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Dynamicity of Topoisomerase 1 binding at super-enhancers regulates TLR-responsive gene expression program in macrophages

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1. scibot 29 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117604
  
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sciencedirect.com/science/article/pii/S2211124726006820
May 2026
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A regulatory circuitry driving a noradrenergic to mesenchymal transition highlights YAP/TAZ as critical players in neuroblastoma plasticity

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1. scibot 19 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117351
  
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sciencedirect.com/science/article/pii/S2211124726004298
Apr 2026
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BCOR mutations deregulate cell cycle and hypoxic adaptation pathways in retinoblastoma

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/1541-7786.MCR-24-1078
  
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aacrjournals.org/mcr/article/24/3/179/774760/BCOR-Mutations-Deregulate-Cell-Cycle-and-Hypoxic
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Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-κB signaling in pancreatic cancer

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1. scibot 03 Apr 2026
  
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  DOI: 10.1038/s41420-026-03019-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13039881/
Mar 2026
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A developmentally regulated long-range enhancer-promoter contact mediates human neural development

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1. scibot 18 Mar 2026
  
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  DOI: 10.64898/2025.12.01.691702
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12822576/
Jan 2026
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Role of MNX1-mediated histone modifications and PBX gene family in MNX1-induced leukemogenesis

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1. scibot 23 Jan 2026
  
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  DOI: 10.1038/s41598-026-36367-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12820052/
May 2025
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Generation of Hoxa11-3XFLAG and Hoxd11-3XFLAG alleles to investigate Hox11 genome-wide binding

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.ydbio.2025.05.013
  
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sciencedirect.com/science/article/pii/S0012160625001368
Feb 2025
52.53.155.43 52.53.155.43

1-s2.0-S258900422500238X-main-html.html

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1. scibot 13 Feb 2025
  
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  AB_2722554
  
  DOI: 10.1016/j.isci.2025.111978
  
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52.53.155.43/cf37391079a842c1fd07a8211d5439924f65b0d7/1-s2.0-S258900422500238X-main-html.html
Jan 2025
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CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias

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1. scibot 18 Jan 2025
  
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  DOI: 10.1101/2024.12.30.630680
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11722404/
Dec 2024
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1-s2.0-S2589004224027652-main-html.html

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111538
  
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sciencedirect.com/science/article/pii/S2589004224027652
Aug 2024
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Legionella pneumophila modulates macrophage functions through epigenetic reprogramming via the C-type lectin receptor Mincle

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1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110700
  
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sciencedirect.com/science/article/pii/S2589004224019254
Jul 2024
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Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.immuni.2024.07.001
  
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cell.com/immunity/fulltext/S1074-7613(24)00348-0
Jun 2024
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Transcriptional Synergy in Human Aortic Endothelial Cells is Vulnerable to Combination p300/CBP and BET Bromodomain Inhibition

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1. scibot 14 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11167439/
Mar 2024
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Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma

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1. scibot 03 Mar 2024
  
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  DOI: 10.1158/1541-7786.MCR-22-0916
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10542885/
Nov 2023
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Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development

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1. scibot 18 Nov 2023
  
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  DOI: 10.1016/j.devcel.2023.10.012
  
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sciencedirect.com/science/article/pii/S1534580723005555
Aug 2023
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mcr-22-0916-html.html

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1. scibot 09 Aug 2023
  
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  DOI: 10.1158/1541-7786.mcr-22-0916
  
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52.53.155.43/ee24162242ef05486fd8a6e1481e2011af4e24fe/mcr-22-0916-html.html
Jul 2023
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Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies

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1. scibot 01 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107128
  
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sciencedirect.com/science/article/pii/S2589004223012051
Jan 2023
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A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3

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1. scibot 25 Jan 2023
  
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  DOI: 10.1016/j.isci.2023.105935
  
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sciencedirect.com/science/article/pii/S2589004223000123
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A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia

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1. scibot 07 Jan 2023
  
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  DOI: 10.1038/s41590-022-01370-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9810535/
Dec 2022
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Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111784
  
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sciencedirect.com/science/article/pii/S2211124722016722
Nov 2021
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Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina

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1. scibot 17 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109994
  
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sciencedirect.com/science/article/pii/S221112472101473X
Aug 2021
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Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation

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1. scibot 10 Aug 2021
  
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  DOI: 10.1016/j.ccell.2018.11.017
  
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sciencedirect.com/science/article/pii/S1535610818305385
Sep 2020
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Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution

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1. scibot 06 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.01.049
  
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sciencedirect.com/science/article/pii/S2211124720300747
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Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

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1. scibot 05 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107652
  
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sciencedirect.com/science/article/pii/S2211124720306057
Jan 2020
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Autoregulation of RCO by Low-Affinity Binding Modulates Cytokinin Action and Shapes Leaf Diversity

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cub.2019.10.040
  
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sciencedirect.com/science/article/pii/S0960982219313806
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MicroRNAs Establish the Right-Handed Dominance of the Heart Laterality Pathway in Vertebrates

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.devcel.2019.09.012
  
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sciencedirect.com/science/article/pii/S1534580719307683