72 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.034

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    sciencedirect.com/science/article/pii/S0092867424005786
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    Tmem30a Protects Against Podocyte Injury Through Suppression of Pyroptosis
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    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109976

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    sciencedirect.com/science/article/pii/S2589004224011982
  4. May 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
    1
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    sciencedirect.com/science/article/pii/S2211124721002011
  6. 52.53.155.43 52.53.155.43
    Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke
    2
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      DOI: 10.1016/j.xcrm.2024.101522

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    2. scibot 07 May 2024
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      DOI: 10.1016/j.xcrm.2024.101522

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    52.53.155.43/23904a6df569543355b93537b87aff6dc46e4387/mmc2-html.html
  7. Apr 2024
  8. www.sciencedirect.com www.sciencedirect.com
    NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
    2
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      DOI: 10.1016/j.celrep.2024.114070

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    2. scibot 09 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114070

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    sciencedirect.com/science/article/pii/S221112472400398X
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Subventricular zone stem cell niche injury is associated with intestinal perforation in preterm infants and predicts future motor impairment
    1
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      DOI: 10.1016/j.stem.2024.03.001

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    sciencedirect.com/science/article/pii/S1934590924000821
  11. www.sciencedirect.com www.sciencedirect.com
    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
    2
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      DOI: 10.1016/j.celrep.2024.113981

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    2. scibot 29 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113981

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    sciencedirect.com/science/article/pii/S2211124724003097
  12. www.sciencedirect.com www.sciencedirect.com
    A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.celrep.2024.114004

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    sciencedirect.com/science/article/pii/S2211124724003322
  13. link.springer.com link.springer.com
    Effects of the Glucocorticoid-Mediated Mitochondrial Translocation of Glucocorticoid Receptors on Oxidative Stress and Pyroptosis in BV-2 Microglia
    1
    1. scibot 15 Mar 2024
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      DOI: 10.1007/s12031-024-02192-9

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    link.springer.com/article/10.1007/s12031-024-02192-9
  14. www.sciencedirect.com www.sciencedirect.com
    Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome
    2
    1. scibot 12 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113935

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    2. scibot 12 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113935

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    sciencedirect.com/science/article/pii/S2211124724002638
  15. Feb 2024
  16. www.sciencedirect.com www.sciencedirect.com
    SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination
    2
    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113752

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    2. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113752

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    sciencedirect.com/science/article/pii/S2211124724000809
  17. Dec 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
    1
    1. scibot 28 Dec 2023
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      DOI: 10.4103/1673-5374.385309

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    ncbi.nlm.nih.gov/pmc/articles/PMC10749599/
  19. www.sciencedirect.com www.sciencedirect.com
    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113581

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    sciencedirect.com/science/article/pii/S2211124723015930
  20. www.sciencedirect.com www.sciencedirect.com
    Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.xcrm.2023.101245

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    sciencedirect.com/science/article/pii/S2666379123004226
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.immuni.2023.10.004

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    sciencedirect.com/science/article/pii/S1074761323004442
  23. www.nature.com www.nature.com
    Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1038/s41467-023-43180-8

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    nature.com/articles/s41467-023-43180-8
  24. Jul 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112869

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    sciencedirect.com/science/article/pii/S221112472300880X
  26. Jun 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced Neural Stem Cells Suppressed Neuroinflammation by Inhibiting the Microglial Pyroptotic Pathway in Intracerebral Hemorrhage Rats
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.isci.2023.107022

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    ncbi.nlm.nih.gov/pmc/articles/PMC10285565/
  28. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.027

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    sciencedirect.com/science/article/pii/S0092867423005779
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    Whole-genome CRISPR screen identifies RAVER1 regulates RIPK1-mediated inflammatory cell death, PANoptosis
    1
    1. scibot 09 Jun 2023
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      DOI: 10.1016/j.isci.2023.106938

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    sciencedirect.com/science/article/pii/S2589004223010155
  30. www.sciencedirect.com www.sciencedirect.com
    NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
    1
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      DOI: 10.1016/j.cell.2023.05.005

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    sciencedirect.com/science/article/pii/S009286742300524X
  31. May 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response
    1
    1. scibot 19 May 2023
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      DOI: 10.1016/j.celrep.2023.112522

