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Jul 2026
aacrjournals.org aacrjournals.org

IDH1 Reprograms Nucleotide Metabolism by Inducing Chromatin Remodeling and DHODH Transcription to Drive Chemoresistance in Nasopharyngeal Carcinoma

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-2313
  
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aacrjournals.org/cancerres/article/86/8/2004/782636/IDH1-Reprograms-Nucleotide-Metabolism-by-Inducing
May 2026
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Hypoxia-driven lncRNA SHIELD promotes GPX4 translation and protects against ferroptosis in hepatocellular carcinoma

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1. scibot 28 May 2026
  
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  DOI: 10.1016/j.molcel.2026.04.026
  
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sciencedirect.com/science/article/pii/S1097276526002807
Apr 2026
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Tolerance to extracellular acidic pH facilitates tumor plasticity

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117226
  
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sciencedirect.com/science/article/pii/S2211124726003049
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Species-specific cleavage of the autophagy adaptor p62 dictates responses to TNF

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1. scibot 09 Apr 2026
  
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  DOI: 10.1016/j.molcel.2026.03.013
  
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sciencedirect.com/science/article/pii/S1097276526001899
www.nature.com www.nature.com

ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbances

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1. scibot 02 Apr 2026
  
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  DOI: 10.1038/s41420-026-03027-9
  
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nature.com/articles/s41420-026-03027-9
Mar 2026
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Autoinhibitory control of MLKL governs pseudokinase domain phosphorylation and oligomerization during necroptosis

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117130
  
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sciencedirect.com/science/article/pii/S2211124726002081
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bioorthogonal catalytic centres engineered for gastrointestinal stabilization provide oral delivery for the treatment of gastric cancer

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1. scibot 18 Mar 2026
  
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  DOI: 10.1186/s12951-026-04065-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12980911/
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Macrophage metabolic exhaustion and PANoptotic cell death drive chronic tissue inflammation in rheumatoid arthritis

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1. scibot 10 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.01.019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13020464/
Feb 2026
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Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116942
  
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sciencedirect.com/science/article/pii/S2211124726000203
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity

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1. scibot 18 Jun 2025
  
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  DOI: 10.1124/molpharm.124.000894
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12164689/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CCDC134 controls TLR biogenesis through the ER chaperone Gp96

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1. scibot 13 Dec 2024
  
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  DOI: 10.1084/jem.20240825
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11629888/
Sep 2024
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Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101732
  
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sciencedirect.com/science/article/pii/S2666379124004622
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells

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1. scibot 03 Feb 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-1632
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
Aug 2023
www.biorxiv.org www.biorxiv.org

Acylation of MLKL impacts its function in necroptosis

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1. scibot 28 Aug 2023
  
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  RRID:AB_2732034
  
  DOI: 10.1101/2023.08.19.553906
  
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biorxiv.org/content/10.1101/2023.08.19.553906v1
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma

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1. scibot 20 Jan 2023
  
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  DOI: 10.1158/0008-5472.CAN-21-3217
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

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1. scibot 02 Aug 2022
  
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  DOI: 10.1016/j.cell.2022.06.038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9531054/
Jan 2022
link.springer.com link.springer.com

Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells

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1. scibot 05 Jan 2022
  
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  91689
  
  DOI: 10.1007/978-1-0716-2071-7_10
  
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  RRID:AB_2732034 RRIDCUR:Missing
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link.springer.com/protocol/10.1007/978-1-0716-2071-7_10
Nov 2021
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Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation

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1. scibot 09 Nov 2021
  
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  RRID:AB_2732034
  
  DOI: 10.1016/j.isci.2021.103256
  
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sciencedirect.com/science/article/pii/S2589004221012256
Oct 2021
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Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity

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1. scibot 30 Oct 2021
  
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  DOI: 10.1016/j.immuni.2021.10.007
  
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sciencedirect.com/science/article/pii/S1074761321004441
May 2021
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RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis

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1. scibot 12 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109112
  
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sciencedirect.com/science/article/pii/S2211124721004460
Apr 2021
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Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis

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1. scibot 13 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2021.03.012
  
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  RRIDCUR:Validated RRID:AB_2732034
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sciencedirect.com/science/article/pii/S2451945621001513
Sep 2020
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Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

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1. scibot 12 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107652
  
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sciencedirect.com/science/article/pii/S2211124720306057