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Ultra-precision deconvolution of spatial transcriptomics decodes immune heterogeneity and fate-defining programs in tissues

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1. scibot 20 May 2026
  
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  DOI: 10.1038/s41467-026-70645-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13168514/
May 2026
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Evaluating T-Cell Clonality In Skin Using a Quantitative TRBC1-Clonality Score

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1. scibot 14 May 2026
  
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  DOI: 10.1016/j.jid.2026.03.045
  
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sciencedirect.com/science/article/pii/S0022202X26012054
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Cancer stem cells orchestrate immune evasion through extracellular vesicle-mediated non-canonical signaling pathways

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.ccell.2026.04.004
  
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sciencedirect.com/science/article/pii/S1535610826002151
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Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

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1. scibot 08 May 2026
  
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  DOI: 10.1002/advs.202509340
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12866796/
Apr 2026
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Vesicle trafficking 1 in breast cancer tissue and serum orchestrates metastatic progression and an immunosuppressive microenvironment

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  DOI: 10.1016/j.intimp.2026.116564
  
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sciencedirect.com/science/article/pii/S1567576926004091
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Unveiling the molecular architecture of T cells and immune synapses with cryo-expansion microscopy

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  DOI: 10.1016/j.celrep.2026.117165
  
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sciencedirect.com/science/article/pii/S2211124726002433
Mar 2026
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Single-cell spatial transcriptomics reveals tumor microenvironment heterogeneity in primary and lymph node-metastatic small cell lung cancer

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102713
  
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sciencedirect.com/science/article/pii/S2666379126001308
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Proteogenomic characterization delineates clinically relevant subtypes of advanced differentiated thyroid cancer

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1. scibot 10 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102661
  
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sciencedirect.com/science/article/pii/S2666379126000789
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Spatial omics study reveals molecular-cellular dynamics of tumor ecosystem in esophageal squamous-cell carcinoma initiation and progression

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1. scibot 06 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102650
  
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sciencedirect.com/science/article/pii/S2666379126000674
Feb 2026
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Resveratrol amplifies the anti-tumor effect of α-PD-1 by altering the intestinal microbiome and PGD2 content

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1. scibot 27 Feb 2026
  
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  DOI: 10.1080/19490976.2024.2447821
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12931716/
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Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102638
  
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sciencedirect.com/science/article/pii/S2666379126000558
Jan 2026
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IGSF11-VISTA is a critical and targetable immune checkpoint axis in diffuse midline glioma

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.020
  
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sciencedirect.com/science/article/pii/S1535610825005549
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B cells disrupt tertiary lymphoid structure formation and suppress anti-tumor immunity

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.011
  
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sciencedirect.com/science/article/pii/S1535610825005458
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Tumor-initiating stem cells fine-tune the plasticity of neutrophils to sculpt a protective niche

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1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.ccell.2025.11.001
  
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sciencedirect.com:5037/science/article/pii/S1535610825004945
Nov 2025
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Mature tertiary lymphoid structures support B cell-mediated antitumour immunity and are disrupted by neoadjuvant therapy in rectal cancer: a multicentre, retrospective study

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.ebiom.2025.106030
  
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sciencedirect.com/science/article/pii/S2352396425004748
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Soluble TIM-3 and galectin-9 predict survival in gastric and gastroesophageal junction cancer

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113871
  
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sciencedirect.com/science/article/pii/S2589004225021327
Sep 2025
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Effects of anlotinib combined with camrelizumab and chemotherapy as first-line treatment for advanced esophageal squamous cell carcinoma on tumor immune microenvironment

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1. scibot 20 Sep 2025
  
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  DOI: 10.21037/jgo-2025-30
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12432929/
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Integrated spatial transcriptomic profiling to dissect the cellular characteristics of tumor-associated tertiary lymphoid structures

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1. scibot 11 Sep 2025
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.celrep.2025.116250
  
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sciencedirect.com/science/article/pii/S2211124725010216
Aug 2025
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inline-supplementary-material-2-html.html

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1. scibot 19 Aug 2025
  
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  DOI: 10.1136/jitc-2025-011818
  
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52.53.155.43/100e14b90da09131bf5c9cf9d4efd569ae25716b/inline-supplementary-material-2-html.html
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Enhanced formation of tertiary lymphoid structures shapes the anti-tumor microenvironment in hepatocellular carcinoma after FOLFOX-HAIC therapy

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102298
  
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sciencedirect.com/science/article/pii/S2666379125003714
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Lymphocyte subset-based non-invasive biomarker predicts immunochemotherapy efficacy in EGFR-TKI-pretreated EGFR-mutated NSCLC