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    sciencedirect.com/science/article/pii/S2211124723005338
  33. www.sciencedirect.com www.sciencedirect.com
    Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome
    1
    1. scibot 18 May 2023
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      DOI: 10.1016/j.isci.2023.106758

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    sciencedirect.com/science/article/pii/S2589004223008350
  34. www.sciencedirect.com www.sciencedirect.com
    Engineer a double team of short-lived and glucose-sensing bacteria for cancer eradication
    1
    1. scibot 17 May 2023
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      DOI: 10.1016/j.xcrm.2023.101043

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    sciencedirect.com/science/article/pii/S266637912300157X
  35. Mar 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.immuni.2023.02.014

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    sciencedirect.com/science/article/pii/S1074761323000882
  37. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
    1
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      DOI: 10.1016/j.celrep.2023.112265

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    pubmed.ncbi.nlm.nih.gov/36930645/
  38. www.sciencedirect.com www.sciencedirect.com
    Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
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      DOI: 10.1016/j.neuron.2023.02.019

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    sciencedirect.com/science/article/pii/S089662732300123X
  39. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16036

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16036
  40. Feb 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation
    1
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      DOI: 10.1016/j.immuni.2023.01.015

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    sciencedirect.com/science/article/pii/S1074761323000250
  42. Jan 2023
  43. www.science.org www.science.org
    Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
    1
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      DOI: 10.1126/scisignal.abh1083

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    science.org/doi/10.1126/scisignal.abh1083
  44. www.sciencedirect.com www.sciencedirect.com
    Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
    1
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      DOI: 10.1016/j.celrep.2022.111965

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    sciencedirect.com/science/article/pii/S2211124722018691
  45. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D pore-forming activity is redox-sensitive
    1
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      DOI: 10.1016/j.celrep.2023.112008

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    sciencedirect.com/science/article/pii/S2211124723000190
  46. www.sciencedirect.com www.sciencedirect.com
    The NLRP1 and CARD8 inflammasomes detect reductive stress
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      DOI: 10.1016/j.celrep.2022.111966

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    sciencedirect.com/science/article/pii/S2211124722018708
  47. Dec 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
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      DOI: 10.7554/eLife.78609

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    ncbi.nlm.nih.gov/pmc/articles/PMC9754625/
  49. Nov 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
    1
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      DOI: 10.1016/j.celrep.2022.111688

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    sciencedirect.com/science/article/pii/S2211124722015625
  51. www.science.org www.science.org
    Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
    1
    1. scibot 15 Nov 2022
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      DOI: 10.1126/sciadv.abn9912

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    science.org/doi/10.1126/sciadv.abn9912
  52. Oct 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade
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      DOI: 10.1016/j.celrep.2022.111553

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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
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  55. Sep 2022
  56. www.sciencedirect.com www.sciencedirect.com
    The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways
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  57. Aug 2022
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury
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  59. May 2022
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    A TLR4-independent critical role for CD14 in intracellular LPS sensing
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  61. Mar 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon
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  63. Feb 2022
  64. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
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  65. Nov 2021
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    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
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  67. Oct 2021
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    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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  69. Sep 2021
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    Inappropriate use of antibiotics exacerbates inflammation through OMV-induced pyroptosis in MDR Klebsiella pneumoniae infection
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  71. Aug 2021
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  73. May 2021
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    Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties
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  75. Apr 2021
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    Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense
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    Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
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  78. Mar 2021
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    Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
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    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
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    Itaconate confers tolerance to late NLRP3 inflammasome activation
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  82. Feb 2021
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    A comprehensive guide to studying inflammasome activation and cell death
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  84. Dec 2020
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
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  86. Nov 2020
  87. elifesciences.org elifesciences.org
    LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation
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    RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly
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  89. Oct 2020
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    Activation of the CARD8 Inflammasome Requires a Disordered Region
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  91. Sep 2020
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    A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling
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    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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    Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection
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    β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
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    Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
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    mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury
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  98. Jan 2020
  99. iovs.arvojournals.org iovs.arvojournals.org
    Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal
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      DOI: 10.1016/j.immuni.2019.04.017

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