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Bap1-mediated deubiquitination determines immune tolerance and anti-tumor immunity via modulating eTreg cell differentiation and ferroptosis

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1. scibot 20 Aug 2026
  
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  DOI: 10.1038/s41418-026-01846-y
  
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nature.com/articles/s41418-026-01846-y
Jul 2026
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Efficient generation of human cDC1-like cells to detect and enhance tumor-reactive T cells via CD4+ T cell help

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1. scibot 23 Jul 2026
  
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  DOI: 10.1016/j.crmeth.2026.101533
  
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sciencedirect.com/science/article/pii/S2667237526002341
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RNA exonuclease REXO4 resolves m6A-marked R-loops and suppresses anti-tumor immunity

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1. scibot 21 Jul 2026
  
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  DOI: 10.1016/j.molcel.2026.06.036
  
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METTL14 Enhances Anti-Tumor Immunity through m6A-dependent loss of PD-1

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-0065
  
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aacrjournals.org/cancerres/article/85/21/4151/766750/METTL14-Enhances-Antitumor-Immunity-through-m6A
Jun 2026
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Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance

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  DOI: 10.1016/j.cell.2026.05.036
  
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sciencedirect.com/science/article/pii/S0092867426006367
May 2026
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Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression

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  DOI: 10.1016/j.celrep.2026.117324
  
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mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

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1. scibot 06 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102706
  
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Apr 2026
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STAT5 activation enhances adoptive therapy combined with peptide vaccination by preventing PD-1 inhibition

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  DOI: 10.1158/1535-7163.MCT-24-0505
  
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aacrjournals.org/mct/article/24/3/419/752080/STAT5-Activation-Enhances-Adoptive-Therapy
Mar 2026
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Krüppel-like factors 2 and 3 regulate T cell exhaustion by directing T cell residency and migration

1
1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.021
  
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Comprehensive single-cell metabolic profiling identifies targets to sensitize triple-negative breast cancer to chemo-immunotherapy

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102659
  
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sciencedirect.com/science/article/pii/S2666379126000765
Feb 2026
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Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC class I-deficient solid tumors

1
1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.117035
  
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Hormonal rewiring of immunity during dietary restriction ensures host defense and systemic glucose conservation

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.003
  
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sciencedirect.com/science/article/pii/S1074761326000026
Jan 2026
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5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation

1
1. scibot 05 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102537
  
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sciencedirect.com/science/article/pii/S266637912500610X
Dec 2025
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Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102480
  
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Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy

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1. scibot 03 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.10.015
  
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sciencedirect.com:5037/science/article/pii/S1550413125004759
Nov 2025
54.241.53.176 54.241.53.176

2025.11.06.687030v2.full-html.html

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1. scibot 13 Nov 2025
  
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  DOI: 10.1101/2025.11.06.687030
  
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54.241.53.176/61ff3c01c4fabc7d4036cd8525cf0aefcb431dbf/2025.11.06.687030v2.full-html.html
Sep 2025
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HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer

1
1. scibot 24 Sep 2025
  
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  DOI: 10.1016/j.cmet.2025.08.009
  
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sciencedirect.com/science/article/pii/S1550413125003821
Aug 2025
jeccr.biomedcentral.com jeccr.biomedcentral.com

TRIM6 ablation reverses ICB resistance in MSS gastric cancer by unleashing cGAS-STING-dependent antitumor immunity

1
1. scibot 19 Aug 2025
  
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  DOI: 10.1186/s13046-025-03513-5
  
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jeccr.biomedcentral.com/articles/10.1186/s13046-025-03513-5
Jun 2025
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Bile acids activate cancer-associated fibroblasts and induce an immunosuppressive microenvironment in cholangiocarcinoma

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.ccell.2025.05.017
  
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sciencedirect.com/science/article/pii/S1535610825002260
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A first-in-class EGFR-directed KRAS G12V selective inhibitor

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  DOI: 10.1016/j.ccell.2025.05.016
  
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May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

1
1. scibot 29 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.030
  
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Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

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  DOI: 10.1016/j.cell.2025.04.032
  
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Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.028
  
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Apr 2025
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Epigenomic regulation of stemness contributes to the low immunogenicity of the most mutated human cancer

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  DOI: 10.1016/j.celrep.2025.115561
  
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Albumin-targeted oxaliplatin(iv) prodrugs bearing STING agonists

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1. scibot 08 Apr 2025
  
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  DOI: 10.1039/d5qi00433k
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11969438/
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Albumin-targeted oxaliplatin( iv ) prodrugs bearing STING agonists

