18 Matching Annotations
  1. Last 7 days
  2. www.cell.com www.cell.com
    The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
    1
    1. scibot 29 Dec 2024
      RRID:AB_2687562

      DOI: 10.1016/j.cub.2024.11.035

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    cell.com/current-biology/abstract/S0960-9822(24)01575-6
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks
    1
    1. scibot 22 Jun 2024
      RRID:AB_2687562

      DOI: 10.1083/jcb.202402144

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    ncbi.nlm.nih.gov/pmc/articles/PMC11169917/
  5. Apr 2024
  6. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
    2
    1. scibot 25 Apr 2024
      RRID:AB_2687562

      DOI: 10.1083/jcb.202303141

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    2. scibot 25 Apr 2024
      RRID:AB_2687562

      DOI: 10.1083/jcb.202303141

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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
  7. www.sciencedirect.com www.sciencedirect.com
    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
    2
    1. scibot 09 Apr 2024
      RRID:AB_2687562

      DOI: 10.1016/j.celrep.2024.114064

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    2. scibot 09 Apr 2024
      RRID:AB_2687562

      DOI: 10.1016/j.celrep.2024.114064

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    sciencedirect.com/science/article/pii/S2211124724003929
  8. Jun 2023
  9. www.sciencedirect.com www.sciencedirect.com
    PTBP1 enforces ATR-CHK1 signalling determining the potency of CDC7 inhibitors
    1
    1. scibot 09 Jun 2023
      RRID:AB_2687562

      DOI: 10.1016/j.isci.2023.106951

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    sciencedirect.com/science/article/pii/S2589004223010283
  10. Jun 2022
  11. www.sciencedirect.com www.sciencedirect.com
    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
    1
    1. scibot 17 Jun 2022
      RRID:AB_2687562

      DOI: 10.1016/j.isci.2022.104536

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    sciencedirect.com/science/article/pii/S2589004222008070
  12. Apr 2022
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress
    1
    1. scibot 05 Apr 2022
      RRID:AB_2687562

      DOI: 10.1038/s41598-022-09308-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC8971416/
  14. Aug 2021
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53
    1
    1. scibot 05 Aug 2021
      RRID:AB_2687562

      DOI: 10.7554/eLife.70429

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    ncbi.nlm.nih.gov/pmc/articles/PMC8321552/
  16. Jul 2021
  17. www.sciencedirect.com www.sciencedirect.com
    An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells
    1
    1. scibot 23 Jul 2021
      RRID:AB_2687562

      DOI: 10.1016/j.xpro.2021.100677

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    sciencedirect.com/science/article/pii/S2666166721003841
  18. May 2021
  19. www.sciencedirect.com www.sciencedirect.com
    TopBP1 assembles nuclear condensates to switch on ATR signaling
    1
    1. scibot 08 May 2021
      RRID:AB_2687562

      DOI: 10.1016/j.molcel.2020.12.049

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    sciencedirect.com/science/article/pii/S1097276520309916
  20. Apr 2021
  21. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity
    1
    1. scibot 29 Apr 2021
      RRID:AB_2687562

      DOI: 10.1016/j.cmet.2020.07.001

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    sciencedirect.com/science/article/pii/S1550413120303594
  22. Sep 2020
  23. www.sciencedirect.com www.sciencedirect.com
    ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition
    1
    1. scibot 17 Sep 2020
      RRID:AB_2687562

      DOI: 10.1016/j.celrep.2020.108096

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      RRIDCUR:Validated RRID:AB_2687562
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    sciencedirect.com/science/article/pii/S2211124720310858
  24. Jan 2020
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687562

      DOI: 10.7554/eLife.44353

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      Curator: @evieth

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      RRID:AB_2687562 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
  26. www.sciencedirect.com www.sciencedirect.com
    Preclinical study using androgen receptor (AR) degradation enhancer to increase radiotherapy efficacy via targeting radiation-increased AR to better suppress prostate cancer progression
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687562

      DOI: 10.1016/j.ebiom.2018.12.050

      Resource: (GeneTex Cat# GTX128145, RRID:AB_2687562)

      Curator: @ethanbadger

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      RRID:AB_2687562 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2352396418306273
  27. Nov 2018
  28. www.sciencedirect.com www.sciencedirect.com
    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687562

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      (GeneTex Cat# GTX128145, RRID:AB_2687562)

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    sciencedirect.com/science/article/pii/S1535610818302691
  29. Nov 2017
  30. www.sciencedirect.com www.sciencedirect.com
    A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
    1
    1. scibot 08 Nov 2017
      Rabbit polyclonal anti-phospho-ATR (T1989)GeneTexCat#GTX128145

      Curator: @Jmenke

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      (GeneTex Cat# GTX128145, RRID:AB_2687562)

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      RRID:AB_2687562 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867417305378