85 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
    1
    1. scibot 16 Apr 2024
      RRID:AB_2756376

      DOI: 10.1016/j.cell.2024.03.019

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    sciencedirect.com/science/article/pii/S0092867424003106
  3. www.sciencedirect.com www.sciencedirect.com
    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114088

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    sciencedirect.com/science/article/pii/S2211124724004169
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
    1
    1. scibot 03 Apr 2024
      RRID:AB_2756376

      DOI: 10.1158/1078-0432.CCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  5. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
      RRID:AB_2756376

      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  6. Mar 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.isci.2024.109366

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951988/
  8. 52.53.155.43 52.53.155.43
    Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.
    1
    1. scibot 12 Mar 2024
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      DOI: 10.1016/j.omton.2024.200766

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    52.53.155.43/8c6eb3b4d009a4f511a3160975bf106d9641ff9c/1-s2.0-S2950329924000080-main-html.html
  9. Feb 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
    1
    1. scibot 15 Feb 2024
      RRID:AB_275637

      DOI: 10.1158/2767-9764.CRC-23-0399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
  11. Jan 2024
  12. link.springer.com link.springer.com
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
    1
    1. scibot 25 Jan 2024
      RRID:AB_2756376

      DOI: 10.1038/s41388-024-02947-z

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    link.springer.com/article/10.1038/s41388-024-02947-z
  13. www.sciencedirect.com www.sciencedirect.com
    Multi-omics of the gut microbial ecosystem in patients with microsatellite-instability-high gastrointestinal cancer resistant to immunotherapy
    1
    1. scibot 09 Jan 2024
      RRID:AB_2756376

      DOI: 10.1016/j.xcrm.2023.101355

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    sciencedirect.com/science/article/pii/S2666379123005724
  14. www.sciencedirect.com www.sciencedirect.com
    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
    2
    1. scibot 04 Jan 2024
      RRID:AB_2756376

      DOI: 10.1016/j.devcel.2023.07.025

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    2. scibot 04 Jan 2024
      RRID:AB_2756376

      DOI: 10.1016/j.devcel.2023.07.025

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    sciencedirect.com/science/article/pii/S1534580723003945
  15. Dec 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
    1
    1. scibot 20 Dec 2023
      RRID:AB_2756376

      DOI: 10.1158/0008-5472.CAN-23-1065

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    ncbi.nlm.nih.gov/pmc/articles/PMC10722136/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
    1
    1. scibot 15 Dec 2023
      RRID:AB_2756376

      DOI: 10.1158/2159-8290.CD-23-0306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10714140/
  18. www.sciencedirect.com www.sciencedirect.com
    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
    1
    1. scibot 02 Dec 2023
      RRID:AB_2756376

      DOI: 10.1016/j.immuni.2023.11.002

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    sciencedirect.com/science/article/pii/S1074761323004831
  19. 52.53.155.43 52.53.155.43
    cd-23-0306-html.html
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1158/2159-8290.cd-23-0306

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    52.53.155.43/2d1591f4bcff82c10886f9ef5d1f22c1addeb365/cd-23-0306-html.html
  20. 52.53.155.43 52.53.155.43
    can-23-1065-html.html
    2
    1. scibot 01 Dec 2023
      RRID:AB_2756376

      DOI: 10.1158/0008-5472.can-23-1065

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    2. scibot 01 Dec 2023
      RRID:AB_2756376

      DOI: 10.1158/0008-5472.can-23-1065

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    52.53.155.43/9a4ebc518d925889ddaa33b397b4737aebb3357f/can-23-1065-html.html
  21. Nov 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
    1
    1. scibot 30 Nov 2023
      RRID:AB_2756376

      DOI: 10.1158/2767-9764.CRC-23-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
  23. www.sciencedirect.com www.sciencedirect.com
    FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation
    1
    1. scibot 17 Nov 2023
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.113362

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    sciencedirect.com/science/article/pii/S2211124723013748
  24. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
    1
    1. scibot 17 Nov 2023
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
  25. www.sciencedirect.com www.sciencedirect.com
    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
    1
    1. scibot 17 Nov 2023
      RRID:AB_2756376

      DOI: 10.1016/j.devcel.2023.10.010

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    sciencedirect.com/science/article/pii/S1534580723005518
  26. Oct 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 27 Oct 2023
      RRID:AB_2756376

      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  28. Aug 2023
  29. www.sciencedirect.com www.sciencedirect.com
    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
    1
    1. scibot 16 Aug 2023
      RRID:AB_2756376

      DOI: 10.1016/j.xcrm.2023.101154

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    sciencedirect.com/science/article/pii/S2666379123003075
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
    1
    1. scibot 12 Aug 2023
      RRID:AB_2756376

      DOI: 10.1038/s43856-023-00336-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
    1
    1. scibot 10 Aug 2023
      RRID:AB_2756376

      DOI: 10.1016/j.isci.2023.107408

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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  32. www.sciencedirect.com www.sciencedirect.com
    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
    1
    1. scibot 04 Aug 2023
      RRID:AB_2756376

      DOI: 10.1016/j.ccell.2021.02.007

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    sciencedirect.com/science/article/pii/S1535610821001094
  33. Jul 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
    1
    1. scibot 22 Jul 2023
      RRID:AB_2756376

      DOI: 10.1101/2023.06.27.546707

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    ncbi.nlm.nih.gov/pmc/articles/PMC10327161/
  35. Jun 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation
    1
    1. scibot 28 Jun 2023
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.112704

