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The chromatin context differently impacts prime editors and base editors and controls the fidelity and purity of base editing

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1. scibot 06 Nov 2026
  
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  DOI: 10.1016/j.molcel.2026.10.012
  
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sciencedirect.com/science/article/pii/S1097276526007173
Oct 2026
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mChIP-seq for multiplex epigenomic profiling uncovers cancer-specific histone features in cellular and circulating nucleosomes

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1. scibot 23 Oct 2026
  
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  DOI: 10.1016/j.crmeth.2026.101641
  
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sciencedirect.com/science/article/pii/S2667237526003425
Sep 2026
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Menin orchestrates corticogenesis via regulation of chromatin accessibility and activation of EphA4 in late-born neurons

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1. scibot 03 Sep 2026
  
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  DOI: 10.1016/j.celrep.2026.117916
  
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sciencedirect.com/science/article/pii/S2211124726009940
Jul 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Transcriptional Reprogramming by AP-1-Bound Cis-Regulatory Elements Is Associated with Melanoma Development

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1. scibot 30 Jul 2026
  
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  AB_2732926
  
  DOI: 10.3390/ijms27146459
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13411661/
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting RANKL-independent osteoclastogenesis overcomes denosumab resistance in models of ER+ breast cancer bone metastasis

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1. scibot 06 Jun 2026
  
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  DOI: 10.1172/JCI199285
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13178652/
Apr 2026
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MRE11 proximal polyadenylation site-mediated looping impacts transcription and genomic stability

1
1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.molcel.2026.03.032
  
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sciencedirect.com/science/article/pii/S109727652600208X
Nov 2025
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Nuclear-lamin-guided plastic positioning and folding of the human genome

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1. scibot 08 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116529
  
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sciencedirect.com/science/article/pii/S2211124725013002
Aug 2025
52.53.155.43 52.53.155.43

2025.08.13.670051v1.full-html.html

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1. scibot 19 Aug 2025
  
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  RRID:AB_2732926
  
  DOI: 10.1101/2025.08.13.670051
  
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52.53.155.43/9ae938628208cf1791b8d2e8710fdaf8af2a6149/2025.08.13.670051v1.full-html.html
Jun 2025
elifesciences.org elifesciences.org

Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma

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1. scibot 11 Jun 2025
  
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  i
  
  DOI: 10.7554/eLife.105339.1
  
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elifesciences.org/reviewed-preprints/105339v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

LEADR, a p63 target, dampens interferon signalling in bladder cancer

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1038/s41420-025-02546-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12134291/
Apr 2025
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DUX-mediated configuration of p300/CBP drives minor zygotic genome activation independent of its catalytic activity

1
1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115544
  
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sciencedirect.com/science/article/pii/S2211124725003158
Mar 2025
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Base-pair resolution reveals clustered R-loops and DNA damage-susceptible R-loops

1
1. scibot 20 Mar 2025
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.molcel.2025.02.019
  
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sciencedirect.com/science/article/pii/S1097276525001509
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Resolving the three-dimensional interactome of human accelerated regions during human and chimpanzee neurodevelopment

1
1. scibot 31 Jan 2025
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.cell.2025.01.007
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11928272/
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Deciphering transcription activity of mammalian early embryos unveils on/off of zygotic genome activation by protein translation/degradation

1
1. scibot 17 Jan 2025
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.celrep.2024.115215
  
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sciencedirect.com/science/article/pii/S2211124724015663
Dec 2024
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Frizzled5 controls murine intestinal epithelial cell plasticity through organization of chromatin accessibility

1
1. scibot 06 Dec 2024
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.devcel.2024.10.021
  
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sciencedirect.com/science/article/pii/S1534580724006610
Nov 2024
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ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss

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1. scibot 17 Nov 2024
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.molcel.2024.10.020
  
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sciencedirect.com/science/article/pii/S1097276524008608
Sep 2024
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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

1
1. scibot 10 Sep 2024
  
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  AB_2732926
  
  DOI: 10.1016/j.cell.2024.08.014
  
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sciencedirect.com/science/article/pii/S009286742400905X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

