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    Opposing excitatory and inhibitory synaptic pathologies drive ZC4H2-associated intellectual disability
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    sciencedirect.com/science/article/pii/S0896627326007786
  3. Oct 2026
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    Hippocampal ring finger protein 10-dependent signaling supports cognitive flexibility
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    sciencedirect.com/science/article/pii/S2589004226030324
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    Activation of TREM2 via single-domain antibodies improves synaptic and cognitive function in 5×FAD mice
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    sciencedirect.com/science/article/pii/S2211124726011423
  6. Apr 2026
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  8. Sep 2025
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    β2AR as a target in methamphetamine addiction: Divergent mechanisms from TAAR1
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    Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12426952/
  11. Aug 2025
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    Conditional deletion of TRPC1 channel modulates synaptic plasticity, long term depression, and memory extinction in Fragile X Syndrome mice.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12329558/
  13. Jul 2025
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  15. Jun 2025
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    TNFR2 contributes to synaptic potentiation failure in hippocampal synapses and memory loss in a familial Alzheimer’s disease mouse model
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    CXCL12 engages cortical inhibitory neurons to enhance dendritic spine plasticity and structured network activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12160403/
  18. May 2025
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    Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain
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  20. Oct 2024
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    GPR158 in pyramidal neurons mediates social novelty behavior via modulating synaptic transmission in male mice
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    sciencedirect.com/science/article/pii/S2211124724011471
  22. Aug 2024
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    Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11333793/
  24. Jul 2024
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    A cingulate-hippocampal circuit mediates early depressive-like behavior in the mouse model of Alzheimer’s disease
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  26. Apr 2024
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    Overexpression of α-Klotho isoforms promotes distinct Effects on BDNF-Induced Alterations in Dendritic Morphology
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  28. Mar 2024
  29. elifesciences.org elifesciences.org
    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
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    elifesciences.org/articles/89453
  30. Feb 2024
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    Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint
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    onlinelibrary.wiley.com/doi/10.1111/ejn.16279
  32. Aug 2023
  33. 52.53.155.43 52.53.155.43
    Stress-mediated dysregulation of the Rap1 small GTPase impairs hippocampal structure and function
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    S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus
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  35. Apr 2023
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    A cingulate-hippocampal circuit mediates early depressive symptoms in Alzheimer’s disease
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  37. Mar 2023
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    Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats
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    mdpi.com/2218-273X/13/3/516
  39. Feb 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
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    Translational patterns of ionotropic glutamate and GABA receptors during brain development and behavioral stimuli revealed by polysome profiling
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    onlinelibrary.wiley.com/doi/epdf/10.1111/jnc.15771
  42. Dec 2022
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    Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning
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    sciencedirect.com/science/article/pii/S2211124722016497
  44. Apr 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9021533/
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    Taurine Alleviates Chronic Social Defeat Stress-Induced Depression by Protecting Cortical Neurons from Dendritic Spine Loss
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    link.springer.com/article/10.1007/s10571-022-01218-3
  47. Mar 2022
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    Activity-dependent PI4P synthesis by PI4KIIIα regulates long-term synaptic potentiation
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    sciencedirect.com/science/article/pii/S2211124722001796
  49. Oct 2021
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    Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
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  51. Aug 2021
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    NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
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    sciencedirect.com/science/article/pii/S2211124721009451
  53. www.jneurosci.org www.jneurosci.org
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    jneurosci.org/content/38/45/9700
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood
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    ncbi.nlm.nih.gov/pmc/articles/PMC6222060/
  55. Jul 2021
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    Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
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    sciencedirect.com/science/article/pii/S2405844021015590
  57. May 2021
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    Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
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    sciencedirect.com/science/article/pii/S2589004221004727
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Neuroprotective Beta Amyloid Hexapeptide Core Reverses Deficits in Synaptic Plasticity in the 5xFAD APP/PS1 Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC8075567/
  60. Feb 2021
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    Maternal high fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring
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    academic.oup.com/endo/article/162/1/bqaa214/5992137
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    Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC7609054/
  63. Dec 2020
  64. www.mdpi.com www.mdpi.com
    Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats
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    mdpi.com/2072-6643/12/12/3661
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    Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer’s Disease
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  66. Sep 2020
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    Quantitative immunoblotting analyses reveal that the abundance of actin, tubulin, synaptophysin and EEA1 proteins is altered in the brains of aged mice
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    sciencedirect.com/science/article/pii/S0306452220304255
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15211
  69. Jan 2020
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    The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling
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    sciencedirect.com/science/article/pii/S2211124719311532
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    The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling
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    eneuro.org/content/6/1/ENEURO.0242-18.2019