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    sciencedirect.com/science/article/pii/S2211124723007155
  37. www.sciencedirect.com www.sciencedirect.com
    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
    1
    1. scibot 28 Jun 2023
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.112693

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    sciencedirect.com/science/article/pii/S2211124723007040
  38. www.sciencedirect.com www.sciencedirect.com
    Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
    1
    1. scibot 03 Jun 2023
      RRID:AB_2756376

      DOI: 10.1016/j.isci.2023.106916

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    sciencedirect.com/science/article/pii/S2589004223009938
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
    1
    1. scibot 03 Jun 2023
      RRID:AB_2756376

      DOI: 10.1158/1535-7163.MCT-23-0039

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233358/
  40. 52.53.155.43 52.53.155.43
    mct-23-0039-html.html
    1
    1. scibot 01 Jun 2023
      AB_2756376

      DOI: 10.1158/1535-7163.MCT-23-0039

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    52.53.155.43/2e399e27445b3309b8dca3d6b15c5701e7dc6c5e/mct-23-0039-html.html
  41. May 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Small-molecule MHC-II inducers promote immune detection and anti-cancer immunity via editing cancer metabolism
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    1. scibot 26 May 2023
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      DOI: 10.1016/j.chembiol.2023.05.003

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    sciencedirect.com/science/article/pii/S2451945623001265
  43. www.sciencedirect.com www.sciencedirect.com
    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
    1
    1. scibot 26 May 2023
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      DOI: 10.1016/j.ccell.2023.04.018

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    sciencedirect.com/science/article/pii/S1535610823001629
  44. www.nature.com www.nature.com
    ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
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    1. scibot 20 May 2023
      RRID:AB_2756376

      DOI: 10.1038/s41467-023-38605-3

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    nature.com/articles/s41467-023-38605-3
  45. www.sciencedirect.com www.sciencedirect.com
    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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    1. scibot 18 May 2023
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      DOI: 10.1016/j.medj.2023.04.008

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    sciencedirect.com/science/article/pii/S266663402300140X
  46. insight.jci.org insight.jci.org
    Immune landscape of a genetically engineered murine model of glioma compared to human glioma by single-cell sequencing
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      DOI: 10.1172/jci.insight.148990

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    insight.jci.org/articles/view/148990
  47. www.sciencedirect.com www.sciencedirect.com
    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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    1. scibot 06 May 2023
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      DOI: 10.1016/j.devcel.2023.04.010

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    sciencedirect.com/science/article/pii/S1534580723001806
  48. www.sciencedirect.com www.sciencedirect.com
    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
    1
    1. scibot 03 May 2023
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      DOI: 10.1016/j.chom.2023.04.010

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    sciencedirect.com/science/article/abs/pii/S1931312823001610
  49. Apr 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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    1. scibot 14 Apr 2023
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      DOI: 10.1016/j.ccell.2023.03.015

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    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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    Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
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  53. Mar 2023
  54. europepmc.org europepmc.org
    Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity
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  55. Jan 2023
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    The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
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    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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  58. Dec 2022
  59. 52.53.155.43 52.53.155.43
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  60. Nov 2022
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    Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy
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  62. Sep 2022
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    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
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    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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  65. Aug 2022
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    Fasting renders immunotherapy effective against low-immunogenic breast cancer while reducing side effects
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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  68. Jul 2022
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    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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  70. Jun 2022
  71. 52.53.155.43 52.53.155.43
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  72. 52.53.155.43 52.53.155.43
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  73. May 2022
  74. www.sciencedirect.com www.sciencedirect.com
    Topical therapy for regression and melanoma prevention of congenital giant nevi
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    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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  76. Apr 2022
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  78. Mar 2022
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  81. Feb 2022
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    ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression
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  83. Dec 2021
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  85. Sep 2021
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    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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    Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
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  88. Aug 2021
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  90. Jun 2021
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    NF1 mutation drives neuronal activity-dependent initiation of optic glioma
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  92. May 2021
  93. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [64Cu]Cu-NOTA-anti-CD8-Positron Emission Tomography
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    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
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    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
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  96. Apr 2021
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    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
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    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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  100. Mar 2021
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    Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model
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    Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
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  103. Feb 2021
  104. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Peptides Derived From Insulin Granule Proteins are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice.
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  105. www.cell.com www.cell.com
    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
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  106. Jan 2021
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    Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing
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  108. Sep 2020
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
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      DOI: 10.1016/j.celrep.2020.01.008

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      RRIDCUR:Validated RRID:AB_2756376
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    cell.com/cell-reports/abstract/S2211-1247(20)30017-6
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    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    1. scibot 15 Sep 2020
      RRID:AB_2756376

      DOI: 10.1016/j.ccell.2019.12.006

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      RRIDCUR:Validated RRID:AB_2756376
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    sciencedirect.com/science/article/pii/S1535610819305768
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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      DOI: 10.1016/j.stem.2020.02.001

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    sciencedirect.com/science/article/pii/S1934590920300540
  113. Jan 2020
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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    1. scibot 13 Jan 2020
      RRID:AB_2756376

      DOI: 10.1016/j.ccell.2019.06.009

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    sciencedirect.com/science/article/pii/S1535610819303009
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    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2756376

      DOI: 10.1016/j.cmet.2019.02.001

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    sciencedirect.com/science/article/pii/S1550413119300658
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    Inhibition of LTA4H by bestatin in human and mouse colorectal cancer
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      DOI: 10.1016/j.ebiom.2019.05.008

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      RRID:AB_2756376 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2352396419303093