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Anti-mitotic agent SB-216 overcomes taxane resistance in castration-resistant prostate cancer and exhibits anti-tumour efficacy in pancreatic cancer

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  DOI: 10.1111/bph.70294
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70294
Nov 2025
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Targeting platelet-tumor cell interactions via thromboxane A2-prostanoid receptor blockade to reduce metastasis in triple negative breast cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12613615/
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Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages

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1. scibot 08 Nov 2025
  
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  DOI: 10.1016/j.stem.2025.10.008
  
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sciencedirect.com/science/article/pii/S1934590925003765
Oct 2025
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Improving immunotherapy responses by dual inhibition of macrophage migration inhibitory factor and PD-1

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1. scibot 30 Oct 2025
  
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  DOI: 10.1172/jci.insight.191539
  
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thompson-et-al-2025-5-hydroxytryptamine-1f-receptor-loss-reduces-renal-vasculature-and-prevents-lasmiditan-induced-html.html

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54.241.53.176/4c40c54fde2c83e2775d1a65a42780e2626d8bbd/thompson-et-al-2025-5-hydroxytryptamine-1f-receptor-loss-reduces-renal-vasculature-and-prevents-lasmiditan-induced-html.html
Sep 2025
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Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C

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1. scibot 27 Sep 2025
  
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  DOI: 10.1371/journal.pbio.3003393
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12463328/
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Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.09.003
  
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sciencedirect.com/science/article/pii/S1074761325004145
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Epigenetic modulation of BARD1 to enhance anti-VEGF therapy

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sciencedirect.com/science/article/pii/S2666379125004021
Aug 2025
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Extracellular vesicle manufacture via FACTORY: fully automated collection technology and optimum machinery for clinical translational applications

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  DOI: 10.1016/j.tibtech.2025.06.020
  
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sciencedirect.com/science/article/pii/S0167779925002598
Jul 2025
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Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer

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1. scibot 04 Jul 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695179/
Jun 2025
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Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice

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1. scibot 15 Jun 2025
  
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  DOI: 10.1101/2025.05.09.653147
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12132566/
May 2025
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Hippo signaling is essential for the maintenance of zona glomerulosa cell fate in the murine adrenal cortex

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1. scibot 21 May 2025
  
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  DOI: 10.1210/endocr/bqaf077
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12041920/
Apr 2025
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1-s2.0-S2589004225006972-main-html.html

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1. scibot 17 Apr 2025
  
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52.53.155.43/be11899c572d4eef940b4fb0c7f6692cd5cc7cb8/1-s2.0-S2589004225006972-main-html.html
Feb 2025
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EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models

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cell.com/cancer-cell/abstract/S1535-6108(25)00031-5
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RSAD2: A pathogenic interferon-stimulated gene at the maternal-fetal interface of patients with systemic lupus erythematosus

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1. scibot 21 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101974
  
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sciencedirect.com/science/article/pii/S2666379125000473
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Bioengineering of a human iPSC-derived vascularized endocrine pancreas for type 1 diabetes

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1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101938
  
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sciencedirect.com/science/article/pii/S2666379125000114
Jan 2025
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Microvascular endothelial cells display organ-specific responses to extracellular matrix stiffness

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.crphys.2025.100140
  
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sciencedirect.com/science/article/pii/S2665944125000021
Nov 2024
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Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma

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1. scibot 21 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.012
  
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sciencedirect.com/science/article/pii/S1535610824004008
Sep 2024
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Granulocyte colony stimulating factor promotes scarless tissue regeneration

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1. scibot 26 Sep 2024
  
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sciencedirect.com/science/article/pii/S2211124724010933
Apr 2024
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The complete Kaposi sarcoma-associated herpesvirus genome induces early-onset, metastatic angiosarcoma in transgenic mice

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cell.com/cell-host-microbe/fulltext/S1931-3128(24)00112-4
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Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis

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  DOI: 10.1158/0008-5472.CAN-23-1542
  
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aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
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Vegfc-expressing cells form heterotopic bone after musculoskeletal injury

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sciencedirect.com/science/article/pii/S2211124724003772
Mar 2024
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Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer

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ncbi.nlm.nih.gov/pmc/articles/PMC10897543/
Nov 2023
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Targeted Nanofitin-drug Conjugates Achieve Efficient Tumor Delivery and Therapeutic Effect in an EGFRpos Mouse Xenograft Model

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ncbi.nlm.nih.gov/pmc/articles/PMC10618730/
Sep 2023
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In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy

