48 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Maternal gut microbiota influence stem cell function in offspring
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    1. scibot 12 Dec 2024
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      DOI: 10.1016/j.stem.2024.10.003

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    sciencedirect.com/science/article/pii/S1934590924003655
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    FZD5 controls intestinal crypt homeostasis and colonic Wnt surrogate agonist response
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    sciencedirect.com/science/article/pii/S1534580724006622
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    Frizzled5 controls murine intestinal epithelial cell plasticity through organization of chromatin accessibility
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    IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells
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    1. scibot 02 Dec 2024
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    sciencedirect.com/science/article/pii/S2211124724012993
  6. Sep 2024
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    Protocol to characterize mouse intestinal epithelial cell lineage using Opal multiplex immunofluorescence
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    1. scibot 17 Sep 2024
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    sciencedirect.com/science/article/pii/S2666166724004684
  8. Aug 2024
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    An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation
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    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009689
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    Zinc transporter 1 functions in copper uptake and cuproptosis
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    1. scibot 19 Aug 2024
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    sciencedirect.com/science/article/pii/S1550413124002791
  11. Jul 2024
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    The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells
    1
    1. scibot 23 Jul 2024
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  13. Jun 2024
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    Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
    1
    1. scibot 07 Jun 2024
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    sciencedirect.com/science/article/pii/S0092867424004914
  15. May 2024
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    Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation
    1
    1. scibot 30 May 2024
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    sciencedirect.com/science/article/pii/S1534580724002995
  17. Mar 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis
    1
    1. scibot 27 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10959657/
  19. Jan 2024
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    A gut microbiota-bile acid axis promotes intestinal homeostasis upon aspirin-mediated damage
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.chom.2023.12.015

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    sciencedirect.com/science/article/pii/S1931312823005103
  21. www.science.org www.science.org
    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
    1
    1. scibot 18 Jan 2024
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      DOI: 10.1126/sciadv.adg4055

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  22. Dec 2023
  23. link.springer.com link.springer.com
    Identification of druggable regulators of cell secretion via a kinome-wide screen and high-throughput immunomagnetic cell sorting
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1038/s41551-023-01135-w

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    link.springer.com/article/10.1038/s41551-023-01135-w
  24. Nov 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
    1
    1. scibot 15 Nov 2023
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      DOI: 10.1038/s41467-023-43027-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
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    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.112659

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    sciencedirect.com/science/article/pii/S2211124723006708
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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.stem.2023.09.015

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    sciencedirect.com/science/article/pii/S1934590923003624
  28. Sep 2023
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    LSR targets YAP to modulate intestinal Paneth cell differentiation
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    1. scibot 14 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113118

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    sciencedirect.com/science/article/pii/S2211124723011300
  30. Jul 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
    1
    1. scibot 14 Jul 2023
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      DOI: 10.1126/sciadv.adg4055

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    ncbi.nlm.nih.gov/pmc/articles/PMC10337909/
  32. May 2023
  33. www.science.org www.science.org
    BMP signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13–driven tuft cell hyperplasia
    1
    1. scibot 05 May 2023
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      DOI: 10.1126/sciimmunol.abl6543

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    science.org/doi/10.1126/sciimmunol.abl6543
  34. Mar 2023
  35. pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com
    CDK4/6 inhibitor modulating active and quiescent intestinal stem cells for prevention of chemotherapy-induced diarrhea
    1
    1. scibot 30 Mar 2023
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      DOI: 10.1002/path.6078

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    pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6078
  36. Dec 2022
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    Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis
    1
    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111796

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    sciencedirect.com/science/article/pii/S2211124722016849
  38. Nov 2022
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    A dietary change to a high-fat diet initiates a rapid adaptation of the intestine
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    1. scibot 16 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111641

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    sciencedirect.com/science/article/pii/S2211124722015121
  40. Sep 2022
  41. aacrjournals.org aacrjournals.org
    Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation
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      DOI: 10.1158/0008-5472.CAN-22-0656

