60 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109828

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    sciencedirect.com/science/article/pii/S2589004224010502
  3. May 2024
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    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.ebiom.2024.105162

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    sciencedirect.com/science/article/pii/S235239642400197X
  5. Apr 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Repurposing AS1411 for constructing ANM-PROTACs
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    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.chembiol.2024.03.011

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    sciencedirect.com/science/article/pii/S2451945624001272
  7. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  8. Mar 2024
  9. www.nature.com www.nature.com
    Monolayer culture alters EGFR inhibitor response through abrogation of microRNA-mediated feedback regulation
    1
    1. scibot 28 Mar 2024
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      DOI: 10.1038/s41598-024-56920-7

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    nature.com/articles/s41598-024-56920-7
  10. Nov 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113417

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    sciencedirect.com/science/article/pii/S2211124723014298
  12. Oct 2023
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
    1
    1. scibot 12 Oct 2023
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      DOI: 10.1158/2767-9764.CRC-23-0089

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561629/
  14. Aug 2023
  15. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101142

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  16. Jul 2023
  17. www.sciencedirect.com www.sciencedirect.com
    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112833

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    sciencedirect.com/science/article/pii/S2211124723008446
  18. Jun 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer
    1
    1. scibot 22 Jun 2023
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      DOI: 10.1158/2767-9764.CRC-23-0030

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    ncbi.nlm.nih.gov/pmc/articles/PMC10281290/
  20. www.sciencedirect.com www.sciencedirect.com
    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112654

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    sciencedirect.com/science/article/pii/S2211124723006654
  21. May 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Modeling human ectopic pregnancies with trophoblast and vascular organoids
    1
    1. scibot 24 May 2023
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      DOI: 10.1016/j.celrep.2023.112546

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    sciencedirect.com/science/article/pii/S2211124723005570
  23. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
    1
    1. scibot 13 May 2023
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      DOI: 10.1016/j.celrep.2023.112479

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    sciencedirect.com/science/article/pii/S2211124723004904
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    Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.ccell.2023.04.011

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    sciencedirect.com/science/article/pii/S153561082300137X
  25. Apr 2023
  26. www.sciencedirect.com www.sciencedirect.com
    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
    1
    1. scibot 22 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112372

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    sciencedirect.com/science/article/pii/S2211124723003832
  27. Mar 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction
    1
    1. scibot 16 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112252

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    sciencedirect.com/science/article/pii/S2211124723002632
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sustained oncogenic signaling in the cytostatic state enables targeting of non-proliferating persistent cancer cells
    1
    1. scibot 05 Mar 2023
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      DOI: 10.1158/0008-5472.CAN-21-2908

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444958/
  30. Feb 2023
  31. academic.oup.com academic.oup.com
    STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1210/endocr/bqac215

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    academic.oup.com/endo/article/164/3/bqac215/6967061
  32. www.sciencedirect.com www.sciencedirect.com
    Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1016/j.xcrm.2023.100934

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    sciencedirect.com/science/article/pii/S2666379123000265
  33. Jan 2023
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis
    1
    1. scibot 31 Jan 2023
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      DOI: 10.1002/hipo.23502

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    onlinelibrary.wiley.com/doi/10.1002/hipo.23502
  35. www.sciencedirect.com www.sciencedirect.com
    The human placenta shapes the phenotype of decidual macrophages
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111977

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    sciencedirect.com/science/article/pii/S2211124722018812
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anlotinib Suppressed Ovarian Cancer Progression via Inducing G2/M Phase Arrest and Apoptosis
    1
    1. scibot 11 Jan 2023
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      DOI: 10.3390/jcm12010162

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    ncbi.nlm.nih.gov/pmc/articles/PMC9821756/
  37. Dec 2022
  38. www.sciencedirect.com www.sciencedirect.com
    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
    1
    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111819

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    sciencedirect.com/science/article/pii/S2211124722017119
  39. Nov 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts
    1
    1. scibot 18 Nov 2022
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      DOI: 10.1016/j.ccell.2022.10.021

