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  1. Last 7 days
  2. elifesciences.org elifesciences.org
    Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress
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    1. scibot 20 Dec 2024
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      DOI: 10.7554/eLife.96284

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    elifesciences.org/articles/96284
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The X-linked intellectual disability gene CUL4B is critical for memory and synaptic function
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    1. scibot 20 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    2. scibot 19 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    3. scibot 18 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    4. scibot 17 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    5. scibot 16 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    6. scibot 15 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    pmc.ncbi.nlm.nih.gov/articles/PMC11619648/
  4. Dec 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The X-linked intellectual disability gene CUL4B is critical for memory and synaptic function
    4
    1. scibot 14 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    2. scibot 13 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    3. scibot 12 Dec 2024
      RRID:AB_2687938

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    4. scibot 11 Dec 2024
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      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer
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    1. scibot 11 Dec 2024
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      DOI: 10.1136/jitc-2024-009905

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    pmc.ncbi.nlm.nih.gov/articles/PMC11624798/
  7. www.sciencedirect.com www.sciencedirect.com
    Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis
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    sciencedirect.com/science/article/pii/S1550413124004510
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    Chemical activation of mitochondrial ClpP to modulate energy metabolism of CD4+ T cell for inflammatory bowel diseases treatment
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    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.xcrm.2024.101840

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    sciencedirect.com/science/article/pii/S2666379124006116
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    Structure-guided development of selective caseinolytic protease P agonists as antistaphylococcal agents
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    sciencedirect.com/science/article/pii/S2666379124006086
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    Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injury
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.chom.2024.11.002

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    sciencedirect.com/science/article/pii/S1931312824004086
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    Carbonic anhydrase 2 facilitates sorafenib resistance by counteracting MCT4-mediated intracellular pH dysregulation in HCC
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.celrep.2024.114996

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    sciencedirect.com/science/article/pii/S2211124724013470
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    ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis
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      DOI: 10.1016/j.celrep.2024.114988

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  13. Nov 2024
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis
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    1. scibot 21 Nov 2024
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  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells
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      DOI: 10.1016/j.isci.2024.111176

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  16. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia–reperfusion injury
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    1. scibot 14 Nov 2024
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      DOI: 10.1096/fj.202401056R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401056R
  17. www.sciencedirect.com www.sciencedirect.com
    ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma
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    1. scibot 11 Nov 2024
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond
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    1. scibot 10 Nov 2024
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      DOI: 10.3389/fphar.2024.1496639

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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NOSTRIN is involved in benign prostatic hyperplasia via inhibition of proliferation, oxidative stress, and inflammation in prostate epithelial cells
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    1. scibot 07 Nov 2024
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      DOI: 10.21037/tau-24-209

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    pmc.ncbi.nlm.nih.gov/articles/PMC11491235/
  20. www.jneurosci.org www.jneurosci.org
    Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development
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      DOI: 10.1523/JNEUROSCI.0072-24.2024

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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Grb7 Ablation in Mice Improved Glycemic Control, Enhanced Insulin Signaling, and Increased Abdominal fat Mass in Females
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    pmc.ncbi.nlm.nih.gov/articles/PMC11491842/
  22. Oct 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The AGEs/RAGE Signaling Pathway Regulates NLRP3-Mediated Neuronal Pyroptosis After MCAO Injury in Lepr−/− Obese Rats
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    1. scibot 08 Oct 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11453143/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis
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    1. scibot 05 Oct 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11440250/
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    Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice
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  26. Sep 2024
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In utero morphological and functional properties of bovine trophoblastic vesicles
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      DOI: 10.1002/mrd.23767

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    onlinelibrary.wiley.com/doi/10.1002/mrd.23767
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    Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
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    Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB
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    sciencedirect.com/science/article/pii/S240584402413784X
  30. Aug 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality
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      DOI: 10.7554/eLife.92826

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    ncbi.nlm.nih.gov/pmc/articles/PMC11329274/
  32. www.sciencedirect.com www.sciencedirect.com
    Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2211124724009203
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    IFI-16 inhibition attenuates myocardial remodeling following myocardial infarction
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    Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma
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  35. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2025/09000/enhanced_autophagic_clearance_of_amyloid___via.25.aspx
  36. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer
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    cellandbioscience.biomedcentral.com/articles/10.1186/s13578-021-00687-1
  37. www.sciencedirect.com www.sciencedirect.com
    The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
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    sciencedirect.com/science/article/pii/S1097276524005793
  38. Jul 2024
  39. link.springer.com link.springer.com
    CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A
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      DOI: 10.1007/s00018-024-05285-1