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    aacrjournals.org/cancerres/article/82/15/2678/707330/Orthovoltage-X-Rays-Exhibit-Increased-Efficacy
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    Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection
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    sciencedirect.com/science/article/pii/S2211124722012578
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    Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
    1
    1. scibot 03 Sep 2022
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      DOI: 10.1016/j.stem.2022.08.008

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    sciencedirect.com/science/article/pii/S1934590922003447
  44. Aug 2022
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    Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury
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      DOI: 10.1016/j.stem.2022.07.007

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    sciencedirect.com/science/article/pii/S1934590922003022
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    Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury
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      DOI: 10.1016/j.stem.2022.06.013

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    sciencedirect.com/science/article/pii/S1934590922002624
  47. Jul 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos
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      DOI: 10.1016/j.celrep.2022.111053

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    sciencedirect.com/science/article/pii/S2211124722008476
  49. Jun 2022
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    Lymphatics act as a signaling hub to regulate intestinal stem cell activity
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    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.stem.2022.05.007

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    sciencedirect.com/science/article/pii/S1934590922002077
  51. Apr 2022
  52. academic.oup.com academic.oup.com
    G209R mutant mouse as a model for human PCSK1 polyendocrinopathy
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      DOI: 10.1210/endocr/bqac024

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    academic.oup.com/endo/article-abstract/163/5/bqac024/6542675
  53. Mar 2022
  54. www.nature.com www.nature.com
    Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop
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      DOI: 10.1038/s41419-022-04607-0

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    nature.com/articles/s41419-022-04607-0
  55. www.sciencedirect.com www.sciencedirect.com
    SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal
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      DOI: 10.1016/j.devcel.2022.01.011

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    sciencedirect.com/science/article/pii/S1534580722000363
  56. Jan 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Adaptive differentiation promotes intestinal villus recovery
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      DOI: 10.1016/j.devcel.2021.12.012

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    sciencedirect.com/science/article/abs/pii/S1534580721010327
  58. Dec 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Generation of mixed murine organoids to model cellular interactions
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      DOI: 10.1016/j.xpro.2021.100997

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    sciencedirect.com/science/article/pii/S2666166721007036
  60. Nov 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Enteric glial cell heterogeneity regulates intestinal stem cell niches
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      DOI: 10.1016/j.stem.2021.10.004

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    sciencedirect.com/science/article/pii/S1934590921004161
  62. Sep 2021
  63. www.sciencedirect.com www.sciencedirect.com
    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
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      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  64. Jul 2021
  65. academic.oup.com academic.oup.com
    Untitled document
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      DOI: 10.1210/en.2018-00451

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    academic.oup.com/endo/article/159/9/3235/5055754
  66. Jun 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration
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      DOI: 10.1016/j.xcrm.2021.100320

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    sciencedirect.com/science/article/pii/S2666379121001634
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    High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity
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    1. scibot 09 Jun 2021
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      DOI: 10.1016/j.celrep.2021.109212

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    sciencedirect.com/science/article/pii/S2211124721005623
  69. May 2021
  70. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium
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      DOI: 10.1016/j.stem.2020.06.021

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    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
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      DOI: 10.1016/j.molcel.2021.04.009

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    sciencedirect.com/science/article/pii/S1097276521003142
  72. Apr 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
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    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.cmet.2020.10.005

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  74. Dec 2020
  75. elifesciences.org elifesciences.org
    Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival
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      DOI: 10.7554/eLife.62377

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  76. Sep 2020
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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      DOI: 10.1158/0008-5472.CAN-18-4075

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  78. Nov 2018
  79. www.sciencedirect.com www.sciencedirect.com
    Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
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    Paneth Cell Multipotency Induced by Notch Activation following Injury
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    Phospholipid Remodeling and Cholesterol Availability Regulate Intestinal Stemness and Tumorigenesis
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