72 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
    1
    1. scibot 14 Dec 2024
      RRID:AB_2687796

      DOI: 10.1016/j.ccell.2024.11.008

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    sciencedirect.com/science/article/pii/S1535610824004434
  3. 52.53.155.43 52.53.155.43
    Enhancing Immune Response and Survival in Hepatocellular Carcinoma with Novel Oncolytic Jurona Virus and Immune Checkpoint Blockade
    1
    1. scibot 06 Dec 2024
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      DOI: 10.1016/j.omton.2024.200913

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    52.53.155.43/b17d322494c44a28e0d2e52b4d7ea9e056092d31/Enhancing Immune Response and Survival in Hepatocellular Carcinoma with Novel Oncolytic Jurona Virus and Immune Checkpoint Blockade-html.html
  4. Nov 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
    1
    1. scibot 24 Nov 2024
      RRID:AB_2687796

      DOI: 10.1016/j.immuni.2024.10.013

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    sciencedirect.com/science/article/pii/S107476132400493X
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
    1
    1. scibot 08 Nov 2024
      RRID:AB_2687796

      DOI: 10.1158/2326-6066.CIR-24-0463

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532741/
  7. Oct 2024
  8. www.biorxiv.org www.biorxiv.org
    Trem2 deficiency attenuates breast cancer tumor growth in lean, but not obese or weight loss, mice and is associated with alterations of clonal T cell populations
    1
    1. scibot 02 Oct 2024
      RRID:AB_2687796

      DOI: 10.1101/2024.09.25.614811

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    biorxiv.org/content/10.1101/2024.09.25.614811v1
  9. Sep 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Protocol to quantify the activation dynamics of tumor-associated T cells in mice by functional intravital microscopy
    1
    1. scibot 26 Sep 2024
      AB_2687796

      DOI: 10.1016/j.xpro.2024.103310

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    sciencedirect.com/science/article/pii/S2666166724004751
  11. www.sciencedirect.com www.sciencedirect.com
    Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation
    1
    1. scibot 26 Sep 2024
      AB_2687796

      DOI: 10.1016/j.immuni.2024.08.015

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    sciencedirect.com/science/article/pii/S1074761324004151
  12. www.sciencedirect.com www.sciencedirect.com
    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
    1
    1. scibot 10 Sep 2024
      AB_2687796

      DOI: 10.1016/j.cell.2024.08.007

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    sciencedirect.com/science/article/pii/S0092867424008985
  13. www.sciencedirect.com www.sciencedirect.com
    Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment
    1
    1. scibot 04 Sep 2024
      AB_2687796

      DOI: 10.1016/j.celrep.2024.114697

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    sciencedirect.com/science/article/pii/S2211124724010489
  14. www.sciencedirect.com www.sciencedirect.com
    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
    1
    1. scibot 04 Sep 2024
      AB_2687796

      DOI: 10.1016/j.xcrm.2024.101711

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    sciencedirect.com/science/article/pii/S2666379124004324
  15. Aug 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
    1
    1. scibot 25 Aug 2024
      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2024.101686

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    ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
  17. www.sciencedirect.com www.sciencedirect.com
    TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function
    1
    1. scibot 23 Aug 2024
      AB_2687796

      DOI: 10.1016/j.xcrm.2024.101696

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    sciencedirect.com/science/article/pii/S2666379124004178
  18. Jul 2024
  19. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
    1
    1. scibot 25 Jul 2024
      RRID:AB_2687796

      DOI: 10.1126/science.adh4567

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    science.org/doi/10.1126/science.adh4567
  20. www.biorxiv.org www.biorxiv.org
    Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function
    1
    1. scibot 16 Jul 2024
      RRID:AB_2687796

      DOI: 10.1101/2024.07.01.601087

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    biorxiv.org/content/10.1101/2024.07.01.601087v1
  21. May 2024
  22. www.sciencedirect.com www.sciencedirect.com
    A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy
    1
    1. scibot 30 May 2024
      RRID:AB_2687796

      DOI: 10.1016/j.ebiom.2024.105167

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    sciencedirect.com/science/article/pii/S2352396424002020
  23. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance
    1
    1. scibot 21 May 2024
      RRID:AB_2687796

      DOI: 10.1016/j.immuni.2024.04.024

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    sciencedirect.com/science/article/pii/S1074761324002292
  24. www.sciencedirect.com www.sciencedirect.com
    Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
    1
    1. scibot 09 May 2024
      AB_2687796

      DOI: 10.1016/j.cell.2024.04.015

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    sciencedirect.com/science/article/pii/S0092867424004100
  25. Apr 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
    1
    1. scibot 30 Apr 2024
      BioXcellBP0273

      DOI: 10.1016/j.xcrm.2024.101528

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    sciencedirect.com/science/article/pii/S2666379124001976
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The diversity of inhibitory receptor co-expression patterns of exhausted CD8+ T cells in oropharyngeal carcinoma
    1
    1. scibot 28 Apr 2024
      RRID:AB_2687796

