44 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Deep learning-enhanced R-loop prediction provides mechanistic implications for repeat expansion diseases
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    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.isci.2024.110584

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    sciencedirect.com/science/article/pii/S2589004224018091
  3. Feb 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TOP1 and R-loops facilitate transcriptional DSBs at hypertranscribed cancer driver genes
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.isci.2024.109082

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    ncbi.nlm.nih.gov/pmc/articles/PMC10875566/
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    Protocol for detection of in vitro R-loop formation using dot blots
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.xpro.2024.102857

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    sciencedirect.com/science/article/pii/S2666166724000224
  6. Dec 2023
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
    1
    1. scibot 20 Dec 2023
      RRID:AB_2687463

      DOI: 10.1158/0008-5472.CAN-22-2948

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    ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
  8. Jul 2023
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    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112805

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    sciencedirect.com/science/article/pii/S2211124723008161
  10. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of insertions at a DNA double-strand break
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.molcel.2023.06.016

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    sciencedirect.com/science/article/abs/pii/S1097276523004616
  11. May 2023
  12. www.sciencedirect.com www.sciencedirect.com
    EWSR1 maintains centromere identity
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.celrep.2023.112568

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    sciencedirect.com/science/article/pii/S221112472300579X
  13. www.science.org www.science.org
    Phase separation of HRLP regulates flowering time in Arabidopsis
    1
    1. scibot 05 May 2023
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      DOI: 10.1126/sciadv.abn5488

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    science.org/doi/10.1126/sciadv.abn5488
  14. Feb 2023
  15. www.sciencedirect.com www.sciencedirect.com
    RNA-DNA hybrids prevent resection at dysfunctional telomeres
    1
    1. scibot 02 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112077

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    sciencedirect.com/science/article/pii/S2211124723000888
  16. Jan 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.isci.2022.105784

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    ncbi.nlm.nih.gov/pmc/articles/PMC9800341/
  18. Oct 2022
  19. www.sciencedirect.com www.sciencedirect.com
    RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
    1
    1. scibot 20 Oct 2022
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      DOI: 10.1016/j.molcel.2022.09.025

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    sciencedirect.com/science/article/pii/S1097276522009352
  20. Sep 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Regulation of Claspin by the p38 stress-activated protein kinase protects cells from DNA damage
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111375

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    sciencedirect.com/science/article/pii/S2211124722012074
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS
    1
    1. scibot 02 Sep 2022
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      DOI: 10.1158/0008-5472.CAN-21-1843

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    ncbi.nlm.nih.gov/pmc/articles/PMC7612475/
  23. Jul 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Sen1 is a key regulator of transcription-driven conflicts
    1
    1. scibot 15 Jul 2022
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      DOI: 10.1016/j.molcel.2022.06.021

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    sciencedirect.com/science/article/pii/S1097276522006049
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase separation of HRLP regulates flowering time in Arabidopsis
    1
    1. scibot 09 Jul 2022
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      DOI: 10.1126/sciadv.abn5488

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    ncbi.nlm.nih.gov/pmc/articles/PMC9217094/
  26. May 2022
  27. www.sciencedirect.com www.sciencedirect.com
    DDX41 is required for cGAS-STING activation against DNA virus infection
    1
    1. scibot 26 May 2022
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      DOI: 10.1016/j.celrep.2022.110856

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    sciencedirect.com/science/article/pii/S2211124722006295
  28. Apr 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Detection of RNA-DNA hybrids by immunostaining in meiotic nuclei of Saccharomyces cerevisiae
    1
    1. scibot 20 Apr 2022
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      DOI: 10.1016/j.xpro.2022.101325

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    sciencedirect.com/science/article/pii/S2666166722002052
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    MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells
    1
    1. scibot 06 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110602

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    sciencedirect.com/science/article/pii/S2211124722003503
  31. Feb 2022
  32. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    1
    1. scibot 18 Feb 2022
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      DOI: 10.1016/j.molcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1097276522000570
  33. Dec 2021
  34. www.sciencedirect.com www.sciencedirect.com
    RNA-DNA hybrids regulate meiotic recombination
    1
    1. scibot 08 Dec 2021
      RRID:AB_2687463

      DOI: 10.1016/j.celrep.2021.110097

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    sciencedirect.com/science/article/pii/S2211124721015916
  35. Nov 2021
  36. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
    1
    1. scibot 24 Nov 2021
      RRID:AB_2687463

      DOI: 10.1158/1535-7163.MCT-21-0089

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    mct.aacrjournals.org/content/20/11/2151
  37. Oct 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer
    1
    1. scibot 28 Oct 2021
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      DOI: 10.3390/cancers13205056

