58 Matching Annotations
  1. Sep 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Berberine, a natural molecular glue degrader, overcomes CML resistance via TRIM28-mediated HIF1α ubiquitination and subsequent ferroptosis
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    sciencedirect.com/science/article/pii/S2211124726009678
  3. www.biorxiv.org www.biorxiv.org
    KLF4 promotes apoptosis evasion and PARP inhibitor resistance in BRCA2-mutated epithelial ovarian cancer
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    biorxiv.org/content/10.64898/2026.08.23.746472v1
  4. Aug 2026
  5. www.sciencedirect.com www.sciencedirect.com
    MAPK-driven MYC/p21 axis controls senescence bypass and BCL-XL dependence in vincristine-resistant rhabdomyosarcoma
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    sciencedirect.com/science/article/pii/S2589004226027021
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    ONC201 enhances the radiosensitivity of small-cell lung cancer via inhibition of the FAK signaling pathway
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    sciencedirect.com/science/article/pii/S2589004226025800
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    Aggregation and propagation of TAF15 trigger neurodegeneration
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    sciencedirect.com/science/article/pii/S0896627326004903
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JI017 Sensitizes EGFR-T790M NSCLC to Erlotinib by Extinguishing the STAT3–Survivin Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13438235/
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    Glycolytic reprogramming and the EMT drive cervical cancer progression via the NQO1/HIF1α-SIX1 axis
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    sciencedirect.com/science/article/pii/S2589004226023850
  10. Jul 2026
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    Tuberostemonine ameliorates Alzheimer’s disease pathology by suppression of the p38 MAPK signaling pathway
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    sciencedirect.com/science/article/pii/S2589004226022650
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    Targeting KIF11 Degradation: Oxypeucedanin Inhibits Lung Adenocarcinoma Progression by Disrupting the MCM2-CDK1 Signaling Pathway
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    sciencedirect.com/science/article/pii/S0944711326008421
  13. Jun 2026
  14. 54.241.53.176 54.241.53.176
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  15. Apr 2026
  16. 54.241.53.176 54.241.53.176
    2026.04.20.719456.full-html.html
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  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HIV gp120 induces TREM1 expression through TLR–PGE₂ signalling in human monocyte-derived microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC13069711/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MiR-1202 increases radioresistance in nasopharyngeal carcinoma by targeting NAIF1/MAPK/ERK pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13053778/
  19. Feb 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unraveling Network Pharmacology‐Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12920268/
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  22. Jan 2026
  23. www.sciencedirect.com www.sciencedirect.com
    Uncovering the signatures of aging and senescence in the human dorsolateral prefrontal cortex
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    sciencedirect.com/science/article/pii/S2666979X25003830
  24. www.aging-us.com www.aging-us.com
    Aging | Sodium cantharidate targets STAT3 and abrogates EGFR inhibitor resistance in osteosarcoma - Full Text
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    aging-us.com/article/102193/text
  25. Sep 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ALKBH1 drives tumorigenesis and drug resistance via tRNA decoding reprogramming and codon-biased translation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12377461/
  27. Aug 2025
  28. www.sciencedirect.com www.sciencedirect.com
    Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis
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    sciencedirect.com/science/article/pii/S153458072500471X
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Valproic acid improves the efficacy of oxaliplatin/fluoropyrimidine-based chemotherapy by targeting cancer stem cell via β-Catenin modulation in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316941/
  30. Jun 2025
  31. www.cell.com www.cell.com
    BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways
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    cell.com/cell-reports/fulltext/S2211-1247(25)00550-9
  32. May 2025
  33. www.sciencedirect.com www.sciencedirect.com
    Stromal lipid species dictate melanoma metastasis and tropism
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    sciencedirect.com/science/article/pii/S1535610825001382
  34. Apr 2025
  35. www.sciencedirect.com www.sciencedirect.com
    Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance
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    sciencedirect.com/science/article/pii/S1535610825001321
  36. Feb 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Meprin β regulates osteopontin-signaling in ischemia/reperfusion-induced kidney injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC11846229/
  38. Jan 2025
  39. 52.53.155.43 52.53.155.43
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  40. Dec 2024
  41. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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    sciencedirect.com/science/article/pii/S0092867424013242
  42. Aug 2024
  43. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