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.isci.2025.113211
  
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sciencedirect.com/science/article/pii/S2589004225014725
Jul 2025
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Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102239
  
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sciencedirect.com/science/article/pii/S266637912500312X
Jun 2025
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An iPSC-derived CD19/BCMA CAR-NK therapy in a patient with systemic sclerosis

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.cell.2025.05.038
  
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cell.com/cell/abstract/S0092-8674(25)00625-7
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Interferon-responsive HEVs drive tumor tertiary lymphoid structure formation and predict immunotherapy response in nasopharyngeal carcinoma

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102200
  
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sciencedirect.com/science/article/pii/S2666379125002733
May 2025
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Tumor immune microenvironment delineates progression trajectories of distinct nasopharyngeal carcinoma phenotypes

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102143
  
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Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.93316
  
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elifesciences.org/articles/93316
Apr 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225007709-main-html.html

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  DOI: 10.1016/j.isci.2025.112509
  
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52.53.155.43/eab743bd464968909a421456d0d09f1e7b027877/1-s2.0-S2589004225007709-main-html.html
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Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

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  DOI: 10.1016/j.cell.2025.03.022
  
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sciencedirect.com/science/article/pii/S0092867425002958
Mar 2025
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Safety and Efficacy of Copanlisib in Combination with Nivolumab: A Phase Ib Study in Patients with Advanced Solid Tumors

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1. scibot 20 Mar 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0407
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11907410/
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Practical microenvironment classification in diffuse large B cell lymphoma using digital pathology

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102030
  
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sciencedirect.com/science/article/pii/S266637912500103X
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T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102027
  
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sciencedirect.com/science/article/pii/S2666379125001004
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CD4+ anti-TGF-β CAR T cells and CD8+ conventional CAR T cells exhibit synergistic antitumor effects

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102020
  
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sciencedirect.com/science/article/pii/S266637912500093X
Feb 2025
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JNJ-78306358, a first-in-class bispecific T cell engaging antibody targeting CD3 and HLA-G

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111876
  
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sciencedirect.com/science/article/pii/S2589004225001361
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Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.ccell.2025.01.009
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00027-3
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Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.stem.2025.01.002
  
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

1
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Neoadjuvant immunotherapy with or without chemotherapy in locally advanced oral squamous cell carcinoma: Randomized, two-arm, phase 2 trial

1
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dgae876-html.html

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Resveratrol amplifies the anti-tumor effect of α-PD-1 by altering the intestinal microbiome and PGD2 content

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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis

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Neoadjuvant chemotherapy by liposomal doxorubicin boosts immune protection of tumor membrane antigens-based nanovaccine

1
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Skin immune-mesenchymal interplay within tertiarylymphoid structures promotes autoimmunepathogenesis in hidradenitis suppurativa

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Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading

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Novel molecular subtypes of METex14 non-small cell lung cancer with distinct biological and clinical significance

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  DOI: 10.1038/s41698-024-00642-6
  
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Benign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain

1
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  DOI: 10.1002/pros.24766
  
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Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors

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Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer

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May 2024
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Decision model for durable clinical benefit from front- or late-line immunotherapy alone or with chemotherapy in non-small cell lung cancer

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Targeting MCL1-driven anti-apoptotic pathways overcomes blast progression after hypomethylating agent failure in chronic myelomonocytic leukemia

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Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence

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Pyroptotic T cell-derived active IL-16 has a driving function in ovarian endometriosis development

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Multicellular ecotypes shape progression of lung adenocarcinoma from ground-glass opacity toward advanced stages

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Mar 2024
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High lymphocyte signature genes expression in parathyroid endocrine cells and its downregulation linked to tumorigenesis

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Mechanisms of HIV-Mediated Blood-Brain Barrier Compromise and Leukocyte Transmigration under the Current Antiretroviral Era.

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Biomarkers of Pathological Complete Response to Neoadjuvant Immunotherapy in Mismatch Repair Deficiency Colorectal Cancer

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Jan 2024
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Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity

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A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

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ccr-23-2213-html.html

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Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors

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Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma

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Granulocyte colony stimulating factor is a novel mediator of T cell suppression and an immunotherapeutic target for women with colon cancer

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  DOI: 10.1158/1078-0432.CCR-22-3918
  
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Oct 2023
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Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma

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Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response

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Sep 2023
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Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity

1
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The local microenvironment drives activation of neutrophils in human brain tumors

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Aug 2023
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Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial

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Jul 2023
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Muscle glycome in Idiopathic Inflammatory Myopathies: impact in IL-6 production and disease prognosis.

