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Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations

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1. scibot 06 Aug 2025
  
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  DOI: 10.1158/2159-8290.CD-24-1259
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319405/
Jul 2025
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Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer

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1. scibot 10 Jul 2025
  
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  DOI: 10.1186/s12964-025-02337-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12235933/
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1-s2.0-S2589004225013215-main-html.html

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113060
  
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52.53.155.43/f7de3ac929f9dcf0b46f3534fc31af712bb2cc52/1-s2.0-S2589004225013215-main-html.html
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MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction

1
1. scibot 03 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.06.005
  
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sciencedirect.com/science/article/pii/S1097276525005052
Jun 2025
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Cingulin is an RNA-binding protein promoting pancreatic cancer through enhancing importin 7-mediated phospho-ERK nuclear translocation

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115925
  
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sciencedirect.com/science/article/pii/S2211124725006965
May 2025
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Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

1
1. scibot 21 May 2025
  
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  DOI: 10.7554/eLife.103615
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12055001/
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1-s2.0-S258900422500879X-main-html.html

2
1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112618
  
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2. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112618
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12152665/
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Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

1
1. scibot 16 May 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2220
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
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Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115627
  
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sciencedirect.com/science/article/pii/S2211124725003985
Apr 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

SRPK1 Activation Facilitates Gli3S664 Phosphorylation and Promotes Metastasis in Esophageal Squamous Cell Carcinoma

1
1. scibot 17 Apr 2025
  
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  DOI: 10.1002/mc.23913
  
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onlinelibrary.wiley.com/doi/full/10.1002/mc.23913
Mar 2025
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ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity

1
1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115361
  
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sciencedirect.com/science/article/pii/S2211124725001329
Feb 2025
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TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion

1
1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115315
  
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sciencedirect.com/science/article/pii/S2211124725000865
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Single-cell and spatial transcriptomics reveal a potential role of ATF3 in brain metastasis of lung adenocarcinoma

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1. scibot 16 Feb 2025
  
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  RRID:AB_2687616
  
  DOI: 10.21037/tlcr-24-784
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11826269/
aacrjournals.org aacrjournals.org

Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-23-3987
  
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aacrjournals.org/cancerres/article/84/20/3371/749080/Cancer-Associated-Fibroblasts-Expressing-Sulfatase
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TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-22-3009
  
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aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
Dec 2024
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P-cadherin mechanoactivates tumor-mesothelium metabolic coupling to promote ovarian cancer metastasis

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1. scibot 19 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115096
  
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sciencedirect.com/science/article/pii/S2211124724014475
Nov 2024
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Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells

1
1. scibot 16 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111269
  
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sciencedirect.com/science/article/pii/S2589004224024945
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CircZNF609/miR-324-5p/VDAC1 axis promotes malignant progression of ovarian cancer cells

1
1. scibot 10 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.110861
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11539587/
Sep 2024
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Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy

1
1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.013
  
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sciencedirect.com/science/article/pii/S0092867424009048
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Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114652
  
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sciencedirect.com/science/article/pii/S2211124724010039
Jul 2024
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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.celrep.2021.109363
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
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Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy

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1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.ebiom.2024.105212
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11261775/
Jun 2024
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DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma

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1. scibot 08 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.109827
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11141150/
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Secretion of WNT7A by UC-MSCs assist in promoting the endometrial epithelial regeneration

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1. scibot 08 Jun 2024
  
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  RRID:AB_2687616
  
  DOI: 10.1016/j.isci.2024.109888
  
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52.53.155.43/cced30d2a74f6a0a443c073a769617b5ff3774c6/1-s2.0-S2589004224011106-main-html.html
May 2024
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Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.ccell.2024.04.012
  
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sciencedirect.com/science/article/pii/S1535610824001363
Apr 2024
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Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling

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1. scibot 16 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101510
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11148513/
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Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.024
  
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sciencedirect.com/science/article/pii/S1534580724001928
Feb 2024
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CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin

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1. scibot 22 Feb 2024
  
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  DOI: 10.1038/s41388-024-02968-8
  
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link.springer.com/article/10.1038/s41388-024-02968-8
Dec 2023
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AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108523
  
