41 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
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      DOI: 10.1038/s44318-024-00299-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11649786/
  3. Oct 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy
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    1. scibot 02 Oct 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433901/
  5. Sep 2024
  6. www.sciencedirect.com www.sciencedirect.com
    m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells
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      DOI: 10.1016/j.cell.2024.08.040

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    sciencedirect.com/science/article/pii/S0092867424009693
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    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
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    sciencedirect.com/science/article/pii/S1097276524007330
  8. Aug 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Epitranscriptomic reader YTHDF2 regulates SEK1(MAP2K4)-JNK-cJUN inflammatory signaling in astrocytes during neurotoxic stress
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    sciencedirect.com/science/article/pii/S2589004224018443
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    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00285-7
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anticancer effects of Erzhimaoling decoction in high-grade serous ovarian cancer in vitro and in vivo
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299366/
  12. www.cell.com www.cell.com
    METTL3 regulates cartilage development and homeostasis by affecting Lats1 mRNA stability in an m6A-YTHDF2-dependent manner
    1
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    cell.com/cell-reports/fulltext/S2211-1247(24)00864-7
  13. Jul 2024
  14. www.cell.com www.cell.com
    m6A modification inhibits miRNAs’ intracellular function, favoring their extracellular export for intercellular communication
    1
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      DOI: 10.1016/j.celrep.2024.114369

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    cell.com/cell-reports/abstract/S2211-1247(24)00697-1
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration
    1
    1. scibot 07 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11216409/
  16. May 2024
  17. www.cell.com www.cell.com
    Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation
    2
    1. scibot 03 May 2024
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    cell.com/cell-reports/fulltext/S2211-1247(24)00493-5
  18. Apr 2024
  19. www.sciencedirect.com www.sciencedirect.com
    DDX21 mediates co-transcriptional RNA m6A modification to promote transcription termination and genome stability
    2
    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1097276524001886
  20. Mar 2024
  21. www.sciencedirect.com www.sciencedirect.com
    YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113947

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    sciencedirect.com/science/article/pii/S2211124724002754
  22. Sep 2023
  23. journals.physiology.org journals.physiology.org
    Methyltransferase-like 3 facilitates the stem cell properties of esophageal cancer by upregulating patched homolog 1 via N6-methyladenosine methylation
    1
    1. scibot 14 Sep 2023
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      DOI: 10.1152/ajpcell.00136.2023

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    journals.physiology.org/doi/10.1152/ajpcell.00136.2023
  24. Aug 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder
    1
    1. scibot 09 Aug 2023
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      DOI: 10.1016/j.isci.2023.107300

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    ncbi.nlm.nih.gov/pmc/articles/PMC10405067/
  26. Jul 2023
  27. www.sciencedirect.com www.sciencedirect.com
    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
    1
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      DOI: 10.1016/j.celrep.2023.112779

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    sciencedirect.com/science/article/pii/S2211124723007908
  28. Jun 2023
  29. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
    1
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      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
  30. www.sciencedirect.com www.sciencedirect.com
    Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112704

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    sciencedirect.com/science/article/pii/S2211124723007155
  31. www.sciencedirect.com www.sciencedirect.com
    METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis
    1
    1. scibot 07 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112589

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    sciencedirect.com/science/article/pii/S2211124723006009
  32. www.sciencedirect.com www.sciencedirect.com
    Mettl3-m6A-Creb1 forms an intrinsic regulatory axis in maintaining iNKT cell pool and functional differentiation
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112584

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    sciencedirect.com/science/article/pii/S2211124723005958
  33. Dec 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina
    1
    1. scibot 06 Dec 2022
      RRID:AB_2721254

      DOI: 10.7554/eLife.79994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9718531/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TWIK-related acid-sensitive K+ channel 2 promotes renal fibrosis by inducing cell cycle arrest
    1
    1. scibot 03 Dec 2022
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      DOI: 10.1016/j.isci.2022.105620

