58 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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    1. scibot 18 Jul 2024
      AB_2687845

      DOI: 10.1016/j.cell.2024.06.012

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    sciencedirect.com/science/article/pii/S0092867424006524
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity
    1
    1. scibot 17 May 2024
      RRID:AB_2687845

      DOI: 10.1016/j.chembiol.2024.04.005

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    sciencedirect.com/science/article/pii/S2451945624001673
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    CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity
    1
    1. scibot 16 May 2024
      RRID:AB_2687845

      DOI: 10.1016/j.immuni.2024.04.017

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    sciencedirect.com/science/article/pii/S107476132400222X
  6. Mar 2024
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    NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113898

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    2. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113898

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    sciencedirect.com/science/article/pii/S2211124724002262
  8. Feb 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
    2
    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.immuni.2024.01.011

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    2. scibot 14 Feb 2024
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    sciencedirect.com/science/article/pii/S1074761324000360
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    Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113712

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    sciencedirect.com/science/article/pii/S2211124724000408
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    Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.immuni.2023.12.006

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    sciencedirect.com/science/article/pii/S107476132300537X
  12. Jan 2024
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    Bispecific dendritic-T cell engager potentiates anti-tumor immunity
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.011

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    sciencedirect.com/science/article/pii/S0092867423013430
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    Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101377

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    sciencedirect.com/science/article/pii/S2666379123006067
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    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
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    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.013

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    sciencedirect.com/science/article/pii/S1535610823004415
  16. Dec 2023
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    Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.immuni.2023.11.018

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    sciencedirect.com/science/article/pii/S1074761323005009
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    Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
    1
    1. scibot 17 Dec 2023
      RRID:AB_2687845

      DOI: 10.1016/j.immuni.2023.11.005

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    sciencedirect.com/science/article/pii/S1074761323004879
  19. Oct 2023
  20. www.embopress.org www.embopress.org
    IL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4+ T cells
    1
    1. scibot 20 Oct 2023
      RRID:AB_2687845

      DOI: 10.15252/emmm.202317713

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    embopress.org/doi/10.15252/emmm.202317713
  21. 52.53.155.43 52.53.155.43
    Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors
    2
    1. scibot 14 Oct 2023
      RRID:AB_2687845

      DOI: 10.1101/2023.08.11.553007

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      DOI: 10.1101/2023.08.11.553007

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    52.53.155.43/7eb24570d443d458f8fd7700f91970ed0d945838/2023.08.11.553007v1.full-html.html
  22. Sep 2023
  23. www.sciencedirect.com www.sciencedirect.com
    STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells
    1
    1. scibot 16 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113108

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    sciencedirect.com/science/article/pii/S2211124723011191
  24. Aug 2023
  25. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
    2
    1. scibot 17 Aug 2023
      RRID:AB_2687845

      DOI: 10.1016/j.xcrm.2023.101151

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    2. scibot 11 Aug 2023
      RRID:AB_2687845

      DOI: 10.1016/j.xcrm.2023.101151

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    52.53.155.43/75914c2645b295883453ae6f0848b8ff04ccb7e0/PIIS266637912300304X-html.html
  26. 52.53.155.43 52.53.155.43
    SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine
    2
    1. scibot 17 Aug 2023
      RRID:AB_2687845

      DOI: 10.1016/j.celrep.2023.112940

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      DOI: 10.1016/j.celrep.2023.112940

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    52.53.155.43/746dceaaaecd8ad8008d9df523b985f7a77f181a/PIIS2211124723009518-html.html
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    Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC
    1
    1. scibot 16 Aug 2023
      RRID:AB_2687845

      DOI: 10.1016/j.xcrm.2023.101150

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    sciencedirect.com/science/article/pii/S2666379123003038
  28. 52.53.155.43 52.53.155.43
    Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues
    2
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112924

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      AB_2687845

      DOI: 10.1016/j.celrep.2023.112924

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    52.53.155.43/106172e3dc158d3c4be84043bc17f2fcec9bdf8f/PIIS221112472300935X-html.html
  29. 52.53.155.43 52.53.155.43
    Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells
    2
    1. scibot 12 Aug 2023
      RRID:AB_2687845

