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  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Differentially Affects Axonal Autophagosome Formation and Maturation
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    1. scibot 20 Jul 2024
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      DOI: 10.1080/15548627.2023.2236485

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    ncbi.nlm.nih.gov/pmc/articles/PMC10621248/
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    scRank infers drug-responsive cell types from untreated scRNA-seq data using a target-perturbed gene regulatory network
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    1. scibot 16 May 2024
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      DOI: 10.1016/j.xcrm.2024.101568

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    sciencedirect.com/science/article/pii/S266637912400260X
  5. Mar 2024
  6. www.sciencedirect.com www.sciencedirect.com
    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
    2
    1. scibot 21 Mar 2024
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      DOI: 10.1016/j.neuron.2024.02.017

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    2. scibot 21 Mar 2024
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      DOI: 10.1016/j.neuron.2024.02.017

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    sciencedirect.com/science/article/pii/S0896627324001272
  7. Feb 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
    3
    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113760

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      DOI: 10.1016/j.celrep.2024.113760

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      DOI: 10.1016/j.celrep.2024.113760

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    sciencedirect.com/science/article/pii/S2211124724000883
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal stress drives the release of pathogenic α-synuclein from macrophage lineage cells via the LRRK2-Rab10 pathway
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    1. scibot 06 Feb 2024
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      DOI: 10.1016/j.isci.2024.108893

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    ncbi.nlm.nih.gov/pmc/articles/PMC10835446/
  10. Jan 2024
  11. www.sciencedirect.com www.sciencedirect.com
    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.015

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    sciencedirect.com/science/article/pii/S1550413123004655
  12. Oct 2023
  13. www.science.org www.science.org
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/sciadv.abo3610

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    science.org/doi/10.1126/sciadv.abo3610
  14. Sep 2023
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of HMGB1/RAGE/cathespin B inhibitors on alleviating hippocampal injury by regulating microglial pyroptosis and caspase activation in neonatal hypoxic–ischemic brain damage
    1
    1. scibot 29 Sep 2023
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      DOI: 10.1111/jnc.15965

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15965
  16. www.embopress.org www.embopress.org
    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
    1
    1. scibot 12 Sep 2023
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      DOI: 10.15252/embr.202356948

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    embopress.org/doi/full/10.15252/embr.202356948
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    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
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    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.devcel.2023.08.013

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    sciencedirect.com/science/article/pii/S1534580723004094
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    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
    1
    1. scibot 01 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113042

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    sciencedirect.com/science/article/pii/S2211124723010537
  19. Apr 2023
  20. www.science.org www.science.org
    An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation
    2
    1. scibot 27 Apr 2023
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      DOI: 10.1126/sciadv.adf8966

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    2. scibot 27 Apr 2023
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      DOI: 10.1126/sciadv.adf8966

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    science.org/doi/10.1126/sciadv.adf8966
  21. Jan 2023
  22. www.sciencedirect.com www.sciencedirect.com
    ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis
    1
    1. scibot 02 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111911

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    sciencedirect.com/science/article/pii/S2211124722018101
  23. Dec 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
    1
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      DOI: 10.1016/j.celrep.2022.111742

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    sciencedirect.com/science/article/pii/S2211124722016205
  25. Oct 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein
    1
    1. scibot 28 Oct 2022
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      DOI: 10.1016/j.chembiol.2022.10.006

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    sciencedirect.com/science/article/pii/S2451945622003609
  27. www.sciencedirect.com www.sciencedirect.com
    Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis
    1
    1. scibot 20 Oct 2022
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      DOI: 10.1016/j.medj.2022.09.007

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    sciencedirect.com/science/article/pii/S2666634022004081
  28. Sep 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
    1
    1. scibot 11 Sep 2022
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      DOI: 10.1016/j.ccell.2022.08.012

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    sciencedirect.com/science/article/pii/S1535610822003762
  30. Aug 2022
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
    2
    1. scibot 13 Aug 2022
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      DOI: 10.1126/sciadv.abo3610

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    2. scibot 13 Aug 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9299535/
  32. Jun 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
    1
    1. scibot 08 Jun 2022
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      DOI: 10.1016/j.molcel.2022.05.009

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    sciencedirect.com/science/article/pii/S1097276522004439
  34. May 2022
  35. journals.sagepub.com journals.sagepub.com
    Cathepsin B Relocalization in Late Membrane Disrupted Neurons Following Diffuse Brain Injury in Rats - Martina L. Hernandez, Michael Marone, Karen M. Gorse, Audrey D. Lafrenaye, 2022
    1
    1. scibot 10 May 2022
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      DOI: 10.1177/17590914221099112

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    journals.sagepub.com/doi/full/10.1177/17590914221099112
  36. Dec 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells
    1
    1. scibot 02 Dec 2021
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      DOI: 10.1158/0008-5472.CAN-20-3371

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    ncbi.nlm.nih.gov/pmc/articles/PMC8178204/
  38. Jul 2021
  39. pubs.acs.org pubs.acs.org
    The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
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    1. scibot 02 Jul 2021
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      DOI: 10.1021/acsinfecdis.0c00349

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    pubs.acs.org/doi/full/10.1021/acsinfecdis.0c00349
  40. Jun 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Oncogene-regulated release of extracellular vesicles
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    1. scibot 12 Jun 2021
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      DOI: 10.1016/j.devcel.2021.05.014

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    sciencedirect.com/science/article/pii/S1534580721004433
  42. Mar 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
    1
    1. scibot 10 Mar 2021
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      DOI: 10.1016/j.celrep.2021.108826

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    sciencedirect.com/science/article/pii/S2211124721001406
  44. Sep 2020
  45. www.sciencedirect.com www.sciencedirect.com
    Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
    1
    1. scibot 11 Sep 2020
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      DOI: 10.1016/j.ccell.2020.03.016

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    sciencedirect.com/science/article/pii/S1535610820301562
  46. Jan 2020
  47. iovs.arvojournals.org iovs.arvojournals.org
    Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal
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    1. scibot 13 Jan 2020
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      DOI: 10.1167/iovs.18-26360

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    iovs.arvojournals.org/article.aspx
  48. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_2687580

      DOI: 10.1016/j.devcel.2019.03.011

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    sciencedirect.com/science/article/pii/S1534580719301881
  49. Nov 2017
  50. www.sciencedirect.com www.sciencedirect.com
    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
    1
    1. scibot 08 Nov 2017
      Rabbit monoclonal anti-Cathepsin B (clone D1C7Y)Cell Signaling TechnologyCat#: 31718S

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    sciencedirect.com/science/article/pii/S109727651730312X