126 Matching Annotations
  1. Oct 2026
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    Safflower yellow investigates AMPK/mTOR-mediated autophagy to mitigate sevoflurane-induced neuroinflammation and cognitive dysfunction
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    sciencedirect.com/science/article/pii/S1687850726005728
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    MTAP loss upregulates BCAT1 in pancreatic cancer and drives branched-chain amino acid dependency
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    sciencedirect.com/science/article/pii/S2211124726011241
  4. Sep 2026
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    IRX1 suppresses cervical squamous cell carcinoma progression by downregulating ACLY expression to inhibit lipid synthesis
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    sciencedirect.com/science/article/pii/S2589004226024934
  6. Aug 2026
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    Multiomics profiling of plasma reveals lipid-immune dysregulation and exosome remodeling in mpox and mpox-HIV co-infection
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    sciencedirect.com/science/article/pii/S2666634026002679
  8. Jul 2026
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    MZT2A drives epithelial-mesenchymal transition in lung adenocarcinoma via the LGALS3BP/ITGB1/TGF-β/smad2 axis
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    sciencedirect.com/science/article/pii/S2589004226022340
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    Vitamin C attenuates primate bone marrow aging at the molecular and progenitor level
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    sciencedirect.com/science/article/pii/S193459092600233X
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intermittent Fasting Exerts Antidepressant‐Like Effects by Restoring HPA Axis Homeostasis Through Coordinated GR–MR Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13338778/
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    A telomerase-SUCLG2 signaling axis drives drug resistance by protecting persister cells
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    sciencedirect.com/science/article/pii/S2211124726007461
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    Single-cell and machine learning-integrated bulk RNA-seq analysis reveals TKT as an oxidative stress-associated diagnostic biomarker in acute myocardial infarction
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    pmc.ncbi.nlm.nih.gov/articles/PMC13321444/
  14. Jun 2026
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    KDM8 acts as a co-regulator of transcription factor SOX2 for promoting cell pluripotency
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    sciencedirect.com/science/article/pii/S2213671126001748
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    Single-dose dual-indication nanoparticle vaccine co-displaying Pseudomonas aeruginosa antigen and tetanus toxin fragment confers durable protection against mixed exposure
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    sciencedirect.com/science/article/pii/S2590006426005995
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    Mume Flos ameliorates MASLD-associated cognitive impairment by attenuating IL-17/NF-κB-mediated metabolic neuroinflammation
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    link.springer.com/article/10.1007/s11011-026-01883-z
  18. May 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combination Therapy of Sini Decoction and Cyclophosphamide Inhibits Tumor Growth in an Orthotopic Lung Cancer Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC13187382/
  20. Apr 2026
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    Human immune aging clock identifies RUNX1 as a decelerator of T cell senescence
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    sciencedirect.com/science/article/pii/S1074761326000774
  22. Mar 2026
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    The landscape of gene mutations in a cohort of 3353 Han Chinese children with nonsyndromic hearing loss
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    sciencedirect.com/science/article/pii/S2352396426000939
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    aFGF rescues high glucose-induced senescent fibroblasts and improves diabetic wound healing by regulating SIRT1/STAT3 pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12953587/
  25. Feb 2026
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    Functional human salivary gland organoids for tissue regeneration in chemically defined culture systems
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    sciencedirect.com/science/article/pii/S2666379126000297
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    The ANGPTL3-integrin α5 axis drives retinal vascular leakage in diabetic retinopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12896188/
  28. Jan 2026
  29. academic.oup.com academic.oup.com
    Structural insights into the Bre1–Lge1 and RNF20/RNF40–WAC interactions critical for H2B ubiquitination
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    academic.oup.com/nar/article/54/2/gkaf1514/8425315
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    PDCD5 promotes substrate release from the TRiC complex in cilia and flagella
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    sciencedirect.com/science/article/pii/S1097276525009864
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    A CLOCK-targeting lncRNA induces trained immunity against tuberculosis
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  32. Nov 2025
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    EPYC promotes laryngeal cancer carcinogenesis and angiogenesis by docking to VEGFR1: A novel therapeutic target
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    WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair
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  35. Oct 2025
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    Vitamin C conveys geroprotection on primate ovaries
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    Astragalin rescues Cadmium-induced cognitive decline by revering glial metabolic reprogramming and neuroinflammation via the mTOR/HIF-1α axis
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  38. Sep 2025
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    Lmo3-expressing peri-isthmus progenitor cells sustain renewal and repair of the mammalian intestinal telocyte niche
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    Pathogenic phosphorylation of linear ubiquitin machinery causes inflammasome sensor degradation
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    Trefoil factor 2 interacts with A4GNT to regulate inflammation to protect against pneumonia during influenza virus infection
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  42. Aug 2025
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    The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi
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  44. Jun 2025
  45. www.cell.com www.cell.com
    Systematic profiling reveals betaine as an exercise mimetic for geroprotection
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    cell.com/cell/fulltext/S0092-8674(25)00635-X
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    Senescence-resistant human mesenchymal progenitor cells counter aging in primates
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  47. Apr 2025
  48. 52.53.155.43 52.53.155.43
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  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Constructed transferrin receptor-targeted liposome for the delivery of fluvoxamine to improve prognosis in a traumatic brain injury mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12001850/
  50. www.tandfonline.com www.tandfonline.com
    Constructed transferrin receptor-targeted liposome for the delivery of fluvoxamine to improve prognosis in a traumatic brain injury mouse model
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    tandfonline.com/doi/abs/10.1080/10717544.2025.2486840
  51. Feb 2025
  52. www.sciencedirect.com www.sciencedirect.com
    Sweetener aspartame aggravates atherosclerosis through insulin-triggered inflammation
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    Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation
