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Mechanical stress attenuates the metabolic reprogramming and M1 polarization of macrophages by upregulating integrin subunit alpha D

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  DOI: 10.1016/j.cellsig.2026.112666
  
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sciencedirect.com/science/article/pii/S0898656826003219
Feb 2026
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Protocol for modeling innate immune training by repeated alum exposure in mice (adjuvant conditioning)

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Tfam-mediated metabolic perturbation in RORγt+ lymphocytes impacts intestinal tissue homeostasis and promotes GATA3+RORγt+ innate lymphoid cells

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1. scibot 12 Feb 2026
  
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sciencedirect.com/science/article/pii/S2211124726000306
Jan 2026
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CCL5 deficiency aggravates acute DSS-induced colitis by restricting IL-33-induced formation of Tregs in intestinal tract

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1. scibot 09 Jan 2026
  
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  DOI: 10.1042/CS20256734
  
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Adventitial fibroblast-derived NAMPT is associated with vascular remodeling in erythropoietin-induced abdominal aortic aneurysm

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Deletion of the Mouse Homolog of Human FHR1 (muFHR1) Alleviates Atherosclerosis in ApoE-/- mice

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1. scibot 06 Jan 2026
  
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  DOI: 10.7150/ijms.114990
  
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medsci.org/v23p0585.htm
Nov 2025
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The transcription factor NFIL3 drives innate lymphoid cell specification from lymphoid progenitors

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Oct 2025
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CCL26 and CXCL12 preserve insulin-sensitizing macrophages in subcutaneous adipose tissue in obesity

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Aug 2025
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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

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1. scibot 30 Aug 2025
  
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Type I interferon signaling promotes kainic acid-induced seizures through mTOR activation

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  DOI: 10.1016/j.neuropharm.2025.110634
  
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Jul 2025
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Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/0008-5472.CAN-23-3252
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12214878/
May 2025
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IL-33/ST2 signaling in ILC2s drives exhaustion and myeloid skewing of HSCs in response to hematopoietic stress and aging

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1. scibot 18 May 2025
  
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The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115656
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00427-9
Feb 2025
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Blockade of TSP-1/CD47 signal axis promotes donor hematopoietic engraftment by improving SEC/MK niche function

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1. scibot 21 Feb 2025
  
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Nov 2024
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Stepwise Ultra-pH-Sensitive Micelles Overcome a pKa Barrier for Systemic Lymph Node Delivery

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1. scibot 29 Nov 2024
  
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  DOI: 10.1021/acsnano.4c00876
  
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Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection

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1. scibot 15 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114951
  
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Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.cell.2024.10.028
  
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Local adaptive immunity in atherosclerosis with T cell activation by aortic DCs accelerates pathogenesis

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1. scibot 08 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111144
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11536043/
Aug 2024
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Stepwise Ultra-pH-Sensitive Micelles Overcome a pKa Barrier for Systemic Lymph Node Delivery

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1. scibot 02 Aug 2024
  
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Jul 2024
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The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation

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1. scibot 18 Jul 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11250905/
Apr 2024
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The ecotin-like peptidase inhibitor of Trypanosoma cruzi prevents TMPRSS2-PAR2-TLR4 crosstalk downmodulating infection and inflammation

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  DOI: 10.1096/fj.202302091RR
  
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Expression of a mutant CD47 protects against phagocytosis without inducing cell death or inhibiting angiogenesis

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ncbi.nlm.nih.gov/pmc/articles/PMC10983038/
Mar 2024
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A tetravalent nanovaccine that inhibits growth of HPV-associated head and neck carcinoma via dendritic and T cell activation

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Epithelial-derived interleukin-23 promotes oral mucosal immunopathology

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  DOI: 10.1016/j.immuni.2024.02.020
  
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Deficiency of lncRNA MERRICAL abrogates macrophage chemotaxis and diabetes-associated atherosclerosis

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Nov 2023
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Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

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  DOI: 10.1016/j.ccell.2023.11.001
  
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Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis

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  DOI: 10.1016/j.xcrm.2023.101278
  
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Oct 2023
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Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury

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  DOI: 10.1016/j.isci.2023.107947
  
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Sep 2023
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Endothelial-derived small extracellular vesicles support B-cell acute lymphoblastic leukemia development

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  DOI: 10.1007/s13402-023-00855-0
  
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link.springer.com/article/10.1007/s13402-023-00855-0
Aug 2023
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Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models

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Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis

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May 2023
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VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection

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  DOI: 10.1016/j.celrep.2023.112489
  
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Mar 2023
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Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ

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1. scibot 30 Mar 2023
  
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  DOI: 10.3390/cancers15061866
  
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mdpi.com/2072-6694/15/6/1866
Feb 2023
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Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

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  DOI: 10.1016/j.cell.2022.12.038
  
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Jan 2023
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Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells

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Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota

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Metronomic cyclophosphamide is more effective than a single dose in resistant tumours Cyclophosphamide depletes tumour infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma

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CXCR4high megakaryocytes regulate host-defense immunity against bacterial pathogens

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D-tryptophan suppresses enteric pathogens and pathobionts and prevents colitis by modulating microbial tryptophan metabolism

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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging

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Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model

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The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade

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Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection

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Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor

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Club cells form lung adenocarcinomas and maintain the alveoli of adult mice

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Jun 2021
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Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression

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Mar 2021
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In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse

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Feb 2021
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Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

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Jan 2021
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Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen

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Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models

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PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction

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Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia

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Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence

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Lymph Node Stromal Cells Generate Antigen-Specific Regulatory T Cells and Control Autoreactive T and B Cell Responses

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Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

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Untitled document

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Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles

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