41 Matching Annotations
  1. Last 7 days
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    Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
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    sciencedirect.com/science/article/pii/S2451945624003076
  3. Jun 2024
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    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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    sciencedirect.com/science/article/pii/S1534580724002958
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    N-terminal tagging of RNA Polymerase II shapes transcriptomes more than C-terminal alterations
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    sciencedirect.com/science/article/pii/S2589004224011362
  6. Apr 2024
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    sciencedirect.com/science/article/pii/S0092867424003131
  8. Feb 2024
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    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    sciencedirect.com/science/article/pii/S2211124724001086
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    Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo
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    sciencedirect.com/science/article/pii/S1097276524000935
  11. Nov 2023
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    Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
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    sciencedirect.com/science/article/abs/pii/S0960982223015063
  13. Sep 2023
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    A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans
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    sciencedirect.com/science/article/pii/S1534580723004586
  15. Aug 2023
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    Protocol for measuring BRAF autoinhibition in live cells using a proximity-based NanoBRET assay
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      DOI: 10.1016/j.xpro.2023.102461

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    ncbi.nlm.nih.gov/pmc/articles/PMC10440347/
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    Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
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    1. scibot 17 Aug 2023
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    sciencedirect.com/science/article/pii/S2451945623002337
  18. Jul 2023
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    Different chromatin-scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2
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    sciencedirect.com/science/article/pii/S2211124723007593
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    Oncogenic K-Ras suppresses global miRNA function
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    sciencedirect.com/science/article/pii/S109727652300429X
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    Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
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    sciencedirect.com/science/article/pii/S2211124723007325
  22. May 2023
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    Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
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    1. scibot 19 May 2023
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      DOI: 10.1016/j.molcel.2023.04.021

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    sciencedirect.com/science/article/pii/S1097276523002927
  24. Mar 2023
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    FAM193A is a positive regulator of p53 activity
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    sciencedirect.com/science/article/pii/S2211124723002413
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    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
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      DOI: 10.1007/s12035-023-03281-3

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    link.springer.com/article/10.1007/s12035-023-03281-3
  27. Feb 2023
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    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
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      DOI: 10.1126/sciadv.adg2997

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    ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
  29. Jan 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9868690/
  31. Nov 2022
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    Mechanisms governing target search and binding dynamics of hypoxia-inducible factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
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    RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
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    sciencedirect.com/science/article/pii/S1097276522010164
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    Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci
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    sciencedirect.com/science/article/pii/S1097276522009613
  35. Oct 2022
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    A brain atlas of synapse protein lifetime across the mouse lifespan
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    sciencedirect.com/science/article/pii/S0896627322008145
  37. Sep 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct regions of H. pylori’s bactofilin CcmA regulate protein–protein interactions to control helical cell shape
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    ncbi.nlm.nih.gov/pmc/articles/PMC9507126/
  39. Feb 2022
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    Poly(ADP-ribose) drives condensation of FUS via a transient interaction
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    sciencedirect.com/science/article/pii/S1097276522000612
  41. Nov 2021
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    Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
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    sciencedirect.com/science/article/pii/S1097276521009540
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    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
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    sciencedirect.com/science/article/pii/S0896627321008667
  44. www.jneurosci.org www.jneurosci.org
    Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism
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      DOI: 10.1523/JNEUROSCI.1914-20.2021

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    jneurosci.org/content/41/45/9431
  45. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn
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      DOI: 10.1096/fj.202101035RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101035RR
  46. Sep 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons
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      DOI: 10.7554/eLife.67261

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    ncbi.nlm.nih.gov/pmc/articles/PMC8452306/
  48. May 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Processive Activity of Replicative DNA Polymerases in the Replisome of Live Eukaryotic Cells
    1
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      DOI: 10.1016/j.molcel.2020.08.014

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    sciencedirect.com/science/article/pii/S1097276520305773
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    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
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      DOI: 10.1016/j.devcel.2020.08.006

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    sciencedirect.com/science/article/pii/S1534580720306304
  51. Apr 2021
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    Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras
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    sciencedirect.com/science/article/pii/S2451945621001501
  53. Mar 2021
  54. www.sciencedirect.com www.sciencedirect.com
    PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
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      DOI: 10.1016/j.molcel.2021.01.015

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    sciencedirect.com/science/article/pii/S1097276521000150
  55. Feb 2021
  56. www.cell.com www.cell.com
    Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo
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      DOI: 10.1016/j.celrep.2019.12.101

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    cell.com/cell-reports/abstract/S2211-1247(19)31766-8
  57. Sep 2020
  58. www.sciencedirect.com www.sciencedirect.com
    YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways
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      DOI: 10.1016/j.celrep.2020.108120

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    sciencedirect.com/science/article/pii/S2211124720311098
  59. www.sciencedirect.com www.sciencedirect.com
    High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down
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      DOI: 10.1016/j.molcel.2020.05.009

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    sciencedirect.com/science/article/pii/S1097276520303105
  60. Jan 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determining cellular CTCF and cohesin abundances to constrain 3D genome models
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      DOI: 10.7554/eLife.40164

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    ncbi.nlm.nih.gov/pmc/articles/PMC6579579/
  62. www.sciencedirect.com www.sciencedirect.com
    Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF
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      DOI: 10.1016/j.molcel.2019.07.039

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    sciencedirect.com/science/article/pii/S1097276519305945
  63. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_2688011

      DOI: 10.1016/j.immuni.2019.02.009

      Resource: (Promega Cat# G9211, RRID:AB_2688011)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2688011

      What is this?

      RRID:AB_2688011 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319300755
  64. Nov 2018
  65. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 05 Nov 2018
      RRID:AB_2688011

      Resource used:

      (Promega Cat# G9211, RRID:AB_2688011)

      SciCrunch record: RRID:AB_2688011

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2688011
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    sciencedirect.com/science/article/pii/S2451945618302320