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    link.springer.com/article/10.1007/s00018-024-05285-1
  40. www.cell.com www.cell.com
    A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma
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    cell.com/cell-reports/abstract/S2211-1247(24)00879-9
  41. 52.53.155.43 52.53.155.43
    Magnetic-vortex nanodonuts enhance ferroptosis effect of tumor ablation through an integrated imaging-guided hyperthermia/radiosensitization strategy
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  42. link.springer.com link.springer.com
    Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats
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    Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
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    Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis
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  45. Jun 2024
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    Capturing acyl–enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification
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    Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia
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    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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  49. May 2024
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    Protocol for identifying OXCT1-mediated LACTB succinylation sites in vitro
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    CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial–mesenchymal transition in triple-negative breast cancer
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  54. Apr 2024
  55. www.sciencedirect.com www.sciencedirect.com
    Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    ISGylation by HERCs facilitates STING activation
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    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects
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    Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis
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    Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling
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  67. Mar 2024
  68. www.sciencedirect.com www.sciencedirect.com
    Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway
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    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
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    Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions
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    Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway
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    Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
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  74. Feb 2024
  75. www.nature.com www.nature.com
    Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer
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    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
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    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating HMGB1 as a Potential Serum Biomarker for Early Diabetic Nephropathy Monitoring by Quantitative Proteomics
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  80. Jan 2024
  81. www.sciencedirect.com www.sciencedirect.com
    Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation
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    Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells
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    Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin
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    OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB
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    CHTOP Alleviates Cerebral Ischemia/Reperfusion-Induced Injury by Regulating RNA Alternative Splicing
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    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
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    Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
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    YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring
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    Choroid plexus mast cells drive tumor-associated hydrocephalus
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    Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy
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    Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity
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    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
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    Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis
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    AKAP150 from Nucleus Accumbens Dopamine D1 and D2 Receptor-Expressing Medium Spiny Neurons Regulates Morphine Withdrawal
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    Culin5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF
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    K+/Cl− cotransporter 2 (KCC2) and Na+/[... formula ...] cotransporter 1 (NBCe1) interaction modulates profile of KCC2 phosphorylation
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    Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice
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    Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells
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    Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D
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    Focused Low-Intensity Pulsed Ultrasound Alleviates Osteoarthritis via Restoring Impaired FUNDC1-Mediated Mitophagy
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    Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
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    CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis
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    Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
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    Hedgehog receptors exert immune-surveillance roles in the epidermis across species
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    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
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    Characterisation of dominant-negative GH receptor variants reveals a potential therapeutic target for short stature
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    PPT1 Regulation Of HSP90α Depalmitoylation Participates In The Pathogenesis Of Hyperandrogenism
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    Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma
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    The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region
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  171. Dec 2022
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    GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum
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    GABA regulates IL-1β production in macrophages
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    Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
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  176. Nov 2022
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    NVP-BHG712 against postmenopausal osteoporosis in mice by targeting Cathepsin K
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    Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis
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    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    Essential role of MESP1-RING1A complex in cardiac differentiation
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    HBO1 catalyzes lysine benzoylation in mammalian cells
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    Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
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    Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
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  186. Oct 2022
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    Cortisol stimulates local progesterone withdrawal through induction of AKR1C1 in human amnion fibroblasts at parturition
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    Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas
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    Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice
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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
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    FBXL6 depletion restrains clear cell renal cell carcinoma progression
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    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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  195. Sep 2022
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    CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions
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    Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages
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  198. Aug 2022
  199. journals.lww.com journals.lww.com
    Chronic spinal cord compression associated with... : Neural Regeneration Research
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    A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway
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    NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes
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  202. Jul 2022
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    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate
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  205. Jun 2022
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    The Role of Ciliopathy-Associated Type 3 Adenylyl Cyclase in Infanticidal Behavior in Virgin Adult Male Mice
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    BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging
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    SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production
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    GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease
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    An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity
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    Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine
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    TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury
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    VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion
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    Single-cell sequencing reveals the new existence form of dermal papilla cells in the hair follicle regeneration of cashmere goats
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