1
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  DOI: 10.1016/j.isci.2023.107172
  
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Jun 2023
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Distinct immune microenvironment of lung adenocarcinoma in never-smokers from smokers

1
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  DOI: 10.1016/j.xcrm.2023.101078
  
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May 2023
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CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer

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  DOI: 10.1016/j.medj.2023.04.008
  
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Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer

1
1. scibot 12 May 2023
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.ccell.2023.04.011
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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sciencedirect.com/science/article/pii/S153561082300137X
Apr 2023
aacrjournals.org aacrjournals.org

Addition of losartan to FOLFIRINOX and chemoradiation reduces immunosuppression-associated genes, Tregs and FOXP3+ cancer cells in locally advanced pancreatic cancer

1
1. scibot 21 Apr 2023
  
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  RRID:AB_2750883
  
  DOI: 10.1158/1078-0432.CCR-22-1630
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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aacrjournals.org/clincancerres/article/29/8/1605/725057/Addition-of-Losartan-to-FOLFIRINOX-and
Jan 2023
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Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors

1
1. scibot 19 Jan 2023
  
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  AB_2750883
  
  DOI: 10.1016/j.xcrm.2022.100900
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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sciencedirect.com/science/article/pii/S2666379122004797
Nov 2022
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Impacts of neoadjuvant chemoradiotherapy on the immune landscape of esophageal squamous cell carcinoma

1
1. scibot 24 Nov 2022
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.ebiom.2022.104371
  
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sciencedirect.com/science/article/pii/S2352396422005539
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

High level of intratumoral GITR+ CD4+ T cells associate with poor prognosis in gastric cancer

1
1. scibot 24 Nov 2022
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.isci.2022.105529
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9676631/
Oct 2022
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Interleukin-33-activated neuropeptide CGRP-producing memory Th2 cells cooperate with somatosensory neurons to induce conjunctival itch

1
1. scibot 23 Oct 2022
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.immuni.2022.09.016
  
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sciencedirect.com/science/article/pii/S1074761322005118
Aug 2022
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Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer

1
1. scibot 27 Aug 2022
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.ccell.2022.08.003
  
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sciencedirect.com/science/article/pii/S1535610822003592
May 2022
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Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity

1
1. scibot 12 May 2022
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.ccell.2022.04.004
  
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sciencedirect.com/science/article/pii/S1535610822001660
Apr 2022
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Dorsal clock networks drive temperature preference rhythms in Drosophila

2
1. scibot 15 Apr 2022
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.celrep.2022.110668
  
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2. scibot 15 Apr 2022
  
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  RRID:AB_275088
  
  DOI: 10.1016/j.celrep.2022.110668
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S221112472200420X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas

1
1. scibot 01 Apr 2022
  
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  AB_2750883
  
  DOI: 10.3389/fimmu.2022.824586
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8966496/
Feb 2022
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Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

1
1. scibot 04 Feb 2022
  
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  AB_2750883
  
  DOI: 10.1016/j.ccell.2022.01.003
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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sciencedirect.com/science/article/pii/S1535610822000058
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Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer

1
1. scibot 04 Feb 2022
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.ccell.2022.01.004
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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sciencedirect.com/science/article/pii/S153561082200006X
Oct 2021
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Arthritis flares mediated by tissue-resident memory T cells in the joint

1
1. scibot 27 Oct 2021
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.celrep.2021.109902
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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sciencedirect.com/science/article/pii/S2211124721013723
Aug 2021
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Structured elements drive extensive circular RNA translation

1
1. scibot 26 Aug 2021
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.molcel.2021.07.042
  
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sciencedirect.com/science/article/pii/S1097276521006262
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Localization of enteroviral RNA within the pancreas in donors with T1D and T1D-associated autoantibodies

1
1. scibot 18 Aug 2021
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.xcrm.2021.100371
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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sciencedirect.com/science/article/pii/S2666379121002251
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19

1
1. scibot 28 Mar 2021
  
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  RRID:AB_2750883
  
  DOI: 10.1016/j.immuni.2021.03.005
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7951561/
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

1
1. scibot 26 Feb 2021
  
  in Public
  
  AB_2750883
  
  DOI: 10.1016/j.cell.2020.08.025
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7437499/
Dec 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Cuprizone‐induced demyelination triggers a CD8‐pronounced T cell recruitment

1
1. scibot 07 Dec 2020
  
  in Public
  
  AB_2750883
  
  DOI: 10.1002/glia.23937
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
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onlinelibrary.wiley.com/doi/10.1002/glia.23937
Jan 2020
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Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2750883
  
  DOI: 10.1016/j.cell.2019.10.027
  
  Resource: (Abcam Cat# ab133616, RRID:AB_2750883)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S0092867419311778

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