128 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PD-L1 expression is mediated by microRNA processing, Wnt/β-catenin signaling, and chemotherapy in Wilms tumor
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    1. scibot 21 Dec 2024
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      DOI: 10.1101/2024.11.29.626084

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  3. 52.53.155.43 52.53.155.43
    ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway-html.html
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    1. scibot 19 Dec 2024
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    52.53.155.43/7324a4302b92926502f88e0cd10bf0b0ca3de710/ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway-html.html
  4. Dec 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma
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    1. scibot 02 Dec 2024
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    sciencedirect.com/science/article/pii/S2211124724013664
  6. Nov 2024
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    ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion
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    1. scibot 24 Nov 2024
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    Langerhans cells directly interact with resident T cells in the human epidermis
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    Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer
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  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
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    1. scibot 07 Nov 2024
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      DOI: 10.3389/fonc.2024.1441935

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
  11. Oct 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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  13. Aug 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of Forkhead Box P3 in Interferon γ-mediated PD-L1 Expression and Bladder Cancer Epithelial-to-Mesenchymal Transition
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    1. scibot 28 Aug 2024
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    Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma
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    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S2589004224018297
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statins inhibit paclitaxel-induced PD-L1 expression and increase CD8+ T cytotoxicity for better prognosis in breast cancer
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    1. scibot 22 Aug 2024
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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    "Expression and prognostic relevance of PD-1, PD-L1 and CTLA-4 immune checkpoints in adrenocortical carcinoma"
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    1. scibot 21 Aug 2024
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      DOI: 10.1210/clinem/dgae109

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  18. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells
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    1. scibot 02 Aug 2024
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  19. Jul 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis
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    1. scibot 12 Jul 2024
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  21. www.cell.com www.cell.com
    Cyclin dependent kinase 9 inhibition reduced programmed death-ligand 1 expression and improved treatment efficacy in hepatocellular carcinoma
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.heliyon.2024.e34289

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    cell.com/heliyon/fulltext/S2405-8440(24)10320-9
  22. May 2024
  23. www.sciencedirect.com www.sciencedirect.com
    Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers
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    1. scibot 30 May 2024
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    sciencedirect.com/science/article/pii/S2666379124002817
  24. www.sciencedirect.com www.sciencedirect.com
    Decision model for durable clinical benefit from front- or late-line immunotherapy alone or with chemotherapy in non-small cell lung cancer
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    1. scibot 23 May 2024
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    sciencedirect.com/science/article/pii/S2666634024002046
  25. Apr 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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    1. scibot 03 Apr 2024
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      DOI: 10.1158/1078-0432.CCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  27. Mar 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
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    sciencedirect.com/science/article/pii/S1534580724000765
  29. Feb 2024
  30. aacrjournals.org aacrjournals.org
    Biomarkers of Pathological Complete Response to Neoadjuvant Immunotherapy in Mismatch Repair Deficiency Colorectal Cancer
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    1. scibot 24 Feb 2024
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      DOI: 10.1158/1078-0432.CCR-23-2213

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    aacrjournals.org/clincancerres/article/30/2/368/733205/Biomarkers-of-Pathologic-Complete-Response-to
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    Genomic characteristics and immune landscape of super multiple primary lung cancer
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    sciencedirect.com/science/article/pii/S2352396424000549
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    Circulating cancer-specific CD8 T cell frequency is associated with response to PD-1 blockade in Merkel cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379124000351
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    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients
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      DOI: 10.1158/1078-0432.CCR-23-0215

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  35. Jan 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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    Benzosceptrin C induces lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting DHHC3
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    sciencedirect.com/science/article/pii/S2666379123005748
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    A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
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    sciencedirect.com/science/article/pii/S0092867423013223
  39. Dec 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma
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  41. 52.53.155.43 52.53.155.43
    ccr-23-2213-html.html
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  42. Nov 2023
  43. www.sciencedirect.com www.sciencedirect.com
    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    sciencedirect.com/science/article/pii/S2211124723014894
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    Efficacy of sequential chemoradiotherapy combined with toripalimab in de novo metastatic nasopharyngeal carcinoma: A phase II trial
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    sciencedirect.com/science/article/pii/S2666379123004731
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    Multi-kingdom gut microbiota analyses define bacterial-fungal interplay and microbial markers of pan-cancer immunotherapy across cohorts
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    sciencedirect.com/science/article/pii/S1931312823004092
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    Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer
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    sciencedirect.com/science/article/pii/S1535610823003628
  47. www.mdpi.com www.mdpi.com
    PD-L1 and HIF-2α Upregulation in Head and Neck Paragangliomas after Embolization
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    1. scibot 03 Nov 2023
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      DOI: 10.3390/cancers15215199

