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arroyo-gomez-et-al-2025-functional-landscape-of-ubiquitin-linkages-couples-k29-linked-ubiquitylation-to-epigenome-html.html

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1. scibot 30 Oct 2025
  
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  DOI: 10.1038/s44318-025-00599-7
  
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54.241.53.176/9315414eccf1e15b040c95d437c7e801ecba4152/arroyo-gomez-et-al-2025-functional-landscape-of-ubiquitin-linkages-couples-k29-linked-ubiquitylation-to-epigenome-html.html
Jul 2025
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Chromosomal tethering and mitotic transcription promote ecDNA nuclear inheritance

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1. scibot 03 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.06.013
  
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sciencedirect.com/science/article/pii/S1097276525005428
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells

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1. scibot 01 Jul 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0058
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12202856/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bromodomain and Extra-Terminal Family Proteins BRD2, BRD3, and BRD4 Contribute to H19-Dependent Transcriptional Regulation of Cell Adhesion Molecules, Modulating Metastatic Dissemination Program in Prostate Cancer

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1. scibot 12 Jun 2025
  
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  DOI: 10.3390/ncrna11030033
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12101203/
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 12 Jun 2025
  
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  DOI: 10.1158/2767-9764.crc-25-0058
  
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52.53.155.43/6f95ee3860ed32eb2fc3447b03e264cd8239544f/PDF-html.html
Mar 2025
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BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.101995
  
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sciencedirect.com/science/article/pii/S2666379125000680
Dec 2024
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TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.007
  
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sciencedirect.com/science/article/pii/S1097276524009122
Aug 2024
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Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies

1
1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.chembiol.2024.07.005
  
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sciencedirect.com/science/article/pii/S2451945624003076
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The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1186/s12885-024-12691-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11292958/
Jul 2024
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Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance

1
1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.012
  
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sciencedirect.com/science/article/pii/S0092867424006524
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Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114431
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology

1
1. scibot 27 Jun 2024
  
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  DOI: 10.1016/j.xpro.2024.103129
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11193044/
May 2024
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Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma

1
1. scibot 09 May 2024
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.celrep.2024.114211
  
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sciencedirect.com/science/article/pii/S2211124724005394
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

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1. scibot 24 Apr 2024
  
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  DOI: 10.1093/narcan/zcae018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
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STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma

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1. scibot 03 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101472
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
Feb 2024
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A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis

1
1. scibot 29 Feb 2024
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.molcel.2024.02.002
  
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sciencedirect.com/science/article/pii/S1097276524000984
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Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting

1
1. scibot 21 Feb 2024
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.molcel.2024.01.022
  
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sciencedirect.com/science/article/pii/S1097276524000893
www.biorxiv.org www.biorxiv.org

HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

3
1. scibot 09 Feb 2024
  
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  RRID:AB_2687578
  
  DOI: 10.1101/2023.12.05.570182
  
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2. scibot 09 Feb 2024
  
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  RRID:AB_2687578
  
  DOI: 10.1101/2023.12.05.570182
  
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  RRID:AB_2687578
  
  DOI: 10.1101/2023.12.05.570182
  
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biorxiv.org/content/10.1101/2023.12.05.570182v1
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The cyclimids: Degron-inspired cereblon binders for targeted protein degradation

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1. scibot 06 Feb 2024
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.chembiol.2024.01.003
  
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sciencedirect.com/science/article/pii/S2451945624000394
Nov 2023
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Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.chembiol.2023.10.005
  
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sciencedirect.com/science/article/pii/S2451945623003665
Oct 2023
52.53.155.43 52.53.155.43

PIIS0092867423009650-html.html

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1. scibot 06 Oct 2023
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.cell.2023.08.032
  
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52.53.155.43/10a4fc8c2567a3934d6a2c0730d82b14865b6e30/PIIS0092867423009650-html.html
Jul 2023
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Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation

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1. scibot 13 Jul 2023
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.molcel.2023.06.032
  
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sciencedirect.com/science/article/abs/pii/S1097276523005087
Apr 2023
www.science.org www.science.org

Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis

2
1. scibot 20 Apr 2023
  
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  DOI: 10.1126/sciadv.ade3422
  
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2. scibot 14 Apr 2023
  
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  DOI: 10.1126/sciadv.ade3422
  
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science.org/doi/10.1126/sciadv.ade3422
Feb 2023
aacrjournals.org aacrjournals.org

Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells

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1. scibot 18 Feb 2023
  
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  RRID: AB_2687578
  
  DOI: 10.1158/1541-7786.MCR-21-1000
  
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aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cloning BRD4 long isoform into overexpression vectors for stable overexpression of BRD4-L in mammalian cells

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1. scibot 02 Nov 2022
  
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  DOI: 10.1016/j.xpro.2022.101785
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9617197/
Sep 2022
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BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer

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1. scibot 15 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111304
  
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sciencedirect.com/science/article/pii/S2211124722011287
Jun 2022
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A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader

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1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.chembiol.2022.05.003
  
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sciencedirect.com/science/article/pii/S2451945622001659
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases

1
1. scibot 18 Mar 2022
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.isci.2022.103985
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
Feb 2022
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The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation

1
1. scibot 23 Feb 2022
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.molcel.2022.01.024
  
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sciencedirect.com/science/article/pii/S1097276522001009
Sep 2021
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A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes

1
1. scibot 09 Sep 2021
  
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  DOI: 10.1016/j.chembiol.2021.08.007
  
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sciencedirect.com/science/article/pii/S2451945621003962
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SPT5 stabilization of promoter-proximal RNA polymerase II

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1. scibot 04 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.08.006
  
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sciencedirect.com/science/article/pii/S1097276521006468
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 09 Aug 2021
  
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  DOI: 10.7554/eLife.39023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6279352/
www.nature.com www.nature.com

Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

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1. scibot 05 Aug 2021
  
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  RRID:AB_2687578
  
  DOI: 10.1038/s41467-021-24687-4
  
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nature.com/articles/s41467-021-24687-4
Mar 2021
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TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains

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1. scibot 29 Mar 2021
  
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  RRID:AB_2687578
  
  DOI: 10.1016/j.molcel.2021.01.023
  
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sciencedirect.com/science/article/pii/S1097276521000435
Jan 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Expression and clinical value of PD‐L1 which is regulated by BRD4 in tongue squamous cell carcinoma

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1. scibot 13 Jan 2020
  
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  RRID:AB_2687578
  
  DOI: 10.1002/jcb.29420
  
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onlinelibrary.wiley.com/doi/10.1002/jcb.29420
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2687578
  
  DOI: 10.7554/eLife.41913
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6336405/
Nov 2018
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Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

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1. scibot 05 Nov 2018
  
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  RRID:AB_2687578
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S009286741831239X
www.cell.com www.cell.com

Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2687578
  
  Curator: @Jmenke
  
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cell.com/cell/fulltext/S0092-8674(18)31119-X
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BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

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1. scibot 05 Nov 2018
  
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  RRID:AB_2687578
  
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sciencedirect.com/science/article/pii/S1535610818300199
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic Functional Annotation of Somatic Mutations in Cancer

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1. scibot 05 Nov 2018
  
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  RRID:AB_2687578
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
Nov 2017
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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

1
1. scibot 08 Nov 2017
  
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  Rabbit monoclonal anti-BRD4 (clone E2A7X) (human specific) (long isoform)Cell Signaling TechnologyCat#: 13440S
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S109727651730312X