      DOI: 10.1016/j.isci.2024.109668

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    ncbi.nlm.nih.gov/pmc/articles/PMC11035373/
  28. www.sciencedirect.com www.sciencedirect.com
    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
    1
    1. scibot 24 Apr 2024
      RRID:AB_2687796

      DOI: 10.1016/j.cell.2024.03.039

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    sciencedirect.com/science/article/pii/S0092867424003556
  29. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
    1
    1. scibot 03 Apr 2024
      RRID:AB_2687796

      DOI: 10.1038/s41467-024-47069-y

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    nature.com/articles/s41467-024-47069-y
  30. Mar 2024
  31. www.thno.org www.thno.org
    Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
    1
    1. scibot 30 Mar 2024
      RRID:AB_2687796

      DOI: 10.7150/thno.90322

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    thno.org/v14p0436.htm
  32. www.sciencedirect.com www.sciencedirect.com
    Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
    1
    1. scibot 15 Mar 2024
      RRID:AB_2687796

      DOI: 10.1016/j.cell.2024.02.022

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    sciencedirect.com/science/article/pii/S0092867424002241
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    1
    1. scibot 12 Mar 2024
      RRID:AB_2687796

      DOI: 10.1186/s13046-024-02985-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10921725/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth
    1
    1. scibot 03 Mar 2024
      RRID:AB_2687796

      DOI: 10.1038/s44321-023-00013-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897164/
  35. Feb 2024
  36. www.sciencedirect.com www.sciencedirect.com
    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
    1
    1. scibot 28 Feb 2024
      RRID:AB_2687796

      DOI: 10.1016/j.molcel.2024.01.024

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    sciencedirect.com/science/article/pii/S1097276524000911
  37. aacrjournals.org aacrjournals.org
    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion
    2
    1. scibot 23 Feb 2024
      RRID:AB_2687796

      DOI: 10.1158/0008-5472.CAN-23-2049

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      RRID:AB_2687796

      DOI: 10.1158/0008-5472.CAN-23-2049

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    aacrjournals.org/cancerres/article/84/3/405/733849/RNA-Methyltransferase-FTSJ3-Regulates-the-Type-I
  38. Jan 2024
  39. aacrjournals.org aacrjournals.org
    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
    1
    1. scibot 11 Jan 2024
      RRID:AB_2687796

      DOI: 10.1158/2159-8290.CD-22-1301

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    aacrjournals.org/cancerdiscovery/article/13/12/2566/731588/Formate-Supplementation-Enhances-Antitumor-CD8-T
  40. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1126/sciimmunol.abq2424

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    52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
  41. Dec 2023
  42. www.embopress.org www.embopress.org
    Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth
    1
    1. scibot 29 Dec 2023
      RRID:AB_2687796

      DOI: 10.1038/s44321-023-00013-x

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    embopress.org/doi/10.1038/s44321-023-00013-x
  43. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
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      DOI: 10.1158/2159-8290.cd-22-1301

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  44. Oct 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy
    1
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      AB_2687796

      DOI: 10.3389/fimmu.2023.1237715

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524267/
  46. Sep 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma
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    1. scibot 09 Sep 2023
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      DOI: 10.1158/2159-8290.CD-22-0869

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    ncbi.nlm.nih.gov/pmc/articles/PMC10481130/
  49. Aug 2023
  50. www.sciencedirect.com www.sciencedirect.com
    KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
    1
    1. scibot 25 Aug 2023
      RRID:AB_2687796

      DOI: 10.1016/j.ccell.2023.07.002

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    sciencedirect.com/science/article/abs/pii/S1535610823002428
  51. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
    2
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      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101151

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      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101151

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    52.53.155.43/75914c2645b295883453ae6f0848b8ff04ccb7e0/PIIS266637912300304X-html.html
  52. www.sciencedirect.com www.sciencedirect.com
    Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC
    1
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      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101150

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    sciencedirect.com/science/article/pii/S2666379123003038
  53. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
    2
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      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101145

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  54. Jul 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Tumor aerobic glycolysis confers immune evasion through modulating sensitivity to T cell-mediated bystander killing via TNF-α
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    Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis
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  57. Apr 2023
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    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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  61. Feb 2023
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    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
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  63. Jul 2022
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    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
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  65. Jun 2022
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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  67. Apr 2022
  68. aacrjournals.org aacrjournals.org
    mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
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  69. Feb 2022
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    Flow cytometric analysis of CD4+ T cell reactivation following anti-PD1 immunotherapy in a transgenic mouse model
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  71. Nov 2021
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    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
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    Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy
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  74. Oct 2021
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    Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling
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  76. Sep 2021
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    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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    Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength
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    Activating a collaborative innate-adaptive immune response to control metastasis
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  80. Aug 2021
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    Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
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    Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts
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    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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  84. Jul 2021
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    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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  86. Jun 2021
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    Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
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  88. May 2021
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    Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
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  90. Dec 2020
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    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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  92. Sep 2020
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    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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  94. Jan 2020
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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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    Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
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    RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
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  100. Nov 2018
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    Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
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