Hypothesis

29 Matching Annotations

Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeted KRASG12V Degradation in vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis

1
1. scibot 17 Jun 2026
  
  in Public
  
  AB_2773715
  
  DOI: 10.1158/0008-5472.CAN-25-5172
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC7619155/
Apr 2026
www.sciencedirect.com www.sciencedirect.com

Tumor-intrinsic FDFT1 determines coordinated macrophage anti-tumor immunity

1
1. scibot 30 Apr 2026
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.devcel.2026.04.003
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580726001504
Mar 2026
www.sciencedirect.com www.sciencedirect.com

A senescent tumor cell-derived nanovesicle directly primes splenic T cells to potentiate cancer radiotherapy

1
1. scibot 31 Mar 2026
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.xcrm.2026.102709
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379126001266
www.sciencedirect.com www.sciencedirect.com

Targeting the noncanonical function of metabolic enzyme PHGDH in driving PD-L1 expression and cancer immune evasion

1
1. scibot 31 Mar 2026
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.xcrm.2026.102704
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379126001217
Feb 2026
journals.plos.org journals.plos.org

The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model

1
1. scibot 03 Feb 2026
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1371/journal.pbio.3003603
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

journals.plos.org/plosbiology/article
Jan 2026
www.sciencedirect.com www.sciencedirect.com

p57 increases immunotherapy efficacy by promoting cGAS-STING-mediated innate sensing in hepatocellular carcinoma

1
1. scibot 09 Jan 2026
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2025.116769
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725015414
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Attenuated Salmonella secreting interleukin-21 activates T-cells and induces anti-tumor effects

1
1. scibot 18 Sep 2025
  
  in Public
  
  AB_213480
  
  DOI: 10.1016/j.apsb.2025.09.025
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715 RRIDCUR:Unresolved
Visit annotations in context

Tags

RRID:AB_2773715

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211383525006264
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

1
1. scibot 11 Mar 2025
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.ccell.2025.02.014
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610825000662
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

1
1. scibot 02 Dec 2024
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2024.115015
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724013664
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy

1
1. scibot 07 Nov 2024
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.3389/fonc.2024.1441935
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
Aug 2024
www.cell.com www.cell.com

Cyclin dependent kinase 9 inhibition reduced programmed death-ligand 1 expression and improved treatment efficacy in hepatocellular carcinoma

1
1. scibot 13 Aug 2024
  
  in Public
  
  RRID: AB_2773715
  
  DOI: 10.1016/j.heliyon.2024.e34289
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715 DOI:10.1016/j.heliyon.2024.e34289
Visit annotations in context

Tags

RRID:AB_2773715

DOI:10.1016/j.heliyon.2024.e34289

Annotators

scibot

URL

cell.com/heliyon/fulltext/S2405-8440(24)10320-9
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

1
1. scibot 25 Jul 2024
  
  in Public
  
  AB_2773715
  
  DOI: 10.1016/j.celrep.2024.114532
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724008611
www.sciencedirect.com www.sciencedirect.com

Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE2 production

1
1. scibot 12 Jul 2024
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2024.114469
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724007988
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

1
1. scibot 29 Mar 2024
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.chembiol.2024.02.013
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945624000874
Feb 2024
www.sciencedirect.com www.sciencedirect.com

UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity

1
1. scibot 28 Feb 2024
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.molcel.2024.01.024
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524000911
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Preventive Treatment with PD-1 Antibody Increases Tissue-Resident Memory T Cells Infiltration and Delays Esophageal Carcinogenesis

1
1. scibot 06 Dec 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1158/1940-6207.CAPR-23-0196
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10690045/
52.53.155.43 52.53.155.43

capr-23-0196-html.html

1
1. scibot 01 Dec 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1158/1940-6207.capr-23-0196
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

52.53.155.43/8688d597d2cc530cc7819d6b999768e8b625fdef/capr-23-0196-html.html
Nov 2023
www.sciencedirect.com www.sciencedirect.com

E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2023.113477
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723014894
www.sciencedirect.com www.sciencedirect.com

PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652

1
1. scibot 02 Nov 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2023.113343
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723013554
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Targeting VCP potentiates immune checkpoint therapy for colorectal cancer

1
1. scibot 27 Oct 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2023.113318
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472301330X
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.xcrm.2023.101206
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379123003737
Apr 2023
www.nature.com www.nature.com

Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy

1
1. scibot 11 Apr 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1038/s41467-023-37617-3
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

nature.com/articles/s41467-023-37617-3
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer

1
1. scibot 11 Feb 2023
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2023.112090
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723001018
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mammary tumor-derived transplants as breast cancer models to evaluate tumor-immune interactions and therapeutic responses

1
1. scibot 04 Aug 2022
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1158/0008-5472.CAN-21-0253
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8813892/
Jul 2022
www.sciencedirect.com www.sciencedirect.com

Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING mediated T cell activation

1
1. scibot 13 Jul 2022
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.isci.2022.104690
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222009622
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes

1
1. scibot 29 Jun 2022
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.celrep.2022.111011
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722008002
Feb 2022
www.sciencedirect.com www.sciencedirect.com

ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression

1
1. scibot 02 Feb 2022
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.devcel.2022.01.002
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580722000028
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

1
1. scibot 28 Apr 2021
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.molcel.2021.03.037
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727652100232X
Sep 2020
www.sciencedirect.com www.sciencedirect.com

ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis

1
1. scibot 14 Sep 2020
  
  in Public
  
  RRID:AB_2773715
  
  DOI: 10.1016/j.ccell.2020.02.006
  
  Resource: (Abcam Cat# ab213480, RRID:AB_2773715)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2773715
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2773715
Visit annotations in context

Tags

RRID:AB_2773715

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820300957