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IRE-1α/XBP-1s axis determines phosphodiesterase 1c activation inducing vascular endothelial cell damage, contributes to cerebral vascular injury and neuroinflammation

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sciencedirect.com/science/article/pii/S1567576926014001
Aug 2026
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p97 Inhibition Synergistically Enhances Hypomethylating Therapy Through Targeting of PLK1 in Acute Myeloid Leukemia

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  DOI: 10.1158/2767-9764.CRC-26-0035
  
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aacrjournals.org/cancerrescommun/article/6/6/1509/786204/p97-Inhibition-Synergistically-Enhances
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The coordinated actions of metformin in the intestine and liver improves hyperglycemia

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  DOI: 10.1016/j.celrep.2026.117791
  
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sciencedirect.com/science/article/pii/S2211124726008697
Jun 2026
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FGF21 reduces ER stress by enhancing the unfolded protein and integrated stress responses through increased sulfide signaling

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1. scibot 17 Jun 2026
  
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STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation

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2026.05.25.727656.full-html.html

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54.241.53.176/32c5a2f4753f61ee28ea249cdeb257eadb13655d/2026.05.25.727656.full-html.html
May 2026
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Calcium-mediated calreticulin-IRE1α interaction drives dynamic fluctuation of IRE1α activity under chronic endoplasmic reticulum stress

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1. scibot 09 May 2026
  
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  DOI: 10.1038/s41467-026-70679-7
  
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Apr 2026
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FAM134B Controls Collagen I Dynamics in Hepatic Stellate Cell-Driven Fibrosis

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1. scibot 24 Apr 2026
  
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  DOI: 10.1152/ajpgi.00170.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12818557/
Dec 2025
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misra-et-al-2025-fam134b-controls-collagen-i-dynamics-in-hepatic-stellate-cell-driven-fibrosis-html.html

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54.241.53.176/7d61701eda67e5c30e5b80a91af04eaa9e6cd528/misra-et-al-2025-fam134b-controls-collagen-i-dynamics-in-hepatic-stellate-cell-driven-fibrosis-html.html
Aug 2025
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A mechano-resistance mechanism in skin adapts to terrestrial locomotion

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.012
  
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cell.com/cell/abstract/S0092-8674(25)00801-3
Jul 2025
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1-s2.0-S2589004225013823-main-html.html

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113121
  
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May 2025
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A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115695
  
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sciencedirect.com/science/article/pii/S2211124725004668
Apr 2025
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Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress

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  DOI: 10.1080/0886022X.2025.2483986
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11951319/
Jan 2025
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Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway

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  DOI: 10.1016/j.celrep.2024.115126
  
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sciencedirect.com/science/article/pii/S2211124724014773
Jun 2024
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Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114358
  
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The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110196
  
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May 2024
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Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression

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1. scibot 08 May 2024
  
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  DOI: 10.1016/j.cmet.2024.04.014
  
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sciencedirect.com/science/article/pii/S1550413124001347
Apr 2024
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Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum

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  DOI: 10.1016/j.devcel.2024.03.014
  
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sciencedirect.com/science/article/pii/S1534580724001801
Aug 2023
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The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation

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52.53.155.43/8a075ef675e11ca05cb4fe9fd629f036036ec570/PIIS2211124723009798-html.html
Jul 2023
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MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

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Apr 2023
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VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms

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  DOI: 10.1016/j.celrep.2023.112209
  
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sciencedirect.com/science/article/pii/S2211124723002206
Apr 2022
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Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-α-driven inflammation and ER stress

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sciencedirect.com/science/article/pii/S2352396419307297
Feb 2022
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Novel Pathogenic de novo INS p.T97P Variant Presenting with Severe Neonatal DKA

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  DOI: 10.1210/endocr/bqab246
  
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academic.oup.com/endo/article/163/2/bqab246/6458485
Jan 2022
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Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection

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  DOI: 10.1371/journal.pntd.0009192
  
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AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia

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  DOI: 10.1016/j.celrep.2021.110197
  
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sciencedirect.com/science/article/pii/S2211124721017010
Dec 2021
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The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

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1. scibot 08 Dec 2021
  
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  DOI: 10.7554/eLife.73215
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8635982/
Nov 2021
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TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells

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  DOI: 10.1210/endocr/bqab212
  
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academic.oup.com/endo/article/163/1/bqab212/6382455
Oct 2021
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Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers

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  DOI: 10.1158/0008-5472.CAN-21-1545
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8723353/
Sep 2021
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ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance

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  DOI: 10.1016/j.cell.2021.08.036
  
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Jul 2021
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Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides

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  DOI: 10.1016/j.celrep.2021.109312
  
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sciencedirect.com/science/article/pii/S2211124721006884
Sep 2020
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TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation

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  DOI: 10.1016/j.cmet.2020.03.007
  
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sciencedirect.com/science/article/pii/S1550413120301224
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Genome-wide Survey of Ribosome Collision

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  DOI: 10.1016/j.celrep.2020.107610
  
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sciencedirect.com/science/article/pii/S2211124720305593
Jan 2020
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BPS Publications

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1. scibot 13 Jan 2020
  
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  DOI: 10.1111/bph.14713
  
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6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels

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  DOI: 10.1016/j.chembiol.2019.05.006
  
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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

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  DOI: 10.1016/j.ccell.2019.01.006
  
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Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.03.005
  
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