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    Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
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  3. Aug 2024
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    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
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    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00285-7
  6. Jul 2024
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    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
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    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
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    A highly selective inhibitor of discoidin domain receptor-1 (DDR1-IN-1) protects corneal epithelial cells from YAP/ACSL4-mediated ferroptosis in dry eye
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  11. Feb 2024
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    Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses
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    TRPM2 enhances ischemic excitotoxicity by associating with PKCγ
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  14. Jan 2024
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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  16. Nov 2023
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    Triggering endogenous Z-RNA sensing for anti-tumor therapy through ZBP1-dependent necroptosis
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  18. Oct 2023
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    MLKL regulates Cx43 ubiquitinational degradation and mediates neuronal necroptosis in ipsilateral thalamus after focal cortical infarction
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    AMER1 deficiency promotes the distant metastasis of colorectal cancer by inhibiting SLC7A11- and FTL-mediated ferroptosis
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  21. Sep 2023
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    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
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  23. Jun 2023
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    Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis
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  25. May 2023
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    Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response
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  27. Mar 2023
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    S100A8/S100A9 promote progression of multiple myeloma via expansion of megakaryocytes
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  29. Jan 2023
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    SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses
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    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
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  32. Dec 2022
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    DLL3 regulates Notch signaling in small cell lung cancer
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  34. Nov 2022
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    RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation
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  36. Oct 2022
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    CasPlay provides a gRNA-barcoded CRISPR-based display platform for antibody repertoire profiling
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  38. Aug 2022
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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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  40. Jun 2022
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    C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus
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  42. Apr 2022
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    A negative feedback loop of TOR signaling balances growth and stress-response trade-offs in plants
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  44. Mar 2022
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    MiR-205-5p/GGCT attenuates growth and metastasis of papillary thyroid cancer by regulating CD44
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    A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens
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  47. Dec 2021
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    Evolution of a histone variant involved in compartmental regulation of NAD metabolism
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  49. Sep 2021
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    Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species
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  51. Aug 2021
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    CRISPR-based peptide library display and programmable microarray self-assembly for rapid quantitative protein binding assays
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    Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair
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  55. Jul 2021
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    TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma
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      Rabbit anti-His

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    Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8257255/
  58. Jun 2021
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    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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    sciencedirect.com/science/article/pii/S1097276521003622
  60. May 2021
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    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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  62. Apr 2021
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    Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
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      Rabbit monoclonal anti-His

      DOI: 10.1016/j.cmet.2020.11.018

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  64. Jan 2020
  65. www.sciencedirect.com www.sciencedirect.com
    A Phage Protein Aids Bacterial Symbionts in Eukaryote Immune Evasion
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    The Deubiquitinase USP46 Is Essential for Proliferation and Tumor Growth of HPV-Transformed Cancers
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    1. scibot 13 Jan 2020
      RRID:AB_2744546

      DOI: 10.1016/j.chom.2019.02.015

      Resource: (Cell Signaling Technology Cat# 12698, RRID:AB_2744546)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2744546

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      RRID:AB_2744546 RRIDCUR:Validated
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