38 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
    1
    1. scibot 26 Apr 2024
      RRID:AB_2688011

      DOI: 10.1016/j.cell.2024.03.022

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    sciencedirect.com/science/article/pii/S0092867424003131
  3. Feb 2024
  4. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
    1
    1. scibot 22 Feb 2024
      RRID:AB_2688011

      DOI: 10.1016/j.celrep.2024.113780

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    sciencedirect.com/science/article/pii/S2211124724001086
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    Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo
    1
    1. scibot 22 Feb 2024
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2024.01.026

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    sciencedirect.com/science/article/pii/S1097276524000935
  6. Nov 2023
  7. www.sciencedirect.com www.sciencedirect.com
    Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cub.2023.10.068

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    sciencedirect.com/science/article/abs/pii/S0960982223015063
  8. Sep 2023
  9. www.sciencedirect.com www.sciencedirect.com
    A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.devcel.2023.08.031

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    sciencedirect.com/science/article/pii/S1534580723004586
  10. Aug 2023
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for measuring BRAF autoinhibition in live cells using a proximity-based NanoBRET assay
    1
    1. scibot 26 Aug 2023
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      DOI: 10.1016/j.xpro.2023.102461

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    ncbi.nlm.nih.gov/pmc/articles/PMC10440347/
  12. www.sciencedirect.com www.sciencedirect.com
    Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
    1
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.chembiol.2023.07.006

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    sciencedirect.com/science/article/pii/S2451945623002337
  13. Jul 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Different chromatin-scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2
    2
    1. scibot 08 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112748

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    2. scibot 08 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112748

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    sciencedirect.com/science/article/pii/S2211124723007593
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    Oncogenic K-Ras suppresses global miRNA function
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.molcel.2023.06.008

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    sciencedirect.com/science/article/pii/S109727652300429X
  16. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
    1
    1. scibot 01 Jul 2023
      RRID:AB_2688011

      DOI: 10.1016/j.celrep.2023.112721

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    sciencedirect.com/science/article/pii/S2211124723007325
  17. May 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
    1
    1. scibot 19 May 2023
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2023.04.021

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    sciencedirect.com/science/article/pii/S1097276523002927
  19. Mar 2023
  20. www.sciencedirect.com www.sciencedirect.com
    FAM193A is a positive regulator of p53 activity
    1
    1. scibot 10 Mar 2023
      AB_2688011

      DOI: 10.1016/j.celrep.2023.112230

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    sciencedirect.com/science/article/pii/S2211124723002413
  21. link.springer.com link.springer.com
    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
    1
    1. scibot 08 Mar 2023
      RRID:AB_2688011

      DOI: 10.1007/s12035-023-03281-3

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    link.springer.com/article/10.1007/s12035-023-03281-3
  22. Feb 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
    1
    1. scibot 17 Feb 2023
      RRID:AB_2688011

      DOI: 10.1126/sciadv.adg2997

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    ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
  24. Jan 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation
    1
    1. scibot 26 Jan 2023
      RRID:AB_2688011

      DOI: 10.1016/j.jcmgh.2022.10.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC9868690/
  26. Nov 2022
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanisms governing target search and binding dynamics of hypoxia-inducible factors
    1
    1. scibot 30 Nov 2022
      Promega, Madison, WI, #G9211

      DOI: 10.7554/eLife.75064

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
  28. www.sciencedirect.com www.sciencedirect.com
    RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
    1
    1. scibot 11 Nov 2022
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2022.10.016

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    sciencedirect.com/science/article/pii/S1097276522010164
  29. www.sciencedirect.com www.sciencedirect.com
    Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci
    1
    1. scibot 03 Nov 2022
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2022.10.004

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    sciencedirect.com/science/article/pii/S1097276522009613
  30. Oct 2022
  31. www.sciencedirect.com www.sciencedirect.com
    A brain atlas of synapse protein lifetime across the mouse lifespan
    1
    1. scibot 06 Oct 2022
      RRID:AB_2688011

