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CBP-IDRs regulate acetylation and gene expression

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1. scibot 13 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117109
  
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sciencedirect.com/science/article/pii/S2211124726001877
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A cellular basis for the mammalian nocturnal-diurnal switch

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1. scibot 11 Mar 2026
  
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  DOI: 10.1126/science.ady2822
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618833/
Mar 2026
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Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes

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1. scibot 05 Mar 2026
  
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  DOI: 10.1016/j.molcel.2026.02.009
  
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sciencedirect.com/science/article/pii/S1097276526001048
Jan 2026
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Establishing synthetic ribbon-type active zones in a heterologous expression system

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1. scibot 15 Jan 2026
  
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  DOI: 10.7554/eLife.98254
  
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elifesciences.org/articles/98254
Dec 2025
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ARAP2 regulates responses to interferon-gamma by restricting SOCS1

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1. scibot 16 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116667
  
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sciencedirect.com:5037/science/article/pii/S2211124725014391
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Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.devcel.2025.11.001
  
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sciencedirect.com:5037/science/article/pii/S1534580725006938
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Recruitment of FBXO22 for targeted degradation of NSD2

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1. scibot 02 Dec 2025
  
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  DOI: 10.1038/s41589-024-01660-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11581931/
Sep 2025
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A role for CASM in the repair of damaged Golgi architecture

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1. scibot 20 Sep 2025
  
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  DOI: 10.1101/2025.09.04.674289
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12424704/
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Coordination of autophagosome closure and release by the Alzheimer’s disease-associated protein BIN1

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116266
  
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sciencedirect.com/science/article/pii/S221112472501037X
Jul 2025
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BPS Publications

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1. scibot 11 Jul 2025
  
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  DOI: 10.1111/bph.70094
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70094
Jun 2025
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Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.chembiol.2025.05.012
  
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sciencedirect.com/science/article/pii/S2451945625001734
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PDF-html.html

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1. scibot 12 Jun 2025
  
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  DOI: 10.1158/0008-5472.can-24-3785
  
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52.53.155.43/6d05284590fa38103d7fbc1633c815ab1c347fcd/PDF-html.html
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The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1

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1. scibot 11 Jun 2025
  
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  DOI: 10.1083/jcb.202411078
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12135873/
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Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.chembiol.2025.05.005
  
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sciencedirect.com/science/article/pii/S2451945625001667
Apr 2025
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Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.04.002
  
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sciencedirect.com/science/article/pii/S1097276525003053
Jan 2025
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Ca2+/calmodulin-dependent protein kinase II β decodes ER Ca2+ transients to trigger autophagosome formation

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.molcel.2024.12.005
  
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sciencedirect.com/science/article/pii/S1097276524010001
Sep 2024
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The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization

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1. scibot 13 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114689
  
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sciencedirect.com/science/article/pii/S2211124724010404
Aug 2024
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Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.chembiol.2024.07.005
  
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sciencedirect.com/science/article/pii/S2451945624003076
Jun 2024
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Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.devcel.2024.04.020
  
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sciencedirect.com/science/article/pii/S1534580724002958
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N-terminal tagging of RNA Polymerase II shapes transcriptomes more than C-terminal alterations

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1. scibot 08 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.109914
  
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sciencedirect.com/science/article/pii/S2589004224011362
Apr 2024
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Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB

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1. scibot 26 Apr 2024
  
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  DOI: 10.1016/j.cell.2024.03.022
  
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sciencedirect.com/science/article/pii/S0092867424003131
Feb 2024
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In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux

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1. scibot 22 Feb 2024
  
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Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo

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1. scibot 22 Feb 2024
  
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  DOI: 10.1016/j.molcel.2024.01.026
  
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sciencedirect.com/science/article/pii/S1097276524000935
Nov 2023
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Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.cub.2023.10.068
  
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sciencedirect.com/science/article/abs/pii/S0960982223015063
Sep 2023
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A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.devcel.2023.08.031
  
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sciencedirect.com/science/article/pii/S1534580723004586
Aug 2023
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Protocol for measuring BRAF autoinhibition in live cells using a proximity-based NanoBRET assay

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1. scibot 26 Aug 2023
  
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  DOI: 10.1016/j.xpro.2023.102461
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10440347/
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Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3

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1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.chembiol.2023.07.006
  
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sciencedirect.com/science/article/pii/S2451945623002337
Jul 2023
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Different chromatin-scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2

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1. scibot 08 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112748
  
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  DOI: 10.1016/j.celrep.2023.112748
  
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sciencedirect.com/science/article/pii/S2211124723007593
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Oncogenic K-Ras suppresses global miRNA function

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  DOI: 10.1016/j.molcel.2023.06.008
  
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sciencedirect.com/science/article/pii/S109727652300429X
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Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway

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1. scibot 01 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112721
  
