56 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy
    1
    1. scibot 11 Dec 2024
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      DOI: 10.1038/s44319-024-00271-x

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    pmc.ncbi.nlm.nih.gov/articles/PMC11624267/
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Vitamin D alleviates HFD-induced hepatic fibrosis by inhibiting DNMT1 to affect the TGFβ1/Smad3 pathway
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    1. scibot 15 Nov 2024
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    sciencedirect.com/science/article/pii/S2589004224024878
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Arctiin Alleviates Atopic Dermatitis Against Inflammation and Pyroptosis Through Suppressing TLR4/MyD88/NF-κB and NLRP3/Caspase-1/GSDMD Signaling Pathways
    1
    1. scibot 10 Nov 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539860/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial transplantation confers protection against the effects of ischemic stroke by repressing microglial pyroptosis and promoting neurogenesis
    1
    1. scibot 07 Nov 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11467935/
  7. Oct 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
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    1. scibot 02 Oct 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11438333/
  9. Jul 2024
  10. www.sciencedirect.com www.sciencedirect.com
    TERT activation targets DNA methylation and multiple aging hallmarks
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    sciencedirect.com/science/article/pii/S0092867424005920
  11. www.nature.com www.nature.com
    Table 1 Antibody table.
    1
    1. scibot 19 Jul 2024
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  12. May 2024
  13. 52.53.155.43 52.53.155.43
    mcr-23-0478-html.html
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  14. Apr 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of DNA methylation/demethylation with the functional outcome of stroke in a hyperinflammatory state
    1
    1. scibot 24 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034580/
  16. 52.53.155.43 52.53.155.43
    mcr-23-0478-html.html
    1
    1. scibot 19 Apr 2024
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  17. Mar 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
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    1. scibot 29 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724003267
  19. Jan 2024
  20. dx.doi.org dx.doi.org
    cwad087-html.html
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    1. scibot 11 Jan 2024
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  21. Dec 2023
  22. www.sciencedirect.com www.sciencedirect.com
    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
    2
    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.molcel.2023.11.015

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      DOI: 10.1016/j.molcel.2023.11.015

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    sciencedirect.com/science/article/pii/S1097276523009607
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage IL-1β-positive microvesicles exhibit thrombo-inflammatory properties and are detectable in patients with active juvenile idiopathic arthritis
    1
    1. scibot 10 Dec 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10703381/
  24. Nov 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
    1
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      DOI: 10.1186/s40779-023-00494-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
  26. dx.doi.org dx.doi.org
    cwad087-html.html
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    1. scibot 10 Nov 2023
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  27. Oct 2023
  28. www.sciencedirect.com www.sciencedirect.com
    HDL inhibits pancreatic acinar cell NLRP3 inflammasome activation and protect against acinar cell pyroptosis in acute pancreatitis
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.intimp.2023.110950

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    sciencedirect.com/science/article/pii/S1567576923012754
  29. Sep 2023
  30. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Horie-html.html
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      DOI: 10.1002/1878-0261.13524

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      DOI: 10.1002/1878-0261.13524

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    52.53.155.43/b5e8e877c627d157950951119edc64db79086ad6/Molecular Oncology - 2023 - Horie-html.html
  31. Aug 2023
  32. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    HIF-1α inhibition in macrophages preserves acute liver failure by reducing IL-1β production
    1
    1. scibot 29 Aug 2023
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      DOI: 10.1096/fj.202300428RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202300428RR
  33. May 2023
  34. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
    1
    1. scibot 31 May 2023
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    sciencedirect.com/science/article/pii/S1097276523003350
  35. Mar 2023
  36. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
    1
    1. scibot 17 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112265

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    pubmed.ncbi.nlm.nih.gov/36930645/
  37. Jan 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
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      DOI: 10.1016/j.molcel.2022.12.002

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    sciencedirect.com/science/article/pii/S1097276522011376
  39. Dec 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
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      DOI: 10.1016/j.celrep.2022.111742

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    sciencedirect.com/science/article/pii/S2211124722016205
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice
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    1. scibot 03 Dec 2022
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      DOI: 10.3389/fphar.2022.1020670

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    ncbi.nlm.nih.gov/pmc/articles/PMC9714675/
  42. Nov 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Commensal cow Roseburia reduces gut-dysbiosis-induced mastitis through inhibiting bacterial translocation by producing butyrate in mice
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    1. scibot 24 Nov 2022
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    sciencedirect.com/science/article/pii/S2211124722015558
  44. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 19 Nov 2022
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      DOI: 10.1111/bph.15949

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15949
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection
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    1. scibot 04 Nov 2022
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      DOI: 10.1084/jem.20220837

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    ncbi.nlm.nih.gov/pmc/articles/PMC9623368/
  46. Jun 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124722007896
  48. www.sciencedirect.com www.sciencedirect.com
    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
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      DOI: 10.1016/j.neuron.2022.05.009

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    sciencedirect.com/science/article/pii/S0896627322004500
  49. Apr 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 1 cellular localization regulates the metabolic fate of glucose
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    sciencedirect.com/science/article/pii/S1097276522001666
  51. Mar 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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    sciencedirect.com/science/article/pii/S2211124722002492
  53. Feb 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Macrophage IL-1β promotes arteriogenesis by autocrine STAT3- and NF-κB-mediated transcription of pro-angiogenic VEGF-A
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    sciencedirect.com/science/article/pii/S2211124722000213
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC7897256/
  56. Dec 2021
  57. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15720
  58. Sep 2021
  59. www.nature.com www.nature.com
    Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation
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    nature.com/articles/s41401-021-00754-w
  60. Aug 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
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      DOI: 10.1016/j.cell.2021.07.026

