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21 Matching Annotations

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HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis

1
1. scibot 11 Oct 2025
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.celrep.2025.116382
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
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sciencedirect.com/science/article/pii/S2211124725011532
Aug 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225017158-main-html.html

1
1. scibot 29 Aug 2025
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.isci.2025.113454
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
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52.53.155.43/d86d60ff30b3ad94317a5f54629a255673424141/1-s2.0-S2589004225017158-main-html.html
Jul 2025
www.science.org www.science.org

Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling

1
1. scibot 25 Jul 2025
  
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  AB_2721022
  
  DOI: 10.1126/science.adm9805
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:AB_2721022
  
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science.org/doi/10.1126/science.adm9805
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis

1
1. scibot 27 Feb 2025
  
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  RRID:AB_2721022
  
  DOI: 10.1038/s44318-024-00353-5
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11832924/
Dec 2024
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The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation

1
1. scibot 21 Dec 2024
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.celrep.2024.115101
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124724014529
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats

1
1. scibot 09 Mar 2024
  
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  AB_2721022
  
  DOI: 10.14814/phy2.15969
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10920058/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway

1
1. scibot 03 Feb 2024
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.isci.2024.108843
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10831937/
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease

1
1. scibot 11 Jan 2024
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.jbc.2024.105641
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0021925824000176
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Ring domains are essential for GATOR2-dependent mTORC1 activation

1
1. scibot 18 Dec 2022
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.molcel.2022.11.021
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276522011340
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells

1
1. scibot 19 Nov 2022
  
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  RRID:AB_2721022
  
  DOI: 10.1158/2767-9764.crc-22-0270
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9648415/
Sep 2022
aacrjournals.org aacrjournals.org

Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells

1
1. scibot 02 Sep 2022
  
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  RRID:AB_2721022
  
  DOI: 10.1158/2767-9764.CRC-22-0270
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2721022
  
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aacrjournals.org/cancerrescommun/article/2/8/842/708157/Na-H-exchanger-1-Enhances-Antitumor-Activity-of
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly

1
1. scibot 24 Nov 2021
  
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  RRID:AB_2721022
  
  DOI: 10.7554/eLife.71575
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2721022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
Aug 2021
academic.oup.com academic.oup.com

Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis

1
1. scibot 01 Aug 2021
  
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  AB_2721022
  
  DOI: 10.1093/biolre/ioy144
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2721022
  
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academic.oup.com/biolreprod/article/99/6/1289/5046413
May 2021
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Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity

1
1. scibot 07 May 2021
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.molcel.2020.10.004
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276520306870
www.sciencedirect.com www.sciencedirect.com

The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction

1
1. scibot 05 May 2021
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.devcel.2020.08.006
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1534580720306304
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

1
1. scibot 06 Apr 2021
  
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  RRID:AB_2721022
  
  DOI: 10.7554/eLife.63326
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2721022
  
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  RRID:AB_2721022 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7997658/
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling

1
1. scibot 22 Mar 2021
  
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  RRID:AB_2721022
  
  DOI: 10.1016/j.molcel.2021.01.009
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276521000095
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

1
1. scibot 21 Nov 2020
  
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  RRID:AB_2721022
  
  DOI: 10.7554/eLife.55994
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2721022
  
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  RRID:AB_2721022 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7661039/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR

1
1. scibot 23 Sep 2020
  
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  AB_2721022
  
  DOI: 10.1016/j.celrep.2020.107571
  
  Resource: (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2721022
  
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  RRIDCUR:Validated RRID:AB_2721022
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sciencedirect.com/science/article/pii/S2211124720305209
Nov 2018
academic.oup.com academic.oup.com

Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_2721022
  
  Resource used:
  
  (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  SciCrunch record: RRID:AB_2721022
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2721022
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academic.oup.com/biolreprod/article/99/6/1289/5046413
www.sciencedirect.com www.sciencedirect.com

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2721022
  
  Resource used:
  
  (Cell Signaling Technology Cat# 13879, RRID:AB_2721022)
  
  SciCrunch record: RRID:AB_2721022
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2721022
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sciencedirect.com/science/article/pii/S0092867418305865