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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    RNA sensing induced by chromosome missegregation augments anti-tumor immunity
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    1. scibot 21 Dec 2024
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    sciencedirect.com/science/article/pii/S109727652400950X
  3. Dec 2024
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    Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin
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    sciencedirect.com/science/article/pii/S1535610824004483
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    EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
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    sciencedirect.com/science/article/pii/S1535610824004410
  6. Nov 2024
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    ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion
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    1. scibot 24 Nov 2024
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    sciencedirect.com/science/article/pii/S155041312400411X
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    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
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    1. scibot 07 Nov 2024
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      DOI: 10.3389/fonc.2024.1441935

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
  9. Sep 2024
  10. www.sciencedirect.com www.sciencedirect.com
    SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation
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    sciencedirect.com/science/article/pii/S1550413124003322
  11. Jul 2024
  12. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
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    1. scibot 25 Jul 2024
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      DOI: 10.1126/science.adh4567

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    science.org/doi/10.1126/science.adh4567
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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    1. scibot 19 Jul 2024
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    Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer
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    cell.com/cancer-cell/fulltext/S1535-6108(24)00226-5
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    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00362-8
  17. Jun 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Landscape of tumoral ecosystem for enhanced anti-PD-1 immunotherapy by gut Akkermansia muciniphila
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    sciencedirect.com/science/article/pii/S221112472400634X
  19. May 2024
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    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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    1. scibot 08 May 2024
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    sciencedirect.com/science/article/pii/S1550413124001359
  21. Apr 2024
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    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
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    1. scibot 16 Apr 2024
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    sciencedirect.com/science/article/pii/S0092867424003106
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    sciencedirect.com/science/article/pii/S2211124724004169
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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      DOI: 10.1158/1078-0432.CCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    sciencedirect.com/science/article/pii/S0092867424003039
  26. Mar 2024
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    ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951988/
  28. 52.53.155.43 52.53.155.43
    Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.
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  29. Feb 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
    1
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      RRID:AB_275637

      DOI: 10.1158/2767-9764.CRC-23-0399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
  31. Jan 2024
  32. www.nature.com www.nature.com
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    nature.com/articles/s41388-024-02947-z
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    Multi-omics of the gut microbial ecosystem in patients with microsatellite-instability-high gastrointestinal cancer resistant to immunotherapy
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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    sciencedirect.com/science/article/pii/S1534580723003945
  35. Dec 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722136/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
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      DOI: 10.1158/2159-8290.CD-23-0306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10714140/
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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  39. 52.53.155.43 52.53.155.43
    cd-23-0306-html.html
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  40. 52.53.155.43 52.53.155.43
    can-23-1065-html.html
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  41. Nov 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
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      DOI: 10.1158/2767-9764.CRC-23-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
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    FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation
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      DOI: 10.1016/j.celrep.2023.113362

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    sciencedirect.com/science/article/pii/S2211124723013748
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
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    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
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      DOI: 10.1016/j.devcel.2023.10.010

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    sciencedirect.com/science/article/pii/S1534580723005518
  46. Oct 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  48. Aug 2023
  49. www.sciencedirect.com www.sciencedirect.com
    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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      DOI: 10.1016/j.xcrm.2023.101154

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    sciencedirect.com/science/article/pii/S2666379123003075
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
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      DOI: 10.1038/s43856-023-00336-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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      DOI: 10.1016/j.isci.2023.107408

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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
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    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
    1
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      DOI: 10.1016/j.ccell.2021.02.007

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    sciencedirect.com/science/article/pii/S1535610821001094
  53. Jul 2023
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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      DOI: 10.1101/2023.06.27.546707

