40 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
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    1. scibot 07 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.001

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    sciencedirect.com/science/article/pii/S0092867424004914
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.devcel.2024.05.001

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    sciencedirect.com/science/article/pii/S1534580724002995
  5. Mar 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.isci.2024.109400

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959657/
  7. Jan 2024
  8. www.sciencedirect.com www.sciencedirect.com
    A gut microbiota-bile acid axis promotes intestinal homeostasis upon aspirin-mediated damage
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.chom.2023.12.015

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    sciencedirect.com/science/article/pii/S1931312823005103
  9. www.science.org www.science.org
    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
    1
    1. scibot 18 Jan 2024
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      DOI: 10.1126/sciadv.adg4055

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    science.org/doi/10.1126/sciadv.adg4055
  10. Dec 2023
  11. link.springer.com link.springer.com
    Identification of druggable regulators of cell secretion via a kinome-wide screen and high-throughput immunomagnetic cell sorting
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1038/s41551-023-01135-w

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    link.springer.com/article/10.1038/s41551-023-01135-w
  12. Nov 2023
  13. www.nature.com www.nature.com
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
    1
    1. scibot 15 Nov 2023
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      DOI: 10.1038/s41467-023-43027-2

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    nature.com/articles/s41467-023-43027-2
  14. www.sciencedirect.com www.sciencedirect.com
    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.112659

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    sciencedirect.com/science/article/pii/S2211124723006708
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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.stem.2023.09.015

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    sciencedirect.com/science/article/pii/S1934590923003624
  16. Sep 2023
  17. www.sciencedirect.com www.sciencedirect.com
    LSR targets YAP to modulate intestinal Paneth cell differentiation
    1
    1. scibot 14 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113118

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    sciencedirect.com/science/article/pii/S2211124723011300
  18. Jul 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
    1
    1. scibot 14 Jul 2023
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      DOI: 10.1126/sciadv.adg4055

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    ncbi.nlm.nih.gov/pmc/articles/PMC10337909/
  20. May 2023
  21. www.science.org www.science.org
    BMP signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13–driven tuft cell hyperplasia
    1
    1. scibot 05 May 2023
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      DOI: 10.1126/sciimmunol.abl6543

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    science.org/doi/10.1126/sciimmunol.abl6543
  22. Mar 2023
  23. pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com
    CDK4/6 inhibitor modulating active and quiescent intestinal stem cells for prevention of chemotherapy-induced diarrhea
    1
    1. scibot 30 Mar 2023
      RRID:AB_2650511

      DOI: 10.1002/path.6078

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    pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6078
  24. Dec 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis
    1
    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111796

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    sciencedirect.com/science/article/pii/S2211124722016849
  26. Nov 2022
  27. www.sciencedirect.com www.sciencedirect.com
    A dietary change to a high-fat diet initiates a rapid adaptation of the intestine
    1
    1. scibot 16 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111641

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    sciencedirect.com/science/article/pii/S2211124722015121
  28. Sep 2022
  29. aacrjournals.org aacrjournals.org
    Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation
    1
    1. scibot 30 Sep 2022
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      DOI: 10.1158/0008-5472.CAN-22-0656

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    aacrjournals.org/cancerres/article/82/15/2678/707330/Orthovoltage-X-Rays-Exhibit-Increased-Efficacy
  30. www.sciencedirect.com www.sciencedirect.com
    Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection
    1
    1. scibot 29 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111416

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    sciencedirect.com/science/article/pii/S2211124722012578
  31. www.sciencedirect.com www.sciencedirect.com
    Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
    1
    1. scibot 03 Sep 2022
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      DOI: 10.1016/j.stem.2022.08.008

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    sciencedirect.com/science/article/pii/S1934590922003447
  32. Aug 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury
    1
    1. scibot 06 Aug 2022
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      DOI: 10.1016/j.stem.2022.07.007

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    sciencedirect.com/science/article/pii/S1934590922003022
  34. www.sciencedirect.com www.sciencedirect.com
    Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury
    1
    1. scibot 06 Aug 2022
      RRID:AB_2650511