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Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113511
  
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sciencedirect.com/science/article/pii/S2211124723015231
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A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas

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1. scibot 20 Dec 2023
  
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  DOI: 10.1186/s40478-023-01677-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10725030/
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Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma

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1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.ccell.2023.11.010
  
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sciencedirect.com/science/article/pii/S1535610823004014
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Hypoxia induces hepatocellular carcinoma metastasis via the HIF-1α/METTL16/lnc-CSMD1-7/RBFOX2 axis

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108495
  
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sciencedirect.com/science/article/pii/S2589004223025725
Oct 2023
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Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113310
  
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Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain

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Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondria

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Fusobacterium nucleatum promotes colorectal cancer metastasis by excretion of miR-122-5p from cells via exosomes

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HOXA11 promotes lymphatic metastasis of gastric cancer via transcriptional activation of TGFβ1

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SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

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Investigating the effects of 7-ketocholesterol on retinal pigment epithelium bioenergetics

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TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis

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KDM4B down-regulation facilitated breast cancer cell stemness via PHGDH upregulation in H3K36me3-dependent manner

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Trigeminal nerve derived-substance P regulates limbal stem cells by the PI3K-AKT pathway

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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study

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Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation

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Controlling human organoid symmetry breaking reveals signaling gradients drive segmentation clock waves

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Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study

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ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

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Generation of human elongating multi-lineage organized cardiac gastruloids

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Hedgehog regulation of epithelial cell state and morphogenesis in the larynx

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The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma

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GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A

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In vivo nanoscopic landscape of neurexin ligands underlying anterograde synapse specification

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Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways

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Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines

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Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis

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A Combined Human Gastruloid Model of Cardiogenesis and Neurogenesis

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Stub1 maintains proteostasis of master transcription factors in embryonic stem cells

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TNFɑ Antagonist in Combination with PD-1 Blocker to Prevent or Retard Malignant Transformation of B[a]P-induced Chronic Lung Inflammation

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academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgac024/6540320
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Cortical reorganization of the glutamate synapse in the activity-based anorexia rat model: impact on cognition

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Delicate regulation of IL-1β-mediated inflammation by cyclophilin A

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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

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Feb 2022
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A positive feed-forward loop between Fusobacterium nucleatum and ethanol metabolism reprogramming drives laryngeal cancer progression and metastasis

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  DOI: 10.1016/j.isci.2022.103829
  
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Radiation induces epithelial to mesenchymal transition via upregulation of PD-L1 in nasopharyngeal carcinoma cell

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ncbi.nlm.nih.gov/pmc/articles/PMC8797608/
Dec 2021
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Translational and post-translational control of human naïve versus primed pluripotency

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Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1

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Nov 2021
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Modulating mesendoderm competence during human germ layer differentiation

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A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation

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MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer

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Kinase DYRK2 acts as a regulator of autophagy and an indicator of favorable prognosis in gastric carcinoma

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The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy

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Untitled document

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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Genomic Function of Estrogen Receptor Beta In Endometriosis

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BPS Publications

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

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Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

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PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR

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Chronic restraint stress promotes the mobilization and recruitment of myeloid-derived suppressor cells through β-adrenergic-activated CXCL5-CXCR2-Erk signaling cascades

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  anti-N-cadherin
  
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Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spines

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Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment

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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

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Alisertib inhibits migration and invasion of EGFR-TKI resistant cells by partially reversing the epithelial-mesenchymal transition

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  N-cadherin
  
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Systematic characterization of mutations altering protein degradation in human cancers

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A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)

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Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure

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Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer

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H1N1 Influenza Virus Cross-Activates Gli1 to Disrupt the Intercellular Junctions of Alveolar Epithelial Cells

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Impairment of pericyte-endothelium crosstalk leads to blood-brain barrier dysfunction following traumatic brain injury

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GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway

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Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation

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Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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ncbi.nlm.nih.gov/pmc/articles/PMC6625753/
Nov 2018
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Directed fusion of cardiac spheroids into larger heterocellular microtissues enables investigation of cardiac action potential propagation via cardiac fibroblasts

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Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

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ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal Transition

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