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sciencedirect.com/science/article/pii/S2211124723007325
May 2023
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Unconventional initiation of PINK1/Parkin mitophagy by Optineurin

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1. scibot 19 May 2023
  
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  DOI: 10.1016/j.molcel.2023.04.021
  
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sciencedirect.com/science/article/pii/S1097276523002927
Mar 2023
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FAM193A is a positive regulator of p53 activity

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1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112230
  
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sciencedirect.com/science/article/pii/S2211124723002413
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Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons

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1. scibot 08 Mar 2023
  
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  DOI: 10.1007/s12035-023-03281-3
  
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link.springer.com/article/10.1007/s12035-023-03281-3
Feb 2023
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Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation

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1. scibot 17 Feb 2023
  
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  DOI: 10.1126/sciadv.adg2997
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
Jan 2023
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Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation

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1. scibot 26 Jan 2023
  
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  DOI: 10.1016/j.jcmgh.2022.10.008
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9868690/
Nov 2022
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Mechanisms governing target search and binding dynamics of hypoxia-inducible factors

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1. scibot 30 Nov 2022
  
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  Promega, Madison, WI, #G9211
  
  DOI: 10.7554/eLife.75064
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
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RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation

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1. scibot 11 Nov 2022
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2022.10.016
  
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sciencedirect.com/science/article/pii/S1097276522010164
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Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci

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1. scibot 03 Nov 2022
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2022.10.004
  
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sciencedirect.com/science/article/pii/S1097276522009613
Oct 2022
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A brain atlas of synapse protein lifetime across the mouse lifespan

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1. scibot 06 Oct 2022
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.neuron.2022.09.009
  
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sciencedirect.com/science/article/pii/S0896627322008145
Sep 2022
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Distinct regions of H. pylori’s bactofilin CcmA regulate protein–protein interactions to control helical cell shape

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1. scibot 27 Sep 2022
  
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  RRID:AB_2688011
  
  DOI: 10.7554/eLife.80111
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9507126/
Feb 2022
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Poly(ADP-ribose) drives condensation of FUS via a transient interaction

1
1. scibot 23 Feb 2022
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2022.01.018
  
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sciencedirect.com/science/article/pii/S1097276522000612
Nov 2021
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Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery

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1. scibot 30 Nov 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2021.11.004
  
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Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

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1. scibot 19 Nov 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.neuron.2021.10.036
  
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sciencedirect.com/science/article/pii/S0896627321008667
www.jneurosci.org www.jneurosci.org

Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism

1
1. scibot 13 Nov 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1523/JNEUROSCI.1914-20.2021
  
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jneurosci.org/content/41/45/9431
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn

1
1. scibot 09 Nov 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1096/fj.202101035RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101035RR
Sep 2021
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Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

1
1. scibot 25 Sep 2021
  
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  RRID:AB_2688011
  
  DOI: 10.7554/eLife.67261
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8452306/
May 2021
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Processive Activity of Replicative DNA Polymerases in the Replisome of Live Eukaryotic Cells

1
1. scibot 07 May 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2020.08.014
  
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sciencedirect.com/science/article/pii/S1097276520305773
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The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction

1
1. scibot 05 May 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.devcel.2020.08.006
  
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sciencedirect.com/science/article/pii/S1534580720306304
Apr 2021
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Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras

1
1. scibot 09 Apr 2021
  
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  AB_2688011
  
  DOI: 10.1016/j.chembiol.2021.03.011
  
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sciencedirect.com/science/article/pii/S2451945621001501
Mar 2021
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PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells

1
1. scibot 22 Mar 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2021.01.015
  
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sciencedirect.com/science/article/pii/S1097276521000150
Feb 2021
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Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo

1
1. scibot 24 Feb 2021
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.celrep.2019.12.101
  
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cell.com/cell-reports/abstract/S2211-1247(19)31766-8
Sep 2020
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YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways

1
1. scibot 11 Sep 2020
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.celrep.2020.108120
  
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sciencedirect.com/science/article/pii/S2211124720311098
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High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down

1
1. scibot 07 Sep 2020
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2020.05.009
  
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sciencedirect.com/science/article/pii/S1097276520303105
Jan 2020
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Determining cellular CTCF and cohesin abundances to constrain 3D genome models

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1. scibot 13 Jan 2020
  
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  RRID:AB_2688011
  
  DOI: 10.7554/eLife.40164
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6579579/
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Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2688011
  
  DOI: 10.1016/j.molcel.2019.07.039
  
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cell.com/molecular-cell/fulltext/S1097-2765(19)30594-5
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Untitled document

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  RRID:AB_2688011
  
  DOI: 10.1016/j.immuni.2019.02.009
  
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sciencedirect.com/science/article/pii/S1074761319300755
Nov 2018
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Untitled document

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sciencedirect.com/science/article/pii/S2451945618302320