      DOI: 10.1016/j.stem.2022.06.013

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    sciencedirect.com/science/article/pii/S1934590922002624
  35. Jul 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111053

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    sciencedirect.com/science/article/pii/S2211124722008476
  37. Jun 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Lymphatics act as a signaling hub to regulate intestinal stem cell activity
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.stem.2022.05.007

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    sciencedirect.com/science/article/pii/S1934590922002077
  39. Apr 2022
  40. academic.oup.com academic.oup.com
    G209R mutant mouse as a model for human PCSK1 polyendocrinopathy
    1
    1. scibot 29 Apr 2022
      RRID:AB_2650511

      DOI: 10.1210/endocr/bqac024

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    academic.oup.com/endo/article/163/5/bqac024/6542675
  41. Mar 2022
  42. www.nature.com www.nature.com
    Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop
    1
    1. scibot 05 Mar 2022
      RRID:AB_2650511

      DOI: 10.1038/s41419-022-04607-0

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    nature.com/articles/s41419-022-04607-0
  43. www.sciencedirect.com www.sciencedirect.com
    SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal
    1
    1. scibot 04 Mar 2022
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      DOI: 10.1016/j.devcel.2022.01.011

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    sciencedirect.com/science/article/pii/S1534580722000363
  44. Jan 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Adaptive differentiation promotes intestinal villus recovery
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1016/j.devcel.2021.12.012

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    sciencedirect.com/science/article/abs/pii/S1534580721010327
  46. Dec 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Generation of mixed murine organoids to model cellular interactions
    1
    1. scibot 09 Dec 2021
      RRID:AB_2650511

      DOI: 10.1016/j.xpro.2021.100997

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    sciencedirect.com/science/article/pii/S2666166721007036
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Enteric glial cell heterogeneity regulates intestinal stem cell niches
    1
    1. scibot 06 Nov 2021
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      DOI: 10.1016/j.stem.2021.10.004

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    sciencedirect.com/science/article/pii/S1934590921004161
  50. Sep 2021
  51. www.sciencedirect.com www.sciencedirect.com
    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
    1
    1. scibot 28 Sep 2021
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      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  52. Jul 2021
  53. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 30 Jul 2021
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      DOI: 10.1210/en.2018-00451

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    academic.oup.com/endo/article/159/9/3235/5055754
  54. Jun 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration
    1
    1. scibot 17 Jun 2021
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      DOI: 10.1016/j.xcrm.2021.100320

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    sciencedirect.com/science/article/pii/S2666379121001634
  56. www.sciencedirect.com www.sciencedirect.com
    High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity
    1
    1. scibot 09 Jun 2021
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      DOI: 10.1016/j.celrep.2021.109212

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    sciencedirect.com/science/article/pii/S2211124721005623
  57. May 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.06.021

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    sciencedirect.com/science/article/pii/S1934590920302885
  59. www.sciencedirect.com www.sciencedirect.com
    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
    1
    1. scibot 01 May 2021
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      DOI: 10.1016/j.molcel.2021.04.009

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    sciencedirect.com/science/article/pii/S1097276521003142
  60. Apr 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
    1
    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.cmet.2020.10.005

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    sciencedirect.com/science/article/pii/S1550413120305386
  62. Dec 2020
  63. elifesciences.org elifesciences.org
    Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival
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    1. scibot 09 Dec 2020
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      DOI: 10.7554/eLife.62377

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    elifesciences.org/articles/62377
  64. Sep 2020
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
    1
    1. scibot 14 Sep 2020
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      DOI: 10.1158/0008-5472.CAN-18-4075

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    ncbi.nlm.nih.gov/pmc/articles/PMC6726494/
  66. Nov 2018
  67. www.sciencedirect.com www.sciencedirect.com
    Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S2211124718312038
  68. www.sciencedirect.com www.sciencedirect.com
    Paneth Cell Multipotency Induced by Notch Activation following Injury
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1934590918302200
  69. www.sciencedirect.com www.sciencedirect.com
    Phospholipid Remodeling and Cholesterol Availability Regulate Intestinal Stemness and Tumorigenesis
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1934590917305192