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Mutant KRAS-driven selective mRNA translation reveals mechanisms and therapeutic vulnerabilities in cancer

1
1. scibot 13 Jun 2026
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.celrep.2026.117520
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
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  RRID:AB_2797893
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sciencedirect.com/science/article/pii/S221112472600598X
Apr 2026
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USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma

1
1. scibot 29 Apr 2026
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.celrep.2026.117328
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S2211124726004067
Nov 2025
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Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia

1
1. scibot 22 Nov 2025
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.cell.2025.10.028
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S0092867425012334
Jun 2025
www.cell.com www.cell.com

Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.cmet.2025.05.009
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
Apr 2025
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Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance

1
1. scibot 11 Apr 2025
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.ccell.2025.03.031
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S1535610825001321
Mar 2025
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Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism

1
1. scibot 20 Mar 2025
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.cmet.2025.02.008
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S155041312500066X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair

1
1. scibot 14 Mar 2025
  
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  RRID:AB_2797893
  
  DOI: 10.1126/sciadv.adt1241
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11900879/
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Hypoxia inducible factor-1α drives cancer resistance to cuproptosis

1
1. scibot 07 Mar 2025
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.ccell.2025.02.015
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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  RRID:AB_2797893
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sciencedirect.com/science/article/pii/S1535610825000674
Apr 2024
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Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases

1
1. scibot 26 Apr 2024
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.xcrm.2024.101523
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S2666379124001927
Mar 2024
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Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide

1
1. scibot 08 Mar 2024
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.molcel.2023.12.033
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S1097276523010791
Nov 2023
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Targeting cuproptosis by zinc pyrithione in triple-negative breast cancer

1
1. scibot 02 Nov 2023
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.isci.2023.108218
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S2589004223022952
Oct 2023
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Lactate activates the mitochondrial electron transport chain independently of its metabolism

1
1. scibot 28 Oct 2023
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.molcel.2023.09.034
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2797893
  
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sciencedirect.com/science/article/pii/S1097276523008006
Mar 2021
www.cell.com www.cell.com

The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity

1
1. scibot 03 Mar 2021
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.cmet.2021.02.007
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2797893
  
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  RRIDCUR:Validated RRID:AB_2797893
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RRID:AB_2797893

RRIDCUR:Validated

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cell.com/cell-metabolism/fulltext/S1550-4131(21)00063-2
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

1
1. scibot 09 Sep 2020
  
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  RRID:AB_279789
  
  DOI: 10.7554/eLife.58041
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2797893
  
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  RRIDCUR:Incorrect RRIDCUR:Unresolved RRID:AB_2797893
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RRID:AB_2797893

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ncbi.nlm.nih.gov/pmc/articles/PMC7470841/
Jan 2020
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Untitled document

1
1. scibot 12 Jan 2020
  
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  RRID:AB_2797893
  
  DOI: 10.1016/j.celrep.2019.04.005
  
  Resource: (Cell Signaling Technology Cat# 12362, RRID:AB_2797893)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2797893
  
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  RRID:AB_2797893 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2797893

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sciencedirect.com/science/article/pii/S2211124719304607