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Oct 2026
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Microglia with distinct origins and non-canonical phenotypes coexist within the border-like niche of the brain’s circumventricular organs

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Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression

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Sep 2026
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Albumin uptake through FcRn promotes tumor-associated macrophage maturation and albumin-bound immunotherapy response

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Cancer-Intrinsic Protein Neddylation Modulates the Intratumoral Immune Landscape to Constrain Immune Checkpoint Blockade Therapy

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pmc.ncbi.nlm.nih.gov/articles/PMC13535320/
Aug 2026
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Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression

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Jul 2026
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Tumor-Associated Macrophages Produce PGE2 to Promote CD8+ T Cell Exhaustion and Drive Resistance to PD-L1 Blockade in Microsatellite Stable Colorectal Cancer

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aacrjournals.org/cancerres/article/86/3/785/771916/Tumor-Associated-Macrophages-Produce-PGE2-to
Jun 2026
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Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance

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Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

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  DOI: 10.1158/2767-9764.CRC-25-0639
  
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May 2026
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Uncovering spatially resolved functional genomics with CRISPR screen sequencing

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  DOI: 10.1016/j.cell.2026.04.049
  
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Nociceptive innervation limits tertiary lymphoid structures to promote lung cancer

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  DOI: 10.1016/j.cell.2026.04.038
  
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Dendritic cell redundancy enables priming of anti-tumor CD4+ T cells in pancreatic cancer

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  DOI: 10.1016/j.ccell.2026.04.005
  
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Apr 2026
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Macrophage-mediated refinement of the dural lymphatic regulates social behavior

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1. scibot 25 Apr 2026
  
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  DOI: 10.1016/j.neuron.2026.03.019
  
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Oncogenic and tumor-suppressive forces converge on a progenitor niche at the benign-to-malignant transition

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.03.032
  
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Mar 2026
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NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.016
  
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Immunogenic tumor cell death and T-cell-derived IFN-γ elicit tumoricidal macrophages to potentiate OX40 immunotherapy

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102699
  
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Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.02.013
  
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Feb 2026
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Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia

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1. scibot 13 Feb 2026
  
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  DOI: 10.1016/j.ccell.2026.01.014
  
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Jan 2026
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Myeloid CD209 impairs T-cell activation by inducing ICAM-2–ERM–dependent cortical stiffening

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1. scibot 27 Jan 2026
  
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  DOI: 10.64898/2026.01.19.699861
  
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biorxiv.org/content/10.64898/2026.01.19.699861v1
Nov 2025
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Vitamin B6 preserves the stemness-like phenotypes and antitumor ability of CD8+ T cells

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  DOI: 10.1016/j.devcel.2025.10.017
  
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Predominant mutated non-canonical tumor-specific antigens identified by proteogenomics demonstrate immunogenicity and tumor suppression in CRC

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Oct 2025
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Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance

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  DOI: 10.1016/j.cell.2025.09.029
  
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Aug 2025
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A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma

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  DOI: 10.1158/2159-8290.CD-24-1425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
Jul 2025
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Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

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RORγ Bridges Cancer-Driven Lipid Dysmetabolism and Myeloid Immunosuppression

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  DOI: 10.1158/2159-8290.CD-24-0199
  
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Jun 2025
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CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma

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  DOI: 10.1016/j.ccell.2025.05.013
  
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Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy

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May 2025
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GPR65 Inactivation in Tumor Cells Drives Antigen-Independent CAR T-cell Resistance via Macrophage Remodeling

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Macrophages direct location-dependent recall of B cell memory to vaccination

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Feb 2025
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A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination

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Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2

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  DOI: 10.1016/j.cell.2025.01.025
  
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Jan 2025
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Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance

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  DOI: 10.1016/j.celrep.2024.115227
  
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Nov 2024
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Stepwise Ultra-pH-Sensitive Micelles Overcome a pKa Barrier for Systemic Lymph Node Delivery

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1. scibot 29 Nov 2024
  
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  DOI: 10.1021/acsnano.4c00876
  
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Microbiota-induced alteration of kynurenine metabolism in macrophages drives formation of creeping fat in Crohn’s disease

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.chom.2024.10.008
  
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Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection

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  DOI: 10.1016/j.cell.2024.10.028
  
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Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy

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Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

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Endothelial metabolic control of insulin sensitivity through resident macrophages

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Stepwise Ultra-pH-Sensitive Micelles Overcome a pKa Barrier for Systemic Lymph Node Delivery

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Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure

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Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice

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p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression

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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

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Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy

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Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence

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Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma

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Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma

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25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages

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Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

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A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer

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Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48

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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin

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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer

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Apoptotic cell fragments locally activate tingible body macrophages in the germinal center

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The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

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Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1

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Unravelling the sex-specific diversity and functions of adrenal gland macrophages

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Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche

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The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade

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A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx

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Resolving the immune landscape of human prostate at a single-cell level in health and cancer

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Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections

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Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response

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Activating a collaborative innate-adaptive immune response to control metastasis

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Jun 2021
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Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis

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May 2021
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Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues

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Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance

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Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity

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  DOI: 10.1016/j.ccell.2020.05.020
  
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Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

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Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors

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Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria

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Untitled document

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  DOI: 10.1016/j.cell.2019.03.025
  
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Untitled document

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  DOI: 10.1016/j.stem.2019.01.011
  
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LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis

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Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis

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Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance

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High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

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