      DOI: 10.1016/j.neuron.2022.09.009

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    sciencedirect.com/science/article/pii/S0896627322008145
  32. Sep 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct regions of H. pylori’s bactofilin CcmA regulate protein–protein interactions to control helical cell shape
    1
    1. scibot 27 Sep 2022
      RRID:AB_2688011

      DOI: 10.7554/eLife.80111

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    ncbi.nlm.nih.gov/pmc/articles/PMC9507126/
  34. Feb 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribose) drives condensation of FUS via a transient interaction
    1
    1. scibot 23 Feb 2022
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2022.01.018

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    sciencedirect.com/science/article/pii/S1097276522000612
  36. Nov 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
    1
    1. scibot 30 Nov 2021
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2021.11.004

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    sciencedirect.com/science/article/pii/S1097276521009540
  38. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
    1
    1. scibot 19 Nov 2021
      RRID:AB_2688011

      DOI: 10.1016/j.neuron.2021.10.036

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    sciencedirect.com/science/article/pii/S0896627321008667
  39. www.jneurosci.org www.jneurosci.org
    Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism
    1
    1. scibot 13 Nov 2021
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      DOI: 10.1523/JNEUROSCI.1914-20.2021

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    jneurosci.org/content/41/45/9431
  40. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn
    1
    1. scibot 09 Nov 2021
      RRID:AB_2688011

      DOI: 10.1096/fj.202101035RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101035RR
  41. Sep 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons
    1
    1. scibot 25 Sep 2021
      RRID:AB_2688011

      DOI: 10.7554/eLife.67261

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    ncbi.nlm.nih.gov/pmc/articles/PMC8452306/
  43. May 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Processive Activity of Replicative DNA Polymerases in the Replisome of Live Eukaryotic Cells
    1
    1. scibot 07 May 2021
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2020.08.014

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    sciencedirect.com/science/article/pii/S1097276520305773
  45. www.sciencedirect.com www.sciencedirect.com
    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.08.006

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    sciencedirect.com/science/article/pii/S1534580720306304
  46. Apr 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras
    1
    1. scibot 09 Apr 2021
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      DOI: 10.1016/j.chembiol.2021.03.011

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    sciencedirect.com/science/article/pii/S2451945621001501
  48. Mar 2021
  49. www.sciencedirect.com www.sciencedirect.com
    PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
    1
    1. scibot 22 Mar 2021
      RRID:AB_2688011

      DOI: 10.1016/j.molcel.2021.01.015

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    sciencedirect.com/science/article/pii/S1097276521000150
  50. Feb 2021
  51. www.cell.com www.cell.com
    Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo
    1
    1. scibot 24 Feb 2021
      RRID:AB_2688011

      DOI: 10.1016/j.celrep.2019.12.101

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    cell.com/cell-reports/abstract/S2211-1247(19)31766-8
  52. Sep 2020
  53. www.sciencedirect.com www.sciencedirect.com
    YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways
    1
    1. scibot 11 Sep 2020
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      DOI: 10.1016/j.celrep.2020.108120

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    sciencedirect.com/science/article/pii/S2211124720311098
  54. www.sciencedirect.com www.sciencedirect.com
    High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down
    1
    1. scibot 07 Sep 2020
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      DOI: 10.1016/j.molcel.2020.05.009

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    sciencedirect.com/science/article/pii/S1097276520303105
  55. Jan 2020
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determining cellular CTCF and cohesin abundances to constrain 3D genome models
    1
    1. scibot 13 Jan 2020
      RRID:AB_2688011

      DOI: 10.7554/eLife.40164

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    ncbi.nlm.nih.gov/pmc/articles/PMC6579579/
  57. www.sciencedirect.com www.sciencedirect.com
    Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.07.039

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    sciencedirect.com/science/article/pii/S1097276519305945
  58. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2688011

      DOI: 10.1016/j.immuni.2019.02.009

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    sciencedirect.com/science/article/pii/S1074761319300755
  59. Nov 2018
  60. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S2451945618302320