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  54. Jan 2025
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse
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    pmc.ncbi.nlm.nih.gov/articles/PMC11741067/
  56. Dec 2024
  57. www.nature.com www.nature.com
    GEFT inhibits the GSDM-mediated proptosis signalling pathway, promoting the progression and drug resistance of rhabdomyosarcoma
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    nature.com/articles/s41419-024-07243-y
  58. Nov 2024
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    Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells
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    Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging
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  61. Oct 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433901/
  63. Sep 2024
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reduction of TRPV1 expression on neurons due to downregulation of P2X7R in neonatal rat dorsal root ganglion satellite glial cells under co-culture conditions
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    onlinelibrary.wiley.com/doi/10.1111/boc.202400021
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    Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
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  66. Jul 2024
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    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
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    Tumor suppressor KEAP1 promotes HSPA9 degradation, controlling mitochondrial biogenesis in breast cancer
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    The Chemokine CCL2 Promotes Excitatory Synaptic Transmission in Hippocampal Neurons via GluA1 Subunit Trafficking
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    link.springer.com/article/10.1007/s12264-024-01236-9
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    Assembly and activation of EBV latent membrane protein 1
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YZL-51N functions as a selective inhibitor of SIRT7 by NAD+ competition to impede DNA damage repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC11214487/
  72. Jun 2024
  73. www.cell.com www.cell.com
    Oncogenic HPV-induced high expression of ESM1 predicts poor prognosis and regulates aerobic glycolysis in cervical cancer
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    cell.com/iscience/abstract/S2589-0042(24)01337-3
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol to test for the formation of ternary protein complexes in vivo or in vitro using a two-step immunoprecipitation approach
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    ncbi.nlm.nih.gov/pmc/articles/PMC11141244/
  75. May 2024
  76. www.sciencedirect.com www.sciencedirect.com
    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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  77. Apr 2024
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction
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  80. Feb 2024
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    ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation
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    Tumor-derived extracellular vesicle drug delivery system for chemo-photothermal-immune combination cancer treatment
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  83. Jan 2024
  84. www.sciencedirect.com www.sciencedirect.com
    Exercise-induced Musclin determines the fate of fibro-adipogenic progenitors to control muscle homeostasis
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    Acute exposure of microwave impairs attention process by activating microglial inflammation
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  86. Dec 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
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    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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  89. Oct 2023
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    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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  92. Sep 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A heterozygous ZP2 mutation causes zona pellucida defects and female infertility in mouse and human
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  94. Aug 2023
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    Electroacupuncture attenuates myocardial ischemia-reperfusion injury by inhibiting microglial engulfment of dendritic spines
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  96. Jul 2023
  97. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Condensate cooperativity underlies transgenerational gene silencing
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  98. Jun 2023
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    Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/ Cas9 system
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    Serum response factor promotes axon regeneration following spinal cord transection injury
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fasting produces antidepressant-like effects via activating mammalian target of rapamycin complex 1 signaling pathway in ovariectomized mice
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  102. May 2023
  103. www.sciencedirect.com www.sciencedirect.com
    A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response
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    Circulating exosomes from patients with Graves’ disease induce an inflammatory immune response
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  105. Apr 2023
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent hypoxia-induced enhancement of sociability and working memory associates with CNTNAP2 upregulation
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    Protocol to purify the histone deacetylase SIRT6 and assess its activity in vitro
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  108. Mar 2023
  109. europepmc.org europepmc.org
    UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS
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    europepmc.org/article/med/36943869
  110. Jan 2023
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8
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    ncbi.nlm.nih.gov/pmc/articles/PMC9859043/
  112. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    P38γ modulates the lipid metabolism in non-alcoholic fatty liver disease by regulating the JAK–STAT signaling pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202200939RR
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    Resurrection of endogenous retroviruses during aging reinforces senescence
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  114. www.nature.com www.nature.com
    TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal
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  115. Oct 2022
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prenatal exposure to inflammation increases anxiety-like behaviors in F1 and F2 generations: possible links to decreased FABP7 in hippocampus
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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC-mediated silencing of miR-181a-5p promotes pathogenic Th17 responses by modulating AKT3-FOXO3 signaling
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    Long non-coding RNA SNHG5 promotes podocyte injury via the microRNA-26a-5p/TRPC6 pathway in diabetic nephropathy
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    Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR
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    Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation
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  121. journals.lww.com journals.lww.com
    Spliceosomal GTPase Eftud2 regulates microglial activation... : Neural Regeneration Research
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  122. Sep 2022
  123. www.sciencedirect.com www.sciencedirect.com
    Effects of maternal deprivation and environmental enrichment on anxiety-like and depression-like behaviors correlate with oxytocin system and CRH level in the medial-lateral habenula.
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  124. Aug 2022
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