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  DOI: 10.1039/D5QI00433K
  
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Mar 2025
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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.devcel.2025.02.016
  
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PDF-html.html

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  DOI: 10.1101/2025.03.19.643961
  
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Feb 2025
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AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.011
  
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1-s2.0-S2589004225003037-main-html.html

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52.53.155.43/3dd3cafa6eaa243b57db8603cc2d3fd3d1e8448b/1-s2.0-S2589004225003037-main-html.html
Dec 2024
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can-24-1611-html.html

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1. scibot 19 Dec 2024
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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52.53.155.43/75f09a51d2e08f557660a3e31ff8f3f3198b5c01/can-24-1611-html.html
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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.11.008
  
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Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

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  DOI: 10.1016/j.celrep.2024.115015
  
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Nov 2024
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A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.devcel.2024.10.010
  
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Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MerTK+ macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation

1
1. scibot 08 Oct 2024
  
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  DOI: 10.1126/sciadv.ado8366
  
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Targeting of CD40 and PD-L1 pathways inhibit progression of oral premalignant lesions in a carcinogen-induced model of oral squamous cell carcinoma

1
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  DOI: 10.1158/1940-6207.CAPR-20-0418
  
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Macrophage-mediated myelin recycling fuels brain cancer malignancy

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  RRID:AB_2687032
  
  DOI: 10.1016/j.cell.2024.07.030
  
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Sep 2024
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Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer

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  RRID:AB_2687032
  
  DOI: 10.1016/j.ccell.2024.08.019
  
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H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114686
  
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Aug 2024
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Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1186/s13046-024-03124-6
  
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Jul 2024
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CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A

1
1. scibot 30 Jul 2024
  
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  RRID:AB_2687032
  
  DOI: 10.1007/s00018-024-05285-1
  
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Apr 2024
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Selective refueling of CAR T cells using ADA1 and CD26 boosts antitumor immunity

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1. scibot 30 Apr 2024
  
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  RRID:AB_2687032
  
  DOI: 10.1016/j.xcrm.2024.101530
  
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Feb 2024
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Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity

2
1. scibot 21 Feb 2024
  
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  RRID:AB_2687032
  
  DOI: 10.1016/j.celrep.2024.113796
  
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  RRID:AB_2687032
  
  DOI: 10.1016/j.celrep.2024.113796
  
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Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

1
1. scibot 16 Feb 2024
  
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  RRID:AB_2687032
  
  DOI: 10.1016/j.celrep.2024.113797
  
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Oct 2023
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Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity

1
1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113211
  
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Sep 2023
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BCG administration promotes the long-term protection afforded by a single-dose intranasal adenovirus-based SARS-CoV-2 vaccine

1
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  DOI: 10.1016/j.isci.2023.107612
  
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May 2023
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CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer

1
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  DOI: 10.1016/j.medj.2023.04.008
  
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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

1
1. scibot 11 May 2023
  
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  RRID:AB_2687032
  
  DOI: 10.1016/j.celrep.2023.112475
  
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BCG administration promotes the long-term protection afforded by a single-dose intranasal adenovirus-based SARS-CoV-2 vaccine

1
1. scibot 05 May 2023
  
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  DOI: 10.1101/2023.03.21.533720
  
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biorxiv.org/content/10.1101/2023.03.21.533720v1
Feb 2023
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HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy

1
1. scibot 17 Feb 2023
  
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  RRID:AB_2687032
  
  DOI: 10.1158/2326-6066.CIR-22-0277
  
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aacrjournals.org/cancerimmunolres/article/11/2/228/716209/HRS-Regulates-Small-Extracellular-Vesicle-PD-L1
Oct 2022
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Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy

1
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  RRID:AB_2687032
  
  DOI: 10.1016/j.cmet.2022.09.021
  
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Oct 2021
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Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

1
1. scibot 06 Oct 2021
  
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  RRID:AB_2687032
  
  DOI: 10.1016/j.immuni.2021.09.002
  
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Sep 2020
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Small Molecule Inhibition of GSK-3 Specifically Inhibits the Transcription of Inhibitory Co-receptor LAG-3 for Enhanced Anti-tumor Immunity

1
1. scibot 10 Sep 2020
  
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  RRID:AB_2687032
  
  DOI: 10.1016/j.celrep.2020.01.076
  
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Jan 2020
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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

1
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  RRID:AB_2687032
  
  DOI: 10.1016/j.cell.2019.07.044
  
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