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    sciencedirect.com/science/article/pii/S1535610822005128
  41. Oct 2022
  42. www.sciencedirect.com www.sciencedirect.com
    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111561

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    sciencedirect.com/science/article/pii/S221112472201422X
  43. www.sciencedirect.com www.sciencedirect.com
    Spatial epitope barcoding reveals clonal tumor patch behaviors
    1
    1. scibot 16 Oct 2022
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      DOI: 10.1016/j.ccell.2022.09.014

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    sciencedirect.com/science/article/pii/S1535610822004433
  44. Sep 2022
  45. www.sciencedirect.com www.sciencedirect.com
    CDK14 inhibition reduces mammary stem cell activity and suppresses triple negative breast cancer progression
    1
    1. scibot 15 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111331

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    sciencedirect.com/science/article/pii/S2211124722011597
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A
    1
    1. scibot 08 Sep 2022
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      DOI: 10.1016/j.isci.2022.104952

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    ncbi.nlm.nih.gov/pmc/articles/PMC9440292/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
    1
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      DOI: 10.1158/2159-8290.CD-21-0694

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
  48. Aug 2022
  49. 52.53.155.43 52.53.155.43
    can-21-2908-html.html
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    1. scibot 27 Aug 2022
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      DOI: 10.1158/0008-5472.can-21-2908

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    52.53.155.43/e58395037b6fc963ccf3afdad25ef582040a5a24/can-21-2908-html.html
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    GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming
    1
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      DOI: 10.1016/j.jcmgh.2022.06.009

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    sciencedirect.com/science/article/pii/S2352345X22001552
  51. Jul 2022
  52. www.sciencedirect.com www.sciencedirect.com
    METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma
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    1. scibot 08 Jul 2022
      CST, #9449

      DOI: 10.1016/j.ebiom.2022.104142

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    sciencedirect.com/science/article/pii/S2352396422003231
  53. May 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
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      DOI: 10.1016/j.stem.2022.04.004

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    sciencedirect.com/science/article/pii/S1934590922001576
  55. Mar 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTPN2 elicits cell autonomous and non–cell autonomous effects on antitumor immunity in triple-negative breast cancer
    1
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      DOI: 10.1126/sciadv.abk3338

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    ncbi.nlm.nih.gov/pmc/articles/PMC8865802/
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
    1
    1. scibot 09 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110473

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    sciencedirect.com/science/article/pii/S2211124722002066
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
    1
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      DOI: 10.1016/j.celrep.2022.110425

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    sciencedirect.com/science/article/pii/S2211124722001498
  59. Feb 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration
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      DOI: 10.1016/j.neuron.2022.01.018

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.neuron.2022.01.018

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    sciencedirect.com/science/article/pii/S0896627322000575
  61. Nov 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
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      DOI: 10.1016/j.celrep.2021.109957

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    sciencedirect.com/science/article/pii/S2211124721014340
  63. Oct 2021
  64. www.sciencedirect.com www.sciencedirect.com
    ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells
    1
    1. scibot 27 Oct 2021
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2021.109880

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    sciencedirect.com/science/article/pii/S2211124721013504
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
    1
    1. scibot 20 Oct 2021
      RRID:AB_2797703

      DOI: 10.1158/0008-5472.CAN-21-1545

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    ncbi.nlm.nih.gov/pmc/articles/PMC8723353/
  66. Aug 2021
  67. www.sciencedirect.com www.sciencedirect.com
    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
    1
    1. scibot 17 Aug 2021
      9449

      DOI: 10.1016/j.apsb.2021.08.015

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    sciencedirect.com/science/article/pii/S2211383521003051
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53
    1
    1. scibot 05 Aug 2021
      RRID:AB_2797703

      DOI: 10.7554/eLife.70429

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    ncbi.nlm.nih.gov/pmc/articles/PMC8321552/
  69. Jul 2021
  70. www.nature.com www.nature.com
    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
    1
    1. scibot 22 Jul 2021
      9449s