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    sciencedirect.com/science/article/pii/S0092867421008850
  62. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.celrep.2018.09.071

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    sciencedirect.com/science/article/pii/S2211124718315316
  63. Jul 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      RRID:AB_2715503

      DOI: 10.1016/j.molcel.2018.11.018

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      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC6372082/
  65. www.sciencedirect.com www.sciencedirect.com
    β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression
    1
    1. scibot 21 Jul 2021
      RRID:AB_2715503

      DOI: 10.1016/j.immuni.2021.07.002

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

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    sciencedirect.com/science/article/pii/S1074761321002648
  66. Jun 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways
    1
    1. scibot 18 Jun 2021
      RRID:AB_2715503

      DOI: 10.1016/j.isci.2021.102498

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8188380/
  68. Apr 2021
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic activation of spinal microglia triggers chronic pain in mice
    1
    1. scibot 10 Apr 2021
      RRID:AB_2715503

      DOI: 10.1371/journal.pbio.3001154

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @evieth

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      RRID:AB_2715503 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC8011727/
  70. Feb 2021
  71. www.cell.com www.cell.com
    Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation
    1
    1. scibot 24 Feb 2021
      RRID:AB_2715503

      DOI: 10.1016/j.chom.2020.07.019

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      Curator: @Naa003

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    cell.com/cell-host-microbe/fulltext/S1931-3128(20)30422-4
  72. Jan 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation
    1
    1. scibot 21 Jan 2021
      RRID:AB_2715503

      DOI: 10.1016/j.ccell.2020.12.012

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @Naa003

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      RRID:AB_2715503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610820306607
  74. Sep 2020
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 13 Sep 2020
      RRID:AB_2715503

      DOI: 10.1111/bph.15182

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

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      RRID:AB_2715503 RRIDCUR:Validated
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15182
  76. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 04 Sep 2020
      RRID:AB_2715503

      DOI: 10.1111/bph.15026

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2715503

      Curator comments: IL-1β (3A6) Mouse mAb antibody Cell Signaling Technology Cat# 12242

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15026
  77. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Astaxanthin attenuates hepatic damages and mitochondrial dysfunction in nonalcoholic fatty liver disease by up‐regulating the FGF21/PGC‐1α pathway
    1
    1. scibot 04 Sep 2020
      AB_2715503

      DOI: 10.1111/bph.15099

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:AB_2715503
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15099
  78. May 2020
  79. link.springer.com link.springer.com
    Distribution of IL-1β immunoreactive cells in pancreatic biopsies from living volunteers with new-onset type 1 diabetes: comparison with donors without diabetes and with longer duration of disease
    1
    1. nPOD_Curator 15 May 2020
      The immunohistochemical specificity of anti-IL-1β (catalogue no. 12242; Cell Signaling Technology) has been validated by the manufacturer. Thus, by immunohistochemistry, it successfully detects IL-1β immunoreactive cells in human colonic sections from individuals with chronic colitis. Further, by western blotting, the same antibody detects mature recombinant human and mouse IL-1β and the human precursor (molecular mass of 34 kDa) in extracts of Raw 264.7 and human monocyte-derived THP-1 cells, following exposure to Brefeldin and lipopolysaccharide (LPS), respectively. Anti-IL-1β was replaced with diluent to act as negative controls. As further controls, paraffin sections of THP-1 cells, harvested after incubation with LPS (100 ng/ml for 3 h) and without (from Cell Signaling Technology), were evaluated in this laboratory for IL-1β immunohistochemical specificity. The immunostaining protocol for IL-1β was tested with formalin-fixed tonsil sections, supplied by Department of Surgery, University of Auckland. Sections from selected pancreas and tonsil were immunostained for IL-1β in two separate sections. They were then exposed to rabbit anti-CD68 or rabbit anti-CD3, followed by donkey anti-rabbit IgG-biotin and then streptavidin–Alexa 568. Pancreatic sections were immunostained subsequently for insulin as above, followed by donkey anti-guinea pig IgG–Alexa 488.

      IHC for IL-1b

      obiwan:Method PMID:29589071 RRID:AB_2715503
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    link.springer.com/article/10.1007/s00125-018-4600-8
  80. Jan 2020
  81. iovs.arvojournals.org iovs.arvojournals.org
    Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal
    1
    1. scibot 13 Jan 2020
      RRID:AB_2715503

      DOI: 10.1167/iovs.18-26360

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @ethanbadger

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      RRID:AB_2715503 RRIDCUR:Validated
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    iovs.arvojournals.org/article.aspx
  82. www.sciencedirect.com www.sciencedirect.com
    Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2715503

      DOI: 10.1016/j.celrep.2019.05.015

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @ethanbadger

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      RRID:AB_2715503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719306266
  83. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2715503

      DOI: 10.1016/j.molcel.2018.11.018

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @evieth

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      RRID:AB_2715503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518309882
  84. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Inactivation of endothelial adenosine A2A receptors protects mice from cerebral ischaemia‐induced brain injury
    1
    1. scibot 13 Jan 2020
      RRID:AB_2715503

      DOI: 10.1111/bph.14673

      Resource: (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      Curator: @Naa003

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      RRID:AB_2715503 RRIDCUR:Validated
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14673
  85. Nov 2018
  86. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
    1
    1. scibot 05 Nov 2018
      RRID:AB_2715503

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      SciCrunch record: RRID:AB_2715503

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2715503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761318303844
  87. Nov 2017
  88. www.sciencedirect.com www.sciencedirect.com
    NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
    1
    1. scibot 08 Nov 2017
      12242

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 12242, RRID:AB_2715503)

      SciCrunch record: RRID:AB_2715503

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2715503 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276517306147