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Cross-target and cell-preferential CRISPR-Cas9 inhibition with carbohydrate-tagged oligonucleotides

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  DOI: 10.1016/j.tibtech.2026.08.014
  
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sciencedirect.com/science/article/pii/S0167779926003677
Sep 2026
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IGF2 acts downstream of Hippo signaling to regulate organ growth and restore liver regeneration in aging

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  DOI: 10.1016/j.stem.2026.08.006
  
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sciencedirect.com/science/article/pii/S1934590926003073
Aug 2026
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L1CAM signaling through planar cell polarity drives SOX2 expression and lung adenocarcinoma metastasis

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pmc.ncbi.nlm.nih.gov/articles/PMC13434761/
Jul 2026
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HPV E5 Mediates Resistance to Chemotherapy and Radiation by Promoting a Stem Cell-Like Phenotype in Head and Neck Squamous Cell Carcinoma

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  DOI: 10.1158/0008-5472.CAN-24-3989
  
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aacrjournals.org/cancerres/article/85/20/3875/766093/HPV-E5-Mediates-Resistance-to-Chemotherapy-and
May 2026
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Early Surge in Brain GFAP Distribution in Female Hamsters With Mild Peripheral COVID-19

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  DOI: 10.1111/jnc.70437
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.70437
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Identification of CD74-positive antigen presenting glioma cells in primary human tumors and murine models of NF1 high-grade glioma

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  DOI: 10.1158/1535-7163.MCT-25-1215
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13204374/
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PGR-mediated transcriptome identifies SOX9 as a critical regulator of progesterone production in human ovulatory follicles

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  DOI: 10.1016/j.isci.2026.116044
  
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sciencedirect.com/science/article/pii/S2589004226014197
Mar 2026
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Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

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  DOI: 10.1016/j.celrep.2025.116794
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12974579/
Feb 2026
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Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1

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  DOI: 10.1158/0008-5472.CAN-25-2243
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12885529/
Dec 2025
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PRDM paralogs are required for Meckel's cartilage formation during mandibular bone development

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sciencedirect.com:5037/science/article/pii/S0012160625003331
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TGFα is required for hair follicle function during aging and its loss leads to progressive alopecia

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.jid.2025.11.007
  
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sciencedirect.com:5037/science/article/pii/S0022202X25036012
Aug 2025
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L1CAM signaling through planar cell polarity generates SOX2+ metastatic progenitors in lung adenocarcinoma

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1. scibot 27 Aug 2025
  
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  DOI: 10.1101/2025.08.22.671773
  
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biorxiv.org/content/10.1101/2025.08.22.671773v1
Jul 2025
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PRDM paralogs are required for Meckel’s cartilage formation during mandibular bone development

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1. scibot 30 Jul 2025
  
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  DOI: 10.1101/2025.07.17.665392
  
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biorxiv.org/content/10.1101/2025.07.17.665392v1
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FGF-induced phospholipase Cγ signaling regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism

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1. scibot 30 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116046
  
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cell.com/cell-reports/abstract/S2211-1247(25)00817-4
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1-s2.0-S0016508525057324-main-html.html

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1. scibot 08 Jul 2025
  
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  DOI: 10.1053/j.gastro.2025.07.003
  
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52.53.155.43/a363e4ae90be5a0c17cae72bbc9ca19379f34011/1-s2.0-S0016508525057324-main-html.html
May 2025
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The single-cell transcription reveals the aberrant differentiation trajectory of chondrocytes in the intervertebral disc for congenital scoliosis

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.isci.2025.112608
  
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sciencedirect.com/science/article/pii/S2589004225008697
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Hippo signaling is essential for the maintenance of zona glomerulosa cell fate in the murine adrenal cortex

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1. scibot 21 May 2025
  
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  DOI: 10.1210/endocr/bqaf077
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12041920/
Jan 2025
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Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity

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1. scibot 15 Jan 2025
  
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  DOI: 10.1038/s41467-024-55667-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11711318/
Dec 2024
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Self-organized pattern formation in the developing mouse neural tube by a temporal relay of BMP signaling

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  DOI: 10.1016/j.devcel.2024.10.024
  
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sciencedirect.com/science/article/pii/S1534580724006646
Oct 2024
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SOX10 mediates glioblastoma cell-state plasticity

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  DOI: 10.1038/s44319-024-00258-8
  
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embopress.org/doi/full/10.1038/s44319-024-00258-8
Jul 2024
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Cancer-associated endocrine cells participate in pancreatic carcinogenesis

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52.53.155.43/00ed7388bef43fd34d4811e77f0e00ce1748f907/1-s2.0-S0016508524052259-main-html.html
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TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration

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sciencedirect.com/science/article/pii/S2211124721002096
May 2024
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Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC11186085/
Apr 2024
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Craniofacial Chondrogenesis in Organoids from Human Stem Cell-Derived Neural Crest Cells

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52.53.155.43/c00e282857182b3d04ec5472d5421ef32ea8c27c/1-s2.0-S2589004224008071-main-html.html
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Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

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The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells

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sciencedirect.com/science/article/pii/S1534580724001837
Mar 2024
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Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance

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  DOI: 10.1016/j.celrep.2024.113897
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11209755/
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TLR2 regulates hair follicle cycle and regeneration via BMP signaling

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  DOI: 10.7554/eLife.89335
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10939499/
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Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma

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  DOI: 10.1158/1535-7163.MCT-23-0025
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
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ALK upregulates POSTN and WNT signaling to drive neuroblastoma

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  DOI: 10.1016/j.celrep.2024.113927
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
Feb 2024
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Proteogenomic characterization of primary colorectal cancer and metastatic progression identifies proteome-based subtypes and signatures

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  DOI: 10.1016/j.celrep.2024.113810
  
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sciencedirect.com/science/article/pii/S2211124724001384
Jan 2024
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Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis

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  DOI: 10.1016/j.celrep.2024.113703
  
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sciencedirect.com/science/article/pii/S2211124724000317
Dec 2023
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Multipotent progenitors instruct ontogeny of the superior colliculus

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  DOI: 10.1016/j.neuron.2023.11.009
  
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sciencedirect.com/science/article/pii/S0896627323008838
Nov 2023
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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.devcel.2023.10.010
  
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TGFB1 induces fetal reprogramming and enhances intestinal regeneration

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1. scibot 10 Nov 2023
  
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Single-cell and spatial analyses reveal a tradeoff between murine mammary proliferation and lineage programs associated with endocrine cues

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Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling

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mct-23-0025 (1)-html.html

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Deconstructing olfactory epithelium developmental pathways in olfactory neuroblastoma

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Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities

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Two Hippo signaling modules orchestrate liver size and tumorigenesis

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The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model

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The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response

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Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation

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NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma

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The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling

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Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers

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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

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Xeno-free culture for generation of forebrain oligodendrocyte precursor cells from human pluripotent stem cells

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CCAAT/Enhancer-Binding Protein Alpha Is a Novel Regulator of Vascular Smooth Muscle Cell Osteochondrogenic Transition and Vascular Calcification

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Inhibition of FGFR Signaling Partially Rescues Osteoarthritis in Mice Overexpressing High Molecular Weight FGF2 Isoforms

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Cell Lineage-Based Stratification for Glioblastoma

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TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration

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CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes

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Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer

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Proteogenomic and metabolomic characterization of human glioblastoma

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CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes

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Self-Organizing 3D Human Trunk Neuromuscular Organoids

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Human axial progenitors generate trunk neural crest cells in vitro

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miR-29a/b1 Inhibits Hair Follicle Stem Cell Lineage Progression by Spatiotemporally Suppressing WNT and BMP Signaling

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Untitled document

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Conditional Deletion of FOXL2 and SMAD4 in Gonadotropes of Adult Mice Causes Isolated FSH Deficiency

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