80 Matching Annotations
  1. Last 7 days
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    CircEZH2 Promotes Gallbladder Cancer Progression and Lipid Metabolism Reprogramming through the miR-556-5p/SCD1 Axis
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    sciencedirect.com/science/article/pii/S2589004224016535
  3. Mar 2024
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    A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960274/
  5. Feb 2024
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    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
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    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
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    Sleep fragmentation induces heart failure in a hypertrophic cardiomyopathy mouse model by altering redox metabolism
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    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells
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    Genome-wide p63-target gene analyses reveal TAp63/NRF2-dependent oxidative stress responses
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    1. scibot 03 Feb 2024
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  12. Jan 2024
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    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
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    1. scibot 11 Jan 2024
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    sciencedirect.com/science/article/pii/S1550413123004655
  14. Nov 2023
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    Stress-induced β cell early senescence confers protection against type 1 diabetes
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    sciencedirect.com/science/article/pii/S1550413123003832
  16. Oct 2023
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    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
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    Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
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    1. scibot 13 Oct 2023
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  19. Sep 2023
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    Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training
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    sciencedirect.com/science/article/pii/S2213231723002744
  21. Aug 2023
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    4-Octyl itaconate restricts STING activation by blocking its palmitoylation
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  23. Jul 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
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  25. 52.53.155.43 52.53.155.43
    A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
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    Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism
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    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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  28. Jun 2023
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    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
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    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
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      DOI: 10.3390/antiox12061303

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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
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      DOI: 10.1158/0008-5472.CAN-22-3848

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    Investigating the effects of 7-ketocholesterol on retinal pigment epithelium bioenergetics
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  33. May 2023
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    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    Ubiquitin-independent proteasomal degradation driven by C-degron pathways
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    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of NADPH oxidase 4 reduces mitochondrial... : Neural Regeneration Research
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    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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  39. Apr 2023
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    Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing
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  41. Mar 2023
  42. 52.53.155.43 52.53.155.43
    Inhibiting tau protein improves the recovery of spinal cord ... : Neural Regeneration Research
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  43. Feb 2023
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    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
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  45. Dec 2022
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    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
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  48. Nov 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC9623505/
  50. Oct 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The protease DDI2 regulates NRF1 activation in response to cadmium toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9557025/
  52. Aug 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
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      DOI: 10.1126/sciadv.abo5633

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    ncbi.nlm.nih.gov/pmc/articles/PMC9348805/
  54. Jul 2022
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    Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress
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    sciencedirect.com/science/article/pii/S2211124722008634
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    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
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  57. May 2022
  58. www.nature.com www.nature.com
    Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
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      DOI: 10.1038/s41467-022-30363-y

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  59. Mar 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling
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    The Protective Effects of Trans-Cinnamaldehyde against D-Galactose and Aluminum Chloride-Induced Cognitive Dysfunction in Mice
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  63. Feb 2022
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    Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
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  65. Jan 2022
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    The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2
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  67. Dec 2021
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  70. Sep 2021
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  72. Aug 2021
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    A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
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    A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
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  77. Jun 2021
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    KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
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  79. May 2021
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    Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection
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    Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential
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    3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
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  87. Feb 2021
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    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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  89. Nov 2020
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    Effect of Treadmill Exercise and Trans-Cinnamaldehyde against d-Galactose- and Aluminum Chloride-Induced Cognitive Dysfunction in Mice
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    Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection
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    The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
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    Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
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    Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury
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    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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      rabbit anti-NFE2L2/Nrf2

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    HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1
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    Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways
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    Mitohormesis Primes Tumor Invasion and Metastasis
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  110. Nov 2018
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    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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      (Cell Signaling Technology Cat# 12721, RRID:AB_2715528)

      SciCrunch record: RRID:AB_2715528

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2715528
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    sciencedirect.com/science/article/pii/S153561081730555X
  114. Nov 2017
  115. www.sciencedirect.com www.sciencedirect.com
    Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
    1
    1. scibot 08 Nov 2017
      12721

      Curator: @Jmenke

      Resource used:

      (Cell Signaling Technology Cat# 12721, RRID:AB_2715528)

      SciCrunch record: RRID:AB_2715528

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2715528 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867417310474