      DOI: 10.1038/s41388-021-01869-4

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    nature.com/articles/s41388-021-01869-4
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lower androgen levels promote abnormal cartilage development in female patients with adolescent idiopathic scoliosis
    2
    1. scibot 16 Jul 2021
      RRID: AB_2797703

      DOI: 10.21037/atm-20-3171

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    2. scibot 16 Jul 2021
      RRID:AB_2797703

      DOI: 10.21037/atm-20-3171

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    ncbi.nlm.nih.gov/pmc/articles/PMC8246169/
  72. May 2021
  73. peerj.com peerj.com
    Brain-derived neurotrophic factor increases cell number of neural progenitor cells derived from human induced pluripotent stem cells
    1
    1. scibot 19 May 2021
      RRID:AB_2797703

      DOI: 10.7717/peerj.11388

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  74. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
    1
    1. scibot 05 May 2021
      RRID:AB_2797703

      DOI: 10.1016/j.devcel.2020.07.014

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    sciencedirect.com/science/article/pii/S1534580720305888
  75. Apr 2021
  76. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma
    1
    1. scibot 22 Apr 2021
      KI67

      DOI: 10.1016/j.ccell.2020.08.014

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    sciencedirect.com/science/article/pii/S1535610820304256
  77. Feb 2021
  78. www.nature.com www.nature.com
    Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress
    1
    1. scibot 26 Feb 2021
      anti-Ki67

      DOI: 10.1038/s42255-020-00325-z

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    nature.com/articles/s42255-020-00325-z
  79. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 24 Feb 2021
      RRID:AB_2797703

      DOI: 10.1111/bph.14985

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14985
  80. Nov 2020
  81. link.springer.com link.springer.com
    p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound
    1
    1. scibot 25 Nov 2020
      anti-Ki67

      DOI: 10.1007/s10571-020-01006-x

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    link.springer.com/article/10.1007/s10571-020-01006-x
  82. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    1. scibot 10 Nov 2020
      RRID:AB_2797703

      DOI: 10.1002/1878-0261.12820

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12820
  83. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity
    1
    1. scibot 04 Nov 2020
      RRID:AB_2797703

      DOI: 10.1186/s12935-020-01598-w

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    cancerci.biomedcentral.com/article/10.1186/s12935-020-01598-w
  84. Oct 2020
  85. www.cell.com www.cell.com
    Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
    1
    1. scibot 24 Oct 2020
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2020.108286

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    cell.com/cell-reports/abstract/S2211-1247(20)31275-4
  86. Sep 2020
  87. www.nature.com www.nature.com
    Zinc-finger antiviral protein acts as a tumor suppressor in colorectal cancer
    1
    1. scibot 16 Sep 2020
      RRID:AB_2797703

      DOI: 10.1038/s41388-020-01416-7

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    nature.com/articles/s41388-020-01416-7
  88. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
    1
    1. scibot 03 Sep 2020
      Ki-67

      DOI: 10.1016/j.celrep.2020.108092

      Resource: (Cell Signaling Technology Cat# 9449, RRID:AB_2797703)

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    pubmed.ncbi.nlm.nih.gov/32877674/
  89. Jan 2020
  90. www.sciencedirect.com www.sciencedirect.com
    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
    1
    1. scibot 13 Jan 2020
      RRID:AB_2797703

      DOI: 10.1016/j.cmet.2019.06.014

      Resource: (Cell Signaling Technology Cat# 9449, RRID:AB_2797703)

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    sciencedirect.com/science/article/pii/S1550413119303171
  91. www.sciencedirect.com www.sciencedirect.com
    Maturation of the Human Intestinal Immune System Occurs Early in Fetal Development
    1
    1. scibot 13 Jan 2020
      RRID:AB_2797703

      DOI: 10.1016/j.devcel.2019.09.008

      Resource: (Cell Signaling Technology Cat# 9449, RRID:AB_2797703)

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    sciencedirect.com/science/article/pii/S1534580719307373