111 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
    1
    1. scibot 03 Apr 2024
      RRID:AB_2687655

      DOI: 10.1158/1078-0432.CCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.005

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    2. scibot 06 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.005

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    sciencedirect.com/science/article/pii/S1534580724000765
  5. Feb 2024
  6. aacrjournals.org aacrjournals.org
    Biomarkers of Pathological Complete Response to Neoadjuvant Immunotherapy in Mismatch Repair Deficiency Colorectal Cancer
    1
    1. scibot 24 Feb 2024
      RRID:AB_2687655

      DOI: 10.1158/1078-0432.CCR-23-2213

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    aacrjournals.org/clincancerres/article/30/2/368/733205/Biomarkers-of-Pathologic-Complete-Response-to
  7. www.sciencedirect.com www.sciencedirect.com
    Genomic characteristics and immune landscape of super multiple primary lung cancer
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.ebiom.2024.105019

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    sciencedirect.com/science/article/pii/S2352396424000549
  8. www.sciencedirect.com www.sciencedirect.com
    Circulating cancer-specific CD8 T cell frequency is associated with response to PD-1 blockade in Merkel cell carcinoma
    2
    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101412

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    2. scibot 13 Feb 2024
      RRID:AB_2687655

      DOI: 10.1016/j.xcrm.2024.101412

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    sciencedirect.com/science/article/pii/S2666379124000351
  9. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
    1
    1. scibot 06 Feb 2024
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      DOI: 10.1016/j.chembiol.2024.01.002

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    sciencedirect.com/science/article/pii/S2451945624000382
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients
    1
    1. scibot 02 Feb 2024
      RRID:AB_2687655

      DOI: 10.1158/1078-0432.CCR-23-0215

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524955/
  11. Jan 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101374

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    sciencedirect.com/science/article/pii/S2666379123006031
  13. www.sciencedirect.com www.sciencedirect.com
    Benzosceptrin C induces lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting DHHC3
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101357

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    sciencedirect.com/science/article/pii/S2666379123005748
  14. www.sciencedirect.com www.sciencedirect.com
    A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cell.2023.11.037

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    sciencedirect.com/science/article/pii/S0092867423013223
  15. Dec 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.xcrm.2023.101302

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    sciencedirect.com/science/article/pii/S2666379123004962
  17. 52.53.155.43 52.53.155.43
    ccr-23-2213-html.html
    1
    1. scibot 18 Dec 2023
      AB_2687655

      DOI: 10.1158/1078-0432.ccr-23-2213

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    52.53.155.43/771fdcc68e9c690a39fa0e5c39847693279e782c/ccr-23-2213-html.html
  18. Nov 2023
  19. www.sciencedirect.com www.sciencedirect.com
    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
    1
    1. scibot 22 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113477

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    sciencedirect.com/science/article/pii/S2211124723014894
  20. www.sciencedirect.com www.sciencedirect.com
    Efficacy of sequential chemoradiotherapy combined with toripalimab in de novo metastatic nasopharyngeal carcinoma: A phase II trial
    1
    1. scibot 17 Nov 2023
      RRID:AB_2687655

      DOI: 10.1016/j.xcrm.2023.101279

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    sciencedirect.com/science/article/pii/S2666379123004731
  21. www.sciencedirect.com www.sciencedirect.com
    Multi-kingdom gut microbiota analyses define bacterial-fungal interplay and microbial markers of pan-cancer immunotherapy across cohorts
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.chom.2023.10.005

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    sciencedirect.com/science/article/pii/S1931312823004092
  22. www.sciencedirect.com www.sciencedirect.com
    Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.ccell.2023.10.006

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    sciencedirect.com/science/article/pii/S1535610823003628
  23. www.mdpi.com www.mdpi.com
    PD-L1 and HIF-2α Upregulation in Head and Neck Paragangliomas after Embolization
    1
    1. scibot 03 Nov 2023
      RRID:AB_2687655

      DOI: 10.3390/cancers15215199

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    mdpi.com/2072-6694/15/21/5199
  24. www.nature.com www.nature.com
    Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma
    1
    1. scibot 03 Nov 2023
      RRID:AB_2687655

      DOI: 10.1038/s41698-023-00434-4

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    nature.com/articles/s41698-023-00434-4
  25. Oct 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
    1
    1. scibot 27 Oct 2023
      RRID:AB_2687655

      DOI: 10.1016/j.celrep.2023.113318

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    sciencedirect.com/science/article/pii/S221112472301330X
  27. www.sciencedirect.com www.sciencedirect.com
    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
    1
    1. scibot 13 Oct 2023
      RRID:AB_2687655

      DOI: 10.1016/j.molcel.2023.09.007

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    sciencedirect.com/science/article/pii/S1097276523007025
  28. www.sciencedirect.com www.sciencedirect.com
    Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity
    1
    1. scibot 13 Oct 2023
      RRID:AB_2687655

      DOI: 10.1016/j.celrep.2023.113224

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    sciencedirect.com/science/article/pii/S2211124723012366
  29. Sep 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy
    1
    1. scibot 30 Sep 2023
      RRID:AB_2687655

      DOI: 10.1016/j.celrep.2023.113138

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    sciencedirect.com/science/article/pii/S2211124723011506
  31. Aug 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin
    1
    1. scibot 29 Aug 2023
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      DOI: 10.1016/j.cell.2023.07.026

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    sciencedirect.com/science/article/pii/S0092867423008048
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib treatment in patients with BRAF-mutant melanoma brain metastases
    1
    1. scibot 02 Aug 2023
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      DOI: 10.1158/1078-0432.CCR-22-2581

