14 Matching Annotations
  1. Feb 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pharmacokinetic-pharmacodynamic-efficacy modeling of the MDM2 inhibitor brigimadlin in glioblastoma patient-derived xenografts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12883205/
  3. www.sciencedirect.com www.sciencedirect.com
    Proteomics landscape of early T-cell precursor acute lymphoblastic leukemia reveals deficient oxidative phosphorylation signatures
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    sciencedirect.com/science/article/pii/S2666379126000030
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant CDK4/6-driven cell-cycle reentry drives neuronal loss and defines a therapeutic target in C9orf72 ALS/FTD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12856326/
  5. Sep 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-clinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-wildtype Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402800/
  7. Aug 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
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    ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
  9. Oct 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570680/
  11. Nov 2022
  12. aacrjournals.org aacrjournals.org
    p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness
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    aacrjournals.org/clincancerres/article/28/21/4757/709842/p53-Inhibits-Bmi-1-driven-Self-Renewal-and-Defines
  13. Oct 2022
  14. 52.53.155.43 52.53.155.43
    ccr-22-1357-html.html
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    52.53.155.43/b06e31323fa05ae99a3ee4406ee4cfeac8533d8b/ccr-22-1357-html.html
  15. Apr 2022
  16. www.sciencedirect.com www.sciencedirect.com
    Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations
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    sciencedirect.com/science/article/pii/S2211124722003709
  17. Oct 2021
  18. www.sciencedirect.com www.sciencedirect.com
    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
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    sciencedirect.com/science/article/pii/S2211124721012791
  19. Aug 2021
  20. www.sciencedirect.com www.sciencedirect.com
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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    sciencedirect.com/science/article/pii/S1535610821003834
  21. link.springer.com link.springer.com
    Ribosomal L1 domain-containing protein 1 coordinates with HDM2 to negatively regulate p53 in human colorectal Cancer cells
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    link.springer.com/article/10.1186/s13046-021-02057-8
  22. Jul 2021
  23. www.sciencedirect.com www.sciencedirect.com
    Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target
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    sciencedirect.com/science/article/pii/S1357272521001060
  24. Feb 2021
  25. www.sciencedirect.com www.sciencedirect.com
    Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site
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    sciencedirect.com/science/article/pii/S153561082030605X