      DOI: 10.1016/j.celrep.2023.112876

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      DOI: 10.1016/j.celrep.2023.112876

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    52.53.155.43/7d9bf3333b9425342ca4204697d643342388db9f/PIIS2211124723008872-html.html
  30. Jul 2023
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    A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity
    1
    1. scibot 14 Jul 2023
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      DOI: 10.1016/j.ccell.2023.06.008

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    sciencedirect.com/science/article/pii/S1535610823002180
  32. Jun 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.011

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    sciencedirect.com/science/article/pii/S1074761323002285
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    The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.008

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    sciencedirect.com/science/article/pii/S107476132300225X
  35. Apr 2023
  36. www.sciencedirect.com www.sciencedirect.com
    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
    1
    1. scibot 29 Apr 2023
      RRID:AB_2687845

      DOI: 10.1016/j.celrep.2023.112436

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    sciencedirect.com/science/article/pii/S2211124723004473
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    Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.ccell.2023.04.001

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    sciencedirect.com/science/article/pii/S1535610823001174
  38. Mar 2023
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    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.cmet.2023.02.013

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    sciencedirect.com/science/article/pii/S1550413123000499
  40. Jan 2023
  41. www.sciencedirect.com www.sciencedirect.com
    CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor
    1
    1. scibot 28 Jan 2023
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      DOI: 10.1016/j.immuni.2022.12.002

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    sciencedirect.com/science/article/pii/S1074761322006069
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.immuni.2022.12.006

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    sciencedirect.com/science/article/pii/S1074761322006422
  43. Nov 2022
  44. www.sciencedirect.com www.sciencedirect.com
    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
    1
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      DOI: 10.1016/j.immuni.2022.10.020

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    sciencedirect.com/science/article/pii/S1074761322005611
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    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
    1
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      DOI: 10.1016/j.celrep.2022.111582

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    sciencedirect.com/science/article/pii/S2211124722014474
  46. Oct 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
    1
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      DOI: 10.1016/j.immuni.2022.09.014

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    sciencedirect.com/science/article/pii/S1074761322005088
  48. Sep 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
    1
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      DOI: 10.1016/j.ccell.2022.08.014

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    sciencedirect.com/science/article/pii/S1535610822003786
  50. Jun 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.immuni.2022.05.012

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    sciencedirect.com/science/article/pii/S1074761322002321
  52. May 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
    1
    1. scibot 27 May 2022
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      DOI: 10.1016/j.ccell.2022.05.004

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    sciencedirect.com/science/article/pii/S153561082200215X
  54. Sep 2021
  55. www.sciencedirect.com www.sciencedirect.com
    CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection
    1
    1. scibot 16 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109696

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  56. Aug 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_2687845

      DOI: 10.1016/j.celrep.2018.10.074

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  58. Jul 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells
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      RRID:AB_2687845

      DOI: 10.1016/j.celrep.2018.10.074

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  60. Apr 2021
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    A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer
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      RRID:AB_2687845

      DOI: 10.1016/j.cell.2020.08.053

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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
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  63. Mar 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging
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  65. Feb 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1
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      RRID:AB_2687845

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  67. Nov 2020
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1
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      RRID:AB_2687845

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  69. Sep 2020
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    Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural Control of SIV: ANRS SIC Study
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      RRID:AB_2687845

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    Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
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  72. Jan 2020
  73. www.sciencedirect.com www.sciencedirect.com
    Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells
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      RRID:AB_2687845

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    TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
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    Discovery of Small Molecules for the Reversal of T Cell Exhaustion
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      RRID:AB_2687845

      DOI: 10.1016/j.celrep.2019.10.119

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  76. www.sciencedirect.com www.sciencedirect.com
    Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States
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      RRID:AB_2687845

      DOI: 10.1016/j.immuni.2019.03.004

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  77. Nov 2018
  78. www-sciencedirect-com.ezproxy.is.ed.ac.uk www-sciencedirect-com.ezproxy.is.ed.ac.uk
    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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    Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells
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  80. Nov 2017
  81. www.sciencedirect.com www.sciencedirect.com
    Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
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      Anti-mouse TCF1 (clone S33-966)BDCat# 564217

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