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Identification of an STING inhibitor targeting the allosteric transmembrane domains

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1. scibot 29 Apr 2026
  
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  DOI: 10.1016/j.chembiol.2026.04.001
  
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sciencedirect.com/science/article/pii/S2451945626001108
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Protocol for the isolation and characterization of extracellular vesicles and particles from human and murine cell lines

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.xpro.2026.104505
  
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sciencedirect.com/science/article/pii/S2666166726001589
Dec 2025
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Dual roles of TRPV2 in the innate immune response to cytosolic DNA: Arresting dormant and boosting activated STING

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1. scibot 18 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116745
  
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sciencedirect.com:5037/science/article/pii/S2211124725015177
Nov 2025
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The lipid droplet protein DHRS3 is a regulator of melanoma cell state

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1. scibot 01 Nov 2025
  
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  DOI: 10.1111/pcmr.13208
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12244328/
Oct 2025
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Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma

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1. scibot 28 Oct 2025
  
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sciencedirect.com/science/article/pii/S2211124725012318
Sep 2025
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A role for CASM in the repair of damaged Golgi architecture

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1. scibot 20 Sep 2025
  
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  DOI: 10.1101/2025.09.04.674289
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12424704/
Aug 2025
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Extracellular vesicle manufacture via FACTORY: fully automated collection technology and optimum machinery for clinical translational applications

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  DOI: 10.1016/j.tibtech.2025.06.020
  
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sciencedirect.com/science/article/pii/S0167779925002598
Jun 2025
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Rapid hepatitis C virus replication machinery removal after antiviral treatment with DAA monitored by multimodal imaging

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1. scibot 18 Jun 2025
  
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sciencedirect.com/science/article/pii/S0969212625001935
Feb 2025
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BACE1-dependent cleavage of GABAA receptor contributes to neural hyperexcitability and disease progression in Alzheimer’s disease

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.neuron.2025.01.030
  
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sciencedirect.com/science/article/pii/S0896627325000789
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A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation

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  DOI: 10.1016/j.molcel.2025.01.003
  
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sciencedirect.com/science/article/pii/S1097276525000036
Dec 2024
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  DOI: 10.1172/jci183592
  
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52.53.155.43/6223e1a34d8b418f72131b1eba207b1427b70260/PDF-html.html
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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.cels.2024.11.004
  
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sciencedirect.com/science/article/pii/S2405471224003375
Sep 2024
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Zika virus NS3 drives the assembly of a viroplasm-like structure

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1. scibot 29 Sep 2024
  
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  DOI: 10.1101/2024.09.16.613201
  
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biorxiv.org/content/10.1101/2024.09.16.613201v1
Aug 2024
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Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors

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1. scibot 01 Aug 2024
  
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  DOI: 10.1016/j.devcel.2024.07.003
  
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sciencedirect.com/science/article/pii/S1534580724004428
Jul 2024
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TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging

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1. scibot 25 Jul 2024
  
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  DOI: 10.1080/15548627.2024.2333717
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11262205/
Jun 2024
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Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.devcel.2024.05.011
  
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Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114316
  
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sciencedirect.com/science/article/pii/S2211124724006442
May 2024
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Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.isci.2024.109860
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11108982/
Apr 2024
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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

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1. scibot 28 Apr 2024
  
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  DOI: 10.1101/2024.04.07.588166
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030420/
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Trafficking of Connexin36 (Cx36) in the early secretory pathway

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1. scibot 18 Apr 2024
  
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  DOI: 10.1101/2024.03.25.586643
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10996632/
Jan 2024
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Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.isci.2024.108801
  
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sciencedirect.com/science/article/pii/S2589004224000221
Oct 2023
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MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis

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1. scibot 06 Oct 2023
  
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cell.com/cell-reports/abstract/S2211-1247(23)01034-3
Jun 2023
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The intracellular C-terminal domain of mGluR6 contains ER retention motifs

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1. scibot 22 Jun 2023
  
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  DOI: 10.1016/j.mcn.2023.103875
  
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Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage

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1. scibot 22 Jun 2023
  
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  DOI: 10.1126/sciadv.adf6600
  
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science.org/doi/10.1126/sciadv.adf6600
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Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage

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1. scibot 17 Jun 2023
  
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  DOI: 10.1126/sciadv.adf6600
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10266735/
May 2023
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Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity

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1. scibot 04 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112447
  
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Apr 2023
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ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion

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1. scibot 13 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.03.014
  
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Feb 2023
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HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy

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1. scibot 17 Feb 2023
  
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  DOI: 10.1158/2326-6066.CIR-22-0277
  
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aacrjournals.org/cancerimmunolres/article/11/2/228/716209/HRS-Regulates-Small-Extracellular-Vesicle-PD-L1
Jan 2023
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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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  DOI: 10.1016/j.molcel.2022.12.034
  
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SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2

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sciencedirect.com/science/article/pii/S2211124722018885
Dec 2022
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The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER

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  DOI: 10.1016/j.celrep.2022.111868
  
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sciencedirect.com/science/article/pii/S2211124722017648
Sep 2022
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Target protein localization and its impact on PROTAC-mediated degradation

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  DOI: 10.1016/j.chembiol.2022.08.004
  
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sciencedirect.com/science/article/pii/S2451945622003129
Aug 2022
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STK25 inhibits PKA signaling by phosphorylating PRKAR1A

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  DOI: 10.1016/j.celrep.2022.111203
  
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sciencedirect.com/science/article/pii/S2211124722010208
Jul 2022
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FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111101
  
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sciencedirect.com/science/article/pii/S2211124722009032
Aug 2021
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Localization, proteomics, and metabolite profiling reveal a putative vesicular transporter for UDP-glucose

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1. scibot 25 Aug 2021
  
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  DOI: 10.7554/eLife.65417
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8373376/
Jul 2021
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Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis

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1. scibot 30 Jul 2021
  
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  GM130
  
  DOI: 10.1021/acsnano.9b04397
  
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Delivering progranulin to neuronal lysosomes protects against excitotoxicity

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1. scibot 24 Jul 2021
  
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  12480
  
  DOI: 10.1016/j.jbc.2021.100993
  
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May 2021
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ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes

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1. scibot 26 May 2021
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.celrep.2021.109178
  
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Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells

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1. scibot 19 May 2021
  
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  RRID:AB_2797933
  
  DOI: 10.1126/sciadv.abe8349
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8104865/
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ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

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1. scibot 08 May 2021
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.molcel.2021.03.001
  
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NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

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1. scibot 06 May 2021
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.devcel.2020.11.016
  
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Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications

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1. scibot 05 May 2021
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.devcel.2020.11.007
  
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Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells

1
1. scibot 30 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.10.025
  
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Jan 2021
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

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1. scibot 26 Jan 2021
  
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  DOI: 10.1016/j.cell.2020.12.024
  
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Nov 2020
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Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies

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1. scibot 28 Nov 2020
  
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  DOI: 10.1016/j.chom.2020.11.003
  
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Sep 2020
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Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies

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1. scibot 23 Sep 2020
  
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  AB_2797933
  
  DOI: 10.1080/20013078.2020.1812261
  
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APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.celrep.2020.02.064
  
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Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis

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1. scibot 17 Sep 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.chembiol.2020.04.003
  
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Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

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1. scibot 16 Sep 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1038/s41467-019-14085-2
  
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Transferrin Receptor Is a Specific Ferroptosis Marker

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1. scibot 13 Sep 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.celrep.2020.02.049
  
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2. scibot 03 Sep 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.celrep.2020.02.049
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7172030/
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The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting

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1. scibot 07 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107944
  
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Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression

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1. scibot 06 Sep 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.molcel.2020.01.014
  
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journals.plos.org journals.plos.org

JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor

1
1. scibot 04 Sep 2020
  
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  GM130
  
  DOI: 10.1371/journal.ppat.1008371
  
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journals.plos.org/plospathogens/article
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Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.04.013
  
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Jan 2020
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Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.cell.2019.07.002
  
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Mechanical Stabilization of the Glandular Acinus by Linker of Nucleoskeleton and Cytoskeleton Complex

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  RRID:AB_2797933
  
  DOI: 10.1016/j.cub.2019.07.021
  
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A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_2797933
  
  DOI: 10.1016/j.cmet.2019.11.020
  
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cell.com/cell-metabolism/fulltext/S1550-4131(19)30664-3