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  1. Last 7 days
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    SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2
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    1. scibot 21 Aug 2024
      AB_2715534

      DOI: 10.1016/j.xcrm.2024.101684

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    sciencedirect.com/science/article/pii/S2666379124004051
  3. Jul 2024
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    Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells
    1
    1. scibot 31 Jul 2024
      AB_2715534

      DOI: 10.1016/j.stem.2024.07.003

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    sciencedirect.com/science/article/pii/S1934590924002534
  5. May 2024
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    An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.devcel.2024.04.018

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    sciencedirect.com/science/article/pii/S1534580724002715
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retinal metabolism displays evidence for uncoupling of glycolysis and oxidative phosphorylation via Cori-, Cahill-, and mini-Krebs-cycle
    1
    1. scibot 15 May 2024
      RRID:AB_2715534

      DOI: 10.7554/eLife.91141

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    ncbi.nlm.nih.gov/pmc/articles/PMC11090511/
  8. Apr 2024
  9. 52.53.155.43 52.53.155.43
    JNEUROSCI.1563-23.2024.full (1)-html.html
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    1. scibot 26 Apr 2024
      RRID:AB_2715534

      DOI: 10.1523/jneurosci.1563-23.2024

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    52.53.155.43/3d13c66ed91f2e0714f85e7c6a7de97c0df74a89/JNEUROSCI.1563-23.2024.full (1)-html.html
  10. Jan 2024
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    Augmentation of scleral glycolysis promotes myopia through histone lactylation
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.023

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    sciencedirect.com/science/article/pii/S1550413123004746
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.003

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    sciencedirect.com/science/article/pii/S1550413123004552
  13. May 2023
  14. www.degruyter.com www.degruyter.com
    Inhibition of heterogeneous nuclear ribonucleoproteins A1 and oxidative stress reduces glycolysis pyruvate kinase M2 in chronic thromboembolic pulmonary hypertension
    1
    1. scibot 12 May 2023
      RRID:AB_2715534

      DOI: 10.2478/jtim-2022-0051

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    degruyter.com/document/doi/10.2478/jtim-2022-0051/html
  15. Apr 2023
  16. www.nature.com www.nature.com
    The RNA-binding protein landscapes differ between mammalian organs and cultured cells
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    1. scibot 18 Apr 2023
      RRID:AB_2715534

      DOI: 10.1038/s41467-023-37494-w

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    nature.com/articles/s41467-023-37494-w
  17. www.sciencedirect.com www.sciencedirect.com
    Neurons require glucose uptake and glycolysis in vivo
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    1. scibot 07 Apr 2023
      RRID:AB_2715534

      DOI: 10.1016/j.celrep.2023.112335

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    sciencedirect.com/science/article/pii/S2211124723003467
  18. Jan 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation
    1
    1. scibot 28 Jan 2023
      RRID:AB_2715534

      DOI: 10.1016/j.celrep.2022.111897

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    sciencedirect.com/science/article/pii/S221112472201796X
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
    1
    1. scibot 12 Jan 2023
      RRID:AB_2715534

      DOI: 10.1158/0008-5472.CAN-21-2352

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    ncbi.nlm.nih.gov/pmc/articles/PMC9256808/
  21. Jul 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis
    1
    1. scibot 27 Jul 2022
      RRID:AB_2715534

      DOI: 10.1016/j.chembiol.2022.06.011

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    sciencedirect.com/science/article/pii/S2451945622002434
  23. Jun 2022
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    1. scibot 25 Jun 2022
      RRID:AB_2715534

      DOI: 10.1016/j.molcel.2022.06.005

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    sciencedirect.com/science/article/pii/S109727652200541X
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    Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.isci.2022.104447

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    sciencedirect.com/science/article/pii/S2589004222007180
  26. Mar 2022
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    Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease
    1
    1. scibot 27 Mar 2022
      RRID:AB_2715534

      DOI: 10.1016/j.cmet.2022.02.013

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    sciencedirect.com/science/article/pii/S1550413122000857
  28. Feb 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Pyruvate Kinase M2 phosphorylation reverses aggressive cancer phenotypes
    1
    1. scibot 16 Feb 2022
      RRID:AB_2715534

      DOI: 10.1158/0008-5472.CAN-20-4190

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    ncbi.nlm.nih.gov/pmc/articles/PMC8373815/
  30. Oct 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy
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    1. scibot 26 Oct 2021
      RRID:AB_2715534

      DOI: 10.1016/j.molcel.2021.10.001

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    sciencedirect.com/science/article/pii/S1097276521008005
  32. Jun 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Oncogene-regulated release of extracellular vesicles
    1
    1. scibot 12 Jun 2021
      RRID:AB_2715534

      DOI: 10.1016/j.devcel.2021.05.014

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    sciencedirect.com/science/article/pii/S1534580721004433
  34. Feb 2021
  35. academic.oup.com academic.oup.com
    LncRNA-Malat1 is involved in lipotoxicity-induced β-cell dysfunction and the therapeutic effect of exendin-4 via Ptbp1
    1
    1. scibot 25 Feb 2021
      RRID:AB_2715534

      DOI: 10.1210/endocr/bqaa065

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    academic.oup.com/endo/article/161/7/bqaa065/5824261
  36. Oct 2020
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKM2 Determines Myofiber Hypertrophy In Vitro and Increases in Response to Resistance Exercise in Human Skeletal Muscle
    1
    1. scibot 31 Oct 2020
      RRID:AB_2715534

      DOI: 10.3390/ijms21197062

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    ncbi.nlm.nih.gov/pmc/articles/PMC7583908/
  38. Sep 2020
  39. www.sciencedirect.com www.sciencedirect.com
    Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway
    1
    1. scibot 23 Sep 2020
      RRID:AB_2715534

      DOI: 10.1016/j.celrep.2020.01.037

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    sciencedirect.com/science/article/pii/S2211124720300528
  40. Jan 2020
  41. www.sciencedirect.com www.sciencedirect.com
    Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA
    1
    1. scibot 13 Jan 2020
      RRID:AB_2715534

      DOI: 10.1016/j.chembiol.2019.11.010

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    sciencedirect.com/science/article/pii/S2451945619303927
  42. www.sciencedirect.com www.sciencedirect.com
    Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2715534

      DOI: 10.1016/j.cmet.2019.10.015

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    sciencedirect.com/science/article/pii/S1550413119306060
  43. Nov 2018
  44. www.sciencedirect.com www.sciencedirect.com
    Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
    1
    1. scibot 05 Nov 2018
      RRID:AB_2715534

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S109727651830741X
  45. Nov 2017
  46. www.sciencedirect.com www.sciencedirect.com
    MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux
    1
    1. scibot 08 Nov 2017
      7067S

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    sciencedirect.com/science/article/pii/S1934590917303363