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Chromatin remodeling activity of EP400 safeguards chromosomal stability by preventing CENP-A mislocalization

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  DOI: 10.1016/j.celrep.2025.116423
  
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sciencedirect.com/science/article/pii/S2211124725011945
Aug 2025
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SLC4A11 is a targetable marker correlated with therapeutic responses in ovarian cancer

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1. scibot 01 Aug 2025
  
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  DOI: 10.1186/s13048-025-01758-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12309138/
Jun 2025
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Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor

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1. scibot 14 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102133
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147910/
May 2025
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Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102133
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147910/
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 19 Apr 2025
  
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  DOI: 10.1158/1535-7163.mct-24-0756
  
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52.53.155.43/a9bdac937b5d56e963502c7a9aeebc7cca17a770/PDF-html.html
Jan 2025
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The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC

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1. scibot 28 Jan 2025
  
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5’-cap-dependent translation as a potent therapeutic target for lethal human squamous cell carcinoma

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1. scibot 10 Jan 2025
  
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  Cyclin E1
  
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jidonline.org/article/S0022-202X(20)32066-2/fulltext
Oct 2024
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PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer

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1. scibot 04 Oct 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443213/
Sep 2024
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UA influences the progression of breast cancer via the AhR/p27Kip1/cyclin E pathway

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1. scibot 26 Sep 2024
  
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  DOI: 10.1096/fj.202400938R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400938R
Jul 2024
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A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC

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1. scibot 31 Jul 2024
  
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  DOI: 10.1158/2767-9764.CRC-24-0247
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
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Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor

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1. scibot 04 Jul 2024
  
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  DOI: 10.1101/2024.06.11.598518
  
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biorxiv.org/content/10.1101/2024.06.11.598518v2
Jun 2024
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CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer

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1. scibot 29 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.109978
  
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cell.com/iscience/abstract/S2589-0042(24)01200-8
May 2024
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Mecp2 fine-tunes quiescence exit by targeting nuclear receptors

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1. scibot 17 May 2024
  
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  DOI: 10.7554/eLife.89912
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
Mar 2024
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Light-mediated intracellular polymerization

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1. scibot 26 Mar 2024
  
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  DOI: 10.1038/s41596-024-00970-8
  
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nature.com/articles/s41596-024-00970-8
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First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.02.023
  
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sciencedirect.com/science/article/pii/S0092867424002253
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INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors

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1. scibot 06 Mar 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0954
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
Feb 2024
52.53.155.43 52.53.155.43

cd-23-0954-html.html

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1. scibot 27 Feb 2024
  
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  DOI: 10.1158/2159-8290.cd-23-0954
  
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52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html
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Alternative mRNA splicing events and regulators in epidermal differentiation

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1. scibot 27 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113814
  
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2. scibot 27 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113814
  
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sciencedirect.com/science/article/pii/S2211124724001426
Nov 2023
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ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury

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1. scibot 22 Nov 2023
  
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  DOI: 10.1038/s41467-023-43439-0
  
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nature.com/articles/s41467-023-43439-0
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Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers

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1. scibot 03 Nov 2023
  
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  DOI: 10.1158/1078-0432.CCR-23-0103
  
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pubmed.ncbi.nlm.nih.gov/37279095/
Oct 2023
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ccr-23-0103-html.html

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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Sep 2023
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Neuromedin B receptor as a potential therapeutic target for corticotroph adenomas

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1. scibot 07 Sep 2023
  
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  DOI: 10.1007/s11102-023-01350-3
  
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link.springer.com/article/10.1007/s11102-023-01350-3
Aug 2023
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ccr-23-0103-html.html

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1. scibot 11 Aug 2023
  
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  DOI: 10.1158/1078-0432.ccr-23-0103
  
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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Jul 2023
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ccr-23-0103-html.html

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1. scibot 08 Jul 2023
  
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  DOI: 10.1158/1078-0432.ccr-23-0103
  
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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Jan 2023
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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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1. scibot 26 Jan 2023
  
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  DOI: 10.1016/j.molcel.2022.12.034
  
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sciencedirect.com/science/article/pii/S1097276522012175
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Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling

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1. scibot 24 Jan 2023
  
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The human pre-replication complex is an open complex

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  DOI: 10.1016/j.cell.2022.12.008
  
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sciencedirect.com/science/article/pii/S0092867422015215
Dec 2022
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YAP regulates the liver size during the fasting-refeeding transition in mice

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1. scibot 24 Dec 2022
  
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sciencedirect.com/science/article/pii/S2211383522005196
Nov 2022
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RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

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  DOI: 10.1016/j.isci.2022.105184
  
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sciencedirect.com/science/article/pii/S2589004222014560
Jul 2022
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LRH-1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance

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1. scibot 09 Jul 2022
  
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  DOI: 10.15252/embr.202154195
  
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embopress.org/doi/10.15252/embr.202154195
Mar 2022
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Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Affects Neurogenesis in Mouse Brain

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  DOI: 10.1016/j.brainresbull.2022.02.019
  
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sciencedirect.com/science/article/pii/S0361923022000582
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

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1. scibot 17 Dec 2021
  
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  DOI: 10.7554/eLife.70691
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
Nov 2021
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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109934
  
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sciencedirect.com/science/article/pii/S2211124721014078
Oct 2021
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A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle

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1. scibot 19 Oct 2021
  
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  DOI: 10.1016/j.cub.2021.09.050
  
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sciencedirect.com/science/article/pii/S0960982221012902
Sep 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models

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1. scibot 25 Sep 2021
  
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  RRID:AB_2783554
  
  DOI: 10.1016/j.xcrm.2021.100394
  
  Resource: (Cell Signaling Technology Cat# 20808, RRID:AB_2783554)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2783554
  
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  RRID:AB_2783554
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pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
Jun 2021
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miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3

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1. scibot 09 Jun 2021
  
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  RRID: AB_2783554
  
  DOI: 10.1016/j.celrep.2021.109225
  
  Resource: (Cell Signaling Technology Cat# 20808, RRID:AB_2783554)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124721005763
Oct 2020
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Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo

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1. scibot 22 Oct 2020
  
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  RRID:AB_2783554
  
  DOI: 10.1016/j.molmet.2020.101085
  
  Resource: (Cell Signaling Technology Cat# 20808, RRID:AB_2783554)
  
  Curator: @Naa003
  
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  RRID:AB_2783554 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2212877820301599
Jan 2020
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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

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1. scibot 13 Jan 2020
  
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  RRID:AB_2783554
  
  DOI: 10.1016/j.ccell.2019.11.003
  
  Resource: (Cell Signaling Technology Cat# 20808, RRID:AB_2783554)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2783554
  
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  RRID:AB_2783554 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819305239