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    cellandbioscience.biomedcentral.com/article/10.1186/s13578-021-00640-2
  44. Jun 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166694/
  46. www.sciencedirect.com www.sciencedirect.com
    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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    sciencedirect.com/science/article/pii/S2589004224010502
  47. Feb 2024
  48. link.springer.com link.springer.com
    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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    link.springer.com/article/10.1038/s41388-024-02968-8
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BCL2 overcomes resistance and augments response to aurora kinase B inhibition by AZD2811 in small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527398/
  50. 52.53.155.43 52.53.155.43
    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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  51. Jan 2024
  52. 52.53.155.43 52.53.155.43
    LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis
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  53. Nov 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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    sciencedirect.com/science/article/pii/S2666379123004846
  55. www.sciencedirect.com www.sciencedirect.com
    Exosomes derived from platelet-rich plasma promote diabetic wound healing via the JAK2/STAT3 pathway
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    sciencedirect.com/science/article/pii/S2589004223023131
  56. Sep 2023
  57. www.embopress.org www.embopress.org
    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
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    embopress.org/doi/full/10.15252/embr.202356948
  58. Aug 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10393801/
  60. 52.53.155.43 52.53.155.43
    BPS Publications
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    52.53.155.43/d8c850c315bd1ef9a1794152cac296a4123affe5/British J Pharmacology - 2023 - Wang - Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3-html.html
  61. Jul 2023
  62. 52.53.155.43 52.53.155.43
    HIV-1 Tat Upregulates TREM1 Expression in Human Microglia
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    52.53.155.43/628fffd9a87f1df77eec88cccea8cf0c58502533/ji2300152-html.html
  63. Jan 2023
  64. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  65. Sep 2022
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux
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    ncbi.nlm.nih.gov/pmc/articles/PMC9468384/
  67. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Meprin β expression modulates the interleukin-6 mediated JAK2-STAT3 signaling pathway in ischemia/reperfusion-induced kidney injury
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15468
  68. www.sciencedirect.com www.sciencedirect.com
    BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer
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    sciencedirect.com/science/article/pii/S2211124722011287
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9440292/
  70. Jul 2022
  71. www.sciencedirect.com www.sciencedirect.com
    Melatonin attenuates manganese-induced mitochondrial fragmentation by suppressing the Mst1/JNK signaling pathway in primary mouse neurons
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    sciencedirect.com/science/article/pii/S0048969722042310
  72. Mar 2022
  73. www.sciencedirect.com www.sciencedirect.com
    Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma
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    sciencedirect.com/science/article/pii/S2352396422001347
  74. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    elifesciences.org/articles/73150
  75. Feb 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T63 induces apoptosis in nasopharyngeal carcinoma cells through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC8797319/
  77. Nov 2021
  78. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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    sciencedirect.com/science/article/pii/S2211124721014583
  79. Sep 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ observation of mitochondrial biogenesis as the early event of apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8441175/
  81. Aug 2021
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8354203/
  83. www.nature.com www.nature.com
    Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
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    nature.com/articles/s41467-021-24821-2
  84. Jun 2021
  85. cmbl.biomedcentral.com cmbl.biomedcentral.com
    β-elemene alleviates airway stenosis via the ILK/Akt pathway modulated by MIR143HG sponging miR-1275
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    cmbl.biomedcentral.com/articles/10.1186/s11658-021-00261-0
  86. Apr 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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  88. Feb 2021
  89. link.springer.com link.springer.com
    Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells
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    link.springer.com/article/10.1007/s10637-020-01050-w
  90. Sep 2020
  91. www.sciencedirect.com www.sciencedirect.com
    GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningioma
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    sciencedirect.com/science/article/pii/S2352396420303170
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
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    onlinelibrary.wiley.com/doi/10.1002/jcp.29743
  93. Jan 2020
  94. mbio.asm.org mbio.asm.org
    TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function
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    mbio.asm.org/content/10/6/e02638-19