46 Matching Annotations
  1. Last 7 days
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    Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A
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    sciencedirect.com/science/article/pii/S1097276524009894
  3. Sep 2024
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    Molecular basis of CX-5461-induced DNA damage response in primary vascular smooth muscle cells
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    sciencedirect.com/science/article/pii/S2405844024132586
  5. Aug 2024
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    Deep learning-enhanced R-loop prediction provides mechanistic implications for repeat expansion diseases
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    sciencedirect.com/science/article/pii/S2589004224018091
  7. Feb 2024
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    TOP1 and R-loops facilitate transcriptional DSBs at hypertranscribed cancer driver genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875566/
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    Protocol for detection of in vitro R-loop formation using dot blots
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    sciencedirect.com/science/article/pii/S2666166724000224
  10. Dec 2023
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    1. scibot 20 Dec 2023
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      DOI: 10.1158/0008-5472.CAN-22-2948

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    ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
  12. Jul 2023
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    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
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    sciencedirect.com/science/article/pii/S2211124723008161
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    Mechanisms of insertions at a DNA double-strand break
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    sciencedirect.com/science/article/abs/pii/S1097276523004616
  15. May 2023
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    EWSR1 maintains centromere identity
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    Phase separation of HRLP regulates flowering time in Arabidopsis
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      DOI: 10.1126/sciadv.abn5488

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  18. Feb 2023
  19. www.sciencedirect.com www.sciencedirect.com
    RNA-DNA hybrids prevent resection at dysfunctional telomeres
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    sciencedirect.com/science/article/pii/S2211124723000888
  20. Jan 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate
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    ncbi.nlm.nih.gov/pmc/articles/PMC9800341/
  22. Oct 2022
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    RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
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    sciencedirect.com/science/article/pii/S1097276522009352
  24. Sep 2022
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    Regulation of Claspin by the p38 stress-activated protein kinase protects cells from DNA damage
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  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS
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    ncbi.nlm.nih.gov/pmc/articles/PMC7612475/
  27. Jul 2022
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    Sen1 is a key regulator of transcription-driven conflicts
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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase separation of HRLP regulates flowering time in Arabidopsis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9217094/
  30. May 2022
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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    sciencedirect.com/science/article/pii/S2211124722006295
  32. Apr 2022
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    Detection of RNA-DNA hybrids by immunostaining in meiotic nuclei of Saccharomyces cerevisiae
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    sciencedirect.com/science/article/pii/S2666166722002052
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    MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells
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    sciencedirect.com/science/article/pii/S2211124722003503
  35. Feb 2022
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    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
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    sciencedirect.com/science/article/pii/S1097276522000570
  37. Dec 2021
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    RNA-DNA hybrids regulate meiotic recombination
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    sciencedirect.com/science/article/pii/S2211124721015916
  39. Nov 2021
  40. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
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      DOI: 10.1158/1535-7163.MCT-21-0089

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  41. Oct 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer
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      DOI: 10.3390/cancers13205056

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    ncbi.nlm.nih.gov/pmc/articles/PMC8533980/
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    Aberrant RNA methylation triggers recruitment of an alkylation repair complex
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    sciencedirect.com/science/article/pii/S1097276521007772
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    Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair
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      DOI: 10.1016/j.neuron.2021.09.040

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    sciencedirect.com/science/article/pii/S0896627321007133
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    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
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    sciencedirect.com/science/article/pii/S1097276521007504
  46. Aug 2021
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    Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination
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    sciencedirect.com/science/article/pii/S1097276521006158
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    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
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    sciencedirect.com/science/article/pii/S1097276518303459
  49. Jul 2021
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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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    sciencedirect.com/science/article/pii/S1097276521004962
  51. Feb 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The integrated stress response induces R-loops and hinders replication fork progression
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      DOI: 10.1038/s41419-020-2727-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC7366693/
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    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
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    sciencedirect.com/science/article/pii/S2211124720300292
  54. Sep 2020
  55. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
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    pubmed.ncbi.nlm.nih.gov/32966779/
  56. elifesciences.org elifesciences.org
    Transposase-assisted tagmentation of RNA/DNA hybrid duplexes
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      DOI: 10.7554/eLife.54919

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    elifesciences.org/articles/54919
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    Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
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    sciencedirect.com/science/article/pii/S1097276520300083
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    Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability
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      DOI: 10.1016/j.celrep.2020.01.087

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    sciencedirect.com/science/article/pii/S2211124720301212
  59. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
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      DOI: 10.1016/j.celrep.2020.01.020

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    sciencedirect.com/science/article/pii/S2211124720300292
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids
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      DOI: 10.1016/j.celrep.2019.10.108

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    sciencedirect.com/science/article/pii/S221112471931441X
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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      DOI: 10.1016/j.molcel.2019.10.026

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    sciencedirect.com/science/article/pii/S1097276519308044
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    Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming
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    1. scibot 13 Jan 2020
      RRID:AB_2687463

      DOI: 10.1016/j.stem.2019.08.005

      Resource: (Kerafast Cat# ENH001, RRID:AB_2687463)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2687463

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      RRID:AB_2687463 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590919303406
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    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2687463

      DOI: 10.1016/j.molcel.2018.11.036

      Resource: (Kerafast Cat# ENH001, RRID:AB_2687463)

      Curator: @evieth

      SciCrunch record: RRID:AB_2687463

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      RRID:AB_2687463 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518310062
  65. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2687463

      DOI: 10.1016/j.celrep.2018.12.084

      Resource: (Kerafast Cat# ENH001, RRID:AB_2687463)

      Curator: @evieth

      SciCrunch record: RRID:AB_2687463

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      RRID:AB_2687463 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718320448
  66. Nov 2018
  67. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687463

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      (Kerafast Cat# ENH001, RRID:AB_2687463)

      SciCrunch record: RRID:AB_2687463

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2687463
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    sciencedirect.com/science/article/pii/S1097276518303459
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    The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687463

      Curator: @Jmenke

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      (Kerafast Cat# ENH001, RRID:AB_2687463)

      SciCrunch record: RRID:AB_2687463

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2687463 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517310080
  69. Nov 2017
  70. www.sciencedirect.com www.sciencedirect.com
    Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair
    1
    1. scibot 08 Nov 2017
      ENH001

      Curator: @Jmenke

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      (Kerafast Cat# ENH001, RRID:AB_2687463)

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      RRID:AB_2687463 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416313824
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    Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle
    1
    1. scibot 08 Nov 2017
      Mouse monoclonal S9.6 anti-RNA-DNA hybridKerafastCat#ENH001

      Curator: @Jmenke

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      (Kerafast Cat# ENH001, RRID:AB_2687463)

      SciCrunch record: RRID:AB_2687463

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2687463 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867417306475