1
1. scibot 04 Sep 2024
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.ccell.2024.08.006
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11865364/
Jul 2024
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Cell-type-specific loops linked to RNA polymerase II elongation in human neural differentiation

1
1. scibot 11 Jul 2024
  
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  DOI: 10.1016/j.xgen.2024.100606
  
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sciencedirect.com/science/article/pii/S2666979X24002003
Feb 2024
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Maternal KLF17 controls zygotic genome activation by acting as a messenger for RNA Pol II recruitment in mouse embryos

1
1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.devcel.2024.01.013
  
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sciencedirect.com/science/article/pii/S1534580724000327
Sep 2023
52.53.155.43 52.53.155.43

British J Pharmacology - 2023 - Su-html.html

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1. scibot 22 Sep 2023
  
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  RRID:AB_2732926
  
  DOI: 10.1111/bph.16240
  
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52.53.155.43/78b3cb40c26a3e87d0e680de40f4d0777a8366ee/British J Pharmacology - 2023 - Su-html.html
May 2023
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Disruption of CDK7 signaling leads to catastrophic chromosomal instability coupled with a loss of condensin-mediated chromatin compaction

1
1. scibot 18 May 2023
  
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  AB_2732926
  
  DOI: 10.1016/j.jbc.2023.104834
  
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sciencedirect.com/science/article/pii/S0021925823018628
Apr 2023
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Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting

1
1. scibot 06 Apr 2023
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.molcel.2023.02.007
  
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sciencedirect.com/science/article/pii/S1097276523001028
Mar 2023
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The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11

1
1. scibot 11 Mar 2023
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.celrep.2023.112234
  
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sciencedirect.com/science/article/pii/S2211124723002450
Jan 2023
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Multi-omics profiling visualizes dynamics of cardiac development and functions

1
1. scibot 28 Jan 2023
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.celrep.2022.111891
  
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sciencedirect.com/science/article/pii/S2211124722017909
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency

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1. scibot 02 Feb 2022
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.isci.2021.103525
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8786646/
Jan 2022
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Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response

1
1. scibot 26 Jan 2022
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.molcel.2021.12.035
  
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sciencedirect.com/science/article/pii/S1097276521011400
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Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2

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1. scibot 26 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110253
  
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sciencedirect.com/science/article/pii/S2211124721017654
Dec 2021
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MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

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1. scibot 15 Dec 2021
  
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  DOI: 10.1016/j.molcel.2021.11.015
  
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sciencedirect.com/science/article/pii/S1097276521009953
Jul 2021
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Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

1
1. scibot 29 Jul 2021
  
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  RRID: 2732926
  
  DOI: 10.1016/j.celrep.2019.10.083
  
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sciencedirect.com/science/article/pii/S2211124719314056
May 2021
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Loss of interleukin-10 receptor disrupts intestinal epithelial cell proliferation and skews differentiation towards the goblet cell fate

1
1. scibot 29 May 2021
  
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  39097
  
  DOI: 10.1096/fj.202002369R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002369R
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Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.07.015
  
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sciencedirect.com/science/article/pii/S1934590920303532
Apr 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer

1
1. scibot 17 Apr 2021
  
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  AB_2732926
  
  DOI: 10.1016/j.ccell.2020.04.016
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7363581/
Feb 2021
www.cell.com www.cell.com

Motif orientation matters: structural characterization of TEAD1 recognition of genomic DNA

1
1. scibot 26 Feb 2021
  
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  DOI: 10.1016/j.str.2020.11.018
  
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cell.com/structure/abstract/S0969-2126(20)30465-2
Sep 2020
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A Prion Epigenetic Switch Establishes an Active Chromatin State

1
1. scibot 13 Sep 2020
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.cell.2020.02.014
  
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DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex

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1. scibot 10 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.03.024
  
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KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs

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1. scibot 06 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.04.024
  
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Jan 2020
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Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.12.011
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.ccell.2018.12.009
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2732926
  
  DOI: 10.1016/j.molcel.2018.11.036
  
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  Curator: @evieth
  
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