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Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer

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1. scibot 03 Dec 2025
  
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  DOI: 10.1158/1078-0432.CCR-25-2201
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12667737/
Nov 2025
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Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer

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1. scibot 24 Nov 2025
  
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  DOI: 10.1038/s41598-025-23137-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12603150/
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Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116526
  
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sciencedirect.com/science/article/pii/S2211124725012975
Oct 2025
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Multi-modal image analysis for large-scale cancer tissue studies within IMMUcan

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1. scibot 23 Oct 2025
  
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  DOI: 10.1016/j.crmeth.2025.101170
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12539258/
Aug 2025
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Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade

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1. scibot 06 Aug 2025
  
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  DOI: 10.1158/2159-8290.CD-24-1390
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319410/
Jun 2025
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Bile acids activate cancer-associated fibroblasts and induce an immunosuppressive microenvironment in cholangiocarcinoma

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.ccell.2025.05.017
  
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sciencedirect.com/science/article/pii/S1535610825002260
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Statistical modeling and analysis of cell counts from multiplexed imaging data

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.cels.2025.101296
  
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cell.com/cell-systems/abstract/S2405-4712(25)00129-2
May 2025
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Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.cmet.2025.04.008
  
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sciencedirect.com/science/article/pii/S1550413125002189
Dec 2024
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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis

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1. scibot 27 Dec 2024
  
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  DOI: 10.1002/ctm2.70149
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11666332/
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Multi-modal analysis reveals tumor and immune features distinguishing EBV-positive and EBV-negative post-transplant lymphoproliferative disorders

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101851
  
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sciencedirect.com/science/article/pii/S2666379124006220
Nov 2024
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Langerhans cells directly interact with resident T cells in the human epidermis

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.xjidi.2024.100324
  
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sciencedirect.com/science/article/pii/S2667026724000729
Jul 2024
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Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.013
  
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sciencedirect.com/science/article/pii/S0092867424006536
May 2024
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Decision model for durable clinical benefit from front- or late-line immunotherapy alone or with chemotherapy in non-small cell lung cancer

1
1. scibot 23 May 2024
  
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  Cell Signaling TechnologyCat#D4W2J, 86163S
  
  DOI: 10.1016/j.medj.2024.04.011
  
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sciencedirect.com/science/article/pii/S2666634024002046
Apr 2024
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Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

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1. scibot 02 Apr 2024
  
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  DOI: 10.1016/j.cell.2024.03.011
  
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sciencedirect.com/science/article/pii/S0092867424003039
Feb 2024
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UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity

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1. scibot 28 Feb 2024
  
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  DOI: 10.1016/j.molcel.2024.01.024
  
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2. scibot 21 Feb 2024
  
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  DOI: 10.1016/j.molcel.2024.01.024
  
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sciencedirect.com/science/article/pii/S1097276524000911
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling

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1. scibot 25 Jan 2024
  
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  DOI: 10.1126/sciadv.adi2012
  
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2. scibot 23 Jan 2024
  
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  DOI: 10.1126/sciadv.adi2012
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
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A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

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1. scibot 05 Jan 2024
  
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  DOI: 10.1016/j.cell.2023.11.037
  
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sciencedirect.com/science/article/pii/S0092867423013223
Nov 2023
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Multi-omics indicators of long-term survival benefits after immune checkpoint inhibitor therapy

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1. scibot 09 Nov 2023
  
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  DOI: 10.1016/j.crmeth.2023.100596
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10626191/
Jun 2023
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Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2

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1. scibot 28 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112693
  
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sciencedirect.com/science/article/pii/S2211124723007040
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Spatially resolved multi-omics single-cell analyses inform mechanisms of immune-dysfunction in pancreatic cancer

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1. scibot 16 Jun 2023
  
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  DOI: 10.1053/j.gastro.2023.05.036
  
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52.53.155.43/71ccfaec92c7763faf07cdf10a5de07b1aba97a1/1-s2.0-S0016508523008107-main-html.html
May 2023
www.nature.com www.nature.com

ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

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1. scibot 20 May 2023
  
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  DOI: 10.1038/s41467-023-38605-3
  
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nature.com/articles/s41467-023-38605-3
Nov 2022
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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

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1. scibot 24 Nov 2022
  
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  DOI: 10.1016/j.ccell.2022.11.002
  
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cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
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Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

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1. scibot 18 Nov 2022
  
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  DOI: 10.1016/j.ccell.2022.10.021
  
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sciencedirect.com/science/article/pii/S1535610822005128
Oct 2021
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Multiplexed imaging reveals an IFN-γ-driven inflammatory state in nivolumab-associated gastritis

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1. scibot 20 Oct 2021
  
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  DOI: 10.1016/j.xcrm.2021.100419
  
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sciencedirect.com/science/article/pii/S2666379121002810
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

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1. scibot 01 Jul 2021
  
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  DOI: 10.1016/j.immuni.2021.06.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8188302/
Feb 2021
www.cell.com www.cell.com

Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

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1. scibot 27 Feb 2021
  
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  RRID:AB_2728833
  
  DOI: 10.1016/j.ccell.2020.08.001
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
Jan 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

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1. scibot 13 Jan 2020
  
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  RRID:AB_2728833
  
  DOI: 10.1016/j.celrep.2019.05.041
  
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pubmed.ncbi.nlm.nih.gov/31189114/
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Untitled document

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.03.005
  
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sciencedirect.com/science/article/pii/S0092867419302673