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    ncbi.nlm.nih.gov/pmc/articles/PMC9712759/
  36. Oct 2022
  37. www.sciencedirect.com www.sciencedirect.com
    METTL3 regulates m6A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111530

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    sciencedirect.com/science/article/pii/S2211124722013869
  38. May 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyladenosine Modification
    1
    1. scibot 11 May 2022
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      DOI: 10.3389/fnagi.2022.890134

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    ncbi.nlm.nih.gov/pmc/articles/PMC9084913/
  40. www.sciencedirect.com www.sciencedirect.com
    The Mettl3 epitranscriptomic writer amplifies p53 stress responses
    1
    1. scibot 05 May 2022
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      DOI: 10.1016/j.molcel.2022.04.010

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    sciencedirect.com/science/article/pii/S1097276522003215
  41. Mar 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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    1. scibot 26 Mar 2022
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      DOI: 10.1016/j.molcel.2022.02.033

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    sciencedirect.com/science/article/pii/S1097276522002076
  43. Nov 2021
  44. www.sciencedirect.com www.sciencedirect.com
    HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease
    1
    1. scibot 30 Nov 2021
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      DOI: 10.1016/j.molcel.2021.10.028

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    sciencedirect.com/science/article/pii/S1097276521009485
  45. Jun 2021
  46. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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      ab195352

      DOI: 10.1002/2211-5463.13165

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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13165
  47. May 2021
  48. www.cell.com www.cell.com
    The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth
    1
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      DOI: 10.1016/j.ccell.2021.04.016

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    cell.com/cancer-cell/fulltext/S1535-6108(21)00224-5
  49. www.sciencedirect.com www.sciencedirect.com
    A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting
    1
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      DOI: 10.1016/j.stem.2021.01.007

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    sciencedirect.com/science/article/pii/S1934590921000072
  50. www.sciencedirect.com www.sciencedirect.com
    Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation
    1
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      DOI: 10.1016/j.molcel.2020.10.026

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    sciencedirect.com/science/article/pii/S1097276520307334
  51. Apr 2021
  52. www.sciencedirect.com www.sciencedirect.com
    A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease
    1
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      DOI: 10.1016/j.cmet.2021.03.024

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    sciencedirect.com/science/article/pii/S1550413121001315
  53. Dec 2020
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epitranscriptomic m6A regulation following spinal cord injury
    1
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      DOI: 10.1002/jnr.24763

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24763
  55. Oct 2020
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    m6A RNA methylation impacts fate choices during skin morphogenesis
    1
    1. scibot 13 Oct 2020
      RRID:AB_2721254

      DOI: 10.7554/eLife.56980

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    ncbi.nlm.nih.gov/pmc/articles/PMC7535931/
  57. Sep 2020
  58. www.sciencedirect.com www.sciencedirect.com
    Modulation of circRNA Metabolism by m6A Modification
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    1. scibot 16 Sep 2020
      RRID:AB_2721254

      DOI: 10.1016/j.celrep.2020.107641

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    sciencedirect.com/science/article/pii/S2211124720305945
  59. www.sciencedirect.com www.sciencedirect.com
    METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation
    1
    1. scibot 10 Sep 2020
      RRID:AB_2721254

      DOI: 10.1016/j.molcel.2020.06.017

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    sciencedirect.com/science/article/pii/S1097276520304020
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay
    1
    1. scibot 13 Jan 2020
      RRID:AB_2721254

      DOI: 10.1016/j.molcel.2019.06.001

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    sciencedirect.com/science/article/pii/S1097276519304344
  62. www.sciencedirect.com www.sciencedirect.com
    N6-Methyladenosine Modification Controls Circular RNA Immunity
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.07.016

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      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2721254

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      RRID:AB_2721254 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519305465
  63. Nov 2018
  64. www.sciencedirect.com www.sciencedirect.com
    Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
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    1. scibot 05 Nov 2018
      RRID:AB_2721254

      Curator: @Jmenke

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      (Abcam Cat# ab195352, RRID:AB_2721254)

      SciCrunch record: RRID:AB_2721254

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2721254 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518301345