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    A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation
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    Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
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    cell.com/cell-reports/abstract/S2211-1247(24)00678-8
  4. Mar 2024
  5. www.biorxiv.org www.biorxiv.org
    Transcriptomic and epigenomic consequences of heterozygous loss of function mutations in AKAP11, the first large-effect shared risk gene for bipolar disorder and schizophrenia
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    Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma
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  7. Jan 2024
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    Haplotype-specific assembly of shattered chromosomes in esophageal adenocarcinomas
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  9. Dec 2023
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  11. Nov 2023
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    Acid ceramidase regulates innate immune memory
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    Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development
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  14. Sep 2023
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    Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells
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    Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma
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  17. Aug 2023
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    mcr-22-0916-html.html
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  19. Jun 2023
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    Survivin prevents the Polycomb Repressor Complex 2 from methylating Histone 3 lysine 27
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  21. Apr 2023
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    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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    Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development
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    Genome graphs detect human polymorphisms in active epigenomic state during influenza infection
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    Regulation of human trophoblast gene expression by endogenous retroviruses
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  26. Mar 2023
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    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    Epigenetic dosage identifies two major and functionally distinct β cell subtypes
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    Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA biogenesis in mosquitoes
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    Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration
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    Massively parallel characterization of CRISPR activator efficacy in human induced pluripotent stem cells and neurons
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    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
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  33. Jan 2023
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    ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small intestine; a multi-omics study
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  35. Nov 2022
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    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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  37. Oct 2022
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    BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
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  39. Jul 2022
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    Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells
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  41. Jun 2022
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    Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
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  43. May 2022
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    Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts
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  45. Apr 2022
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    The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes
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    Immune disease variants modulate gene expression in regulatory CD4+ T cells
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  48. Mar 2022
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    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
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  51. Feb 2022
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    A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
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    sciencedirect.com/science/article/pii/S2211124722001413
  53. Oct 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic and Transcriptomic Dynamics During Human Heart Organogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7554226/
  55. Aug 2021
  56. www.sciencedirect.com www.sciencedirect.com
    NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior
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      DOI: 10.1016/j.neuron.2021.07.026

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    sciencedirect.com/science/article/pii/S0896627321005705
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    ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
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    sciencedirect.com/science/article/pii/S153561081930042X
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
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      DOI: 10.1016/j.cmet.2018.04.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC5989056/
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    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719312203
  60. Jul 2021
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    Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes
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    Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon
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  64. Jun 2021
  65. cancerres.aacrjournals.org cancerres.aacrjournals.org
    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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  66. May 2021
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    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
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    Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth
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    The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia
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    Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment
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  74. Mar 2021
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  76. Feb 2021
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    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
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  80. Jan 2021
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  82. Sep 2020
  83. www.cell.com www.cell.com
    Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
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    FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues
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    The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts
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    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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  89. Jan 2020
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock
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    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
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    TET2 Regulates the Neuroinflammatory Response in Microglia
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    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
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    Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes
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  97. Nov 2018
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    The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity
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    A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
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    Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations
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    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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  104. Nov 2017
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth
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