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    ncbi.nlm.nih.gov/pmc/articles/PMC8533980/
  39. www.sciencedirect.com www.sciencedirect.com
    Aberrant RNA methylation triggers recruitment of an alkylation repair complex
    1
    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.molcel.2021.09.024

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    sciencedirect.com/science/article/pii/S1097276521007772
  40. www.sciencedirect.com www.sciencedirect.com
    Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair
    1
    1. scibot 16 Oct 2021
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      DOI: 10.1016/j.neuron.2021.09.040

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    sciencedirect.com/science/article/pii/S0896627321007133
  41. www.sciencedirect.com www.sciencedirect.com
    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
    1
    1. scibot 08 Oct 2021
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      DOI: 10.1016/j.molcel.2021.09.016

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    sciencedirect.com/science/article/pii/S1097276521007504
  42. Aug 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination
    1
    1. scibot 27 Aug 2021
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      DOI: 10.1016/j.molcel.2021.07.037

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    sciencedirect.com/science/article/pii/S1097276521006158
  44. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
    1
    1. scibot 01 Aug 2021
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      DOI: 10.1016/j.molcel.2018.04.023

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    sciencedirect.com/science/article/pii/S1097276518303459
  45. Jul 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
    1
    1. scibot 09 Jul 2021
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      DOI: 10.1016/j.molcel.2021.06.016

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    sciencedirect.com/science/article/pii/S1097276521004962
  47. Feb 2021
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The integrated stress response induces R-loops and hinders replication fork progression
    1
    1. scibot 26 Feb 2021
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      DOI: 10.1038/s41419-020-2727-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC7366693/
  49. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
    1
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      DOI: 10.1016/j.celrep.2020.01.020

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    sciencedirect.com/science/article/pii/S2211124720300292
  50. Sep 2020
  51. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
    1
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      DOI: 10.1016/j.celrep.2020.108179

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    pubmed.ncbi.nlm.nih.gov/32966779/
  52. elifesciences.org elifesciences.org
    Transposase-assisted tagmentation of RNA/DNA hybrid duplexes
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      DOI: 10.7554/eLife.54919

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    elifesciences.org/articles/54919
  53. www.sciencedirect.com www.sciencedirect.com
    Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
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      DOI: 10.1016/j.molcel.2020.01.008

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    sciencedirect.com/science/article/pii/S1097276520300083
  54. www.sciencedirect.com www.sciencedirect.com
    Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability
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      DOI: 10.1016/j.celrep.2020.01.087

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    sciencedirect.com/science/article/pii/S2211124720301212
  55. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
    1
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      DOI: 10.1016/j.celrep.2020.01.020

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    sciencedirect.com/science/article/pii/S2211124720300292
  56. Jan 2020
  57. www.sciencedirect.com www.sciencedirect.com
    RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids
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      DOI: 10.1016/j.celrep.2019.10.108

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    sciencedirect.com/science/article/pii/S221112471931441X
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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      DOI: 10.1016/j.molcel.2019.10.026

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    sciencedirect.com/science/article/pii/S1097276519308044
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    Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming
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      DOI: 10.1016/j.stem.2019.08.005

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    sciencedirect.com/science/article/pii/S1934590919303406
  60. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.molcel.2018.11.036

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    sciencedirect.com/science/article/pii/S1097276518310062
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    Untitled document
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      DOI: 10.1016/j.celrep.2018.12.084

      Resource: (Kerafast Cat# ENH001, RRID:AB_2687463)

      Curator: @evieth

      SciCrunch record: RRID:AB_2687463

      What is this?

      RRID:AB_2687463 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718320448
  62. Nov 2018
  63. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687463

      Resource used:

      (Kerafast Cat# ENH001, RRID:AB_2687463)

      SciCrunch record: RRID:AB_2687463

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2687463
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    sciencedirect.com/science/article/pii/S1097276518303459
  64. www.sciencedirect.com www.sciencedirect.com
    The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687463

      Curator: @Jmenke

      Resource used:

      (Kerafast Cat# ENH001, RRID:AB_2687463)

      SciCrunch record: RRID:AB_2687463

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2687463 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517310080
  65. Nov 2017
  66. www.sciencedirect.com www.sciencedirect.com
    Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair
    1
    1. scibot 08 Nov 2017
      ENH001

      Curator: @Jmenke

      Resource used:

      (Kerafast Cat# ENH001, RRID:AB_2687463)

      SciCrunch record: RRID:AB_2687463

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2687463 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416313824
  67. www.sciencedirect.com www.sciencedirect.com
    Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle
    1
    1. scibot 08 Nov 2017
      Mouse monoclonal S9.6 anti-RNA-DNA hybridKerafastCat#ENH001

      Curator: @Jmenke

      Resource used:

      (Kerafast Cat# ENH001, RRID:AB_2687463)

      SciCrunch record: RRID:AB_2687463

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2687463 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867417306475