977/3078999
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 03 Aug 2021
      RRID:AB_2636929

      DOI: 10.1016/j.molcel.2018.11.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC6344341/
  58. Jul 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 30 Jul 2021
      RRID:AB_2636929

      DOI: 10.1016/j.ccell.2018.10.015

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    sciencedirect.com/science/article/pii/S1535610818304811
  60. www.embopress.org www.embopress.org
    VAP‐SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function
    1
    1. scibot 29 Jul 2021
      anti‐mouse anti‐HRP

      DOI: 10.15252/embj.2018101345

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    embopress.org/doi/abs/10.15252/embj.2018101345
  61. www.sciencedirect.com www.sciencedirect.com
    Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression
    1
    1. scibot 29 Jul 2021
      RRID:AB_2636929

      DOI: 10.1016/j.scr.2021.102473

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    sciencedirect.com/science/article/pii/S1873506121003202
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Wnt signaling reprograms metabolism in dental pulp stem cells
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1002/jcp.27977

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  63. www.sciencedirect.com www.sciencedirect.com
    Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization
    2
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      AB_2636929

      DOI: 10.1016/j.neuron.2017.04.042

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      AB_2636929

      DOI: 10.1016/j.neuron.2017.04.042

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    sciencedirect.com/science/article/pii/S0896627317303999
  64. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_2636929

      DOI: 10.1016/j.celrep.2018.11.062

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    Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5
    1
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      RRID:AB_263692

      DOI: 10.1016/j.celrep.2019.08.102

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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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      DOI: 10.1016/j.molcel.2021.06.017

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  67. May 2021
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein
    1
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      rabbit anti-mouse HRP-conjugated IgG

      DOI: 10.1002/ijc.33562

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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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      DOI: 10.1016/j.cell.2021.04.022

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    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes
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  71. www.cell.com www.cell.com
    The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia
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  72. Apr 2021
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    Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty
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    Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer
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  75. Mar 2021
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    PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
    1
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      DOI: 10.1016/j.molcel.2021.01.015

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  77. Dec 2020
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    Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation
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      DOI: 10.1016/j.celrep.2020.108523

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  79. Nov 2020
  80. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15275

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  81. elifesciences.org elifesciences.org
    LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation
    1
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      DOI: 10.7554/eLife.59704

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  82. Oct 2020
  83. www.jneurosci.org www.jneurosci.org
    Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR
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      DOI: 10.1523/JNEUROSCI.0957-20.2020

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  84. Sep 2020
  85. www.cell.com www.cell.com
    Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability
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      DOI: 10.1016/j.molcel.2018.11.001

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    cell.com/molecular-cell/abstract/S1097-2765(18)30943-2
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    Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo
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      DOI: 10.1016/j.celrep.2020.01.090

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    Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations
    1
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      DOI: 10.1016/j.str.2020.05.008

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  88. www.sciencedirect.com www.sciencedirect.com
    Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans
    1
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      RRID:AB_2636929

      DOI: 10.1016/j.celrep.2019.12.078

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  89. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
    1
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      DOI: 10.1016/j.devcel.2020.06.039

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    CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank
    1
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      RRID:AB_2636929

      DOI: 10.1016/j.stem.2020.01.019

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    sciencedirect.com/science/article/pii/S1934590920300199
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    Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation
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      RRID:AB_2636929

      DOI: 10.1016/j.scr.2020.101944

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  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bladder cancer therapy without toxicity ‐ A dose‐escalation study of alpha1‐oleate
    1
    1. scibot 03 Sep 2020
      polyclonal rabbit anti‐mouse IgG‐HRP

      DOI: 10.1002/ijc.33019

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  93. Jan 2020
  94. www.sciencedirect.com www.sciencedirect.com
    Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
    1
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      DOI: 10.1016/j.celrep.2019.07.070

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  95. www.sciencedirect.com www.sciencedirect.com
    IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2636929

      DOI: 10.1016/j.molcel.2019.05.036

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    Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage
    1
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      RRID:AB_2636929

      DOI: 10.1016/j.celrep.2019.05.003

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    Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
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      DOI: 10.1016/j.cell.2019.08.052

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  98. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.molcel.2018.11.001

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      DOI: 10.1016/j.str.2018.12.002

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  100. Nov 2018
  101. www.sciencedirect.com www.sciencedirect.com
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    Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
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    Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot–Marie–Tooth 1B Mouse Model
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    Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality
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    LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Acute and Rapid Degradation of Endogenous Proteins
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  107. Nov 2017
  108. www.sciencedirect.com www.sciencedirect.com
    Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis
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