134 Matching Annotations
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    TECR palmitoylation triggers a necrotic cell death program driving acute liver injury
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  3. Oct 2026
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    Early infiltration of ischemia-conditioned Tregs attenuates BBB damage via suppressing neutrophil extracellular traps in ischemic stroke
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    PYGO2 Ablation Promotes Lymphoid Organization and STING-Dependent Antitumor Immunity in Prostate Cancer
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    Establishment of a colorectal cancer liver metastasis (CRCLM) solitary tumor mouse model
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    KRAS Inhibitor–Induced Cancer Cell Death Enhances Sensitivity to Immune-Mediated Bystander Killing of Drug-Resistant Subclones
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    Enfortumab vedotin induces immunogenic cell death and shows enhanced preclinical antitumor activity when combined with a PD-1 inhibitor
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  10. Aug 2026
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    Genetically driven immune microenvironment states associate with therapeutic responses in MYD88 mutant lymphomas
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    Claudin-12 sustains urothelial barrier defense against uropathogenic E. coli via calcium-dependent immunomodulation
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    UV irradiation drives lineage-specific MITF-mediated transcription of PD-L1 to confer immune tolerance to UV-mutated melanocytes
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    AI-driven discovery and validation of a GIPC1 PDZ domain inhibitor for pancreatic ductal adenocarcinoma
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    Circulating memory-phenotype CD4+ T cells rapidly accumulate in the ischemic gut to exacerbate tissue injury in an innate manner
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  16. Jun 2026
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    Oat-β-glucan potentiates anti-PD-1 efficacy through Faecalibacterium prausnitzii-derived butyrate and indole-3-propionic acid
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    VEGF-C-mediated cardiac lymphangiogenesis promotes inflammation resolution in autoimmune acute myocarditis in mice
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    Whole-genome doubling drives immune evasion by silencing antigen presentation
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    The circadian gene Dec2 promotes pancreatic cancer progression and dormancy through immune evasion
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  23. Apr 2026
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    Nerves Stimulate Cross-talk Between Gastric Cancer and Group 3 Innate Lymphoid Cells to Enhance Immunosuppression
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    Pan-cancer macrophage atlas uncovers that MHC-IIhigh TAMs induce Treg activation through physical interactions
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    Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma
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  27. Mar 2026
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    Reconstruction of T cell infiltration in an osteosarcoma PDX-organoid interactive biobank for personalized immunotherapy
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    Therapeutic Effect of Gemcitabine Combined With Angelica Polysaccharide on Triple Negative Breast Cancer in Mice
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    Chemotherapy triggers immune evasion by fostering LEPR+ Kupffer cell differentiation in liver metastases
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  34. Jan 2026
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    Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells
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    Armored macrophage-targeted CAR-T cells reset and reprogram the tumor microenvironment and control metastatic cancer growth
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    CCL5 deficiency aggravates acute DSS-induced colitis by restricting IL-33-induced formation of Tregs in intestinal tract
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  41. Dec 2025
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    Hepatic adaptation to chronic metabolic stress primes tumorigenesis
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  44. Nov 2025
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  51. Sep 2025
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    Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis
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  54. Aug 2025
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  58. Jul 2025
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    Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer
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  63. Jun 2025
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    BRAF/MEK inhibition induces cell state transitions boosting immune checkpoint sensitivity in BRAFV600E-mutant glioma
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  67. Apr 2025
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    The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy
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    Trabectedin Enhances the Antitumor Effects of IL-12 in Triple-Negative Breast Cancer
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  71. Feb 2025
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    Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease
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    The balance between IFN-γ and ERK/MAPK signaling activities ensures lifelong maintenance of intestinal stem cells
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  75. Jan 2025
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    Negative regulation of lymphangiogenesis by Tenascin-C delays the resolution of inflammation
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    Complement Factor H Is an ICOS Ligand Modulating Tregs in the Glioma Microenvironment
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  79. Dec 2024
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    EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
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  82. Nov 2024
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    JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia
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  85. Oct 2024
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    Microarray analysis of signalling interactions between inflammation and angiogenesis in subchondral bone in temporomandibular joint osteoarthritis
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  87. Sep 2024
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    SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation
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    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
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  90. Jul 2024
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    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
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  93. Jun 2024
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    Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
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  95. May 2024
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    Ablation of Atp5if1 impairs metabolic reprogramming and proliferation of T lymphocytes and compromises mouse survival
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  97. Apr 2024
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    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
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  99. Mar 2024
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    Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells
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    A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer
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  102. Feb 2024
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    Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
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  105. Jan 2024
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    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
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    AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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  109. Nov 2023
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    Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer
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  111. Sep 2023
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    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
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    Select symbionts drive high IgA levels in the mouse intestine
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  114. Aug 2023
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    Lymphatic endothelial transcription factor Tbx1 promotes an immunosuppressive microenvironment to facilitate post-myocardial infarction repair
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  116. Jul 2023
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    Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy
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  118. May 2023
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  121. Apr 2023
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