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    mdpi.com/2072-6694/15/21/5199
  48. www.nature.com www.nature.com
    Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma
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      DOI: 10.1038/s41698-023-00434-4

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    nature.com/articles/s41698-023-00434-4
  49. Oct 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
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      DOI: 10.1016/j.celrep.2023.113318

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    sciencedirect.com/science/article/pii/S221112472301330X
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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      DOI: 10.1016/j.molcel.2023.09.007

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    sciencedirect.com/science/article/pii/S1097276523007025
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    Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity
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      DOI: 10.1016/j.celrep.2023.113224

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  53. Sep 2023
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    Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy
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    Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin
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    Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib treatment in patients with BRAF-mutant melanoma brain metastases
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  58. Jul 2023
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    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
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  60. Jun 2023
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    TOPK mediates immune evasion of Renal Cell Carcinoma via upregulating the expression of PD-L1
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  64. May 2023
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    Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer
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    Association of PD-1/PD-L1 Co-location with Immunotherapy Outcomes in Non-Small Cell Lung Cancer
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  68. Apr 2023
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    Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy
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    Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer
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    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
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    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
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  73. Mar 2023
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    Characterization of glycometabolism and tumor immune microenvironment for predicting clinical outcomes in gastric cancer
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  76. Feb 2023
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    HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy
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  78. Jan 2023
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    Cabozantinib plus durvalumab in advanced gastroesophageal cancer and other gastrointestinal malignancies: Phase Ib CAMILLA trial results
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    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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  81. Dec 2022
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    Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts
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    NF-κB-regulated VentX expression mediates tumoricidal effects of chemotherapeutics at noncytotoxic concentrations
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    Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors
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  89. Sep 2022
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    Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy
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    PSEN1 is associated with colon cancer development via potential influences on PD-L1 nuclear translocation and tumor-immune interactions
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  92. Aug 2022
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    Gemcitabine combined with apatinib and toripalimab in recurrent or metastatic nasopharyngeal carcinoma
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity
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  96. Jun 2022
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    NRF2 Serves A Critical Role In Regulation Of Immune Checkpoint Proteins (ICPs) During Trophoblast Differentiation
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    Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model
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    The SETDB1–TRIM28 complex suppresses antitumor immunity
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  100. May 2022
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    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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    Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma
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  104. Mar 2022
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    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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  106. Feb 2022
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    An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer
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    PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
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  131. Jun 2021
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    sciencedirect.com/science/article/pii/S1535610819302995
  160. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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    1. scibot 13 Jan 2020
      AB_2687655

      DOI: 10.1016/j.ccell.2019.10.001

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    sciencedirect.com/science/article/pii/S1535610819304398
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    The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer
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    1. scibot 13 Jan 2020
      RRID:AB_2687655

      DOI: 10.1016/j.celrep.2019.04.098

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    sciencedirect.com/science/article/pii/S2211124719305789
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    Untitled document
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      RRID:AB_2687655

      DOI: 10.1016/j.cell.2019.03.005

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    sciencedirect.com/science/article/pii/S0092867419302673
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    Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy
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      RRID:AB_2687655

      DOI: 10.1016/j.ccell.2019.01.003

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    sciencedirect.com/science/article/pii/S1535610819300376
  164. www.cell.com www.cell.com
    Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
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      DOI: 10.1016/j.cell.2019.02.016

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    cell.com/cell/fulltext/S0092-8674(19)30165-5
  165. Nov 2018
  166. www.sciencedirect.com www.sciencedirect.com
    Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny
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    sciencedirect.com/science/article/pii/S221112471831492X
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    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    sciencedirect.com/science/article/pii/S1097276518305999
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  169. Nov 2017
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    Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
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      13684

      Curator: @Jmenke

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