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1. scibot 27 Sep 2023
  
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  DOI: 10.1038/s41419-023-06159-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10516902/
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SMAD4 and KCNQ3 alterations are associated with lymph node metastases in Oesophageal adenocarcinoma

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  DOI: 10.1016/j.bbadis.2023.166867
  
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sciencedirect.com/science/article/pii/S0925443923002338
Jul 2023
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FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy

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  DOI: 10.1016/j.celrep.2023.112791
  
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Near-Infrared Photoimmunotherapy Targeting Podoplanin-Expressing Cancer Cells and Cancer-Associated Fibroblasts

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  DOI: 10.1158/1535-7163.MCT-22-0313
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9812859/
Jun 2023
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Macrophage-derived cathepsin S remodels the extracellular matrix to promote liver fibrogenesis

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  DOI: 10.1053/j.gastro.2023.05.039
  
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52.53.155.43/6547da8aa0b8d7e491fdd14880a12803f28db0ef/1-s2.0-S0016508523008120-main-html.html
May 2023
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Establishment of highly metastatic ovarian cancer model with omental tropism via in vivo selection

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.isci.2023.106719
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10183668/
Mar 2023
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Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination

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  DOI: 10.1016/j.celrep.2023.112296
  
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sciencedirect.com/science/article/pii/S2211124723003078
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A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.crmeth.2023.100431
  
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sciencedirect.com/science/article/pii/S2667237523000462
Jan 2023
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Anlotinib Suppressed Ovarian Cancer Progression via Inducing G2/M Phase Arrest and Apoptosis

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1. scibot 11 Jan 2023
  
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  DOI: 10.3390/jcm12010162
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9821756/
Dec 2022
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mct-22-0313-html.html

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1. scibot 30 Dec 2022
  
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  DOI: 10.1158/1535-7163.mct-22-0313
  
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  DOI: 10.1158/1535-7163.MCT-22-0313
  
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Sep 2022
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Inhibition of HIPK2 protects stress-induced pathological cardiac remodeling

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  AB_2722705
  
  DOI: 10.1016/j.ebiom.2022.104274
  
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Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection

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1. scibot 22 Sep 2022
  
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  RRID:AB_2722705
  
  DOI: 10.1128/iai.00070-22
  
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Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency

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  RRID:AB_2722705
  
  DOI: 10.1038/s42003-022-03942-4
  
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Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells

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1. scibot 29 Apr 2022
  
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  RRID:AB_2722705
  
  DOI: 10.1093/carcin/bgac032
  
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Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection

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  DOI: 10.1016/j.celrep.2022.110714
  
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Mar 2022
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Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection

1
1. scibot 26 Mar 2022
  
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  RRID:AB_2722705
  
  DOI: 10.1128/iai.00070-22
  
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Dec 2021
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AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells

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1. scibot 21 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103570
  
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NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis

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  DOI: 10.1016/j.cmet.2021.11.011
  
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mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion

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  DOI: 10.7554/eLife.69015
  
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Sep 2021
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Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion

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  RRID:AB_2722705
  
  DOI: 10.1016/j.ccell.2021.08.008
  
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Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling

1
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  RRID: AB_2722705
  
  DOI: 10.1016/j.ebiom.2019.07.058
  
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Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling

1
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  DOI: 10.1016/j.ccell.2018.11.016
  
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Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

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  DOI: 10.1016/j.molcel.2021.06.014
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)00493-7
May 2021
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Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human

1
1. scibot 20 May 2021
  
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  DOI: 10.1113/JP280922
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP280922
Feb 2021
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Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress

1
1. scibot 26 Feb 2021
  
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  anti-CD31
  
  DOI: 10.1038/s42255-020-00325-z
  
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Dec 2020
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Effects of Cardiomyocyte-Specific Deletion of STAT3–A Murine Model of Heart Failure With Preserved Ejection Fraction

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1. scibot 19 Dec 2020
  
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  DOI: 10.3389/fcvm.2020.613123
  
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Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids

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  DOI: 10.1016/j.cels.2020.11.002
  
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Sep 2020
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A Thermostable mRNA Vaccine against COVID-19

1
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  DOI: 10.1016/j.cell.2020.07.024
  
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Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.ccell.2020.01.011
  
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sciencedirect.com/science/article/pii/S1535610820300507
Nov 2018
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An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2722705
  
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LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling

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1. scibot 05 Nov 2018
  
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  77699S
  
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