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The AMPK-ALDH7A1 axis drives metabolic reprogramming and anti-tumor immunity in hepatocellular carcinoma via KDM5C inhibition

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.devcel.2026.10.006
  
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sciencedirect.com/science/article/pii/S1534580726003928
Jul 2026
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A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death

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1. scibot 21 Jul 2026
  
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  DOI: 10.1016/j.cell.2026.06.037
  
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sciencedirect.com/science/article/pii/S0092867426007579
Feb 2026
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Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability

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1. scibot 05 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.01.005
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12995521/
Sep 2025
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Maternal CENP-C restores centromere symmetry in mammalian zygotes to ensure proper chromosome segregation

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1. scibot 25 Sep 2025
  
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  DOI: 10.1016/j.devcel.2025.08.017
  
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sciencedirect.com/science/article/pii/S1534580725005374
Dec 2024
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Spatial organizations of heterochromatin underpin nuclear structural integrity of ventricular cardiomyocytes against mechanical stress

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115048
  
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sciencedirect.com/science/article/pii/S2211124724013998
Feb 2024
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Temozolomide sensitizes ARID1A-mutated cancers to PARP inhibitors

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1. scibot 16 Feb 2024
  
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  DOI: 10.1158/0008-5472.CAN-22-3646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10527942/
Sep 2023
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can-22-3646-html.html

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1. scibot 22 Sep 2023
  
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  DOI: 10.1158/0008-5472.can-22-3646
  
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52.53.155.43/7c5c0394bd7eaeefd5e70a237f23894cb3f7190b/can-22-3646-html.html
Mar 2023
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FAM193A is a positive regulator of p53 activity

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1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112230
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10164416/
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Histone malonylation is regulated by SIRT5 and KAT2A

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1. scibot 09 Mar 2023
  
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  RRID:AB_2714167
  
  DOI: 10.1016/j.isci.2023.106193
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
Jan 2023
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ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis

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1. scibot 20 Jan 2023
  
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  DOI: 10.1126/sciadv.abq3951
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9821869/
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ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis

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1. scibot 12 Jan 2023
  
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  DOI: 10.1126/sciadv.abq3951
  
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science.org/doi/10.1126/sciadv.abq3951
Dec 2022
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USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction

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1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111653
  
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sciencedirect.com/science/article/pii/S2211124722015248
Jun 2022
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The cecropin-prophenoloxidase regulatory mechanism is a cross-species physiological function in mosquitoes

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1. scibot 15 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104478
  
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sciencedirect.com/science/article/pii/S2589004222007490
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High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

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1. scibot 04 Jun 2022
  
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  DOI: 10.7554/eLife.69802
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9154743/
Jul 2021
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T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

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1. scibot 03 Jul 2021
  
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  DOI: 10.7554/eLife.67123
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8225385/
May 2021
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p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation

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1. scibot 26 May 2021
  
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  RRID:AB_2714167
  
  DOI: 10.1016/j.celrep.2021.109153
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8170441/
Apr 2021
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A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2021.02.007
  
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sciencedirect.com/science/article/pii/S2451945621000921
Sep 2020
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A Quantitative Genetic Interaction Map of HIV Infection

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.02.004
  
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sciencedirect.com/science/article/pii/S1097276520300745
Jan 2020
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Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.10.044
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7175411/
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Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.08.019
  
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sciencedirect.com/science/article/pii/S1097276519306586
Nov 2018
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The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1550413118303905