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  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit
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    sciencedirect.com/science/article/pii/S2666379124006396
  3. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224027627-main-html.html
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  4. Oct 2024
  5. aacrjournals.org aacrjournals.org
    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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    aacrjournals.org/cancerdiscovery/article/10/12/1968/2414/H3-3-G34W-Promotes-Growth-and-Impedes
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11326252/
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    Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling
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    1. scibot 23 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724010155
  9. Jul 2024
  10. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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    cell.com/immunity/fulltext/S1074-7613(24)00348-0
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    Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner
    2
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    sciencedirect.com/science/article/pii/S2211124724008714
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    A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation
    1
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  13. www.cell.com www.cell.com
    Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
    1
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    cell.com/cell-reports/fulltext/S2211-1247(24)00678-8
  14. Mar 2024
  15. www.biorxiv.org www.biorxiv.org
    Transcriptomic and epigenomic consequences of heterozygous loss of function mutations in AKAP11, the first large-effect shared risk gene for bipolar disorder and schizophrenia
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1101/2024.03.14.584883

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  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma
    1
    1. scibot 03 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10542885/
  17. Jan 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Haplotype-specific assembly of shattered chromosomes in esophageal adenocarcinomas
    1
    1. scibot 19 Jan 2024
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    sciencedirect.com/science/article/pii/S2666979X23003361
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
    1
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    sciencedirect.com/science/article/pii/S2211124723015760
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Acid ceramidase regulates innate immune memory
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    Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development
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    sciencedirect.com/science/article/pii/S1534580723005555
  24. Sep 2023
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    Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells
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    Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma
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  27. Aug 2023
  28. 52.53.155.43 52.53.155.43
    mcr-22-0916-html.html
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  29. Jun 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Survivin prevents the Polycomb Repressor Complex 2 from methylating Histone 3 lysine 27
    1
    1. scibot 16 Jun 2023
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      DOI: 10.1016/j.isci.2023.106976

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    sciencedirect.com/science/article/pii/S2589004223010532
  31. Apr 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
    1
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      DOI: 10.1016/j.xgen.2023.100306

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  33. www.biorxiv.org www.biorxiv.org
    Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development
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  34. www.sciencedirect.com www.sciencedirect.com
    Genome graphs detect human polymorphisms in active epigenomic state during influenza infection
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  35. www.nature.com www.nature.com
    Regulation of human trophoblast gene expression by endogenous retroviruses
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    nature.com/articles/s41594-023-00960-6
  36. Mar 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
    1
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      DOI: 10.1158/2767-9764.CRC-22-0255

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    ncbi.nlm.nih.gov/pmc/articles/PMC9949381/
  38. europepmc.org europepmc.org
    Epigenetic dosage identifies two major and functionally distinct β cell subtypes
    1
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      DOI: 10.1016/j.cmet.2023.03.008

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    europepmc.org/article/med/36948185
  39. europepmc.org europepmc.org
    Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA biogenesis in mosquitoes
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      DOI: 10.1016/j.celrep.2023.112257

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    europepmc.org/article/med/36930642
  40. www.sciencedirect.com www.sciencedirect.com
    Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration
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      DOI: 10.1016/j.cell.2023.02.023

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    sciencedirect.com/science/article/pii/S0092867423001666
  41. www.sciencedirect.com www.sciencedirect.com
    Massively parallel characterization of CRISPR activator efficacy in human induced pluripotent stem cells and neurons
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      DOI: 10.1016/j.molcel.2023.02.011

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    sciencedirect.com/science/article/pii/S1097276523001144
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
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      DOI: 10.1158/2159-8290.CD-22-0424

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    ncbi.nlm.nih.gov/pmc/articles/PMC9975662/
  43. Jan 2023
  44. academic.oup.com academic.oup.com
    ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small intestine; a multi-omics study
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      DOI: 10.1093/nar/gkac1236

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1236/6981654
  45. Nov 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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      DOI: 10.1158/0008-5472.CAN-22-0671

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    ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
  47. Oct 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
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      DOI: 10.1158/2643-3230.BCD-21-0115

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    ncbi.nlm.nih.gov/pmc/articles/PMC9414116/
  49. Jul 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells
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      DOI: 10.3390/cells11152298

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    ncbi.nlm.nih.gov/pmc/articles/PMC9331440/
  51. Jun 2022
  52. link.springer.com link.springer.com
    Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
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      DOI: 10.1186/s13059-022-02702-1

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    link.springer.com/article/10.1186/s13059-022-02702-1
  53. May 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts
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    sciencedirect.com/science/article/pii/S2211124722005927
  55. Apr 2022
  56. www.sciencedirect.com www.sciencedirect.com
    The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes
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      DOI: 10.1016/j.stem.2022.03.015

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    sciencedirect.com/science/article/pii/S1934590922001503
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    Immune disease variants modulate gene expression in regulatory CD4+ T cells
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      DOI: 10.1016/j.xgen.2022.100117

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  58. Mar 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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      DOI: 10.7554/eLife.71094

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  61. Feb 2022
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    A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
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  63. Oct 2021
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    Epigenomic and Transcriptomic Dynamics During Human Heart Organogenesis
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  65. Aug 2021
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    NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior
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    ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
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    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
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    Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes
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    Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon
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  74. Jun 2021
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    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
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    Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth
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    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
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    Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
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    Stronger induction of trained immunity by mucosal BCG or MTBVAC vaccination compared to standard intradermal vaccination
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  92. Sep 2020
  93. www.cell.com www.cell.com
    Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
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    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
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    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
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    Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes
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  107. Nov 2018
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    The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity
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    A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
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    Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations
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    1. scibot 05 Nov 2018
      RRID:AB_2637079

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610818300047
  112. www.sciencedirect.com www.sciencedirect.com
    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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    1. scibot 05 Nov 2018
      RRID:AB_2637079

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    sciencedirect.com/science/article/pii/S1535610818300060
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
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    1. scibot 05 Nov 2018
      RRID:AB_2637079

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5989056/
  114. Nov 2017
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth
    1
    1. scibot 08 Nov 2017
      AB_2637079

      Curator: @gabimpine

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      (Diagenode Cat# C15410196, RRID:AB_2637079)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5461110/