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    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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  5. May 2024
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    Hepatokine ITIH3 Protects Against Hepatic Steatosis by Downregulating Mitochondrial Bioenergetics and De Novo Lipogenesis
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  7. Apr 2024
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    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
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    Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon-stimulated gene TRIM21
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis
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  12. Mar 2024
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    Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation
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    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
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  15. Feb 2024
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    Gut-Brain Axis Interplay via STAT3 pathway: Implications of Helicobacter pylori derived secretome on inflammation and Alzheimer's disease
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    Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
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  18. Dec 2023
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    IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects
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    Aedes aegypti saliva modulates inflammasome activation and facilitates flavivirus infection in vitro
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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  22. Nov 2023
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    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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  24. Oct 2023
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    Serotonin reduction in post-acute sequelae of viral infection
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    MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling
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    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
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  28. Jul 2023
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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  30. Jun 2023
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    Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  33. May 2023
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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  35. Apr 2023
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    Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
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  37. Mar 2023
  38. europepmc.org europepmc.org
    Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination
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    europepmc.org/article/med/36952346
  39. Feb 2023
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    SECTM1 is upregulated in immuno-hot tumors and predicts immunotherapeutic efficacy in multiple cancers
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    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
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      DOI: 10.1158/2159-8290.CD-22-0528

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  43. Jan 2023
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    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
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  46. Dec 2022
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    Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer
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  48. Nov 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
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      DOI: 10.7554/eLife.81606

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    ncbi.nlm.nih.gov/pmc/articles/PMC9651953/
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    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
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    sciencedirect.com/science/article/pii/S1097276522010541
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    Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis
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      DOI: 10.1016/j.neuron.2022.10.028

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    sciencedirect.com/science/article/pii/S0896627322009618
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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  53. Oct 2022
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    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
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    sciencedirect.com/science/article/pii/S221112472201422X
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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
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  56. Sep 2022
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    SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA
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  58. Aug 2022
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    The redox cycling of STAT2 maintains innate immune homeostasis
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
  61. Jun 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model
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  63. May 2022
  64. www.sciencedirect.com www.sciencedirect.com
    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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  65. Apr 2022
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Nicotinamide Phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
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  67. Mar 2022
  68. journals.lww.com journals.lww.com
    Ruxolitinib attenuates secondary injury after traumatic spinal cord injury
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  69. Feb 2022
  70. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
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  71. www.sciencedirect.com www.sciencedirect.com
    Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling
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    Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility
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  73. Jan 2022
  74. www.sciencedirect.com www.sciencedirect.com
    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
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  76. Dec 2021
  77. www.nature.com www.nature.com
    Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
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  78. Oct 2021
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    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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  80. Sep 2021
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    In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
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    Activating a collaborative innate-adaptive immune response to control metastasis
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  83. Jul 2021
  84. www.nature.com www.nature.com
    IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners
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  85. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
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  86. www.embopress.org www.embopress.org
    PML-NB-dependent type I interferon memory results in a restricted form of HSV latency
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  87. Jun 2021
  88. www.hindawi.com www.hindawi.com
    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
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  89. www.frontiersin.org www.frontiersin.org
    Promotion of Bone Lesions Through the Myeloma Integrin α6-Mediated Osteolytic Signaling
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      DOI: 10.3389/fonc.2021.692190

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  90. May 2021
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    Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus
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  92. Apr 2021
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    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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  94. Mar 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
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  96. Feb 2021
  97. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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    Evasion of type-I interferon by SARS-CoV-2
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    Disruption of DNA polymerase ζ engages an innate immune response
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  100. Jan 2021
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    MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells
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  102. Oct 2020
  103. www.sciencedirect.com www.sciencedirect.com
    Evasion of type-I interferon by SARS-CoV-2
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  104. Sep 2020
  105. rupress.org rupress.org
    Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
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  106. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  107. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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  108. Jan 2020
  109. www.sciencedirect.com www.sciencedirect.com
    Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
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    Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons
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    STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production
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  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of peroxisome proliferator‐activated receptor delta suppresses BACE1 expression by up‐regulating SOCS1 in a JAK2/STAT1‐dependent manner
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    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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    Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface
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    Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility
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