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  55. Jun 2023
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    Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
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    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
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  61. May 2023
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    Small-molecule MHC-II inducers promote immune detection and anti-cancer immunity via editing cancer metabolism
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
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    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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    Immune landscape of a genetically engineered murine model of glioma compared to human glioma by single-cell sequencing
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    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
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  69. Apr 2023
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    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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  73. Mar 2023
  74. europepmc.org europepmc.org
    Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity
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  75. Jan 2023
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    The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
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    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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  78. Dec 2022
  79. 52.53.155.43 52.53.155.43
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  80. Nov 2022
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    Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy
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  82. Sep 2022
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    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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  85. Aug 2022
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    Fasting renders immunotherapy effective against low-immunogenic breast cancer while reducing side effects
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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  88. Jul 2022
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    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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  90. Jun 2022
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  93. May 2022
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    Topical therapy for regression and melanoma prevention of congenital giant nevi
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  96. Apr 2022
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  98. Mar 2022
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  101. Feb 2022
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    ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression
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  103. Dec 2021
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  105. Sep 2021
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    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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    Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
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  108. Aug 2021
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    Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
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  110. Jun 2021
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    NF1 mutation drives neuronal activity-dependent initiation of optic glioma
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    nature.com/articles/s41586-021-03580-6
  112. May 2021
  113. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [64Cu]Cu-NOTA-anti-CD8-Positron Emission Tomography
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      RRID:AB_2756376

      DOI: 10.1158/1078-0432.CCR-20-3243

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    clincancerres.aacrjournals.org/content/27/7/1958
  114. www.sciencedirect.com www.sciencedirect.com
    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
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      DOI: 10.1016/j.stem.2020.06.022

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    sciencedirect.com/science/article/pii/S1934590920302897
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
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      DOI: 10.1016/j.celrep.2021.109071

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    ncbi.nlm.nih.gov/labs/pmc/articles/PMC8148423/
  116. Apr 2021
  117. www.sciencedirect.com www.sciencedirect.com
    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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      RRID:AB_2756376

      DOI: 10.1016/j.cmet.2020.12.016

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    sciencedirect.com/science/article/pii/S1550413120306719
  118. www.sciencedirect.com www.sciencedirect.com
    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
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      DOI: 10.1016/j.ccell.2021.02.007

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    sciencedirect.com/science/article/pii/S1535610821001094
  119. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  120. Mar 2021
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model
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      DOI: 10.1038/s41598-021-84270-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7933353/
  122. www.sciencedirect.com www.sciencedirect.com
    Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
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      DOI: 10.1016/j.cell.2020.12.031

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    sciencedirect.com/science/article/pii/S0092867420317530
  123. Feb 2021
  124. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Peptides Derived From Insulin Granule Proteins are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice.
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      RRID:AB_2756376

      DOI: 10.2337/db20-0013

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    diabetes.diabetesjournals.org/content/69/12/2678
  125. www.cell.com www.cell.com
    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
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      DOI: 10.1016/j.celrep.2020.01.008

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    cell.com/cell-reports/abstract/S2211-1247(20)30017-6
  126. Jan 2021
  127. www.sciencedirect.com www.sciencedirect.com
    Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing
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      DOI: 10.1016/j.celrep.2020.108566

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    sciencedirect.com/science/article/pii/S2211124720315552
  128. Sep 2020
  129. www.sciencedirect.com www.sciencedirect.com
    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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      DOI: 10.1016/j.ccell.2020.01.011

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    sciencedirect.com/science/article/pii/S1535610820300507
  130. www.cell.com www.cell.com
    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
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      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2020.01.008

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    cell.com/cell-reports/abstract/S2211-1247(20)30017-6
  131. www.sciencedirect.com www.sciencedirect.com
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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      RRID:AB_2756376

      DOI: 10.1016/j.ccell.2019.12.006

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    sciencedirect.com/science/article/pii/S1535610819305768
  132. www.sciencedirect.com www.sciencedirect.com
    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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      RRID:AB_2756376

      DOI: 10.1016/j.stem.2020.02.001

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    sciencedirect.com/science/article/pii/S1934590920300540
  133. Jan 2020
  134. www.sciencedirect.com www.sciencedirect.com
    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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      RRID:AB_2756376

      DOI: 10.1016/j.ccell.2019.06.009

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    sciencedirect.com/science/article/pii/S1535610819303009
  135. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_2756376

      DOI: 10.1016/j.cmet.2019.02.001

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    sciencedirect.com/science/article/pii/S1550413119300658
  136. www.sciencedirect.com www.sciencedirect.com
    Inhibition of LTA4H by bestatin in human and mouse colorectal cancer
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    1. scibot 12 Jan 2020
      RRID:AB_2756376

      DOI: 10.1016/j.ebiom.2019.05.008

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    sciencedirect.com/science/article/pii/S2352396419303093