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    ncbi.nlm.nih.gov/pmc/articles/PMC9898142/
  34. Jul 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
    1
    1. scibot 08 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112764

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    sciencedirect.com/science/article/pii/S2211124723007751
  36. Jun 2023
  37. 52.53.155.43 52.53.155.43
    TOPK mediates immune evasion of Renal Cell Carcinoma via upregulating the expression of PD-L1
    1
    1. scibot 30 Jun 2023
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      DOI: 10.1016/j.isci.2023.107185

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    52.53.155.43/9a5455060dac46a2102bae7baf607274e71beaee/1-s2.0-S2589004223012622-main-html.html
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion
    1
    1. scibot 30 Jun 2023
      RRID:AB_2687655

      DOI: 10.3389/fimmu.2023.1189953

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    ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
  39. www.sciencedirect.com www.sciencedirect.com
    ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.chembiol.2023.05.010

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    sciencedirect.com/science/article/pii/S2451945623001538
  40. May 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.ccell.2023.04.011

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    sciencedirect.com/science/article/pii/S153561082300137X
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of PD-1/PD-L1 Co-location with Immunotherapy Outcomes in Non-Small Cell Lung Cancer
    1
    1. scibot 05 May 2023
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      DOI: 10.1158/1078-0432.CCR-21-2649

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    ncbi.nlm.nih.gov/pmc/articles/PMC8776595/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Premorbid use of selective beta-blockers improves sepsis incidence and course: Human cohort and animal model studies
    1
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      DOI: 10.3389/fmed.2023.1105894

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    ncbi.nlm.nih.gov/pmc/articles/PMC10151496/
  44. Apr 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112437

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    sciencedirect.com/science/article/pii/S2211124723004485
  46. www.sciencedirect.com www.sciencedirect.com
    Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer
    1
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      DOI: 10.1016/j.ccell.2023.03.014

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    sciencedirect.com/science/article/pii/S1535610823000879
  47. www.sciencedirect.com www.sciencedirect.com
    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
    1
    1. scibot 12 Apr 2023
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      DOI: 10.1016/j.xcrm.2023.101006

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    sciencedirect.com/science/article/pii/S2666379123001167
  48. www.nature.com www.nature.com
    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
    1
    1. scibot 11 Apr 2023
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      DOI: 10.1038/s41467-023-37617-3

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    nature.com/articles/s41467-023-37617-3
  49. Mar 2023
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of glycometabolism and tumor immune microenvironment for predicting clinical outcomes in gastric cancer
    1
    1. scibot 16 Mar 2023
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      DOI: 10.1016/j.isci.2023.106214

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    ncbi.nlm.nih.gov/pmc/articles/PMC10006618/
  51. www.nature.com www.nature.com
    Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma
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    1. scibot 02 Mar 2023
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      DOI: 10.1038/s41467-023-36769-6

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    nature.com/articles/s41467-023-36769-6
  52. Feb 2023
  53. aacrjournals.org aacrjournals.org
    HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1158/2326-6066.CIR-22-0277

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    aacrjournals.org/cancerimmunolres/article/11/2/228/716209/HRS-Regulates-Small-Extracellular-Vesicle-PD-L1
  54. Jan 2023
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    Cabozantinib plus durvalumab in advanced gastroesophageal cancer and other gastrointestinal malignancies: Phase Ib CAMILLA trial results
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    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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  57. Dec 2022
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  59. Nov 2022
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    Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts
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  65. Sep 2022
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    Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy
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  68. Aug 2022
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  76. May 2022
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    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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  80. Mar 2022
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    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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  82. Feb 2022
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    PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
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  88. Dec 2021
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    Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance
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  91. Nov 2021
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  107. Jun 2021
  108. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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  109. May 2021
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    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kynurenine/Tryptophan Ratio as a Potential Blood-Based Biomarker in Non-Small Cell Lung Cancer
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    Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity
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    Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus
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  114. Apr 2021
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    HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component
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    An optimized protocol for patient-derived xenograft in humanized mice to evaluate the role of IL-34 in immunotherapeutic resistance
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  118. www.nature.com www.nature.com
    The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation
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    Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor
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  120. Feb 2021
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    Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma
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    Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing
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  123. Jan 2021
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A distinct innate immune signature marks progression from mild to severe COVID-19
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  125. Sep 2020
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    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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    FOXD3 Regulates VISTA Expression in Melanoma
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Indoleamine 2,3-Dioxygenase 2 Immunohistochemical Expression in Resected Human Non-small Cell Lung Cancer: A Potential New Prognostic Tool
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      DOI: 10.3389/fimmu.2020.00839

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    Small Molecule Inhibition of GSK-3 Specifically Inhibits the Transcription of Inhibitory Co-receptor LAG-3 for Enhanced Anti-tumor Immunity
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      DOI: 10.1016/j.celrep.2020.01.076

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  133. Jan 2020
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    Tracing Oncogene Rearrangements in the Mutational History of Lung Adenocarcinoma
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      DOI: 10.1016/j.cell.2019.05.013

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    Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy
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      DOI: 10.1016/j.ccell.2019.06.008

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    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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    The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer
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      DOI: 10.1016/j.celrep.2019.04.098

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    Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy
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      DOI: 10.1016/j.ccell.2019.01.003

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  140. www.cell.com www.cell.com
    Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
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      DOI: 10.1016/j.cell.2019.02.016

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    cell.com/cell/fulltext/S0092-8674(19)30165-5
  141. Nov 2018
  142. www.sciencedirect.com www.sciencedirect.com
    Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny
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    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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  145. Nov 2017
  146. www.sciencedirect.com www.sciencedirect.com
    Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
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